Patents by Inventor Samuil R. Umansky

Samuil R. Umansky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions containing lysophosphotidic acids which inhabit apoptosis and uses thereof
    Patent number: 7259273
    Abstract: The invention provides anti-apoptotic compositions containing lysophosphatidic acids and methods for making and using the compositions. Such compositions may also contain LPA potentiating agents, including proteins, lipid membrane structures and polymers such as polyethylene glycols. The compositions can additionally contain other pharmaceutically effective agents such as drugs, antibiotics, wound healing agents and antioxidants.
    Type: Grant
    Filed: September 26, 2005
    Date of Patent: August 21, 2007
    Inventors: John G. Goddard, Donald H. Picker, Samuil R. Umansky, Steven Price, Jac C. Wijkmans, Edward A. Boyd, Anthony D. Baxter
  • Methods for detection of nucleic acid sequences in urine
    Patent number: 6492144
    Abstract: Described are non-invasive methods of detecting the presence of specific nucleic acid sequences as well as nucleic acid modifications and alterations by analyzing urine samples for the presence of transrenal nucleic acids. More specifically, the present invention encompasses methods of detecting specific fetal nucleic acid sequences and fetal sequences that contained modified nucleotides by analyzing maternal urine for the presence of fetal nucleic acids. The invention further encompasses methods of detecting specific nucleic acid modifications for the diagnosis of diseases, such as cancer and pathogen infections, and detection of genetic predisposition to various diseases. The invention specifically encompasses methods of analyzing specific nucleic acid modifications for the monitoring of cancer treatment. The invention further encompasses methods of analyzing specific nucleic acids in urine to track the success of transplanted cells, tissues and organs.
    Type: Grant
    Filed: August 3, 2000
    Date of Patent: December 10, 2002
    Assignee: Diagen Corporation
    Inventors: Samuil R. Umansky, Anatoly V. Lichtenstein, Hovsep S. Melkonyan
  • Methods for detection of nucleic acid sequences in urine
    Publication number: 20020119478
    Abstract: Described are non-invasive methods of detecting the presence of specific nucleic acid sequences as well as nucleic acid modifications and alterations by analyzing urine samples for the presence of transrenal nucleic acids. More specifically, the present invention encompasses methods of detecting specific fetal nucleic acid sequences and fetal sequences that contained modified nucleotides by analyzing maternal urine for the presence of fetal nucleic acids. The invention further encompasses methods of detecting specific nucleic acid modifications for the diagnosis of diseases, such as cancer and pathogen infections, and detection of genetic predisposition to various diseases. The invention specifically encompasses methods of analyzing specific nucleic acid modifications for the monitoring of cancer treatment. The invention further encompasses methods of analyzing specific nucleic acids in urine to track the success of transplanted cells, tissues and organs.
    Type: Application
    Filed: November 7, 2001
    Publication date: August 29, 2002
    Applicant: Diagen Corporation
    Inventors: Samuil R. Umansky, Anatoly V. Lichtenstein, Hovsep S. Melkonyan
  • Methods for protection of nucleic acid sequences in urine
    Patent number: 6287820
    Abstract: Described are non-invasive methods of detecting and/or quantifying specific nucleic acid sequences by analyzing urine samples for nucleic acids that have crossed the kidney barrier. More specifically, the present invention encompasses methods of analyzing specific fetal nucleic acid sequences by analyzing maternal urine for the presence of fetal nucleic acids. The invention further encompasses methods of analyzing specific nucleic acid alterations for the diagnosis of disease. The invention encompasses methods of analyzing specific nucleic acid alterations for the diagnosis of cancer and the monitoring of its treatment. The invention further encompasses methods of analyzing specific nucleic acids in urine to track the success of transplanted cells, tissues and organs.
    Type: Grant
    Filed: July 3, 2000
    Date of Patent: September 11, 2001
    Assignee: Diagen Corporation
    Inventors: Samuil R. Umansky, Anatoly V. Lichtenstein, Hovsep S. Melkonyan
  • Methods for detection of nucleic acid sequences in urine
    Patent number: 6251638
    Abstract: Described are non-invasive methods of detecting the presence of specific nucleic acid sequences by analyzing urine samples for the presence of nucleic acids that have crossed the kidney barrier. More specifically, the present invention encompasses methods of detecting specific fetal nucleic acid sequences by analyzing maternal urine for the presence of fetal nucleic acids. The invention further encompasses methods of detecting specific nucleic acid alterations for the diagnosis of disease.
    Type: Grant
    Filed: February 4, 2000
    Date of Patent: June 26, 2001
    Assignee: Diagen Corporation
    Inventors: Samuil R. Umansky, Anatoly V. Lichtenstein, Hovsep S. Melkonyan