Patents by Inventor Sami Karaborni

Sami Karaborni has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oral Dosage Forms Of Methyl Hydrogen Fumarate And Prodrugs Thereof
    Publication number: 20200000758
    Abstract: Methods of treating psoriasis with sustained release compression coated tablet dosage forms comprising certain MHF prodrugs are provided.
    Type: Application
    Filed: September 10, 2019
    Publication date: January 2, 2020
    Inventors: Peter A. Virsik, Sami Karaborni, Laura Elizabeth Bauer, Chen Mao, Ching Wah Chong
  • Pharmaceutical Compositions of Dimethyl Fumarate
    Publication number: 20190091196
    Abstract: Pharmaceutical compositions and dosage forms of dimethyl fumarate containing low levels of certain impurities are disclosed.
    Type: Application
    Filed: November 30, 2018
    Publication date: March 28, 2019
    Inventors: Sami Karaborni, Wei Chen, Suresh Kumar Manthati
  • Pharmaceutical compositions of dimethyl fumarate
    Patent number: 10179118
    Abstract: Pharmaceutical compositions and dosage forms of dimethyl fumarate containing low levels of certain impurities are disclosed.
    Type: Grant
    Filed: March 24, 2014
    Date of Patent: January 15, 2019
    Assignee: ARBOR PHARMACEUTICALS, LLC
    Inventors: Sami Karaborni, Wei Chen, Suresh Kumar Manthati
  • Pharmaceutical compositions of fumaric acid esters
    Patent number: 9999672
    Abstract: Pharmaceutical compositions and dosage forms of (N,N-diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate and/or methyl 4-morpholin-4-ylbutyl (2E)but-2-ene-1,4-dioate, containing low levels of certain impurities are disclosed.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: June 19, 2018
    Assignee: XENOPORT, INC.
    Inventors: Suresh Kumar Manthati, Sami Karaborni, Wei Chen
  • Crystalline forms of (N, N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate, methods of synthesis and use
    Patent number: 9895336
    Abstract: Disclosed herein are crystalline forms of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate, which is a prodrug of methyl hydrogen fumarate. Crystalline form 1, Crystalline form 2, Crystalline 3, and Crystalline form 4 are disclosed.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: February 20, 2018
    Assignee: XENOPORT, INC.
    Inventors: Chen Mao, Randall A. Scheuerman, Sami Karaborni
  • CRYSTALLINE FORMS OF (N, N-DIETHYLCARBAMOYL)METHYL METHYL (2E)BUT-2-ENE-1,4-DIOATE, METHODS OF SYNTHESIS AND USE
    Publication number: 20170368014
    Abstract: Disclosed herein are crystalline forms of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate, which is a prodrug of methyl hydrogen fumarate. Crystalline form 1, Crystalline form 2, Crystalline 3, and Crystalline form 4 are disclosed.
    Type: Application
    Filed: September 6, 2017
    Publication date: December 28, 2017
    Inventors: Chen Mao, Randall A. Scheuerman, Sami Karaborni
  • Crystalline forms of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate, methods of synthesis and use
    Patent number: 9795581
    Abstract: Disclosed herein are crystalline forms of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate, which is a prodrug of methyl hydrogen fumarate. Crystalline form 1, Crystalline form 2, Crystalline 3, and Crystalline form 4 are disclosed.
    Type: Grant
    Filed: May 8, 2017
    Date of Patent: October 24, 2017
    Assignee: XENOPORT, INC.
    Inventors: Chen Mao, Randall A. Scheuerman, Sami Karaborni
  • CRYSTALLINE FORMS OF (N, N-DIETHYLCARBAMOYL)METHYL METHYL (2E)BUT-2-ENE-1,4-DIOATE, METHODS OF SYNTHESIS AND USE
    Publication number: 20170239206
    Abstract: Disclosed herein are crystalline forms of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate, which is a prodrug of methyl hydrogen fumarate. Crystalline form 1, Crystalline form 2, Crystalline 3, and Crystalline form 4 are disclosed.
    Type: Application
    Filed: May 8, 2017
    Publication date: August 24, 2017
    Inventors: Chen Mao, Randall A. Scheuerman, Sami Karaborni
  • Crystalline forms of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate, methods of synthesis and use
    Patent number: 9682057
    Abstract: Disclosed herein are crystalline forms of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate, which is a prodrug of methyl hydrogen fumarate. Crystalline form 1, Crystalline form 2, Crystalline 3, and Crystalline form 4 are disclosed.
    Type: Grant
    Filed: July 20, 2016
    Date of Patent: June 20, 2017
    Assignee: XENOPORT, INC.
    Inventors: Chen Mao, Randall A. Scheuerman, Sami Karaborni
  • ORAL DOSAGE FORMS OF METHYL HYDROGEN FUMARATE AND PRODRUGS THEREOF
    Publication number: 20170157056
    Abstract: Improved oral dosage forms of methyl hydrogen fumarate and prodrugs thereof are disclosed. Methods of treating diseases such as multiple sclerosis and psoriasis using such dosage forms are also disclose.
    Type: Application
    Filed: January 7, 2016
    Publication date: June 8, 2017
    Applicant: XENOPORT, INC.
    Inventors: Sami Karaborni, Sarina Grace Harris Ma, Chen Mao, Ching Wah Chong, Peter Robert Prinz Freed, Mesut Ciper, Stefanie Krenzlin, David J. Wustrow, Peter A. Virsik
  • Oral dosage forms of methyl hydrogen fumarate and prodrugs thereof
    Patent number: 9597292
    Abstract: Improved oral dosage forms of methyl hydrogen fumarate and prodrugs thereof are disclosed. Methods of treating diseases such as multiple sclerosis and psoriasis using such dosage forms are also disclosed.
    Type: Grant
    Filed: August 22, 2013
    Date of Patent: March 21, 2017
    Assignee: XenoPort, Inc.
    Inventors: Sami Karaborni, Sarina Grace Harris Ma, Chen Mao, Ching Wah Chong, Peter Robert Prinz Freed, Mesut Ciper, Stefanie Krenzlin, David J. Wustrow, Peter A. Virsik
  • CRYSTALLINE FORMS OF (N,N-DIETHYLCARBAMOYL)METHYL METHYL (2E)BUT-2-ENE-1,4-DIOATE, METHODS OF SYNTHESIS AND USE
    Publication number: 20170042853
    Abstract: Disclosed herein are crystalline forms of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate, which is a prodrug of methyl hydrogen fumarate. Crystalline form 1, Crystalline form 2, Crystalline 3, and Crystalline form 4 are disclosed.
    Type: Application
    Filed: July 20, 2016
    Publication date: February 16, 2017
    Applicant: XenoPort, Inc.
    Inventors: Chen Mao, Randall A. Scheuerman, Sami Karaborni
  • Oral Dosage forms having a High Loading of a Gabapentin Prodrug
    Publication number: 20170035714
    Abstract: Sustained release oral dosage forms with a high loading of a gabapentin prodrug are disclosed.
    Type: Application
    Filed: October 14, 2016
    Publication date: February 9, 2017
    Inventors: Sami Karaborni, Laura E. Maurer, David J. Kidney
  • Cocrystals of dimethyl fumarate
    Patent number: 9421182
    Abstract: Disclosed herein are cocrystals of dimethyl fumarate, which is a prodrug of methyl hydrogen fumarate.
    Type: Grant
    Filed: June 20, 2014
    Date of Patent: August 23, 2016
    Assignee: XenoPort, Inc.
    Inventors: Chen Mao, Scott L. Childs, Sami Karaborni
  • Crystalline forms of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate, methods of synthesis and use
    Patent number: 9416096
    Abstract: Disclosed herein are crystalline forms of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate, which is a prodrug of methyl hydrogen fumarate. Crystalline form 1, Crystalline form 2, Crystalline 3, and Crystalline form 4 are disclosed.
    Type: Grant
    Filed: September 5, 2014
    Date of Patent: August 16, 2016
    Assignee: XenoPort, Inc.
    Inventors: Chen Mao, Randall A. Scheuerman, Sami Karaborni
  • ORAL DOSAGE FORMS OF METHYL HYDROGEN FUMARATE AND PRODRUGS THEREOF
    Publication number: 20160113879
    Abstract: Improved oral dosage forms of methyl hydrogen fumarate and prodrugs thereof are disclosed. Methods of treating diseases such as multiple sclerosis and psoriasis using such dosage forms are also disclose.
    Type: Application
    Filed: January 7, 2016
    Publication date: April 28, 2016
    Applicant: XENOPORT, INC.
    Inventors: Sami Karaborni, Sarina Grace Harris Ma, Chen Mao, Ching Wah Chong, Peter Robert Prinz Freed, Mesut Ciper, Stefanie Krenzlin, David J. Wustrow, Peter A. Virsik
  • PHARMACEUTICAL COMPOSITIONS OF FUMARIC ACID ESTERS
    Publication number: 20150265707
    Abstract: Pharmaceutical compositions and dosage forms of (N,N-diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate and/or methyl 4-morpholin-4-ylbutyl (2E)but-2-ene-1,4-dioate, containing low levels of certain impurities are disclosed.
    Type: Application
    Filed: March 20, 2015
    Publication date: September 24, 2015
    Inventors: Suresh Kumar Manthati, Sami Karaborni, Wei Chen
  • NANOPARTICLE COMPOSITIONS OF DIMETHYL FUMARATE
    Publication number: 20150079180
    Abstract: Disclosed herein are compositions of dimethyl fumarate exhibiting reduced gastrointestinal irritation and related side effects.
    Type: Application
    Filed: September 18, 2014
    Publication date: March 19, 2015
    Inventors: Sami Karaborni, Chen Mao, Garry T. Gwozdz
  • CRYSTALLINE FORMS OF (N,N-DIETHYLCARBAMOYL)METHYL METHYL (2E)BUT-2-ENE-1,4-DIOATE, METHODS OF SYNTHESIS AND USE
    Publication number: 20150073049
    Abstract: Disclosed herein are crystalline forms of (N,N-Diethylcarbamoyl)methyl methyl (2E)but-2-ene-1,4-dioate, which is a prodrug of methyl hydrogen fumarate. Crystalline form 1, Crystalline form 2, Crystalline 3, and Crystalline form 4 are disclosed.
    Type: Application
    Filed: September 5, 2014
    Publication date: March 12, 2015
    Inventors: Chen Mao, Randall A. Scheuerman, Sami Karaborni
  • COCRYSTALS OF DIMETHYL FUMARATE
    Publication number: 20140378542
    Abstract: Disclosed herein are cocrystals of dimethyl fumarate, which is a prodrug of methyl hydrogen fumarate.
    Type: Application
    Filed: June 20, 2014
    Publication date: December 25, 2014
    Inventors: Chen Mao, Scott L. Childs, Sami Karaborni