Patents by Inventor Sami Karaborni

Sami Karaborni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions of dimethyl fumarate
    Patent number: 11229621
    Abstract: Pharmaceutical compositions and dosage forms of dimethyl fumarate containing low levels of certain impurities are disclosed.
    Type: Grant
    Filed: January 22, 2020
    Date of Patent: January 25, 2022
    Assignee: Arbor Pharmaceuticals, LLC
    Inventors: Sami Karaborni, Wei Chen, Suresh Kumar Manthati
  • PHARMACEUTICAL GRANULATIONS OF WATER-SOLUBLE ACTIVE PHARMACEUTICAL INGREDIENTS
    Publication number: 20210393537
    Abstract: Granulations with granules having a high loading of an active pharmaceutical ingredient are disclosed. The active pharmaceutical ingredient has a high aqueous water solubility. The granules have a narrow particle size distribution and a smooth exterior surface.
    Type: Application
    Filed: June 17, 2021
    Publication date: December 23, 2021
    Inventors: Sami KARABORNI, William W. XIANG, Daniel M. CANAFAX, Jia-Ning XIANG
  • CONTROLLED RELEASE GRANULATIONS OF WATER-SOLUBLE ACTIVE PHARMACEUTICAL INGREDIENTS
    Publication number: 20210393529
    Abstract: Pharmaceutical granulations having a functional coating surrounding a core containing a water-soluble active pharmaceutical ingredient are disclosed. The functional coating provides for immediate release or controlled release of the active pharmaceutical ingredient. The pharmaceutical granulations can be used in oral pharmaceutical compositions.
    Type: Application
    Filed: June 17, 2021
    Publication date: December 23, 2021
    Inventors: SAMI KARABORNI, DANIEL M. CANAFAX, JIA-NING XIANG, WILLIAM W. XIANG, JAMES TIEN
  • Pharmaceutical compositions of fumaric acid esters
    Patent number: 11135296
    Abstract: Pharmaceutical compositions and dosage forms of (N,N-diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate and/or methyl 4-morpholin-4-ylbutyl (2E)but-2-ene-1,4-dioate, containing low levels of certain impurities are disclosed.
    Type: Grant
    Filed: May 15, 2018
    Date of Patent: October 5, 2021
    Assignee: Arbor Pharmaceuticals, LLC
    Inventors: Suresh Kumar Manthati, Sami Karaborni, Wei Chen
  • Methods of Administering Monomethyl Fumarate and Prodrugs Thereof Having Reduced Side Effects
    Publication number: 20210228525
    Abstract: Methods of reducing undesirable side effects during therapeutic treatment using monomethyl fumarate and prodrugs of monomethyl fumarate are disclosed.
    Type: Application
    Filed: February 3, 2021
    Publication date: July 29, 2021
    Inventors: Kenneth C. Cundy, Sami Karaborni, Peter A. Virsik
  • ORAL DOSAGE FORMS OF METHYL HYDROGEN FUMARATE AND PRODRUGS THEREOF
    Publication number: 20210145755
    Abstract: Improved oral dosage forms of methyl hydrogen fumarate and prodrugs thereof are disclosed. Methods of treating diseases such as multiple sclerosis and psoriasis using such dosage forms are also disclose.
    Type: Application
    Filed: January 27, 2021
    Publication date: May 20, 2021
    Inventors: Sami Karaborni, Sarina Grace Harris Ma, Chen Mao, Ching Wah Chong, Peter Robert Prinz Freed, Mesut Ciper, Stefanie Krenzlin, David Wustrow, Peter Virsik
  • Crystalline form of an avibactam derivative
    Patent number: 11008321
    Abstract: A crystalline form of an avibactam derivative, pharmaceutical compositions thereof, and the use of the crystalline avibactam derivative for treating bacterial infections are provided.
    Type: Grant
    Filed: March 10, 2020
    Date of Patent: May 18, 2021
    Assignee: Arixa Pharmaceuticals, Inc.
    Inventor: Sami Karaborni
  • CORTICOTROPIN RELEASING FACTOR RECEPTOR ANTAGONISTS
    Publication number: 20210137935
    Abstract: The present invention provides novel pharmaceutical compositions comprising 3-(4-Chloro-2-(morpholin-4-yl)thiazol-5-yl)-7-(1-ethylpropyl)-2,5-dimethylpyrazolo(1,5-a)pyrimidine and methods of using the same for the treatment of Congenital adrenal hyperplasia (CAH).
    Type: Application
    Filed: August 14, 2018
    Publication date: May 13, 2021
    Applicant: Spruce Biosciences, Inc.
    Inventors: Alexis HOWERTON, Hal GERBER, Sami KARABORNI
  • CRYSTALLINE FORMS OF C-C CHEMOKINE RECEPTOR TYPE 4 ANTAGONIST AND USES THEREOF
    Publication number: 20210139487
    Abstract: Crystalline forms of a C-C chemokine receptor type 4 (CCR4) antagonist, oral dosage forms of same and methods of using and preparing same, are provided.
    Type: Application
    Filed: November 13, 2020
    Publication date: May 13, 2021
    Inventors: David J. ARNOLD, Omar ROBLES, Duane E. RUDISILL, David J. WUSTROW, Mikhail ZIBINSKY, Sami KARABORNI
  • SOLID FORMS OF CERDULATINIB
    Publication number: 20210130330
    Abstract: Forms of cerdulatinib and salts or co-crystals thereof were prepared and characterized in the solid state. Also provided are processes of manufacture and methods of using the forms cerdulatinib and salts or co-crystals thereof.
    Type: Application
    Filed: November 16, 2020
    Publication date: May 6, 2021
    Inventors: Anjali Pandey, Julian Scott Northen, Philippe Fernandes, Ying Chen, Yuelie Lu, Sami Karaborni, Gus Kodersha
  • Methods of administering monomethyl fumarate and prodrugs thereof having reduced side effects
    Patent number: 10945984
    Abstract: Methods of reducing undesirable side effects during therapeutic treatment using monomethyl fumarate and prodrugs of monomethyl fumarate are disclosed.
    Type: Grant
    Filed: August 22, 2013
    Date of Patent: March 16, 2021
    Assignee: Arbor Pharmaceuticals, LLC
    Inventors: Kenneth C. Cundy, Sami Karaborni, Peter A. Virsik
  • Oral dosage forms of methyl hydrogen fumarate and prodrugs thereof
    Patent number: 10940117
    Abstract: Improved oral dosage forms of methyl hydrogen fumarate and prodrugs thereof are disclosed. Methods of treating diseases such as multiple sclerosis and psoriasis using such dosage forms are also disclose.
    Type: Grant
    Filed: April 20, 2020
    Date of Patent: March 9, 2021
    Assignee: Arbor Pharmaceuticals, LLC
    Inventors: Sami Karaborni, Sarina Grace Harris Ma, Chen Mao, Ching Wah Chong, Peter Robert Prinz Freed, Mesut Ciper, Stefanie Krenzlin, David J. Wustrow, Peter A. Virsik
  • Solid forms of cerdulatinib
    Patent number: 10865198
    Abstract: Forms of cerdulatinib and salts or co-crystals thereof were prepared and characterized in the solid state. Also provided are processes of manufacture and methods of using the forms cerdulatinib and salts or co-crystals thereof.
    Type: Grant
    Filed: May 3, 2019
    Date of Patent: December 15, 2020
    Assignee: Alexion Pharmaceuticals, Inc.
    Inventors: Anjali Pandey, Julian Scott Northen, Philippe Fernandes, Ying Chen, Yuelie Lu, Sami Karaborni, Gus Kodersha
  • CRYSTALLINE FORM OF AN AVIBACTAM DERIVATIVE
    Publication number: 20200291022
    Abstract: A crystalline form of an avibactam derivative, pharmaceutical compositions thereof, and the use of the crystalline avibactam derivative for treating bacterial infections are provided.
    Type: Application
    Filed: March 10, 2020
    Publication date: September 17, 2020
    Applicant: ARIXA PHARMACEUTICALS, INC.
    Inventor: Sami Karaborni
  • CORTICOTROPIN RELEASING FACTOR RECEPTOR ANTAGONISTS
    Publication number: 20200255436
    Abstract: The present disclosure provides forms of CRF antagonists and methods using such CRF antagonists for treating diseases.
    Type: Application
    Filed: February 11, 2020
    Publication date: August 13, 2020
    Inventors: Alexis HOWERTON, Hal GERBER, Sami KARABORNI, Sangita GHOSH
  • ORAL DOSAGE FORMS OF METHYL HYDROGEN FUMARATE AND PRODRUGS THEREOF
    Publication number: 20200246271
    Abstract: Improved oral dosage forms of methyl hydrogen fumarate and prodrugs thereof are disclosed. Methods of treating diseases such as multiple sclerosis and psoriasis using such dosage forms are also disclose.
    Type: Application
    Filed: April 20, 2020
    Publication date: August 6, 2020
    Inventors: Sami Karaborni, Sarina Grace Harris Ma, Chen Mao, Ching Wah Chong, Peter Robert Prinz Freed, Mesut Ciper, Stefanie Krenzlin, David J. Wustrow, Peter A. Virsik
  • Oral dosage forms of methyl hydrogen fumarate and prodrugs thereof
    Patent number: 10716760
    Abstract: Improved oral dosage forms of methyl hydrogen fumarate and prodrugs thereof are disclosed. Methods of treating diseases such as multiple sclerosis and psoriasis using such dosage forms are also disclose.
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: July 21, 2020
    Assignee: Arbor Pharmaceuticals, LLC
    Inventors: Sami Karaborni, Sarina Grace Harris Ma, Chen Mao, Ching Wah Chong, Peter Robert Prinz Freed, Mesut Ciper, Stefanie Krenzlin, David J. Wustrow, Peter A. Virsik
  • Pharmaceutical Compositions of Dimethyl Fumarate
    Publication number: 20200155496
    Abstract: Pharmaceutical compositions and dosage forms of dimethyl fumarate containing low levels of certain impurities are disclosed.
    Type: Application
    Filed: January 22, 2020
    Publication date: May 21, 2020
    Inventors: Sami Karaborni, Wei Chen, Suresh Kumar Manthati
  • Pharmaceutical compositions of dimethyl fumarate
    Patent number: 10576055
    Abstract: Pharmaceutical compositions and dosage forms of dimethyl fumarate containing low levels of certain impurities are disclosed.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: March 3, 2020
    Assignee: Arbor Pharmaceuticals, LLC
    Inventors: Sami Karaborni, Wei Chen, Suresh Kumar Manthati
  • SOLID FORMS OF CERDULATINIB
    Publication number: 20200031804
    Abstract: Forms of cerdulatinib and salts or co-crystals thereof were prepared and characterized in the solid state. Also provided are processes of manufacture and methods of using the forms cerdulatinib and salts or co-crystals thereof.
    Type: Application
    Filed: May 3, 2019
    Publication date: January 30, 2020
    Inventors: Anjali Pandey, Julian Scott Northen, Philippe Fernandes, Ying Chen, Yuelie Lu, Sami Karaborni, Gus Kodersha