Abstract: A method for producing pressure-responsive particles includes: adding an aggregating agent and a dispersion containing silica particles to a dispersion containing composite resin particles containing a styrene-based resin including a styrene compound and a vinyl monomer other than the styrene compound as polymer components and a (meth)acrylic acid ester-based resin including a (meth)acrylic acid ester compound as a polymer component to cause aggregation so as to form aggregated particles; and heating and fusing the aggregated particles to form pressure-responsive particles. The amount of the silica particles added by the dispersion containing the silica particles is 0.5 mass % or more and 10 mass % or less relative to a total mass of the composite resin particles. The mass ratio of the styrene-based resin to the (meth)acrylic acid ester-based resin in the pressure-responsive particles is from 80:20 to 20:80.

Abstract: Disclosed herein are a reactive emulsifier-containing composition, including: a reactive emulsifier represented by the following general formula (1); and water, wherein a content of the reactive emulsifier represented by the general formula (1) in the reactive emulsifier-containing composition is from 60 mass % to 98 mass %, and a method of storing the reactive emulsifier: where R represents a hydrocarbon group having 8 to 20 carbon atoms, “n” represents a number from 5 to 50, and M represents a hydrogen atom, an alkali metal atom, or an ammonium group.

Abstract: When it is determined that there is no possibility of a driver performing a predetermined steering operation for moving a host vehicle in a lateral direction without involving a change in a final travel direction, a vehicle control device sets a steering reaction force to be greater than a standard reaction force. When it is determined that there is a possibility thereof, the vehicle control device sets the steering reaction force to be smaller than the standard reaction force, and sets an increase rate of the steering reaction force relative to an increase in the amount of steering operation from a predetermined point in time after it is determined that there is a possibility of the driver performing the predetermined steering operation and before the amount of steering operation in the predetermined steering operation becomes largest to be higher than an increase rate before the predetermined point in time.

Abstract: Provided is a lens unit capable of reducing a risk that desired optical performance cannot be obtained even when a temperature range of a use environment is wide. In a lens unit including a first lens and a second lens, a diameter D1 of an outer peripheral edge of a first lens first tapered portion is set larger than a diameter D2 of an outer peripheral edge of a second lens tapered portion, and the outer peripheral edge of the first lens tapered portion and the outer peripheral edge of the second lens tapered portion are spaced apart by a predetermined distance at a predetermined temperature. In an environment at a temperature higher or lower than the predetermined temperature, the distance between the outer peripheral edge of the first lens tapered portion and the outer peripheral edge of the second lens tapered portion is set smaller than the predetermined distance.

Abstract: Pressure-responsive particles include pressure-responsive base particles and first inorganic oxide particles, in which the pressure-responsive base particles contain a styrene-based resin which contains styrene and other vinyl monomers as polymerization components and a (meth)acrylic acid ester-based resin which contains at least two kinds of (meth)acrylic acid esters as polymerization components and in which a mass ratio of the (meth)acrylic acid esters to all polymerization components is 90% by mass or higher, Db/Da which is a ratio of a number average particle diameter Db of the first inorganic oxide particles to a number average particle diameter Da of the pressure-responsive base particles is 0.05 or higher and 0.25 or lower, the pressure-responsive particles have at least two glass transition temperatures, and a difference between a lowest glass transition temperature and a highest glass transition temperature is 30° C. or higher.

Abstract: In a vehicle steering assist device that includes an electric power steering device that generates a control torque that modifies a return torque for urging a steering wheel to a neutral position, a steering assist ECU that controls the control torque, and a surrounding information detecting device (camera sensor, radar sensor) that detects at least information in front of a vehicle, the control torque is controlled such that a ratio of a change amount of the modified return torque to a change amount of a steering operation amount at the start of avoidance steering decreases when an obstacle is detected in front of the vehicle by the surrounding information detecting device and the avoidance steering for the vehicle to avoid collision with the obstacle is determined to be required.

Abstract: A method for producing a composite resin particle dispersion includes: performing polymerization A by polymerizing a styrene compound and a vinyl monomer other than the styrene compound to form a styrene-based resin; performing polymerization B by polymerizing a (meth)acrylic acid ester compound in the presence of the styrene-based resin to form intermediate resin particles containing the styrene-based resin and a (meth)acrylic acid ester-based resin; and performing polymerization C by polymerizing a styrene compound and a vinyl monomer other than the styrene compound in the presence of the intermediate resin particles to form composite resin particles. The mass ratio of the styrene-based resin to the (meth)acrylic acid ester-based resin in the composite resin particles is from 80:20 to 20:80. A difference between the lowest glass transition temperature and the highest glass transition temperature in the composite resin particles is 30° C. or more.

Abstract: A method for producing pressure-responsive particles includes: adding an aggregating agent to a dispersion containing composite resin particles containing a styrene-based resin including a styrene compound and a vinyl monomer other than the styrene compound as polymer components and a (meth)acrylic acid ester-based resin including a (meth)acrylic acid ester compound as a polymer component to aggregate the composite resin particles so as to form aggregated particles A; forming a shell by adding an aggregating agent and styrene-based resin particles containing a styrene compound and a vinyl monomer other than the styrene compound as polymer components to a dispersion containing the aggregated particles A to aggregate the styrene-based resin particles so as to form aggregated particles B; and heating and fusing the aggregated particles B to form pressure-responsive particles.

Abstract: A control unit that controls a reaction force actuator that applies steering guide torque to a steering wheel: calculates, based on a curvature of a curve of a travel road in front of a vehicle detected by a camera sensor, a target steering angle for causing the vehicle to travel along the curve; calculates a target steering guide torque, based on a deviation between the target steering angle that was calculated a prediction time period earlier and an actual steering angle; adjusts a target steering guide torque such that the target steering guide torque becomes smaller as a probability that a driver performs steering operation to deviate from a lane becomes higher; and controls the reaction force actuator such that the steering guide torque becomes the target steering guide torque.

Abstract: The object of the present invention is to provide a method for treating or preventing diseases related to mitochondrial function by a substance related to the improvement or decrease of mitochondrial function. The above problem can be solved by the agent for promoting formation of mitochondrial respiratory chain supercomplex, comprising Syk inhibitor as an active ingredient. a composition for maintaining or enhancing muscle strength, comprising the agent for promoting formation of mitochondrial respiratory chain supercomplex, or the pharmaceutical composition for treating or preventing muscle hypofunction disease or mitochondrial hypofunction disease, comprising the agent for promoting formation of mitochondrial respiratory chain supercomplex, of the present invention.

Abstract: A control unit that controls a reaction force actuator that applies steering guide torque to a steering wheel: calculates, based on a curvature of a curve of a travel road in front of a vehicle detected by a camera sensor, a target steering angle for causing the vehicle to travel along the curve; calculates a target steering guide torque, based on a deviation between the target steering angle that was calculated a prediction time period earlier and an actual steering angle; adjusts a target steering guide torque such that the target steering guide torque becomes smaller as a probability that a driver performs steering operation to deviate from a lane becomes higher; and controls the reaction force actuator such that the steering guide torque becomes the target steering guide torque.

Abstract: A temperature control system includes a battery; a power electronics device that converts high-voltage electric power; an air passage; an inside-air intake passage and an outside-air intake passage that acquire inside air and outside air of a vehicle, and supply the airs to the air passage; an intake opening/closing member that opens and closes between the air passage and each of the intake passages; a passage switch that switches among a power-electronics prioritized state, a battery prioritized state, and a retention state; and a control device including a processor and a memory coupled to the processor. In a state in which a temperature of the outside air is lower than a battery lower limit temperature, the processor performs switching control of a power-electronics prioritized state, a battery prioritized state, and a retention state with the passage switches, based on an output value of the power electronics device.

Abstract: A vehicle steering assist device includes a steering assist ECU. The steering assist ECU calculates a target steering angle for driving the vehicle along the road, and a target steering guide torque that guides the driver's steering so that the actual steering angle becomes the target steering angle. The steering assist ECU controls the torque applying device so that the steering guide torque becomes the target steering guide torque. The steering assist ECU acquires at least one of information on the driving environment of the vehicle and information on the state of the driver, and calculates an index value indicating the necessity of the steering guide torque based on at least one of the pieces of information. The steering assist ECU corrects the target steering guide torque based on the index value so that the higher the need for the steering guide torque, the larger the target steering guide torque.

Abstract: A vehicle steering control device includes a control device. The control device is configured to control a steering reaction force to be applied to a steering operation performed by a driver of a driver's vehicle, acquire information on a curved road ahead of the driver's vehicle in a traveling direction, set a guide steering operation amount based on the information on the curved road, predict a time at which the driver starts an actual steering operation for driving the driver's vehicle along the curved road as a steering operation start time, and set, based on a difference between the guide steering operation amount and an actual amount of the steering operation, the steering reaction force at a time earlier by a predetermined period than the steering operation start time.

Abstract: Pressure-responsive particles include pressure-responsive base particles and fatty acid metal salt particles, in which the pressure-responsive base particles contain a styrene-based resin which contains styrene and other vinyl monomers as polymerization components and a (meth)acrylic acid ester-based resin which contains at least two kinds of (meth)acrylic acid esters as polymerization components and in which amass ratio of the (meth)acrylic acid esters to all polymerization components is 90% by mass or higher, the pressure-responsive particles have at least two glass transition temperatures, and a difference between the lowest glass transition temperature and the highest glass transition temperature is 30° C. or higher.

Abstract: An antibody-drug conjugate represented by formula (I): (where Ab is an antibody, X is a group represented by formula (X-1), formula (X-2) or formula (X-3): (where at the left represents the binding site with NH and at the right represents the binding side with D), D is a group represented by formula (D-1) or formula (D-2): (where represents the binding site with X), and n is in the range of about 1 to about 8).

Abstract: The present invention relates a combination drug for treating a renal cancer and a potentiator for therapeutic effects of a tyrosine kinase inhibitor. The combination drug includes a combination of a tyrosine kinase inhibitor, and a dipeptidyl peptidase-4 inhibitor. The potentiator includes a dipeptidyl peptidase-4 inhibitor. The potentiator enhances therapeutic effects of a tyrosine kinase inhibitor on a renal cancer.

Abstract: A shell and plate heat exchanger includes a shell and a plate pack. The shell defines a cavity configured to receive a first fluid and a second fluid. The plate pack is arranged inside the cavity. The plate pack has a plurality of heat exchanger plates. Each of the heat exchanger plates has two sides facing in opposite directions in a thickness direction of the heat exchanger plate. At least one of the sides of at least one of the heat exchanger plates has a surface roughness of between 5 ?m and 100 ?m.

Abstract: Pressure-responsive particles include pressure-responsive base particles and fatty acid metal salt particles, in which the pressure-responsive base particles contain a styrene-based resin which contains styrene and other vinyl monomers as polymerization components and a (meth)acrylic acid ester-based resin which contains at least two kinds of (meth)acrylic acid esters as polymerization components and in which amass ratio of the (meth)acrylic acid esters to all polymerization components is 90% by mass or higher, the pressure-responsive particles have at least two glass transition temperatures, and a difference between the lowest glass transition temperature and the highest glass transition temperature is 30° C. or higher.

Abstract: A charging prediction system includes vehicles, a charging station, and a control device including one or more processors and one or more memories. The one or more processors are configured to execute a process. The process includes accumulating, in a storage device, record data that is actual data on a charged vehicle ratio for a first remaining traveling distance of each of the vehicles traveling along a specific traveling road. The process includes deriving, based on the record data, a predicted value of the charged vehicle ratio for each vehicle in a predetermined group including ones of the vehicles currently traveling along the specific traveling road. The process includes deriving a predicted waiting period that is a predicted value of a waiting period to a start of charging at the charging station based on the predicted values of the charged vehicle ratios.