Abstract: Provided is a method of decreasing blood sugar level or preventing and/or treating a hyperglycemia-related disease, including administering an anti-Ang2 antibody or an antigen-biding fragment thereof to a subject in need thereof.

Abstract: Provided is a method of potentiating immunity or preventing or treating an immune-related disease comprising administering an anti-Ang2 antibody or an antigen-binding fragment thereof to a subject in need thereof.

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating a muscle wasting-related disease comprising diaminodiphenylsulfone (Dapsone; DDS) or a pharmaceutically acceptable salt thereof as an active ingredient. The composition according to the present invention may be effectively used to prevent or treat a muscle wasting-related disease by increasing muscle mass, preventing muscle loss and effectively restoring muscle function.

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating a muscle wasting-related disease comprising diaminodiphenylsulfone (Dapsone; DDS) or a pharmaceutically acceptable salt thereof as an active ingredient. The composition according to the present invention may be effectively used to prevent or treat a muscle wasting-related disease by increasing muscle mass, preventing muscle loss and effectively restoring muscle function.

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating a disease with bone mass loss, which comprises diaminodiphenylsulfone (Dapsone; DDS) or a pharmaceutically acceptable salt thereof as an active ingredient. The composition according to the present invention may be effectively used to prevent or treat a disease with bone mass loss such as osteopenia or osteoporosis by effectively restoring the reduction of bone density and bone mass.

Abstract: The present invention relates to a fluoride distillation apparatus and a method for quantifying sodium monofluorophosphate among fluorides using the same, which increases the acid resistance of the hard tissues of the teeth and promotes remineralization of initial caries lesion.

Abstract: A method of alarming an abnormal state of a line of an automated manufacturing system using a programmable logic controller (PLC) signal pattern is provided.

Abstract: Disclosed are a PLC (Programmable Logic Controller) symbol structure for a PLC code for automatically generating an input/output model, and a simulation apparatus and a simulation method for testing the PLC code using the same. In one embodiment, a computer-readable recording medium records a PLC code including a plurality of PLC symbols, wherein each of the PLC symbols includes a plurality of levels identified by an identifier, and a computer automatically generates an input/output model using the structure of each of the PLC symbols, thereby performing a simulation for testing the PLC code. The PLC symbol structure according to one embodiment systematically contains information required for automatically generating the input/output model, making it possible to automatically generate the input/output model for testing the PLC code in an easier manner without knowledge of simulation and modeling, and reducing the time consumed and the labor required for generating the input/output model.

Abstract: The present invention relates to a composition for the treatment and improvement of diabetes comprising caveolin as an active ingredient and a method for treating diabetes using the same, more precisely a composition comprising caveolin-1 as an active ingredient for the treatment and improvement of type II diabetes which is age-dependent but not showing obesity symptom and a method for treating diabetes using the same. The treatment method and composition of the present invention is very effective in improving and treating diabetes by regulating insulin sensitivity by increasing caveolin level in muscle tissues of type II diabetes patient which is age-dependent but not showing obesity symptom.

Abstract: An apparatus and method for distinguishing between tack-welding and welding are provided. The apparatus for distinguishing between tack-welding and welding includes: a current sensor configured to detect arc current of a welder; and a distinguish control unit configured to distinguish whether a welding operation performed by the welder is tack-welding or welding based on the arc current detected by the current sensor for a predefined period of time. Accordingly, the amount of work performed by a welding worker can be fairly and accurately evaluated.

Abstract: Provided are a system and a method for monitoring welding operations. The system includes a welding machine, a current sensor sensing an operation time of the welding machine and a welding current, a welding information database storing information of the operation time of the welding machine and the welding current for each welding operator and storing information of a consumed charge amount of the welding machine, which is preset for each welding operation process, a data analyzer checking a charge amount consumed for the operation time by using the sensed operation time of the welding machine and the welding current and determining whether the welding operator achieves a task goal of a corresponding process by comparing the checked consumed charge amount with the preset consumed charge amount for a process performed by the welding machine, and a display unit outputting a result of the determining, performed by the data analyzer, whether the welding operator achieves a task goal of a corresponding process.

Abstract: The present invention relates to a fluoride distillation apparatus and a method for quantifying sodium monofluorophosphate among fluorides using the same, which increases the acid resistance of the hard tissues of the teeth and promotes remineralization of initial caries lesion.

Abstract: The present invention relates to a composition for inhibiting cellular senescence, comprising N-[2-(cyclohexyloxyl)-4-nitrophenyl]-methanesulfonamide.

Abstract: The present invention relates to a pharmaceutical composition for promoting the healing of wounds, containing lysophosphatidic acid and an adenylyl cyclase inhibitor as active ingredients, and more particularly, to a pharmaceutical composition which contains an adenylyl cyclase inhibitor and which promotes the healing of wounds in senescent cells or aged persons having physiological characteristics different than those of young cells or young persons. In addition, the present invention relates to a method for promoting the healing of wounds involving treating a wounded person with an effective dose of the lysophosphatidic acid and adenylyl cyclase inhibitor.

Abstract: A clutch actuator assembly may include a motor provided with a rotatable worm shaft, a screw thread being formed at an exterior circumference of the worm shaft; a worm wheel having a disk shape, and provided with a worm gear engaged to the screw thread and first and second guiding holes; an operation unit mounted in the first and second guiding holes in order to move toward a radial direction of the worm wheel; and an upper body provided with a fork, and engaging or releasing a clutch by upward and downward movements of the fork corresponding to a movement of the operation unit.

Abstract: Disclosed are a PLC (Programmable Logic Controller) symbol structure for a PLC code for automatically generating an input/output model, and a simulation apparatus and a simulation method for testing the PLC code using the same. In one embodiment, a computer-readable recording medium records a PLC code including a plurality of PLC symbols, wherein each of the PLC symbols includes a plurality of levels identified by an identifier, and a computer automatically generates an input/output model using the structure of each of the PLC symbols, thereby performing a simulation for testing the PLC code. The PLC symbol structure according to one embodiment systematically contains information required for automatically generating the input/output model, making it possible to automatically generate the input/output model for testing the PLC code in an easier manner without knowledge of simulation and modeling, and reducing the time consumed and the labor required for generating the input/output model.

Abstract: A clutch actuator is configured to change operational force applied to a clutch in cases that a worm wheel is rotated by a motor. The clutch actuator may include a motor provided with a rotatable worm shaft, a screw thread formed along an exterior circumference of the worm shaft, a worm wheel provided with a worm gear engaging the screw thread, and a cam recess, an operation rod mounted to the worm wheel, the operation rod configured to engage or release a clutch, and a rotatable operation unit disposed within the cam recess, and configured to apply elastic force to the worm wheel. Methods of using the clutch actuator are also described.

Abstract: The present invention relates to a composition for controlling aging and/or extending lifespan. More specifically, the present invention relates to a composition containing dapsone as an effective component for controlling aging and/or extending lifespan, in which when applying the composition according to the present invention to an object, the effect of controlling aging or extending lifespan is excellent. Specifically, the treatment of dapsone (DDS) increases the lifespan of C. elegans not depending upon daf-16 and delays aging process, and reduces the activity of cytoplasmic dual oxidase 1 (Duox1) and mitochondria complex V protein. In addition, dapsone can maintain the low oxygen uptake rate in C. elegans thereby reducing ROS formation. In addition, ROS production by paraquat that is an inducing material of oxidative stress is reduced by treating dapsone and the sensitivity of paraquat is reduced.

Abstract: The present invention relates to a composition containing an extracellular matrix for controlling aging and a method for controlling aging by using the same. The composition for controlling aging and the method for controlling aging have an effect for recovering the biological function of the aged aging cell, and the amount of the expression of the integrin alpha V that is a cell membrane protein and is reduced if aging is again increased in the aging cell recovered by the young extracellular matrix. However, when the amount of expression of the integrin alpha V is artificially decreased by using siRNA and antibody, the aging cell is not recovered by the extracellular matrix extracted from the young cell.

Abstract: The present invention relates to the molecular mechanism inducing cell proliferation in aged human fibroblasts by inhibiting AMPK using LPA and AC inhibitor. Particularly, the present invention relates to a composition comprising LPA and ACI as active ingredients and the invention proves with the said composition that LPA and ACI regulate different phosphorylation of AMPK? and thus inactivate p53 and induce senescent cell proliferation. This results support the fact that AMPK signal transduction plays an important role in cell proliferation of senescent cells.