Abstract: According to the embodiment of the present disclosure, an organo tin compound is represented by the following Chemical Formula 1: In Chemical Formula 1, L1 and L2 are each independently selected from an alkoxy group having 1 to 10 carbon atoms and an alkylamino group having 1 to 10 carbon atoms, R1 is a substituted or unsubstituted aryl group having 6 to 8 carbon atoms, and R2 is selected from a substituted or unsubstituted linear alkyl group having 1 to 4 carbon atoms, a branched alkyl group having 3 to 4 carbon atoms, a cycloalkyl group having 3 to 6 carbon atoms, and an allyl group having 2 to 4 carbon atoms.

Abstract: An encryption key management method includes: receiving a data registration request from a supplier terminal, determining a data identifier associated with the content data, encrypting a master key with a public key of the supplier terminal, and providing the supplier terminal with the master key encrypted with the public key of the supplier terminal, the data identifier, and a key update count value; receiving a subscription application related to the data identifier from a first subscriber terminal, encrypting the master key with a public key of the first subscriber terminal, and providing the first subscriber terminal with the master key encrypted with the public key of the first subscriber terminal and the key update count value; receiving encrypted content data encrypted with the symmetric key and a hash for the content data from the supplier terminal; and transmitting the encrypted content data and the hash to the first subscriber terminal.

Abstract: Disclosed are a nanoplasmonic biosensor for detecting an autophagy marker with high sensitivity using a plasmon resonance effect, and a method of detecting an autophagy marker and a method of screening a cancer therapeutic agent using the same.

Abstract: Disclosed is a mutant strain having the ability to produce polyhydroxybutyrate. The novel strain has a significantly high growth rate and an improved ability to produce PHB compared to existing PHB-producing cyanobacterial strains. Therefore, the novel strain is suitable for use in the production of PHB and the development of various products using PHB. In addition, the novel strain is useful as a photosynthetic strain for developing a PHB production process using industrial flue gas due to its ability to produce PHB from only CO2 without any additional organic carbon source. Also disclosed is a method for producing polyhydroxybutyrate using the mutant strain.

Abstract: Disclosed are a surface-enhanced Raman scattering-based biosensor for diagnosing prostate cancer with high sensitivity and a method of detecting a prostate-cancer-derived target biomarker using the same.

Abstract: Disclosed are a metal nanostructure based on biomolecules and a nanoplasmonic biosensor using the same.

Abstract: The present invention relates to a nanoplasmonic biosensor capable of label-free multiplex detection of disease markers in blood with high selectivity and sensitivity and a method for detecting disease markers using the nanoplasmonic biosensor. The nanoplasmonic biosensor of the present invention enables label-free multiplex detection of miRNAs as disease markers in blood with high selectivity and sensitivity. Therefore, the nanoplasmonic biosensor of the present invention can be effectively used for the diagnosis of miRNA-related diseases and clinical applications.

Abstract: Disclosed is a method for culturing Haematococcus pluvialis containing a large amount of astaxanthin. According to one embodiment, the method includes culturing Haematococcus pluvialis under autotrophic conditions to prepare a culture containing cysts in which astaxanthin is accumulated and adding a nitrogen source to the culture to induce germination of the cysts.

Abstract: The present invention relates to: a single nanoparticle biosensor platform comprising a metal nanoparticle in which a biomolecule is immobilized between two metal nanoseeds, and a biosensor comprising same; a method for detecting mutations by using the biosensor; and a method for manufacturing a single nanoparticle biosensor platform, comprising a step of forming a metal nanoparticle in which a biomolecule is immobilized between two metal nanoseeds. The single nanoparticle biosensor platform according to the present invention enables high sensitivity and reliability detection of a target, and also enables direct identification of various mutations so as to enable the efficient diagnosis of mutations, thereby being widely usable in the biomedical diagnostic fields and the like.

Abstract: The present invention relates to a large-scale photosynthetic bioreactor in which transparent photobioreactors including a baffle are connected in parallel or in series by an adhesive element so that the reactor volume can be easily scaled up for scale-up culture of photosynthetic organisms, and to a fabrication method thereof. The large-scale photosynthetic bioreactor according to the present invention makes it possible to culture a larger amount of microalgae than a conventional photobioreactor in the same area. In addition, it has high light transmittance, produces a large amount of biomass per unit area due to smooth mixing, and has a significant effect of reducing carbon dioxide. Furthermore, the present invention has an advantage in that the number of photosynthetic bioreactors required to culture the same scale of photosynthetic organisms is significantly smaller than that in a conventional process for culture of photosynthetic organisms, and thus the operating costs can be reduced.

Abstract: Disclosed is a method for microalgal cultivation. The method includes cultivating a microalgal species in a medium in an autotrophic mode for a predetermined first time period where light is supplied and supplying an organic carbon source to the medium to cultivate the microalgal species in a heterotrophic mode for a predetermined second time period where the supply of light is stopped.

Abstract: Disclosed is a mutant strain having the ability to produce polyhydroxybutyrate. The novel strain has a significantly high growth rate and an improved ability to produce PHB compared to existing PHB-producing cyanobacterial strains. Therefore, the novel strain is suitable for use in the production of PHB and the development of various products using PHB. In addition, the novel strain is useful as a photosynthetic strain for developing a PHB production process using industrial flue gas due to its ability to produce PHB from only CO2 without any additional organic carbon source. Also disclosed is a method for producing polyhydroxybutyrate using the mutant strain.

Abstract: The present invention relates to a bacteriophage-based gold nanohalo structure and a fabrication method therefor, and more particularly to a SERS-active gold nanohalo structure in which gold nanoparticles are regularly arranged on bacteriophage MS2, and a fabrication method therefor. The gold nanohalo structure according to the present invention may generate a consistent SERS signal due to regular arrangement of hot spots between the gold nanoparticles, and may be effectively used in the development of a SERS-based detection system.

Abstract: A method for carbon resource utilization is disclosed. According to one embodiment, the method includes (a) supplying carbon dioxide to a medium to form bicarbonate ions (HCO3?) (S100), (b) inoculating one or more microalgal species into the medium, followed by photo-culture (S200), and (c) supplying calcium ions (Ca2+) to the medium, where the microalgal species are photo-cultured, to produce calcite (CaCO3)-containing biomass (S300).

Abstract: A method for carbon resource utilization is disclosed. According to one embodiment, the method includes (a) supplying carbon dioxide to a medium to form bicarbonate ions (HCO3?) (S100), (b) inoculating one or more microalgal species into the medium, followed by photo-culture (S200), and (c) supplying calcium ions (Ca2+) to the medium, where the microalgal species are photo-cultured, to produce calcite (CaCO3)-containing biomass (S300).

Abstract: The present invention relates to a nanoplasmonic biosensor capable of label-free multiplex detection of disease markers in blood with high selectivity and sensitivity and a method for detecting disease markers using the nanoplasmonic biosensor. The nanoplasmonic biosensor of the present invention enables label-free multiplex detection of miRNAs as disease markers in blood with high selectivity and sensitivity. Therefore, the nanoplasmonic biosensor of the present invention can be effectively used for the diagnosis of miRNA-related diseases and clinical applications.

Abstract: A method for screening an anticancer candidate is disclosed. The method includes immobilizing gold nanoparticles onto a substrate; binding a protein involved in carcinogenesis and metastasis to the immobilized gold nanoparticles, recording a spectrum of the protein conjugate, and analyzing the spectrum to obtain reference data; adding a candidate inhibiting the activity of the protein to the protein conjugate, recording a spectrum of the mixture, and analyzing the spectrum to obtain comparative data; and comparing the reference data with the comparative data to determine whether the candidate inhibits the activity of the protein. The method enables screening of a candidate inhibiting the activity of a protein involved in carcinogenesis and metastasis in an accurate and convenient manner.

Abstract: The present invention relates to a large-scale photosynthetic bioreactor in which transparent photobioreactors including a baffle are connected in parallel or in series by an adhesive element so that the reactor volume can be easily scaled up for scale-up culture of photosynthetic organisms, and to a fabrication method thereof. The large-scale photosynthetic bioreactor according to the present invention makes it possible to culture a larger amount of microalgae than a conventional photobioreactor in the same area. In addition, it has high light transmittance, produces a large amount of biomass per unit area due to smooth mixing, and has a significant effect of reducing carbon dioxide. Furthermore, the present invention has an advantage in that the number of photosynthetic bioreactors required to culture the same scale of photosynthetic organisms is significantly smaller than that in a conventional process for culture of photosynthetic organisms, and thus the operating costs can be reduced.

Abstract: The present invention relates to microalgae with improved phototaxis and photosynthetic efficiency, and more particularly, to a microalgae PTS42 (KCTC18499P) mutant of Chlamydomonas reinhardtii and uses thereof. In the microalgae PTS42 according to the present invention of which photosensitivity and photosynthetic efficiency are improved due to excellent phototaxis, conversion of carbon dioxide into biomass is excellent as compared to a wild type strain and a maximum photosynthesis rate and lipid accumulation ability are also high, such that the microalgae PTS42 are useful as a photosynthetic strain for constructing a biofuel production process as well as an effect of decreasing carbon dioxide.

Abstract: The present invention relates to a photobioreactor, and more particularly, a photobioreactor for culturing living organisms such as microalgae, which carry out photosynthesis using carbon dioxide and light energy. The photobioreactor includes: (a) a reaction vessel, in which photosynthesis occurs by photosynthetic organisms; (b) a multipurpose inlet/outlet formed at the outside upper end of the reaction vessel; (c) an outer pipe connected to the multipurpose inlet/outlet at the outside of the reaction vessel; and (d) an inner pipe connected to the multipurpose inlet/outlet at the inside of the reaction vessel, wherein the reaction vessel is made of a transparent film. The photobioreactor according to the present invention is advantageous in that the reaction vessel in which photosynthesis occurs is a plate-type and made of a transparent film, thus achieving improved light transmittance and mobility, and enabling the economically advantageous manufacture and operation thereof.