Patents by Inventor Santiago Ini

Santiago Ini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pure duloxetine hydrochloride
    Publication number: 20060270731
    Abstract: Chemically and/or enantiomerically pure duloxetine HCl and process for preparing chemically and/or enantiomerically pure duloxetine HCl are provided.
    Type: Application
    Filed: March 14, 2006
    Publication date: November 30, 2006
    Inventors: Santiago Ini, Mili Abramov, Anita Liberman
  • Process for the preparation of optically active (S)-(+)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine
    Publication number: 20060270861
    Abstract: Diasteromerically enriched salts of (S)-DNTH+ EPA? and (R)-DNTH+EPA?, methods of preparing such diasteromerically enriched salts of (S)-DNTH+ EPA? and (R)-DNTH+ EPA?, and methods of preparing enantiomerically enriched (S)-DNT and enantiomerically enriched (R)-DNT are provided.
    Type: Application
    Filed: March 14, 2006
    Publication date: November 30, 2006
    Inventors: Santiago Ini, Mili Abramov, Anita Liberman
  • Duloxetine HCl polymorphs
    Publication number: 20060270859
    Abstract: A crystalline form of duloxetine hydrochloride, pharmaceutical compositions of the crystalline form of duloxetine hydrochloride, and methods of preparing the crystalline form of duloxetine hydrochloride are provided.
    Type: Application
    Filed: January 27, 2006
    Publication date: November 30, 2006
    Inventors: Santiago Ini, Yaron Shmuel, Tamas Koltai, Amir Gold
  • Crystal forms of (S)-(+)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine oxalate and the preparation thereof
    Publication number: 20060270860
    Abstract: DNT-Oxal crystalline forms and processes for making DNT-Oxal crystalline forms are provided.
    Type: Application
    Filed: March 8, 2006
    Publication date: November 30, 2006
    Inventors: Santiago Ini, Anita Liberman, Tamas Koltai
  • Amorphous tegaserod maleate
    Publication number: 20060258633
    Abstract: Provided are amorphous and purely amorphous tegaserod maleate and processes for the preparation thereof. Also provided are pharmaceutical compositions comprising amorphous or purely amorphous tegaserod maleate and methods for the treatment of irritable bowel syndrome using the same.
    Type: Application
    Filed: March 8, 2006
    Publication date: November 16, 2006
    Inventors: Santiago Ini, Michael Pinchasov, Tamas Koltai, Judith Aronhime
  • (S)-n,n-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl) propanamine-di-p-toluoyl-l-tartarate and methods of preparation thereof
    Publication number: 20060258871
    Abstract: The invention provides (S)-N,N-Dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine-Di-p-toluoyl-L-tartarate (DNT-L-pTTA), which can be used as an intermediate in the preparation of duloxetine hydrochloride, processes for the preparation of DNT-L-pTTA, a crystalline form of DNT-L-pTTA, and processes for the preparation of duloxetine hydrochloride form DNT-L-pTTA.
    Type: Application
    Filed: March 14, 2006
    Publication date: November 16, 2006
    Inventors: Santiago Ini, Tamas Koltai, Mili Abramov
  • Process for preparing pharmaceutically acceptable salts of duloxetine and intermediates thereof
    Publication number: 20060194869
    Abstract: Processes for preparing DNT-base, duloxetine alkyl carbamate, duloxetine-base and duloxetine hydrochloride, are provided. Also provided, are processes for converting DNT-base, duloxetine alkyl carbamate and duloxetine-base into pharmaceutically acceptable salts of duloxetine.
    Type: Application
    Filed: December 23, 2005
    Publication date: August 31, 2006
    Inventors: Santiago Ini, Anita Liberman
  • Purification of tegaserod maleate
    Publication number: 20060128788
    Abstract: Provided is a process for the purification of tegaserod maleate. Also provided is an isolated compound and the preparation thereof. This compound may be used as a reference marker and a reference standard, in the analysis of the purity of the tegaserod maleate.
    Type: Application
    Filed: October 19, 2005
    Publication date: June 15, 2006
    Inventors: Santiago Ini, Anita Liberman
  • Preparation of tegaserod and tegaserod maleate
    Publication number: 20060106086
    Abstract: Provided are processes for preparation of tegaserod and the maleate salt thereof.
    Type: Application
    Filed: April 26, 2005
    Publication date: May 18, 2006
    Inventors: Santiago Ini, Anita Liberman, Serguei Fine
  • Polymorphic forms of tegaserod base and salts thereof
    Publication number: 20050165085
    Abstract: Provided are polymorphic forms of tegaserod base and maleate, and processes for their preparation.
    Type: Application
    Filed: December 16, 2004
    Publication date: July 28, 2005
    Inventors: Marioara Mendelovici, Judith Aronhime, Santiago Ini, Greta Sterimbaum, Eran Luvchick