Patents by Inventor Samuel Clark

Samuel Clark has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11958821
    Abstract: Disclosed herein are salts and solid forms of MDMA, (R)-MDMA, (S)-MDMA, MDE, S-MDE, R-MDE, MDAI, MBDB, S-MBDB, R-MBDB, MEAI, and 5,6-Dimethoxy-2-aminoindane, including salts, solid forms of the compound and salts thereof, as well as polymorphs of solid forms. The solid forms disclosed herein may have improved properties, such as improved physical, chemical, and/or pharmacokinetic properties. Also disclosed are methods for making the salts and solid forms and methods for administering the same. The disclosed salt and solid forms of MDMA, (R)-MDMA, (S)-MDMA, MDE, S-MDE, R-MDE, MDAI, MBDB, S-MBDB, R-MBDB, MEAI, and 5,6-Dimethoxy-2-aminoindane may be useful for treating neurological disease and/or a psychiatric disorder in a subject.
    Type: Grant
    Filed: February 28, 2023
    Date of Patent: April 16, 2024
    Assignee: Terran Biosciences Inc.
    Inventor: Samuel Clark
  • Patent number: 11945832
    Abstract: Disclosed herein are salts and solid-state forms of psilocybin, including psilocybin HCl, and salts and solid forms of O-acetylpsilocin, including O-acetylpsilocin fumarate. Also disclosed are methods for making the salts and solid forms and methods for administering the salts and solid forms. The salts and solid forms disclosed herein are useful for treating neurological disease and/or a psychiatric disorder in a subject.
    Type: Grant
    Filed: September 15, 2023
    Date of Patent: April 2, 2024
    Inventor: Samuel Clark
  • Publication number: 20240066423
    Abstract: Demonstration packaging for fidget toys and methods of assembling same are described.
    Type: Application
    Filed: August 29, 2023
    Publication date: February 29, 2024
    Inventors: Samuel K. Harwell, Jr., Craig Clark Williamson
  • Patent number: 11905295
    Abstract: Disclosed herein are salt and solid forms of tabernanthalog. Disclosed solid forms may be a polymorph of tabernanthalog fumarate, and/or may have improved properties, such as improved physical, chemical and/or pharmacokinetic properties. Disclosed salts include pharmaceutically acceptable salts of tabernanthalog. Disclosed solid forms include free base and salt forms of tabernanthalog, including amorphous and crystalline forms of tabernanthalog, such as tabernanthalog free base or a salt thereof. Also disclosed are methods for making the salts and solid forms and methods for administering the same. The salt and solid forms of tabernanthalog and salts thereof are useful for treating neurological disease and/or a psychiatric disorder in a subject.
    Type: Grant
    Filed: February 28, 2023
    Date of Patent: February 20, 2024
    Assignee: Terran Biosciences Inc.
    Inventor: Samuel Clark
  • Publication number: 20240034718
    Abstract: The present disclosure is directed to salt and solid forms of (R)-1-(5-METHOXY-1H-INDOL-1-YL)-N,N-DIMETHYLPROPAN-2-AMINE and methods of treating neurological disorder and/or a psychiatric disorder in a subject in need thereof.
    Type: Application
    Filed: March 2, 2023
    Publication date: February 1, 2024
    Inventors: Matthew DUNCTON, Samuel CLARK
  • Publication number: 20240010663
    Abstract: Disclosed herein are salts and solid-state forms of psilocybin, including psilocybin HCl, and salts and solid forms of O-acetylpsilocin, including O-acetylpsilocin fumarate. Also disclosed are methods for making the salts and solid forms and methods for administering the salts and solid forms. The salts and solid forms disclosed herein are useful for treating neurological disease and/or a psychiatric disorder in a subject.
    Type: Application
    Filed: September 15, 2023
    Publication date: January 11, 2024
    Inventor: Samuel CLARK
  • Publication number: 20240002337
    Abstract: The present disclosure is directed to salt and solid forms of (R)-1-(5-METHOXY-1H-INDOL-1-YL)-N,N-DIMETHYLPROPAN-2-AMINE and methods of treating neurological disorder and/or a psychiatric disorder in a subject in need thereof.
    Type: Application
    Filed: November 16, 2022
    Publication date: January 4, 2024
    Inventors: Matthew DUNCTON, Samuel CLARK
  • Patent number: 11851452
    Abstract: Disclosed herein are salts and solid state forms of psilocybin, including psilocybin HCl, and salts and solid forms of O-acetylpsilocin, including O-acetylpsilocin fumarate. Also disclosed are methods for making the salts and solid forms and methods for administering the salts and solid forms. The salts and solid forms disclosed herein are useful for treating neurological disease and/or a psychiatric disorder in a subject.
    Type: Grant
    Filed: December 28, 2022
    Date of Patent: December 26, 2023
    Assignee: TERRAN BIOSCIENCES INC.
    Inventor: Samuel Clark
  • Publication number: 20230389854
    Abstract: A neuromelanin sensitive magnetic resonance imaging (“MRI”) technique, method and computer-accessible medium for measuring the extent of, providing a diagnosis of, monitoring the treatment of, assessing novel treatments for, or determining a prognosis related to one or more neurological conditions.
    Type: Application
    Filed: May 15, 2023
    Publication date: December 7, 2023
    Inventors: Samuel CLARK, Clifford Mills CASSIDY, Pedro ROSA-NETO, Kenneth WENGLER, Guillermo HORGA HERNANDEZ
  • Publication number: 20230279017
    Abstract: Disclosed herein are salt and solid forms of tabernanthalog. Disclosed solid forms may be a polymorph of tabernanthalog fumarate, and/or may have improved properties, such as improved physical, chemical and/or pharmacokinetic properties. Disclosed salts include pharmaceutically acceptable salts of tabernanthalog. Disclosed solid forms include free base and salt forms of tabernanthalog, including amorphous and crystalline forms of tabernanthalog, such as tabernanthalog free base or a salt thereof. Also disclosed are methods for making the salts and solid forms and methods for administering the same. The salt and solid forms of tabernanthalog and salts thereof are useful for treating neurological disease and/or a psychiatric disorder in a subject.
    Type: Application
    Filed: February 28, 2023
    Publication date: September 7, 2023
    Inventors: Matthew DUNCTON, Samuel CLARK
  • Publication number: 20230257385
    Abstract: Disclosed herein are salt and solid forms of tabernanthalog. Disclosed solid forms may be a polymorph of tabernanthalog fumarate, and/or may have improved properties, such as improved physical, chemical and/or pharmacokinetic properties. Disclosed salts include pharmaceutically acceptable salts of tabernanthalog. Disclosed solid forms include free base and salt forms of tabernanthalog, including amorphous and crystalline forms of tabernanthalog, such as tabernanthalog free base or a salt thereof. Also disclosed are methods for making the salts and solid forms and methods for administering the same. The salt and solid forms of tabernanthalog and salts thereof are useful for treating neurological disease and/or a psychiatric disorder in a subject.
    Type: Application
    Filed: November 17, 2022
    Publication date: August 17, 2023
    Inventors: Matthew DUNCTON, Samuel CLARK
  • Publication number: 20230227422
    Abstract: Disclosed herein are salts and solid forms of MDMA, (R)-MDMA, (S)-MDMA, MDE, S-MDE, R-MDE, MDAI, MBDB, S-MBDB, R-MBDB, MEAI, and 5,6-Dimethoxy-2-aminoindane, including salts, solid forms of the compound and salts thereof, as well as polymorphs of solid forms. The solid forms disclosed herein may have improved properties, such as improved physical, chemical, and/or pharmacokinetic properties. Also disclosed are methods for making the salts and solid forms and methods for administering the same. The disclosed salt and solid forms of MDMA, (R)-MDMA, (S)-MDMA, MDE, S-MDE, R-MDE, MDAI, MBDB, S-MBDB, R-MBDB, MEAI, and 5,6-Dimethoxy-2-aminoindane may be useful for treating neurological disease and/or a psychiatric disorder in a subject.
    Type: Application
    Filed: February 28, 2023
    Publication date: July 20, 2023
    Inventors: Matthew DUNCTON, Samuel CLARK
  • Publication number: 20230202998
    Abstract: Disclosed herein are salts and solid forms of MDMA, (R)-MDMA, (S)-MDMA, MDE, S-MDE, R-MDE, MDAI, MBDB, S-MBDB, R-MBDB, MEAI, and 5,6-Dimethoxy-2-aminoindane, including salts, solid forms of the compound and salts thereof, as well as polymorphs of solid forms. The solid forms disclosed herein may have improved properties, such as improved physical, chemical, and/or pharmacokinetic properties. Also disclosed are methods for making the salts and solid forms and methods for administering the same. The disclosed salt and solid forms of MDMA, (R)-MDMA, (S)-MDMA, MDE, S-MDE, R-MDE, MDAI, MBDB, S-MBDB, R-MBDB, MEAI, and 5,6-Dimethoxy-2-aminoindane may be useful for treating neurological disease and/or a psychiatric disorder in a subject.
    Type: Application
    Filed: November 17, 2022
    Publication date: June 29, 2023
    Inventors: Matthew DUNCTON, Samuel CLARK
  • Publication number: 20230192642
    Abstract: Described herein are isotopically enriched analogs of methylone (e.g., deuterated analogs of methylone (e.g., (S)-methylone and (R)-methylone) with improved characteristics. Also described herein are salts (such as hydrochloride salt) and solid forms (e.g., crystalline forms) of methylone. Also described herein are stereoisomers (e.g., enantiomers) of methylone. The present disclosure also provides methods of making and methods of use of the methylone or methylone analogs and solid forms of 3,4-methylenedioxy-N-ethylcathinone hydrochloride described herein to treat brain and neurological disorders such as depression.
    Type: Application
    Filed: December 28, 2022
    Publication date: June 22, 2023
    Inventors: Matthew DUNCTON, Samuel CLARK, Alistair HENDERSON, Bernard GOLDING, Manuel MONERRIS MASCARO, Lucia JOHNSON, Annette MADRID
  • Publication number: 20230181521
    Abstract: Disclosed herein are isotopically enriched compounds and methods of using both isotopically and non-isotopically enriched compounds of the following formula in the treatment of neurologic and brain disorders/conditions.
    Type: Application
    Filed: November 7, 2022
    Publication date: June 15, 2023
    Inventors: Matthew DUNCTON, Samuel CLARK
  • Publication number: 20230159456
    Abstract: Disclosed herein are compounds of the formula as well as methods for their use in treating neurologic and brain disorders.
    Type: Application
    Filed: October 31, 2022
    Publication date: May 25, 2023
    Inventors: Matthew DUNCTON, Samuel Clark, John K. Dickson, Scott Miller
  • Publication number: 20230159544
    Abstract: Disclosed herein are compounds of Formulae I or II, or an isotopically enriched compound thereof, or a pharmaceutically acceptable salt thereof, methods for making the compounds, and methods for their use.
    Type: Application
    Filed: October 31, 2022
    Publication date: May 25, 2023
    Inventors: Matthew DUNCTON, Samuel Clark, Scott Miller
  • Publication number: 20230150920
    Abstract: Disclosed herein are salts and solid forms of 4-bromo-2,5-dimethoxyphenethylamine. The solid form may be a salt and/or a crystalline form of 4-bromo-2,5-dimethoxyphenethylamine, such as a polymorph of 4-bromo-2,5-dimethoxyphenethylamine or a salt thereof. Also disclosed are methods for making the salts and solid forms and methods for administering the solid forms. The salts and solid forms of 4-bromo-2,5-dimethoxyphenethylamine are useful for treating neurological disease and/or a psychiatric disorder in a subject.
    Type: Application
    Filed: November 15, 2022
    Publication date: May 18, 2023
    Inventors: Matthew DUNCTON, Samuel CLARK
  • Publication number: 20230151036
    Abstract: Disclosed herein are salts and solid state forms of psilocybin, including psilocybin HCl, and salts and solid forms of O-acetylpsilocin, including O-acetylpsilocin fumarate. Also disclosed are methods for making the salts and solid forms and methods for administering the salts and solid forms. The salts and solid forms disclosed herein are useful for treating neurological disease and/or a psychiatric disorder in a subject.
    Type: Application
    Filed: December 28, 2022
    Publication date: May 18, 2023
    Inventors: Matthew DUNCTON, Samuel CLARK
  • Publication number: 20230150965
    Abstract: Disclosed herein are isotopically enriched compounds and methods of using both isotopically and non-isotopically enriched compounds of the following formula in the treatment of neurologic and brain disorders/conditions.
    Type: Application
    Filed: November 7, 2022
    Publication date: May 18, 2023
    Inventors: Matthew DUNCTON, Samuel CLARK