Abstract: A strain-insensitive heater, a method for manufacturing the strain-insensitive heater, and a wearable heating device including the same are disclosed. The strain-insensitive heater includes a substrate; a heating portion formed on the substrate; a first electrode formed on the substrate and contacting the heating portion; and a second electrode formed on the substrate and contacting the heating portion, wherein the second electrode is spaced apart from the first electrode, wherein the heating portion includes an array of vertically aligned carbon nanotubes (VACNTs) arranged horizontally on the substrate, wherein a longitudinal axis of each of the VACNTs is oriented in a perpendicular manner to a surface of the substrate.

Abstract: The present invention relates to a curved plasmonic metal nanostructure based on biomolecules and a nanoplasmonic biosensor using same.

Abstract: The present invention relates to metal nanoparticles and a plasmonic biosensor including the same. According to the present invention, it is possible to provide novel metal nanoparticles having significantly improved sensitivity to light, and further, it is possible to provide a plasmonic biosensor capable of detecting a trace amount of a biomarker present in a biological sample with high precision through the metal nanoparticles. In addition, the plasmonic biosensor is capable of detecting a sepsis biomarker with high sensitivity and specificity, and thus may be usefully used in various clinical applications such as sepsis diagnosis, identification of the type of organ dysfunction, prediction of sepsis severity, and post-treatment.

Abstract: A method for manufacturing a micro phase-change actuator, a micro phase-change actuator manufactured thereby, a method for manufacturing a micro phase-change actuator array, a micro phase-change actuator array manufactured thereby, and a tactile display including the same are disclosed. The method for manufacturing the micro phase-change actuator includes a first step of selectively forming a droplet of a phase-change material on a microheater formed on a substrate; a second step of freezing the droplet selectively formed on the microheater; and a third step of forming a stretchable membrane so as to seal at least the frozen droplet.

Abstract: The present invention relates to a high-sensitivity nanoplasmonic biosensor for detecting autophagy markers by plasmon resonance effect, a manufacturing method therefor, and an autophagy marker detection method using same. The nanoplasmonic biosensor according to the present invention can detect LC3, which is an autophagy marker, by using a plasmon resonance effect even without an additional marker, can perform detection at a low sensitivity and in a wide concentration range, and can quantify the concentration of a target protein on the basis thereof, and thus can be used for effectively measuring autophagy markers. Therefore, the nanoplasmonic biosensor according to the present invention can be variously used for: the detection of a complex mixture; the early detection of cancer; the early prevention of infections, neurological disorders and the like; and the like.

Abstract: The present invention relates to a bacteriophage-based gold nanohalo structure and a fabrication method therefor, and more particularly to a SERS-active gold nanohalo structure in which gold nanoparticles are regularly arranged on bacteriophage MS2, and a fabrication method therefor. The gold nanohalo structure according to the present invention may generate a consistent SERS signal due to regular arrangement of hot spots between the gold nanoparticles, and may be effectively used in the development of a SERS-based detection system.

Abstract: A photobioreactor fabrication system is disclosed. According to a first embodiment, the photobioreactor fabrication system includes a first unwinder 10 continuously unwinding a first transparent film 1, a second unwinder 20 arranged parallel to the first unwinder 10 and continuously unwinding a second transparent film 2 such that the second film 2 faces the first film 1, a heat sealer 30 pressurizing and heat sealing the first 1 and second films 2 to a baffle 3 arranged between the first 1 and second films 2 facing each other, and a rewinder 40 simultaneously and continuously winding the first 1 and second films 2 having passed through the heat sealer 30.

Abstract: Disclosed are a nanoplasmonic biosensor for detecting an autophagy marker with high sensitivity using a plasmon resonance effect, and a method of detecting an autophagy marker and a method of screening a cancer therapeutic agent using the same.

Abstract: Disclosed is a mutant strain having the ability to produce polyhydroxybutyrate. The novel strain has a significantly high growth rate and an improved ability to produce PHB compared to existing PHB-producing cyanobacterial strains. Therefore, the novel strain is suitable for use in the production of PHB and the development of various products using PHB. In addition, the novel strain is useful as a photosynthetic strain for developing a PHB production process using industrial flue gas due to its ability to produce PHB from only CO2 without any additional organic carbon source. Also disclosed is a method for producing polyhydroxybutyrate using the mutant strain.

Abstract: Disclosed are a surface-enhanced Raman scattering-based biosensor for diagnosing prostate cancer with high sensitivity and a method of detecting a prostate-cancer-derived target biomarker using the same.

Abstract: Disclosed are a metal nanostructure based on biomolecules and a nanoplasmonic biosensor using the same.

Abstract: The present invention relates to a nanoplasmonic biosensor capable of label-free multiplex detection of disease markers in blood with high selectivity and sensitivity and a method for detecting disease markers using the nanoplasmonic biosensor. The nanoplasmonic biosensor of the present invention enables label-free multiplex detection of miRNAs as disease markers in blood with high selectivity and sensitivity. Therefore, the nanoplasmonic biosensor of the present invention can be effectively used for the diagnosis of miRNA-related diseases and clinical applications.

Abstract: Disclosed is a method for culturing Haematococcus pluvialis containing a large amount of astaxanthin. According to one embodiment, the method includes culturing Haematococcus pluvialis under autotrophic conditions to prepare a culture containing cysts in which astaxanthin is accumulated and adding a nitrogen source to the culture to induce germination of the cysts.

Abstract: The present invention relates to: a single nanoparticle biosensor platform comprising a metal nanoparticle in which a biomolecule is immobilized between two metal nanoseeds, and a biosensor comprising same; a method for detecting mutations by using the biosensor; and a method for manufacturing a single nanoparticle biosensor platform, comprising a step of forming a metal nanoparticle in which a biomolecule is immobilized between two metal nanoseeds. The single nanoparticle biosensor platform according to the present invention enables high sensitivity and reliability detection of a target, and also enables direct identification of various mutations so as to enable the efficient diagnosis of mutations, thereby being widely usable in the biomedical diagnostic fields and the like.

Abstract: The present invention relates to a large-scale photosynthetic bioreactor in which transparent photobioreactors including a baffle are connected in parallel or in series by an adhesive element so that the reactor volume can be easily scaled up for scale-up culture of photosynthetic organisms, and to a fabrication method thereof. The large-scale photosynthetic bioreactor according to the present invention makes it possible to culture a larger amount of microalgae than a conventional photobioreactor in the same area. In addition, it has high light transmittance, produces a large amount of biomass per unit area due to smooth mixing, and has a significant effect of reducing carbon dioxide. Furthermore, the present invention has an advantage in that the number of photosynthetic bioreactors required to culture the same scale of photosynthetic organisms is significantly smaller than that in a conventional process for culture of photosynthetic organisms, and thus the operating costs can be reduced.

Abstract: Disclosed is a method for microalgal cultivation. The method includes cultivating a microalgal species in a medium in an autotrophic mode for a predetermined first time period where light is supplied and supplying an organic carbon source to the medium to cultivate the microalgal species in a heterotrophic mode for a predetermined second time period where the supply of light is stopped.

Abstract: Disclosed is a mutant strain having the ability to produce polyhydroxybutyrate. The novel strain has a significantly high growth rate and an improved ability to produce PHB compared to existing PHB-producing cyanobacterial strains. Therefore, the novel strain is suitable for use in the production of PHB and the development of various products using PHB. In addition, the novel strain is useful as a photosynthetic strain for developing a PHB production process using industrial flue gas due to its ability to produce PHB from only CO2 without any additional organic carbon source. Also disclosed is a method for producing polyhydroxybutyrate using the mutant strain.

Abstract: The present invention relates to a bacteriophage-based gold nanohalo structure and a fabrication method therefor, and more particularly to a SERS-active gold nanohalo structure in which gold nanoparticles are regularly arranged on bacteriophage MS2, and a fabrication method therefor. The gold nanohalo structure according to the present invention may generate a consistent SERS signal due to regular arrangement of hot spots between the gold nanoparticles, and may be effectively used in the development of a SERS-based detection system.

Abstract: A method for carbon resource utilization is disclosed. According to one embodiment, the method includes (a) supplying carbon dioxide to a medium to form bicarbonate ions (HCO3?) (S100), (b) inoculating one or more microalgal species into the medium, followed by photo-culture (S200), and (c) supplying calcium ions (Ca2+) to the medium, where the microalgal species are photo-cultured, to produce calcite (CaCO3)-containing biomass (S300).

Abstract: A method for carbon resource utilization is disclosed. According to one embodiment, the method includes (a) supplying carbon dioxide to a medium to form bicarbonate ions (HCO3?) (S100), (b) inoculating one or more microalgal species into the medium, followed by photo-culture (S200), and (c) supplying calcium ions (Ca2+) to the medium, where the microalgal species are photo-cultured, to produce calcite (CaCO3)-containing biomass (S300).