Abstract: Provided are a delivery system that is useful in delivering a double-stranded ribonucleic acid that functions in gene silencing in glomeruli, particularly in mesangial cells and the like, to the tissue or cells, and the like. A polyion complex in the form of a non-polymeric micelle consisting of a double-stranded ribonucleic acid and a block copolymer represented by the formula (I) or (II) below, which are electrostatically bound together, wherein the polyion complex has an average particle diameter of less than 100 nm as measured by a dynamic light scattering measuring method: wherein each symbol is as defined in the specification.

Abstract: An object of the present invention is to provide a guidewire having high safety and improved flexibility and rotation followability. This guidewire has an inner coil that surrounds a distal side portion of a core shaft, and an outer coil that surrounds the inner coil and the distal side portion of the core shaft. A front end of the outer coil and a front end of the inner coil are joined to a tip of the core shaft by a tip plug. Further, the guidewire has a coil joint that joins only the outer coil and the inner coil to each other. With this configuration, the flexibility of the inner coil is maintained. Moreover, rotation of a proximal side of the guidewire is transmitted to the inner coil not only from the core shaft but also from the outer coil. This leads to improvement in rotation followability.

Abstract: An object of the present invention is to provide a guidewire having high safety and improved flexibility and rotation followability, and capable of directing a catheter with ease. A guidewire of the present invention has an inner coil that surrounds a distal side portion of a core shaft, and an outer coil that surrounds the inner coil and the distal side portion of the core shaft. The core shaft has a second flat part in flattened shape in substantially contact with an inner peripheral surface of the inner coil. With this configuration, the distal side portion of the guidewire is protected by a double coil structure, while having high torsional stiffness. This leads to improvement in safety and rotation followability, while allowing a catheter to be directed with ease.

Abstract: Successfully produced are cruciferous plants resistant to clubroot by introducing the clubroot resistance gene (Crr1) isolated by map-based cloning into cruciferous plants and expressing the gene.

Abstract: A lens barrel assembly has a first groove formed in a stationary barrel. A second groove is formed in a rotatable barrel. A diaphragm control plate portion is disposed between an inner surface of the rotatable barrel and an iris diaphragm device in a rotatable manner in a circumferential direction, has an end portion connected to a driving ring. An engaging groove is formed in the diaphragm control plate portion to extend along the optical axis. An operable aperture ring is disposed outside the stationary barrel. A pin device has first and second end portions, the first end portion being secured fixedly to the aperture ring, the second end portion being inserted through the first and second grooves and the engaging groove, for operating upon rotation of the aperture ring to cause the engaging groove to rotate the diaphragm control plate portion to actuate the driving ring.

Abstract: According to an aspect of the invention, a sanitary washing apparatus, characterized by: a nozzle being configured to wash a body of a user by squirting water from a water discharge port; a flow channel configured to guide water supplied from a water supply source toward the water discharge port; an electrolytic cell provided at an intermediate portion of the flow channel, the electrolytic cell being capable of producing sterilizing water; and a nozzle wash unit configured to wash or sterilize the nozzle with the sterilizing water produced by the electrolytic cell, a contraction portion being formed downstream from the electrolytic cell, a flow channel cross-sectional area being smaller at the contraction portion than upstream from the electrolytic cell, a strainer being disposed in the flow channel further downstream from the contraction portion. Clogging of the flow channel due to scale can be suppressed.

Abstract: A display apparatus includes a display section which is attached to an electric vehicle EV operable upon supply of electric power thereto and displays information regarding the electric power supplied to the electric vehicle EV; a determination section which determines whether or not the electric power supplied to the electric vehicle EV contains green electric power; and a display control section. In the case where the determination section determines that the electric power supplied to the electric vehicle EV contains green electric power, the display control section controls the display section such that the display color becomes green. In the case where the determination section determines that the electric power supplied to the electric vehicle EV does not contain green electric power, the display control section controls the display section such that the display color becomes red.

Abstract: A guidewire includes a core shaft and a coil. The core shaft has a diameter that decreases from a proximal end portion toward a distal end portion, and the coil is wound around an outer periphery of the distal end portion. The distal end portion includes a most distal end portion that is positioned at a most distal end of the distal end portion, and an intermediate portion that is connected to the most distal end portion. The cross-sectional shape of the most distal end portion is a rectangular shape. The cross-sectional shape of the intermediate portion gradually changes from the rectangular shape to a circular shape in a direction from the most distal end portion toward the proximal end portion. The length of the most distal end portion is shorter than the length of the intermediate portion.

Abstract: According to one embodiment, a sanitary washing apparatus includes: a nozzle including a jetting port and configured to squirt water from the jetting port to wash a user's body; a flow channel configured to guide water supplied from a water supply source to the jetting port; an electrolytic cell provided midway along the flow channel and being operable to produce sterilizing water; a heating device provided on the flow channel on upstream side of the electrolytic cell; a nozzle cleaning device configured to clean or sterilize the nozzle with the water heated by the heating device or the sterilizing water produced by the electrolytic cell; and a controller configured to perform control for stopping energization of the heating device or reducing an amount of energization of the heating device when energizing the electrolytic cell.

Abstract: A time stamp is a device that prints time information on a time card inserted into a time card slot. The time card slot is formed to be inclined downwardly in the depthwise direction of the time stamp at an angle of 8 to 10 degrees or so with the mount surface of the time stamp being a reference. The time stamp has a mount portion to be attached to a wall surface. The time card slot extends in a direction orthogonal to the rear surface of the time stamp.

Abstract: A first operation portion and a second operation portion are depressed in a direction orthogonal to a surface of an electronic circuit board, at least the first operation portion is shifted relative to the center of a first switch, and travel distances or depression forces of a depression operation necessary for respective first and second protrusions to reach respective first and second depression faces are equal to each other.

Abstract: Disclosed is a siRNA-encapsulating polymeric micelle complex (a polyion complex) having high monodispersibility and structural stability and excellent in the ability of transporting siRNA into a cell. Further disclosed are a nucleic acid delivery device, a nucleic acid delivery kit, a pharmaceutical composition, and a gene therapy agent, each of which uses the complex. The polyion complex is characterized by comprising: a block copolymer composed of a polyethylene glycol moiety and a polycation moiety having a thiol group as a side chain at the terminus; and siRNA.

Abstract: Provided are a delivery system that is useful in delivering a double-stranded ribonucleic acid that functions in gene silencing in glomeruli, particularly in mesangial cells and the like, to the tissue or cells, and the like. A polyion complex in the form of a non-polymeric micelle consisting of a double-stranded ribonucleic acid and a block copolymer represented by the formula (I) or (II) below, which are electrostatically bound together, wherein the polyion complex has an average particle diameter of less than 100 nm as measured by a dynamic light scattering measuring method: wherein each symbol is as defined in the specification.

Abstract: Provided is a sound recording/playback device (1) that records onto a recording medium (5) sound data captured by a microphone (6), pulls the sound data from the recording medium (5), and plays said sound data. The sound recording/playback device is provided with a discrimination means (21, 22, 23, 24) which discriminates between human sound and non-sound audio. Upon recording, the device records the start position and end position of human sound, as determined by the discrimination means (21, 22, 23, 24), and upon playback, the data between the afore-mentioned start position and the subsequent end position is extracted and outputted.

Abstract: The power source apparatus is provided with batteries 1 that supply power to a load; a current regulating circuit 2 that controls battery 1 current; a fuse 6 connected in series with the batteries 1; a first computation circuit 3 that computes a first allowable current that can flow through the batteries 1 based on at least one parameter including battery 1 specified current, temperature, voltage, and remaining capacity; and a second computation circuit 4 that computes a second allowable current that can flow through the fuse 6 without blowing the fuse 6 based on the time integral of current flow through the fuse 6. The current regulating circuit 2 controls the battery 1 current to a value lower than the first allowable current computed by the first computation circuit 3 and the second allowable current computed by the second computation circuit 4.

Abstract: A washing machine and a control method thereof in which a tub washing course is safely performed using a sensor to measure vibration of a tub. Since whether or not laundry is present in s drum is sensed while performing the tub washing course, consumption of separate time, water, and energy to sense whether or not laundry is present is not required, and operation of the washing machine is controlled by diagnosing malfunction of the sensor. If plural sensors are installed, a micro-computer is connected to the plural sensors in common through a Serial Peripheral Interface (SPI) communication method or an Inter Integrated circuit (I2C) communication method, thereby reducing costs and volume of wire-harness.

Abstract: Provided is a music track extraction device, including: an audio power calculation section which calculates an audio power from an audio signal; and a judgment section which performs a judgment between a music track portion and a non-music track portion based on a state of the audio power.

Abstract: A lens barrel assembly has a first groove formed in a stationary barrel. A second groove is formed in a rotatable barrel. A diaphragm control plate portion is disposed between an inner surface of the rotatable barrel and an iris diaphragm device in a rotatable manner in a circumferential direction, has an end portion connected to a driving ring. An engaging groove is formed in the diaphragm control plate portion to extend along the optical axis. An operable aperture ring is disposed outside the stationary barrel. A pin device has first and second end portions, the first end portion being secured fixedly to the aperture ring, the second end portion being inserted through the first and second grooves and the engaging groove, for operating upon rotation of the aperture ring to cause the engaging groove to rotate the diaphragm control plate portion to actuate the driving ring.

Abstract: An aspect of the invention provides a commercial detection apparatus for detecting commercials that includes a silent detector configured to detect a silent segment based on the strength of the audio signal output in content, and a determination unit configured to determine a sound segment as a commercial if three or more silent segments are detected essentially within a set time span, and if the sound segment is found between two of the three silent segments.

Abstract: Characteristic amounts are calculated from each of multiple musical piece contents, and then time points when the characteristic amounts exceed a threshold are detected as cut points. Information on the cut point concerning each of the multiple musical piece contents is stored. Based on the stored information on the cut point, a judgment is made as to whether the multiple musical piece contents match each other.