Abstract: Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and an immunomodulatory agent (e.g. an agent directed to ICOS or an anti-CD38 antigen binding protein).

Abstract: A semiconductor device fabrication process includes forming gates on a substrate having a plurality of openings, each gate having a conducting layer a first metal and a gate dielectric layer of a first dielectric material, partially filling the openings with a second dielectric material, forming a first structure on the substrate in a processing system without breaking vacuum, depositing a third dielectric material over the first structure, and forming a planarized surface of the gates and a surface of the third dielectric material that is disposed over the first structure. The forming of the first structure includes forming trenches by removing second portions of the second dielectric material within each opening, forming recessed active regions in the trenches by partially filling the trenches with a second metal, forming a liner over each recessed active region, and forming a metal cap layer over each liner.

Abstract: Methods and systems for visualization of mobile terminal communication link status are disclosed. In some aspects, one or more mobile terminal icons are provided for display on a map of a geographic area at map locations representing geographic locations of the mobile terminals. Coverage area icons of one or more network services are also displayed on the map. Features of the mobile terminal and coverage area icons indicate a network status of the respective terminals and coverage areas. In some aspects, prior location icons representing prior locations of the mobile terminal(s) are displayed on the map. In some of these aspects, clicking or hovering on the prior location icons provides for display, link performance data when the corresponding mobile terminal was at the geographic location represented by the prior location icon.

Abstract: Methods and compositions for the treatment of treatment-resistant depression are described. More specifically, the invention demonstrates that intranasal administration of ketamine is effective to ameliorate the symptoms of depression in a patient who has not responded to an adequate trial of one antidepressant in the current episode and has recurrent or chronic depressive symptoms (>2 years).

Abstract: A system and method improve the performance of non-volatile memory storage by rebuilding, on the fly, “lost data” in response to a read request, which identifies data to be read or recovered, by identifying a parity data storage device in a set of data storage devices that contains parity corresponding to the identified data; sending a reconstruction request to a respective data storage device, which may be the parity data storage device or other data storage device in the system, to reconstruct the identified data, and receiving the identified data from the respective data storage device. The reconstruction request commands the respective data storage device to retrieve, via peer-to-peer read requests, from other data storage devices, data from one or more data blocks, and to reconstruct the identified data based on the retrieved data and parity data locally stored at the parity data storage device.

Abstract: Disclosed herein is a method of treating cancer, such as multiple myeloma, involving the combination of an anti-BCMA antigen binding protein (e.g., an anti-BCMA antibody) and an immunomodulatory drug (e.g. pomalidomide or lenalidomide). The combinations can also include an anti-inflammatory compound (e.g. dexamethasone).

Abstract: Control systems and feedback assemblies for hydraulic axial displacement machines, such as pumps and motors. The control systems and feedback assemblies can reduce friction on the charging spools and provide for a more reliable return of the swashplate to a neutral position. Aspects of the control systems and feedback assemblies can be modularized for, e.g., easy maintenance and to reduce the overall size of the system.

Abstract: The present disclosure generally relates to methods for forming a semiconductor device, a semiconductor device, and a processing chamber. The method includes forming a source/drain region in a processing system, forming a doped semiconductor layer on the source/drain region in the processing system, forming a metal silicide layer, forming a dielectric material, forming a trench in the dielectric material, and filling the trench with a conductor. The source/drain region, the doped semiconductor layer, and the metal silicide layer are formed without breaking vacuum. A semiconductor device includes a plurality of layers, and the semiconductor device has reduced contact resistance. A processing system is configured to perform the method and form the semiconductor device.

Abstract: There is a need for solutions that perform preprocessing and/or searching of documents with semantic intelligence. This need can be addressed by, for example, by performing pre-processing of each document of a plurality of documents to generate an indexed representation for the document by identifying sentences in the document; determining, for each n-gram of one or more n-grams associated with the document, one or more n-gram semantic scores based semantic proximity indicators for the n-gram; determining, based at least in part on each one or more n-gram semantic scores, one or more sentence semantic labels for each sentence in the document; and determining the indexed representation for the document based at least in part on the one or more sentence semantic labels for the document; performing the search query based each indexed representation associated with a document; and transmitting the result to a computing device associated with the search query.

Abstract: A device and methodology for concomitant ejection and suction of a perfusate (CESOP) within a region of interest without spillover of the perfusate to a juxtaposed anatomical region. An inflow line, connected to a perfusate cistern, is coupled to an outflow line, connected to outflow control mechanisms, via an elongate rigid support. Perfusate can flow through the inflow line to the region of interest, and nearly simultaneously, the outflow line can suction the perfusate out of the region of interest. The amount of time that the perfusate remains in the region of interest is sufficient to take effect in the region of interest. The rigid support helps control the inflow and outflow lines. A micromanipulator can also be used to control the lines and application tip thereof. Either or both lines may also have adjustable flow rates therethrough and may include stoppers/regulators.

Abstract: A method of accessing data includes storing a table that includes a plurality of tablets corresponding to distinct non-overlapping table portions. Respective pluralities of tablet access objects and application objects are stored in a plurality of servers. A distinct application object and distinct tablet are associated with each tablet access object. Each application object corresponds to a distinct instantiation of an application associated with the table. The tablet access objects and associated application objects are redistributed among the servers in accordance with a first load-balancing criterion. A first request directed to a respective tablet is received from a client. In response, the tablet access object associated with the respective tablet is used to perform a data access operation on the respective tablet, and the application object associated with the respective tablet is used to perform an additional computational operation to produce a result to be returned to the client.

Abstract: A more efficient network can be achieved by leveraging an adaptive dejitter buffer. The dejitter buffer can be dynamically adjusted based off a network data analysis. A communication handover can be adjusted or shifted based on voice inactivity data related to a forecasted punctuation. The dejitter buffer memory/depth of a mobile device can also be adjusted in accordance with receiving a delay interruption length associated with another mobile device. Thereafter, the dejitter buffer memory can be filled with voice packet data to decrease a packet delay variation at the mobile device.

Abstract: Technical solutions are described for visually depicting health of a cognitive system. An example computer-implemented method includes accessing a query-log of a question input to the cognitive system. The method also includes generating a query-node corresponding to the question. The method also includes configuring animation parameters of the query-node based on the query-log. The method also includes displaying the query-node according to the animation parameters.

Abstract: Multi-chip systems and structures for modular scaling are described. In some embodiments an interfacing bar is utilized to couple adjacent chips. For example, a communication bar may utilized to coupled logic chips, and memory bar may be utilized to couple multiple memory chips to a logic chip.

Abstract: Disclosed are compounds which are nuclear receptor modulators that can act as antagonists to the androgen receptor, for example, a compound of Formula I: wherein R1 to R5 and X1 to X5 are as described herein, as well as pharmaceutically acceptable salts, solvates, and stereoisomers thereof. Pharmaceutical compositions comprising such compounds, as well as methods of use, and treatment for cancers, including prostate cancers, other nuclear receptor mediated cancers, and other conditions, are also disclosed.

Abstract: Some embodiments include an apparatus including a first node to receive an input data signal including a first edge, and a second edge occurring after the first edge; a second node to receive a strobe signal including an edge; a first circuit to generate a modified strobe signal based on the strobe signal, the modified strobe signal including an edge occurring after the edge of the strobe signal; a second circuit to generate a modified data signal based on the input data signal, the modified data signal including an edge occurring after the second edge of the input data signal; and a third circuit to respond to the modified strobe signal and generate an output data signal based on the modified data signal.

Abstract: Embodiments described herein relate to gas line systems with a multichannel splitter spool. In these embodiments, the gas line systems will include a first gas line that is configured to supply a first gas. The first gas line is coupled to a multichannel splitter spool with a plurality of second gas lines into which the first gas flows. Each gas line of the plurality of second gas lines will have a smaller volume than the volume of the first gas line. The smaller second gas lines will be wrapped by a heater jacket. Due to the smaller volume of the second gas lines, when the first gas is flowed through the second gas lines, the heater jacket will sufficiently heat the first gas, eliminating the condensation induced particle defects that occur in conventional gas line systems when the first gas meets with a second gas in the gas line system.

Abstract: The present disclosure is directed to augmented reality navigation systems and methods of their use that, inter alia, address the need for systems and methods of robotic surgical system navigation with reduced distraction to surgeons. Augmented reality navigation systems disclosed herein enable a surgeon to maintain focus on a surgical site and/or surgical tool being used in a surgical procedure while obtaining a wide range of navigational information relevant to the procedure. Navigational information can appear in the augmented reality navigation system as being presented on virtual displays that sit in a natural field of view of a surgeon during a procedure. Navigational information can also appear to be overlaid over a patient's anatomy. Augmented reality navigation systems comprise a head mounted display comprising an at least partially transparent display screen, at least one detector connected to the head mounted display for identifying real-world features, and a computer subsystem.

Abstract: Control systems and feedback assemblies for hydraulic axial displacement machines, such as pumps and motors. The control systems and feedback assemblies can have enhanced adjustability.

Abstract: A device may obtain information identifying a base application. The device may extract a set of sub-application artifacts associated with the base application based on structural information associated with the base application. The device may define a set of metadata attributes associated with the set of sub-application artifacts associated with the base application. The device may generate a set of hash tuples for the set of metadata attributes associated with the set of sub-application artifacts associated with the base application. The device may generate a base composite identity of the base application based on the set of hash tuples. The device may store the base composite identity in a blockchain and in connection with storage of the base application in the blockchain to enable subsequent identification and verification of the base application.