Abstract: The present invention provides a composition that controls pharmacokinetics. Specifically, the present invention provides: a composition for controlling pharmacokinetics, the composition containing a polyvalent cation as an active ingredient; and a method for controlling pharmacokinetics using the polyvalent cation.

Abstract: Provided are a hot dip galvanized steel sheet comprising a base steel sheet wherein the base steel sheet has a predetermined composition and contains ferrite: 0% to 50%, retained austenite: 0% to 30%, tempered martensite: 5% or more, fresh martensite: 0% to 10%, and pearlite and cementite in total: 0% to 5%, remaining structures consist of bainite, when defining a region having a hardness of 90% or less of the hardness at a position of ¼ thickness to the base steel sheet side from an interface of the base steel sheet and a hot dip galvanized layer as a “soft layer”, there is a soft layer having a thickness of 10 ?m or more at the base steel sheet side from the interface, the soft layer contains tempered martensite, and an increase rate in a thickness direction of an area % of tempered martensite from the interface to the inside of the base steel sheet inside the soft layer is 5.0%/?m or less, and a method for producing the same.

Abstract: A hot dip galvanized steel sheet includes a base steel sheet and a hot dip galvanized layer on at least one surface of the base metal steel sheet, wherein the base steel sheet has a predetermined chemical composition, and contains, by volume fraction, ferrite: 0% to 50%, retained austenite: 0% to 30%, tempered martensite: 5% or more, fresh martensite: 0% to 10%, and pearlite and cementite in total: 0% to 5%, when there are remaining structures, the remaining structures consist of bainite, a concentration of B atoms at prior austenite grain boundaries is 2.0 atm % or more, and an average effective crystal grain size is 7.0 ?m or less, and a method for producing the same.

Abstract: The present invention provides a composition that controls pharmacokinetics. Specifically, the present invention provides: a composition for controlling pharmacokinetics, the composition containing a polyvalent cation as an active ingredient; and a method for controlling pharmacokinetics using the polyvalent cation.

Abstract: A hot dip galvanized steel sheet includes a base steel sheet and a hot dip galvanized layer on at least one surface of the base metal steel sheet, wherein the base steel sheet has a predetermined chemical composition, and contains, by volume fraction, ferrite: 0% to 50%, retained austenite: 0% to 30%, tempered martensite: 5% or more, fresh martensite: 0% to 10%, and pearlite and cementite in total: 0% to 5%, when there are remaining structures, the remaining structures consist of bainite, a concentration of B atoms at prior austenite grain boundaries is 2.0 atm % or more, and an average effective crystal grain size is 7.0 ?m or less, and a method for producing the same.

Abstract: A simulation apparatus includes a machine learning device for learning a change in a machining route in machining of a workpiece. The machine learning device observes data indicating the changed machining route and data indicating a machining condition of the workpiece as a state variable, and also acquires determination data for determining whether or not a cycle time obtained by simulation using the changed machining route is appropriate, and learns by associating the machining condition of the workpiece with the change in the machining route, using the state variable and the determination data.

Abstract: An electrolyte solution for an alkali metal-sulfur-based secondary battery, an alkali metal-sulfur-based secondary battery, and a module containing the alkali metal-sulfur-based secondary battery. The electrolyte solution includes a positive electrode containing a carbon composite material that contains a carbon material and a sulfur-containing positive electrode active material. The carbon material has a pore volume ratio (micropores/mesopores) of 1.5 or higher. The electrolyte solution contains a fluorinated ether represented by the following formula (1): R11—(OR12)n11—O—R13. In the formula, R11 and R13 are the same as or different from each other, and are each an alkyl group optionally containing a fluorine atom, with at least one of R11 or R13 containing a fluorine atom; R12 is an alkylene group optionally containing a fluorine atom; and n11 is 0, 1, or 2.

Abstract: A zinc-plated steel sheet includes a steel sheet having a predetermined chemical composition and a zinc-plated layer. In the steel sheet, steel microstructures in a range of ? thickness to ? thickness, having the center at ¼ thickness from a steel sheet surface, include, by vol %, ferrite: 0% to 10%, bainite: 0% to 30%, tempered martensite: 50% or more, fresh martensite: 0% to 10%, retained austenite: more than 10% and 30% or less, and pearlite: 0% to 5%. In the zinc-plated steel sheet, the amount of hydrogen emitted when the steel sheet is heated to 200° C. from room temperature after removal of the zinc-plated layer is 0.40 ppm or less per mass of the steel sheet, the tensile strength is 1470 MPa or more, and no cracking occurs in a U-shape bending test where a stress equivalent to 1000 MPa is applied for 24 hours.

Abstract: Provided are a hot dip galvanized steel sheet comprising a base steel sheet and a hot dip galvanized layer on at least one surface of the base metal steel sheet, wherein the base steel sheet has a predetermined chemical composition and contains, by volume fraction, ferrite: 0% to 50%, retained austenite: 6% to 30%, bainite: 5% or more, tempered martensite: 5% or more, fresh martensite: 0% to 10%, and pearlite and cementite in total: 0% to 5%, a number density of tempered martensite with a circle equivalent diameter of 5.0 ?m or more is 20/1000 ?m2 or less, and an area ratio of fresh martensite with a circle equivalent diameter of 2.0 ?m or more after imparting 5% plastic strain is 10% or less, and a method for producing the same.

Abstract: An optical assembly includes a spacer layer which is translucent or transparent; an image forming reflector which has a reflective layer being formed at least in a first region of the spacer layer; and a protective layer which is laminated over the spacer layer and the image forming reflector and the protective layer being translucent or transparent. The spacer layer is made of a polyolefin or/and a polymer containing an aryl group. The image forming reflector includes a visible image which is authenticatable. The image forming reflector has an individual information record in which a code is stored in the form of a plurality of removed linear segments. The image forming reflector has white level regions and a black level region in planar view. Each of the white level regions has the removed linear segments formed therein. The black level region is interposed between the white level regions.

Abstract: A zinc-plated steel sheet of an aspect of the present invention includes a steel sheet having a predetermined chemical composition and a zinc-plated layer. In the steel sheet, steel microstructures in a range of ? thickness to ? thickness, having the center at ¼ thickness from a steel sheet surface, include, by vol %, ferrite: 0% to 10%, bainite: 0% to 20%, tempered martensite: 70% or more, fresh martensite: 0% to 10%, retained austenite: 0% to 10%, and pearlite: 0% to 5%. In the zinc-plated steel sheet, the amount of hydrogen emitted when the steel sheet is heated to 200° C. from a room temperature after removal of the zinc-plated layer is 0.40 ppm or less per mass of the steel sheet, the tensile strength is 1470 MPa or more, and no cracking occurs in a U-shape bending test where a stress equivalent to 1000 MPa is applied for 24 hours.

Abstract: An optical identifier including a recording surface, a plurality of deflection cells each of which has recorded thereon a range in which light to be diffracted is deflected, at least one spatial phase modulator which fills a space between the deflection cells on the recording surface, and a deposition layer which covers part or all of the recording surface. The deflection cells has a spatial frequency expressed in a form of a relief structure and are discretely formed on the recording surface at regular intervals away from each other. A variable color image is recorded by pixels defined by the deflection cells. The spatial phase modulator has thereon a distribution of phase differences recorded in a form of heights of the relief structure. The spatial phase modulator modulates a phase of light outputted from a point light source and displays a reproduced image.

Abstract: A caulking pin (15) is inserted into a mounting hole (21) provided in a metal case body (3), and the end portion of the caulking pin (15) is thermally caulked with a welding tip (24) to form a mold forming portion (17). A surplus absorption recess (31) is formed by enlarging the opening end of the mounting hole (21), and surplus resin is absorbed. The surplus absorption recess (31) is positioned inside a region of the mold forming portion (17). Therefore, the amount of molten surplus resin that protrudes outward from the welding tip (24) in the thermal caulking process is reduced.

Abstract: The present invention provides a functionalized mRNA including mRNA and double-stranded RNA including at least one RNA oligomer hybridized with mRNA. Functionalized mRNA is provided according to this configuration.

Abstract: A steel sheet wherein a steel structure of an inside of the steel sheet contains, by volume fraction, soft ferrite: 0% to 30%, retained austenite: 3% to 40%, fresh martensite: 0% to 30%, a sum of pearlite and cementite: 0% to 10%, and a remainder including hard ferrite. In the steel sheet, in a ? to ? thickness range, a proportion of retained austenite having an aspect ratio of 2.0 or more is 50% or more, and a soft layer having a thickness of 1 to 100 ?m from a surface in a sheet thickness direction is present. When an emission intensity at a wavelength indicating Si is analyzed in the sheet thickness direction from the surface by a radio-frequency glow discharge analysis method, a peak of the emission intensity appears in a range of more than 0.2 ?m and 5.0 ?m or less from the surface.

Abstract: In a thickness range of which center is a ¼ thickness from the surface of a base steel sheet, a volume fraction of a ferrite phase is 0% to less than 50%, a volume fraction of the total of a hard structure composed of one or more of a bainite structure, a bainitic ferrite phase, a fresh martensite phase, and a tempered martensite phase is 50% or more, a volume fraction of a retained austenite phase is 0-8%, and a volume fraction of the total of a pearlite phase and a coarse cementite phase is 0-8%, at an interface between a plating layer and the base steel sheet, a Fe—Al alloy layer is provided, the Fe—Al alloy layer having an average thickness of 0.1-2.0 ?m and a difference between a maximum thickness and a minimum thickness in the width direction of the steel sheet being within 0.5 ?m.

Abstract: A numerical controller according to the present invention stores comparative relationship between parameters related to setting of the numerical controller, extracts data having comparative relationship among parameters related to the setting of the numerical controller based on the stored comparative relationship, and causes a display to display the data having the comparative relationship in association with each other.

Abstract: A steel sheet has a chemical composition with a steel structure containing, by volume fraction, soft ferrite: 0-30%, retained austenite: 3-40%, fresh martensite: 0-30%, pearlite and cementite: 0-10%, and a remainder including hard ferrite. In the steel sheet, a number proportion of retained austenite having an aspect ratio of 2.0 or more in the total retained austenite is 50% or more, and a soft layer having a thickness of 1-100 ?m is present. In the soft layer, a volume fraction of ferrite grains having an aspect ratio of less than 3.0 is 50% or more, and a volume fraction of retained austenite is 50% or more of the volume fraction of the retained austenite of the inside of the steel sheet. A peak of an emission intensity at a wavelength indicating Si appears in a range of more than 0.2 ?m to 5 ?m or less from the surface.

Abstract: The present invention provides a functionalized mRNA including mRNA and double-stranded RNA including at least one RNA oligomer hybridized with mRNA. Functionalized mRNA is provided according to this configuration.

Abstract: A control device controls display of a display device for displaying a display screen for setting operations of the control device that controls an industrial machine and soft keys for operating the display screen. The control device includes: a key input processing unit that receives input from an input device; an input content determining unit that determines a content of the input received by the key input processing unit; a storage unit that stores a soft key definition information table in which operation contents on the display screen to be allocated to the soft keys are defined in advance; a soft key allocation selecting unit that selects the operation contents to be allocated to the soft keys; and a soft key display processing unit that displays the soft keys allocated with the operation contents selected by the soft key allocation selecting unit on the display device.