Patents by Inventor Samuel V. AGRESTA

Samuel V. AGRESTA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION THERAPY FOR TREATING MALIGNANCIES
    Publication number: 20180303840
    Abstract: Provided are methods and compositions for treating cancers in patients carrying an IDH2 mutation using a combination of an inhibitor of a mutant IDH2 enzyme and a DNA demethylating agent.
    Type: Application
    Filed: October 14, 2016
    Publication date: October 25, 2018
    Inventors: Vivek Saroj Kumar Chopra, Jorge DiMartino, Laurie A. Kenvin, Robert Douglas Knight, Kyle MacBeth, Krishnan Viswanadhan, Qiang Xu, Samuel V. Agresta
  • Therapeutically active compounds and their methods of use
    Patent number: 10105369
    Abstract: Provided are compounds useful for treating cancer and methods of treating cancer, for example an advanced solid tumor, such as a glioma, or angioimmunoblastic T-cell lymphoma (AITL).
    Type: Grant
    Filed: January 8, 2018
    Date of Patent: October 23, 2018
    Assignee: Agios Pharmaceuticals, Inc.
    Inventor: Samuel V. Agresta
  • COMBINATION THERAPY FOR TREATING MALIGNANCIES
    Publication number: 20180296583
    Abstract: Provided are methods and compositions for treating cancers in patients carrying an IDH1 mutation using a combination of an inhibitor of a mutant IDH1 enzyme and a DNA demethylating agent.
    Type: Application
    Filed: October 14, 2016
    Publication date: October 18, 2018
    Inventors: Samuel V. Agresta, Krishnan Viswanadhan, Jorge DiMartino, Vivek Saroj Kumar Chopra, Kyle J. MacBeth, Robert Douglas Knight, Laurie Kenvin, Qiang Xu
  • Therapeutically active compounds and their methods of use
    Patent number: 10093654
    Abstract: Provided are compounds useful for treating cancer and methods of treating cancer, comprising administering to a subject in need thereof a compound described herein.
    Type: Grant
    Filed: July 13, 2017
    Date of Patent: October 9, 2018
    Assignee: Agios Pharmaceuticals, Inc.
    Inventors: Samuel V. Agresta, Chong-Hui Gu, David Schenkein, Hua Yang, Liting Guo, Zhen Tang, Jianming Wang, Yanfeng Zhang, Yan Zhou
  • THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE
    Publication number: 20180125850
    Abstract: Provided are compounds useful for treating cancer and methods of treating cancer, for example an advanced solid tumor, such as a glioma, or angioimmunoblastic T-cell lymphoma (AITL).
    Type: Application
    Filed: January 8, 2018
    Publication date: May 10, 2018
    Inventor: Samuel V. Agresta
  • Therapeutically active compounds and their methods of use
    Patent number: 9889137
    Abstract: Provided are compounds useful for treating cancer and methods of treating cancer, for example an advanced solid tumor, such as a glioma, or angioimmunoblastic T-cell lymphoma (AITL).
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: February 13, 2018
    Assignee: Agios Pharmaceuticals, Inc.
    Inventor: Samuel V. Agresta
  • THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE
    Publication number: 20170305885
    Abstract: Provided are compounds useful for treating cancer and methods of treating cancer, comprising administering to a subject in need thereof a compound described herein.
    Type: Application
    Filed: July 13, 2017
    Publication date: October 26, 2017
    Inventors: Samuel V. Agresta, Chong-Hui Gu, David Schenkein, Hua Yang, Liting Guo, Zhen Tang, Jianming Wang, Yanfeng Zhang, Yan Zhou
  • THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE
    Publication number: 20170266193
    Abstract: Provided are compounds useful for treating cancer and methods of treating cancer, for example an advanced solid tumor, such as a glioma, or angioimmunoblastic T-cell lymphoma (AITL).
    Type: Application
    Filed: June 2, 2017
    Publication date: September 21, 2017
    Inventor: Samuel V. Agresta
  • Therapeutically active compounds and their methods of use
    Patent number: 9738625
    Abstract: Provided are isocitrate dehydrogenase 2 (IDH2) inhibitor compounds useful for treating cancer and methods of treating cancer, comprising administering to a subject in need thereof a compound described herein. Also provided are polymorphic forms of the IDH2 inhibitor compounds characterized by X Ray powder diffraction patterns, having improved physicochemical properties that influence in vivo dissolution rate for formulation purposes.
    Type: Grant
    Filed: August 1, 2014
    Date of Patent: August 22, 2017
    Assignee: Agios Pharmaceuticals, Inc.
    Inventors: Samuel V. Agresta, Chong-Hui Gu, David Schenkein, Hua Yang, Liting Guo, Zhen Tang, Jianming Wang, Yanfeng Zhang, Yan Zhou
  • Therapeutically active compounds and their methods of use
    Patent number: 9694013
    Abstract: Provided are compounds useful for treating cancer and methods of treating cancer, for example an advanced solid tumor, such as a glioma, or angioimmunoblastic T-cell lymphoma (AITL).
    Type: Grant
    Filed: September 28, 2015
    Date of Patent: July 4, 2017
    Assignee: Agios Pharmaceuticals, Inc.
    Inventor: Samuel V. Agresta
  • THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE
    Publication number: 20160194305
    Abstract: Provided are isocitrate dehydrogenase 2 (IDH2) inhibitor compounds useful for treating cancer and methods of treating cancer, comprising administering to a subject in need thereof a compound described herein. Also provided are polymorphic forms of the IDH2 inhibitor compounds characterized by X Ray powder diffraction patterns, having improved physicochemical properties that influence in vivo dissolution rate for formulation purposes.
    Type: Application
    Filed: August 1, 2014
    Publication date: July 7, 2016
    Inventors: Samuel V. AGRESTA, Chong-Hui GU, David SCHENKEIN, Hua YANG, Liting GUO, Zhen TANG, Jianming WANG, Yanfeng ZHANG, Yan ZHOU
  • THERAPEUTICALLY ACTIVE COMPOUNDS AND THEIR METHODS OF USE
    Publication number: 20160089374
    Abstract: Provided are compounds useful for treating cancer and methods of treating cancer, for example an advanced solid tumor, such as a glioma, or angioimmunoblastic T-cell lymphoma (AITL).
    Type: Application
    Filed: September 28, 2015
    Publication date: March 31, 2016
    Inventor: Samuel V. AGRESTA