Patents by Inventor Sang Yup Lee

Sang Yup Lee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210062232
    Abstract: The present disclosure relates to a mutant microorganism in which a glycerol catabolic pathway and a 1,3-PDO biosynthetic pathway are introduced into a microorganism incapable of using glycerol as a carbon source, and a method of producing 1,3-PDO using the same. According to the present disclosure, it is possible to produce 1,3-PDO while growing a mutant microorganism having 1,3-PDO production ability by using the inexpensive raw material glycerol as a single carbon source. Thus, the present disclosure is useful for the economical production of 1,3-PDO.
    Type: Application
    Filed: January 15, 2019
    Publication date: March 4, 2021
    Inventors: Sang Yup LEE, Jae Sung CHO, Je Woong KIM, Yoo Sung KO, Cindy Pricilia Surya PRABOWO, Taehee HAN, Euiduk KIM, Jae Won CHOI, Changhee CHO, Jun Kyu LEE
  • Publication number: 20210054375
    Abstract: The present disclosure relate to a composition for inhibiting a prokaryotic expression and a use thereof and, more specifically, to a composition for inhibiting an expression of Gram-positive bacteria, which includes an sRNA comprising an sRNA-derived Hfq binding site from prokaryotes and (ii) a region that forms a complementary bond with a target gene mRNA and an Hfq from prokaryotes, a method of producing same, and a use thereof. A synthetic sRNA according to the present disclosure and a composition comprising the sRNA for inhibiting a gene expression having an advantage of being able to control single and multiple target genes at a time, can effectively reduce the expression of the target gene without the conventional gene deletion process via the synthetic sRNA that controls a gene expression so as to be useful for the production of a recombinant microorganism, and are particularly useful for inhibiting a gene expression of Gram-positive bacteria.
    Type: Application
    Filed: March 8, 2019
    Publication date: February 25, 2021
    Inventors: Sang Yup LEE, Dongsoo YANG, Jae Sung CHO
  • Patent number: 10851390
    Abstract: The present invention relates to a method of producing metal nanoparticles and metal sulfide nanoparticles using a recombinant microorganism co-expressing metallothionein and phytochelatin synthase, which are heavy metal-adsorbing proteins, and to the use of metal nanoparticles and metal sulfide nanoparticles synthesized by the method. The present invention provides a method for synthesizing metal nanoparticles which have been difficult to synthesize by conventional biological methods. The present invention makes it possible to synthesize metal nanoparticles in an environmentally friendly and cost-effective manner, and also makes it possible to synthesize metal sulfide nanoparticles. In addition, even metal nanoparticles which could have been produced by conventional chemical or biological methods are produced in a significantly increased yield by use of the method of the present invention.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: December 1, 2020
    Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sang Yup Lee, Yoojin Choi
  • Patent number: 10837005
    Abstract: Disclosed are a recombinant microorganism capable of producing methyl anthranilate, wherein the recombinant microorganism is obtained by introducing an aamt1 gene into a microorganism having the capacity to produce anthranilic acid (ANT), and a method of producing methyl anthranilate using the same. The recombinant microorganism is capable of producing methyl anthranilate using only a purely biological process from renewable carbon-circulating biomass without chemical catalytic reaction, thus having an advantage of enabling mass production of high value-added methyl anthranilate in a very economical manner based on an environmentally friendly and simple production process.
    Type: Grant
    Filed: February 15, 2020
    Date of Patent: November 17, 2020
    Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sang Yup Lee, Zi Wei Luo, Jae Sung Cho
  • Patent number: 10831362
    Abstract: A mobile terminal and a method of supporting an object change for the same are provided. The mobile terminal includes a display unit for outputting at least one object, and a control unit for controlling at least one of directly displaying, in response to a signal for changing the output object into a second object having a similar function but being of a different type than the output object, the second object on the display unit without a screen transition, and for outputting, in response to a signal for changing the output object into a second object having a similar function but being of a different type than the output object, a guide frame on the display unit so as to facilitate change of the output object without a screen transition.
    Type: Grant
    Filed: August 17, 2018
    Date of Patent: November 10, 2020
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Nam Jo Heo, Sang Yup Lee, Yong Seok Kim, Kwang Sub Son
  • Publication number: 20200270587
    Abstract: Disclosed are a recombinant microorganism capable of producing methyl anthranilate, wherein the recombinant microorganism is obtained by introducing an aamt1 gene into a microorganism having the capacity to produce anthranilic acid (ANT), and a method of producing methyl anthranilate using the same. The recombinant microorganism is capable of producing methyl anthranilate using only a purely biological process from renewable carbon-circulating biomass without chemical catalytic reaction, thus having an advantage of enabling mass production of high value-added methyl anthranilate in a very economical manner based on an environmentally friendly and simple production process.
    Type: Application
    Filed: February 15, 2020
    Publication date: August 27, 2020
    Inventors: Sang Yup LEE, Zi Wei LUO, Jae Sung CHO
  • Publication number: 20200261823
    Abstract: The present invention relates to a process for energy recovery in a process for the preparation of 1,3,5-trioxane.
    Type: Application
    Filed: December 7, 2016
    Publication date: August 20, 2020
    Inventors: Achim STAMMER, Thomas HEITZ, Marvin KRAMP, Jong-Moon KIM, In-Gi CHO, Jin-Sang CHOI, Sang-Yup LEE
  • Patent number: 10683512
    Abstract: The present disclosure relates to a recombinant microorganism having a lactam production capacity from an omega-amino acid, into which a gene encoding a beta-alanine coenzyme A transferase on a microorganism which has an omega-amino acid biosynthetic metabolic pathway inherently or an omega-amino acid biosynthetic metabolic pathway is introduced, and a method for producing a variety of lactams and omega-amino acyl-CoAs using the same. The recombinant microorganism and the method for producing the lactam according to the present disclosure are useful in producing a variety of lactams such as propiolactam, 2-pyrrolidone, valerolactam, caprolactam, and heptanolactam from a variety of omega-amino acids.
    Type: Grant
    Filed: April 11, 2016
    Date of Patent: June 16, 2020
    Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sang Yup Lee, Tong Un Chae, Chan Woo Song
  • Patent number: 10684650
    Abstract: An electronic device is provided. The electronic device includes a housing including a first plate, a second plate facing away from the first plate, and a side member surrounding a space between the first plate and the second plate, a touch screen display disposed between the first plate and the second plate, a fingerprint sensor, a digitizer including a layer having a conductive pattern, and a processor. The layer includes a first portion positioned between the second plate and a second area of the touch screen display that surrounds the first area when viewed from above the first plate and a second portion continuously extending from the first portion, the second portion positioned such that the fingerprint sensor is disposed between the second portion and the touch screen display, and such that the second portion is closer to the second plate than the first portion.
    Type: Grant
    Filed: May 24, 2018
    Date of Patent: June 16, 2020
    Assignee: Samsung Electronics Co., Ltd
    Inventors: Young Bae Sim, Hyun Suk Choi, Do Yeong Kim, Min Chul Kim, Sang Yup Lee, Sung Yoon Jung, Jin Woo Park, Ji Woo Lee, Yeun Wook Lim
  • Patent number: 10640774
    Abstract: The present invention relates to a recombinant microorganism having the ability to produce poly(lactate-co-glycolate) and its copolymers from xylose, and more particularly to a recombinant microorganism having the ability to produce poly(lactate-co-glycolate) and its copolymers without having to supply a glycolate precursor from an external source, and a method of producing a poly(lactate-co-glycolate) copolymers using the same.
    Type: Grant
    Filed: December 13, 2016
    Date of Patent: May 5, 2020
    Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sang Yup Lee, So Young Choi, Si Jae Park
  • Publication number: 20190382817
    Abstract: The present invention relates to a microorganism variant having the ability to extracellularly produce heme, and more particularly to a metabolically engineered microorganism variant having the ability to extracellularly produce heme and a method of producing heme using the same. According to the present invention, heme, an organometallic compound which is increasingly used as a health food or food supplement for the treatment of porphyria, can be extracellularly secreted and produced in high yield using the microorganism variant, but not conventional chemical synthesis or enzymatic synthesis.
    Type: Application
    Filed: December 12, 2018
    Publication date: December 19, 2019
    Inventors: Sang Yup LEE, Xin Rui ZHAO, Kyeong Rok CHOI
  • Publication number: 20190352622
    Abstract: The present invention relates to a recombinant microorganism to which a gene coding for 2-hydroxyisocaproate-CoA transferase and a gene coding for polyhydroxyalkanoate synthase are introduced and which has a potential of producing polyhydroxyalkanoate bearing an aromatic monomer or a long-chain 2-HA monomer and a method for producing polyhydroxyalkanoate bearing an aromatic monomer or a long-chain 2-HA monomer, using the recombinant microorganism. According to the present invention, a biodegradable polymer bearing an aromatic monomer or a long-chain 2-HA monomer can be produced.
    Type: Application
    Filed: February 26, 2018
    Publication date: November 21, 2019
    Inventors: Sang Yup LEE, Jung Eun YANG, Si Jae PARK
  • Patent number: 10472636
    Abstract: The present invention relates to a mutant organism having the ability to produce aspartic acid derivatives, wherein a gene encoding the glyoxylate shunt regulator and a gene encoding fumarase are deleted and a gene encoding aspartase is overexpressed compared to that in a wild-type strain, and to a method for producing L-aspartic acid derivatives using the same. According to the present invention, various aspartic acid derivatives, including L-alanine, 3-aminopropionic acid, threonine, 1,3-diaminopropane, lysine, methionine, 3-hydroxypropionic acid, cadaverine, 5-aminovaleric acid, etc., can be produced by biological methods.
    Type: Grant
    Filed: March 17, 2016
    Date of Patent: November 12, 2019
    Assignee: KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sang Yup Lee, Tong Un Chae, Chan Woo Song
  • Publication number: 20190338316
    Abstract: The present invention relates to a recombinant microorganism having heterologous genes introduced thereto and a method for producing a useful material from formic acid and carbon dioxide using the microorganism. The present invention provides a novel microorganism having a cyclic metabolic pathway introduced thereto through which C3 or higher carbon organic compounds can be synthesized from formic acid and carbon dioxide, whereby carbon dioxide rich in nature and formic acid that is of low toxicity and suitable for anabolic reaction in view of reaction kinetics and which can be easily and rapidly synthesized from carbon dioxide can be used to effectively synthesize the C3 organic compound pyruvic acid from which various high-value added compound can be synthesized.
    Type: Application
    Filed: November 20, 2017
    Publication date: November 7, 2019
    Inventors: Sang Yup LEE, Junho BANG
  • Patent number: 10402050
    Abstract: An electronic device is provided. The electronic device includes a display and a processor configured to control to display of the display one or more first objects related to a selected item if the item is selected by a first gesture from among one or more items displayed on the display, and control to display on the display one or more second objects for performing a function of a selected first object if the first object is selected by a second gesture continuing from the first gesture from among the one or more first objects.
    Type: Grant
    Filed: January 22, 2016
    Date of Patent: September 3, 2019
    Assignee: Samsung Electronics Co., Ltd.
    Inventor: Sang-Yup Lee
  • Patent number: 10360719
    Abstract: Provided are a high-quality texture obtaining apparatus and a high-quality texture obtaining method. The high-quality texture obtaining apparatus includes a stereoscopic information obtainer configured to obtain a stereoscopic model of an object onto which patterns have been projected and a first texture map including information about a texture and color of the object, from an image obtained by photographing the object; a virtual pattern projector configured to project virtual pattern light onto the stereoscopic model to project a virtual pattern onto the stereoscopic model; a texture map obtainer configured to extract a second texture map including information about a texture and a color of the stereoscopic model onto which the virtual pattern light has been projected; and a pattern remover configured to remove the patterns from the first texture map by referring to the second texture map and obtain a third texture map from which the patterns have been removed.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: July 23, 2019
    Assignee: Flux Planet, Inc.
    Inventor: Sang Yup Lee
  • Patent number: 10351890
    Abstract: The present invention relates to a method for improving the production of a difficult-to-express recombinant protein in a recombinant microorganism, and more particularly to a method for improving the production of a difficult-to-express recombinant protein by use of a recombinant microorganism into which a gene encoding a target protein and an sRNA against a gene encoding ribonuclease P are introduced. According to the present invention, expressions of a large recombinant protein, a difficult-to-express protein and a useful protein can be dramatically increased by reducing expression of the rnpA gene.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: July 16, 2019
    Assignee: MEDICOSBIOTECH, INC.
    Inventors: Sang Yup Lee, Hannah Chung
  • Patent number: 10288569
    Abstract: A method for preparing a hydrogel that reversibly changes color depending on pH includes: (S10) dissolving a carboxyl group-containing polysaccharide in buffer to obtain a polysaccharide solution; (S20) adding a cross-linker solution composed of a mixture of an organic solvent and a cross-linker to the polysaccharide solution; (S30) adding, to the cross-linker-containing polysaccharide solution resulting from step (S20), an organic solution composed of a mixture of an organic solvent and a first organic compound containing an aromatic functional group having at least one hydroxyl group bonded thereto, to form a mixture solution, and allowing the mixture solution to react; (S40) obtaining a polymer complex from the reaction mixture resulting from step (S30); and (S50) mixing the polymer complex from step (S40) with an organic dye comprising a second organic compound containing an aromatic functional group having at least one hydroxyl group bonded thereto.
    Type: Grant
    Filed: February 8, 2017
    Date of Patent: May 14, 2019
    Assignee: INDUSTRY-ACADEMIC CORPORATION FOUNDATION YONSEI UNIVERSITY
    Inventors: Sang Yup Lee, Chaemyeong Lee, Min Chul Kim, Jin Young Kwak, Sang Woo Park, Young Jun Lim
  • Publication number: 20190056836
    Abstract: According to an embodiment, a method for operating an electronic device may comprise operating touch circuitry configured to detect a touch or hovering according to a first driving signal in a first operation mode, detecting a first event related to mode switching, and operating the touch circuitry according to a second driving signal different from the first driving signal in a second operation mode based on detecting the first event. Other embodiments are also possible.
    Type: Application
    Filed: August 17, 2018
    Publication date: February 21, 2019
    Inventors: Sang-Yup LEE, Tae-Kyoung KANG, Yeon-Hwan KIM, Jun-Ho KO, Young-Jun AN, Won-Woo YOO, Ji-Young LIM, Jang-Hoon HONG, Hyun-Suk CHOI
  • Patent number: D842780
    Type: Grant
    Filed: March 1, 2016
    Date of Patent: March 12, 2019
    Assignee: Bentley Motors Ltd.
    Inventors: Sang Yup Lee, Luc Donckerwolke