Abstract: A medical device includes a shaft including a central lumen configured to direct a flow of fluid through the shaft, and an electrode positioned at a distal portion of the shaft. The electrode includes an electrode lumen in fluid communication with the central lumen, and the electrode lumen is configured to receive the flow of fluid from the central lumen. The electrode also includes one or more channels angled relative to the electrode lumen, and the one or more channels are in fluid communication with the electrode lumen to receive the flow of fluid from the electrode lumen. The one or more channels are configured to divert the flow of fluid from the electrode lumen toward one or more outlets laterally offset from the electrode lumen.

Abstract: Exemplary medical devices may include a snare device. The snare device may include a first leg having a proximalmost end and a second leg having a proximalmost end. The first leg and the second leg may form a distal loop. The proximalmost end of first leg may be independently moveable relative to the proximalmost end of the second leg.

Abstract: A device for passing a needle and suture longitudinally through a target tissue includes a proximal jaw including a proximal recess and a proximal retention mechanism for releasably engaging a first end of a needle received within the proximal recess and a distal jaw movably coupled to the proximal jaw such that the proximal and distal jaws are longitudinally movable relative to one another. The distal jaw includes a distal recess and a distal retention mechanism for releasably engaging a second end of the needle received within the distal recess. The proximal and distal jaws are movable between a first state, in which the proximal retention mechanism is in a locked configuration and the distal retention mechanism is in an unlocked configuration, and a second state, in which the proximal retention mechanism is in an unlocked configuration and the distal retention mechanism is in a locked configuration.

Abstract: A device for treating a tissue opening includes a proximal portion including an elongated flexible member, a capsule releasably coupled to a distal end of the flexible member and including a lumen extending therethrough and a clip including a pair of arms movably housed within the capsule. A suture extending along a first one of the pair of arms and including a loop at a distal end thereof extending across an opening extending through the first one of the pair of arms. A suture grabbing element extending laterally from a second one of the pair of arms and including a hook so that, when the pair of arms are moved toward a closed configuration, the hook extends through the opening to grab the loop and draw the distal end of the suture from the first one of the pair of arms toward the second one of the pair of arms.

Abstract: According to one aspect, a medical system may include an instrument including an end effector for acting as a monopolar electrode. The end effector may be configured to be positioned in a body of a subject and emit radiofrequency energy towards a target area in the body. The medical system may further include a return electrode. The return electrode may be deliverable within the body proximate the target area and separately from the instrument and the monopolar electrode. The return electrode may be configured to contact tissue in the body proximate the target area and receive radiofrequency energy emitted from the end effector.

Abstract: A medical device includes a shaft including a central lumen configured to direct a flow of fluid through the shaft, and an electrode positioned at a distal portion of the shaft. The electrode includes an electrode lumen in fluid communication with the central lumen, and the electrode lumen is configured to receive the flow of fluid from the central lumen. The electrode also includes one or more channels angled relative to the electrode lumen, and the one or more channels are in fluid communication with the electrode lumen to receive the flow of fluid from the electrode lumen. The one or more channels are configured to divert the flow of fluid from the electrode lumen toward one or more outlets laterally offset from the electrode lumen.

Abstract: The present disclosure relates to the field of tissue dissection. Specifically, the present disclosure relates to medical devices which lift and retract tissue during a dissection procedure to improve visualization of the target tissue and mitigate obstruction of dissection tools. In particular, the present disclosure relates to a tissue retraction device which moves from a constrained to relaxed configuration to immobilize and retract the dissected portion of target tissue during a dissection procedure.

Abstract: The present disclosure is directed to a medical instrument. The medical instrument may include a delivery device and a retraction mechanism including a target tissue anchor and a first stabilizing anchor, wherein the target tissue anchor attaches to target tissue and connects to the delivery device.

Abstract: The present disclosure relates to the field of tissue dissection. Specifically, the present disclosure relates to medical devices which lift and retract tissue during a dissection procedure to improve visualization of the target tissue and mitigate obstruction of dissection tools. In particular, the present disclosure relates to a tissue retraction device which moves from a constrained to relaxed configuration to immobilize and retract the dissected portion of target tissue during a dissection procedure.

Abstract: The present disclosure is directed to a medical instrument. The medical instrument may include a delivery device and a retraction mechanism including a target tissue anchor and a first stabilizing anchor, wherein the target tissue anchor attaches to target tissue and connects to the delivery device.

Abstract: A medical device comprising a syringe barrel, a plunger, and an injectable gel containing a coloring agent loaded in the syringe barrel. The injectable gel is sterilized by a sterilization process, such as an autoclaving process, while inside the syringe barrel. The injectable gel is adapted for injection between an upper mucosal layer and a lower layer at a target treatment site such that the upper mucosal layer separates from the lower layer and the upper mucosal layer is elevated. Also described herein are methods of forming the injectable gel.

Abstract: Medical devices and methods of using medical devices are disclosed. An example tissue retraction delivery device includes a positioning assembly, the assembly including: a delivery catheter having a distal end region and a lumen extending therein, wherein the distal end region includes an engagement member orienting tip. The delivery device also includes an actuation catheter extending within at least a portion of the delivery catheter, the actuation catheter including a distal end region and a lumen extending therein. An actuation wire extends within the lumen of the actuation catheter, the actuation wire having a proximal end region and a distal end region. An end effector is coupled to the distal end region of the actuation wire, the end effector configured to capture an engagement member of a tissue retraction device, wherein manipulation of the actuation wire shifts the end effector from a first position to a second closed position.

Abstract: A medical/surgical device for performing tissue resection can include an endoscope with proximal and distal ends, defining working channels, and a snare assembly located in one of the working channels. The working channel may include a bend near the distal end and towards the outward radial wall of the endoscope. The snare assembly may include a snare loop and an actuation element imparted with the pre-formed angular bends and an actuation control handle. The bends of the actuation element and the working channel may be the same. The rotational manipulation of the actuation element may synchronize the pre-formed bend of the actuation element with the bend of the working channel to concentrically (or otherwise) align the deployed snare loop with the endoscope or endoscope attachments.

Abstract: A medical device comprising a syringe barrel, a plunger, and an injectable viscous lifting agent containing a coloring agent loaded in the syringe barrel. The injectable viscous lifting agent is sterilized by a sterilization process, such as an autoclaving process, while inside the syringe barrel. The injectable viscous lifting agent is adapted for injection between an upper mucosal layer and a lower layer at a target treatment site such that the upper mucosal layer separates from the lower layer and the upper mucosal layer is elevated.

Abstract: A tissue closure device includes a needle and a suture extending therefrom, a proximal head including a proximal slot and a proximal locking mechanism for releasably engaging a first end of the needle in the proximal slot in a first configuration, and a distal head movably coupled to the proximal head so that the proximal and distal heads are movable relative to one another between an open configuration, in which a target tissue is received therebetween, and a closed configuration, in which the target tissue gripped therebetween. The distal head includes a distal slot and a distal locking mechanism for releasably engaging a second end of the needle in the distal slot in a second configuration, the needle movable between the first and second configurations by rotating the needle, the needle alternatingly passed between the proximal and distal heads to thread the suture through the target tissue.

Abstract: According to aspects of the present disclosure, a retrieval device may include a sheath, a first drive member in the sheath, and a second drive member in the sheath. The second drive member may be movable relative to the first drive member. An end effector may be retractable into and extendable out of the sheath. The end effector may include a first proximal end portion coupled to the first drive member, a second proximal end portion coupled to the second drive member, and a plurality of legs extending distally from the first and second proximal end portions to a distal tip of the end effector. All of the legs that extend to the distal tip may be fixed together at the distal tip.

Abstract: In one aspect of the present disclosure, a tissue retraction system may include a first anchor, a second anchor, and an elongate coupling member extending between the first anchor and the second anchor. The system also may include a holder for receiving the first anchor, the second anchor, and the elongate coupling element. The holder may include a proximal portion and a distal portion. The distal portion may have a smaller width than the proximal portion such that the distal portion exerts a force on a proximal end of the first anchor during deployment of the first anchor from the holder. The force may move the first anchor into an open configuration for receiving tissue.

Abstract: Medical systems are disclosed and may include an elongate member having a proximal end, a distal end, one or more channels extending between the proximal end and the distal end, and a handle operably coupled to the proximal end. The handle may include one or more ports in communication with the one or more channels. The medical systems may further include a docking station supporting the proximal end of the elongate member. The docking station may include a receiver adapted to receive and secure the handle and an adaptor guide unit having a distal end, a proximal end, and one or more passages formed therethrough, the one or more passages communicating with the one or more channels.

Abstract: A medical device may include a shaft, and a first tool extending from a distal end of the shaft. The medical device also may include a control assembly coupled to the shaft. The control assembly may include a console, a first grip extending proximally from the console, and a second grip extending proximally from the console. The control assembly also may include a first deflection actuator configured to deflect the first tool about a longitudinal axis of the first tool, a first rotation actuator configured to rotate the first tool about the longitudinal axis of the first tool, and a first longitudinal actuator configured to move the first tool along the longitudinal axis of the first tool.

Abstract: In one aspect of the present disclosure, a tissue retraction system may include a first anchor, a second anchor, and an elongate coupling member extending between the first anchor and the second anchor. The system also may include a holder for receiving the first anchor, the second anchor, and the elongate coupling element. The holder may include a proximal portion and a distal portion. The distal portion may have a smaller width than the proximal portion such that the distal portion exerts a force on a proximal end of the first anchor during deployment of the first anchor from the holder. The force may move the first anchor into an open configuration for receiving tissue.