Patents by Inventor Sang Yup Lee

Sang Yup Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9423883
    Abstract: Provided are an electronic apparatus for determining validity of touch key input and a method and apparatus for determining validity of touch key input for the electronic apparatus. The method includes determining whether a touch key is input to perform a preset function, determining whether a dummy key used to determine validity of input of the touch key is input, if determining that the touch key is input, and determining validity of input of the touch key based on whether the dummy key is input. According to the present invention, by determining whether touch key input is intended by a user, it is possible to prevent a function undesired by the user from being performed.
    Type: Grant
    Filed: December 18, 2013
    Date of Patent: August 23, 2016
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Sang-Yup Lee, Hark-Sang Kim, Jung-Won Kim, Jong-Dae Park, Yeon-Hwan Kim, Hyong-Rae Cho
  • Patent number: 9410167
    Abstract: The present invention relates to cells or plants that can produce polylactate or its copolymers and to a method for preparing polylactate or its copolymers using the same. More specifically, cells or plants with the ability to produce polylactate or hydroxyalkanoate-lactate copolymers comprise both a gene encoding an enzyme that converts lactate into lactyl-CoA and a gene encoding polyhydroxyalkanoate (PHA) synthase which uses lactyl-CoA as a substrate. Also described is a method for preparing polylactate or hydroxyalkanoate-lactate copolymers which comprises culturing the cells in a medium containing lactate or lactate and various hydroxyalkanoates or culturing the plants. Effective preparation of hydroxyalkanoate-lactate copolymer which comprises various hydroxyalkanoates as well as polylactate, using the cells or the plants, is disclosed.
    Type: Grant
    Filed: May 24, 2006
    Date of Patent: August 9, 2016
    Assignees: LG CHEM, LTD., KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Jun-Hyeong Cho, Si-Jae Park, Sang-Yup Lee, Yu-Kyung Jung
  • Publication number: 20160216853
    Abstract: An electronic device is provided. The electronic device includes a display and a processor configured to control to display of the display one or more first objects related to a selected item if the item is selected by a first gesture from among one or more items displayed on the display, and control to display on the display one or more second objects for performing a function of a selected first object if the first object is selected by a second gesture continuing from the first gesture from among the one or more first objects.
    Type: Application
    Filed: January 22, 2016
    Publication date: July 28, 2016
    Inventor: Sang-Yup LEE
  • Patent number: 9388417
    Abstract: The present invention relates to a novel customized sRNA that reduces gene expression in prokaryotic cells, a preparation method thereof, and the use thereof, and more particularly to a synthetic sRNA comprising an Hfq binding site, derived from the sRNA of any one of MicC, SgrS and MicF, and a region that base-pairs with the target gene mRNA, and to a preparation method thereof and the use thereof. The synthetic sRNA according to the invention has an advantage in that the degree of inhibition of the target gene can be controlled by regulating the ability of the synthetic sRNA to bind to the mRNA of the target gene. The use of the synthetic sRNA that regulates the expression of the target gene makes it possible to effectively construct a recombinant microorganism without using a conventional gene deletion method and to reduce the expression of the target gene, and thus the synthetic sRNA is useful for the production of recombinant microorganisms.
    Type: Grant
    Filed: January 11, 2013
    Date of Patent: July 12, 2016
    Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sang Yup Lee, Dokyun Na, Seung Min Yoo
  • Publication number: 20160146739
    Abstract: The present invention relates to a hydrogel bead for detecting hydrofluoric acid and a kit comprising the same, and more particularly, to a hydrogel bead capable of detecting hydrofluoric acid using an organometallic ligand compound that reversibly changes color depending on the concentration of hydrofluoric acid when coming into contact with hydrofluoric acid, and to a kit for detecting hydrofluoric acid comprising the same. In an embodiment, a method for preparing a hydrogel bead for detecting hydrofluoric acid comprises the steps of: mixing an organic compound, which contains an aromatic functional group having at least one hydroxyl group bonded thereto, with a solution of a metal-ligand compound that bonds with the organic compound, thereby preparing a mixed solution; dropping the mixed solution onto a gelling agent; and adding coagulating agent to the mixture resulting from the dropping step to form a porous bead.
    Type: Application
    Filed: April 22, 2015
    Publication date: May 26, 2016
    Inventors: Sang Yup LEE, Chaemyeong LEE, Min Chul KIM, Jin Young KWAK, Sang Woo PARK, Young Jun LIM, Chang Joon KEUM
  • Patent number: 9322004
    Abstract: The present invention relates to a method of producing a fatty acid alkyl ester using microorganisms having the ability to produce oil, and more particularly to a method of producing a fatty acid alkyl ester, the method comprising culturing microorganisms having the ability to produce oil, thus accumulating a large amount of oil in the microorganisms, inducing the autolysis of the produced oil in the microorganisms to produce a free fatty acid, and converting the free fatty acid into an alkyl ester. According to the method of the present invention, oil accumulated in microorganisms, such as triacylglycerol that is typical oil produced by microorganisms, can be converted into a fatty acid alkyl ester with high efficiency using a metabolic engineering approach. Thus, the method of the present invention is useful for the industrial production of a fatty acid alkyl ester which has been recently found to be effective as biodiesel.
    Type: Grant
    Filed: July 19, 2010
    Date of Patent: April 26, 2016
    Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sang Yup Lee, Yong Jun Choi
  • Publication number: 20160083254
    Abstract: Disclosed is a method for enrichment of NF3 gas, comprising: (a) feeding a gas mixture containing a low concentration of NF3 gas and impurities; and (b) passing the feed gas mixture through a non-porous membrane module, wherein an enriched NF3 gas mixture passing through the non-porous membrane module and an unenriched NF3 gas mixture failing to pass through the non-porous membrane module are separated depending on the differences in the kinetic diameters of the individual gases.
    Type: Application
    Filed: September 17, 2015
    Publication date: March 24, 2016
    Inventors: Dong-Won LIM, Jong-Eun SHIN, Youn-Joong KIM, Hyun-Jun KIM, Sang-Yup LEE
  • Publication number: 20160017383
    Abstract: The present invention relates to a mutant microorganism, which is selected from the group consisting of genus Mannheimia, genus Actinobacillus and genus Anaerobiospirillum, producing homo-succinic acid and a method for producing homo-succinic acid using the same, and more particularly to a mutant microorganism producing succinic acid at a high concentration while producing little or no other organic acids in anaerobic conditions, which is obtained by disrupting a gene encoding lactate dehydrogenase (ldhA), a gene encoding phosphotransacetylase (pta), and a gene encoding acetate kinase (ackA), without disrupting a gene encoding pyruvate formate lyase (pfl), as well as a method for producing succinic acid using the same. The inventive mutant microorganism has the property of having a high growth rate and succinic acid productivity while producing little or no organic acids, as compared to the prior strains producing succinic acid.
    Type: Application
    Filed: October 3, 2015
    Publication date: January 21, 2016
    Applicant: Korea Advanced Institute of Science and Technology
    Inventors: Sang Yup Lee, Sung Won Lim, Hyohak Song
  • Patent number: 9217138
    Abstract: The present invention relates to a mutant microorganism, which is selected from the group consisting of genus Mannheimia, genus Actinobacillus and genus Anaerobiospirillum, producing homo-succinic acid and a method for producing homo-succinic acid using the same, and more particularly to a mutant microorganism producing succinic acid at a high concentration while producing little or no other organic acids in anaerobic conditions, which is obtained by disrupting a gene encoding lactate dehydrogenase (ldhA), a gene encoding phosphotransacetylase (pta), and a gene encoding acetate kinase (ackA), without disrupting a gene encoding pyruvate formate lyase (pfl), as well as a method for producing succinic acid using the same. The inventive mutant microorganism has the property of having a high growth rate and succinic acid productivity while producing little or no organic acids, as compared to the prior strains producing succinic acid.
    Type: Grant
    Filed: January 25, 2009
    Date of Patent: December 22, 2015
    Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sang Yup Lee, Sung Won Lim, Hyohak Song
  • Publication number: 20150362437
    Abstract: The present invention relates to a hydrogel, a preparation method thereof, and a pH sensor comprising the same, and more particularly, to a hydrogel, which can substitute for conventional pH paper, is continuously usable, can be used in various applications, and reversibly changes color depending on the pH of a sample, and to a pH sensor comprising the same. The hydrogel comprises: a polymer complex wherein a first organic compound containing an aromatic functional group having at least one hydroxyl group bonded thereto is joined to a carboxyl group-containing polysaccharide by a peptide bond; and an organic dye comprising a second organic compound containing an aromatic functional group having at least one hydroxyl group bonded thereto.
    Type: Application
    Filed: April 17, 2015
    Publication date: December 17, 2015
    Inventors: Sang Yup LEE, Chaemyeong LEE, Min Chul KIM, Jin Young KWAK, Sang Woo PARK, Young Jun LIM
  • Publication number: 20150353964
    Abstract: A mutant capable of producing 1,4-butanediol and a method of preparing 1,4-butanediol using the same are provided. The mutant microorganism is prepared by introducing and amplifying genes encoding enzymes converting succinate into 4-hydroxybutyrate and 4-hydroxybutyrate into 1,4-butanediol in a microorganism capable of producing succinate. The method includes culturing the mutant in a medium containing carbohydrate and obtaining 1,4-butanediol from the culture. Thus, 1,4-butanediol, which is essential in chemical industry, can be prepared in a biological process.
    Type: Application
    Filed: July 17, 2015
    Publication date: December 10, 2015
    Inventors: Si Jae PARK, Sang Hyun LEE, Sang Yup LEE, Eun Jeong LEE
  • Patent number: 9145583
    Abstract: A multi-spot metal-capped nanostructure array nucleic acid chip for diagnosing corneal dystrophy, and more particularly to a multi-spot metal-capped nanostructure array nucleic acid chip capable of employing LSPR (localized surface plasmon resonance) optical properties, a preparation method thereof, and a multi-spot metal-capped nanostructure array nucleic acid chip for diagnosing BIGH3 gene mutations, which can diagnose various corneal dystrophies. The metal-capped nanostructure array nucleic acid chip can be combined with analysis devices, including a light source, a detector, a spectrophotometer and a computer, to provide an LSPR optical property-based optical biosensor, and the use of the multi-spot metal-capped nanostructure array nucleic acid chip for diagnosing BIGH3 gene mutations allows the simultaneous diagnosis of various corneal dystrophies that are genetic ocular diseases.
    Type: Grant
    Filed: August 18, 2010
    Date of Patent: September 29, 2015
    Assignee: AVELLINO CO., LTD.
    Inventors: Sang Yup Lee, So Young Yoo, Do Kyun Kim, Tae Jung Park, Jung Kuk Yun, Gene Lee
  • Patent number: 9120891
    Abstract: Provided is a method of preparing polylactate (PLA) or a copolymer thereof using a mutant microorganism in which a gene participating in a coenzyme A (CoA) donor- and lactate-producing pathway is genetically manipulated to increase the productivity of a CoA donor and lactate. Amounts of the CoA donor and the lactate are simultaneously increased in a microbial metabolic pathway to enable effective biosynthesis of PLA and a hydroxyalkanoate-lactate copolymer having a high content of lactate, which is industrially useful.
    Type: Grant
    Filed: June 24, 2009
    Date of Patent: September 1, 2015
    Assignees: LG CHEM, LTD., KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sang Yup Lee, Yu Kyung Jung, Taek Ho Yang, Si Jae Park, Tae Wan Kim
  • Patent number: 9115362
    Abstract: The present invention relates to a mutant microorganism having a high ability to produce cadaverine, and a method for producing cadaverine using the same. More specifically, the invention relates to a mutant microorganism having a high ability to produce cadaverine wherein a gene involved in the cadaverine degradation or utilization pathway is inactivated or deleted, and to a method for producing cadaverine in high yield by culturing the mutant microorganism under aerobic conditions. The mutant microorganism according to the present invention is useful for producing a high yield of cadaverine which can be widely used in various industrial applications.
    Type: Grant
    Filed: August 3, 2011
    Date of Patent: August 25, 2015
    Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sang Yup Lee, Zhi Gang Qian, Xiaoxia Xia, Min Young Kim
  • Patent number: 9096860
    Abstract: A mutant capable of producing 1,4-butanediol and a method of preparing 1,4-butanediol using the same are provided. The mutant microorganism is prepared by introducing and amplifying genes encoding enzymes converting succinate into 4-hydroxybutyrate and 4-hydroxybutyrate into 1,4-butanediol in a microorganism capable of producing succinate. The method includes culturing the mutant in a medium containing carbohydrate and obtaining 1,4-butanediol from the culture. Thus, 1,4-butanediol, which is essential in chemical industry, can be prepared in a biological process.
    Type: Grant
    Filed: August 13, 2008
    Date of Patent: August 4, 2015
    Assignees: LG CHEM, LTD., KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Si-Jae Park, Sang-Hyun Lee, Sang-Yup Lee, Eun-Jeong Lee
  • Patent number: 9096872
    Abstract: The present invention relates to recombinant microorganisms having an increased ability to produce butanol, and a method of producing butanol using the same. More specifically, the invention relates to recombinant microorganisms whose ability to produce butanol was increased by manipulation of their metabolic networks, and a method of producing butanol using the same. The recombinant microorganisms having an increased ability to produce butanol comprise a deletion of a gene, which encodes an enzyme that converts acetyl CoA to acetate, in host microorganisms having genes that encode enzymes involved in acetyl CoA and butyryl CoA biosynthetic pathway. The recombinant microorganisms obtained by manipulating the metabolic flux of microorganisms are able to selectively produce butanol with high efficiency, and thus are useful as microorganisms for producing industrial solvents and transportation fuels.
    Type: Grant
    Filed: September 21, 2010
    Date of Patent: August 4, 2015
    Assignees: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY, BIOFUELCHEM CO., GS CALTEX CORPORATION
    Inventors: Sang Yup Lee, Yu-Sin Jang, Jin Young Lee, Joung Min Lee, Jin Hwan Park
  • Publication number: 20150193424
    Abstract: A method of changing a dynamic screen layout and an electronic device are provided. The method includes selecting at least two content items at least partially based on setting information associated with the content and characteristics of an application displaying the content, and providing the selected at least two content items. Furthermore, other embodiments can be made.
    Type: Application
    Filed: January 7, 2015
    Publication date: July 9, 2015
    Inventors: Sang-Yup LEE, Se-Jun SONG, Soon-Hyun CHA
  • Publication number: 20150151974
    Abstract: Method for preparing zinc-histidine self-assembly biomimetic complex activating reaction to convert carbon dioxide into bicarbonate ion, zinc-histidine self-assembly biomimetic complex by preparation method, and method for reducing carbon dioxide using zinc-histidine self-assembly biomimetic complex.
    Type: Application
    Filed: August 11, 2014
    Publication date: June 4, 2015
    Inventors: Sang-Yup LEE, Min-Chul KIM, Yu-Kyoung LEE, Sunhyung KIM, Jinyoung KWAK, Youngjoon LIM, Sangwoo PARK
  • Patent number: 8977530
    Abstract: Provided is a method for improving useful substance-producing organisms using metabolic flux analysis, and more particularly a method for improving a host organism producing a useful substance, the method including: calculating a maximum flux value corresponding to the theoretical maximum yield of the useful substance in the metabolic network model of the host organism for producing useful substance, and calculating the optimum value of metabolic flux associated with useful substance production in the metabolic network when the value of cell growth-associated metabolic flux is the maximum under the condition where fermentation data are applied or not applied; selecting metabolic fluxes whose absolute values increase from the range between the maximum value and the optimum value; screening genes associated with the selected metabolic fluxes; and introducing and/or amplifying the selected genes in the host organism. Production of the useful substance can be effectively improved by using the method.
    Type: Grant
    Filed: September 15, 2005
    Date of Patent: March 10, 2015
    Assignee: Korea Advanced Institute of Science and Technology
    Inventors: Sang Yup Lee, Han Min Woo, Hyung Seok Choi
  • Publication number: 20140377752
    Abstract: The present invention relates to a novel customized sRNA that reduces gene expression in prokaryotic cells, a preparation method thereof, and the use thereof, and more particularly to a synthetic sRNA comprising an Hfq binding site, derived from the sRNA of any one of MicC, SgrS and MicF, and a region that base-pairs with the target gene mRNA, and to a preparation method thereof and the use thereof. The synthetic sRNA according to the invention has an advantage in that the degree of inhibition of the target gene can be controlled by regulating the ability of the synthetic sRNA to bind to the mRNA of the target gene. The use of the synthetic sRNA that regulates the expression of the target gene makes it possible to effectively construct a recombinant microorganism without using a conventional gene deletion method and to reduce the expression of the target gene, and thus the synthetic sRNA is useful for the production of recombinant microorganisms.
    Type: Application
    Filed: January 11, 2013
    Publication date: December 25, 2014
    Inventors: Sang Yup Lee, Dokyun Na, Seung Min Yoo