Abstract: Drug combinations of a heteroarotinoid (e.g., SHetA2, SHetA3, SHetA4, SHetC2, SHetD3, SHetD4, SHetD5, SHet50, SHet65, SHet100, OHet72, NHet17, NHet86, or NHet90), and an Azabicyclooctan-3-one derivative (e.g., PRIMA-1 or PRIMAMET) and/or a CDK4/6 inhibitor (e.g., Palbociclib, Abemaciclib, Ribociclib, Narazaciclib (ON123300), Dalpiciclib, Dinaciclib, Milciclib, Seliciclib), which are effective as anti-cancer treatments, and kits and methods of use of such drug combinations.

Abstract: A branch prediction system includes a neuron cache and logic coupled to the neuron cache. The neuron cache includes one or more weights of a neural network model trained for one or more selected code sections, and the logic is to be used with the neuron cache to predict a target address for a branch instruction of the one or more selected code sections.

Abstract: The present invention relates to a downhole inflow production restriction device for mounting in an opening in a well tubular metal structure arranged in a wellbore, the downhole inflow production restriction device comprising a device opening, and a brine dissolvable element configured to prevent flow from within the well tubular metal structure through the device opening to an outside of the well tubular metal structure before being at least partly dissolved in brine, wherein the brine dissolvable element is at least partly made of a magnesium alloy. The present invention also relates to a downhole completion system and to a completion method.

Abstract: Disclosed examples include flyback converters, control circuits and methods to facilitate secondary side regulation of the output voltage. A primary side control circuit operates a primary side switch to independently initiate power transfer cycles to deliver power to a transformer secondary winding in a first mode. A secondary side control circuit operates a synchronous rectifier or secondary side switch to generate a predetermined cycle start request signal via a transformer auxiliary winding to assume secondary side regulation and to cause the primary side controller to initiate new power transfer cycles.

Abstract: In some embodiments of the present disclosure, a modified compound is provided, which includes a polyether segment having an end including oxygen, sulfur or nitrogen; an amino acid moiety; and a group, which is an acryl group or an alkylacryl group, in which the amino acid moiety is bonded to the end of the polyether segment through a carbonyl group, and the amino acid moiety is bonded to the group through an amino group. In some embodiments of the present disclosure, a method for manufacturing the modified compound is also provided.

Abstract: An example assembly comprises: a main housing; an electric motor disposed in the main housing and comprising a stator fixedly positioned in the main housing, and a rotor positioned within the stator; a hydraulic pump positioned in the main housing and at least partially within the rotor, wherein the hydraulic pump is configured to receive fluid from an inlet port and provide fluid flow to an outlet port, wherein the hydraulic pump comprises a pump shaft rotatably coupled to the rotor of the electric motor; a controller housing coupled to the main housing; and a motor controller comprising one or more circuit boards disposed within the controller housing and configured to generate electric current to drive the electric motor.

Abstract: Aspects relate to a control message that includes at least one symbol mask to be applied to a set of symbols of a time slot. In some examples, the control message may also include at least one resource element mask to be applied to at least one resource element of the time slot. In some aspects, information may be communicated during the time slot according to the at least one symbol mask.

Abstract: Methods, systems, and computer readable media for limiting network function (NF) repository function (NRF) forwarding are disclosed. One example method for limiting NRF forwarding comprises: at a first NF comprising at least one processor: receiving a request message associated with a consumer NF; determining that the request message cannot be serviced by the first NF; inserting or modifying a forwarding limit value in the request message, wherein the forwarding limit value indicates a number of times that the request message can be forwarded; and forwarding the request message including the forwarding limit value toward a second NF.

Abstract: Systems and methods are provided for implementing a Siamese neural network using improved “sub” neural networks and loss function. For example, the system can detect a granular change in images using a Siamese Neural Network with Convolutional Autoencoders as the twin sub networks (e.g., Siamese AutoEncoder or “SAE”). In some examples, the loss function may be an adaptive loss function to the SAE network rather than a contrastive loss function, which can help enable smooth control of granularity of change detection across the images. In some examples, an image separation distance value may be calculated to determine the value of change between the image pairs. The image separation distance value may be determined using an Euclidean distance associated with a latent space of an encoder portion of the autoencoder of the neural networks.

Abstract: In some examples, a circuit includes a capacitor having a first terminal and a second terminal, the first terminal coupled to a voltage supply terminal of the circuit. The circuit also includes a transistor having a transistor gate, a transistor drain, and a transistor source, the transistor source coupled to ground and the transistor drain coupled to an input terminal of the circuit. The transistor is configured to conduct responsive to a gate signal received at the transistor gate, the gate signal based on a signal provided at the second terminal of the capacitor. The circuit also includes a Schmitt trigger having a Schmitt trigger input coupled to the transistor drain.

Abstract: In a method of making a carbon fiber, PAN (poly(acrylonitrile-co methacrylic acid)) is dissolved into a solvent to form a PAN solution. The PAN solution is extruded through a spinneret, thereby generating at least one precursor fiber. The precursor fiber is passed through a cold gelation medium, thereby causing the precursor fiber to gel. The precursor fiber is drawn to a predetermined draw ratio. The precursor fiber is continuously stabilized to form a stabilized fiber. The stabilized fiber is continuously carbonized thereby generating the carbon fiber. The carbon fiber is wound onto a spool. A carbon fiber has a fiber tensile strength in a range of 5.5 GPa to 5.83 GPa. The carbon fiber has a fiber tensile modulus in a range of 350 GPa to 375 GPa. The carbon fiber also has an effective diameter in a range of 5.1 ?m to 5.2 ?m.

Abstract: An authentication server can receive an electronic message transmitted by a sender. The electronic message can have an intended recipient and can include message data. A sender identification (“ID”) is embedded in the message data. The authentication server can generate a first message ID based on the message data that includes the sender ID. The first message ID can be determined to match a second message ID that is stored in a database. The sender ID can be determined to be different from an originator ID that is associated with the second message ID in the database. The authentication server can determine whether an originator associated with the originator ID has authorized the sender to transmit the message data and can determine whether to transmit the electronic message to the intended recipient based on whether the originator has authorized the sender to transmit the data.

Abstract: Various aspects of the present disclosure generally relate to wireless communication. In some aspects, a base station may extract information from a neighboring base station with cell coverage that overlaps cell coverage of the base station. The base station may determine, from the information, one or more locations of control resource sets (CORESETs) used by the neighboring base station. The base station may select resources that do not overlap with the CORESETs used by the neighboring base station. The base station may transmit a communication using the selected resources. Numerous other aspects are described.

Abstract: Crystalline forms of salts of Compound I are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed.

Abstract: The present disclosure provides compounds of Formula (I); or a pharmaceutically acceptable salt thereof, wherein each of Ring A, Ring B, Ra, Rb, L, R1, R2, m, and n is defined herein, pharmaceutical compositions thereof, methods of inhibiting ROCK1 and/or ROCK2, and methods of treating a ROCK1- and/or ROCK2-mediated disease or disorder.

Abstract: A zwitterionic compound has a structure of following formula (1), formula (2), formula (3), or formula (4): R1 is —O?, —(CH2)aSO3?, or —(CH2)bCO2?, a is 1 to 10, and b is 1 to 10. R2 and R3 are each independently an alkyl group or a phenyl group. x, z, and v are each independently 1 to 20. y and t are each independently 0 to 10.

Abstract: Methods, systems, and computer readable media for discovering network function (NF) service producers in a hierarchical network are disclosed. One method includes receiving, by a regional NF repository function (NRF) operating in a first region of a hierarchical network, a NF registration request message from a NF service producer operating in the first region and detecting, by the regional NRF, an absence of <NF-Type>Info and/or <NF-Type>InfoList attribute data in the received NF registration request message.

Abstract: Methods, systems, and devices for wireless communications are described. A first network entity may establish a sidelink connection with a first user equipment (UE). The first network entity may detect sidelink communications including sidelink data from the first UE, and may forward the detected sidelink data to a second network entity via a sidelink interface or a backhaul link. The second network entity may transmit the sidelink data to a second UE via a sidelink connection between the second network entity and the second UE.

Abstract: Systems and methods are provided for retraining machine learning (ML) models. Examples may automatically identify skewed, anomalous, and/or drift occurrence data in real-world input data. By automatically identifying such data, examples can reduce subjectivity in ML model retraining as well as reduce time spent determining a need to retrain a ML model. Accordingly, a determination can be made objectively by a computing system or device according to computer-implemented instructions. Additionally, examples may automatically isolate and transfer data relevant to the retraining of a ML model to a training environment for retraining the ML model using real-world input data. Examples also synthesize large samples of data for use in retraining a ML model. The synthesized data may be generated based on the isolated and transferred data and can be used in place of actual real-world input data to reduce a corresponding delay.

Abstract: Exhaust frequency mitigation apparatus, exhaust diffusers, and turbomachines are provided. An exhaust frequency mitigation apparatus includes a main body extending along an axial centerline from a base to a tip. the base defines a first diameter and the tip defining a second diameter. the main body converges from the first diameter to the second diameter with respect to the axial centerline. The base is configured to extend from an inner shell of a turbomachine exhaust diffuser. The exhaust frequency mitigation apparatus further includes at least one rib extending from a root coupled to the main body to a free end.