Abstract: The present invention provides a composition for transdermal administration comprising a nucleic acid. Specifically, the present invention provides a composition for transdermal administration comprising a nucleic acid, the nucleic acid comprising RNA, wherein the composition is administered by an administration method comprising spraying the composition to the surface of a target tissue, and the spraying of the composition is performed by pressurization of the composition, whereby the composition is sprayed toward the target tissue and penetrates the surface of the target tissue.

Abstract: A communication method, which is executed by a communication apparatus among a plurality of communication apparatuses connected in multiple stages includes steps of acquiring downlink optical signals having one or more wavelengths including a predetermined reception wavelength from a previous stage and transmitting a communication situation signal or an allocation request signal of the communication apparatus to the previous stage using uplink optical signals having one or more wavelengths including a predetermined transmission wavelength, selecting a downlink optical signal having the reception wavelength, acquiring an allocation control signal indicating allocation of the reception wavelength and the transmission wavelength from the selected downlink optical signal having the reception wavelength, updating the reception wavelength and the transmission wavelength in accordance with the acquired allocation control signal, and transmitting an uplink optical signal having the updated transmission wavelength to

Abstract: A power storage device includes a case lid with a terminal inserting hole, a current collecting terminal having a hole insertion portion inserted in the terminal inserting hole in a case front-back direction and an external connection portion continuous with the hole insertion portion and placed in parallel to the case lid on the case front-surface side, and an insulating resin member integrally molded with the current collecting terminal and the case lid to connect the hole insertion portion and the external connection portion to a hole outer edge portion and a hole surrounding portion. The insulating resin member includes a back-surface side insulating resin portion connecting a back surface of the external connection portion and the hole insertion portion to the hole outer edge portion and the hole surrounding portion. The back-surface side insulating resin portion is formed with a recessed portion opening on a case back-surface side.

Abstract: A power storage device includes a case lid member, a terminal member, and a resin member. The resin member includes a resin outer portion, a resin inner portion, and a resin inside-hole portion. The case lid member and the resin member are configured that, when the power storage device is placed under a temperature environment of ?40° C., the resin member forms an outward convex warp in a lid thickness direction with respect to a lid longitudinal direction so that a pair of longitudinal joint faces of the resin inner portion press the terminal member in the lid longitudinal direction.

Abstract: A power storage device includes a case lid with a terminal inserting hole, a current collecting terminal having a hole insertion portion inserted in the terminal inserting hole and an external connection portion placed on a front surface side of the case lid, and an insulating resin member integrally molded with the current collecting terminal and the case lid. The insulating resin member includes an outer-periphery-side insulating resin portion and a back-surface side insulating resin portion connecting the current collecting terminal and the case lid. The back-surface side insulating resin portion is formed with a hollow portion penetrating through a back surface of the back-surface side insulating resin portion to a back surface of the outer connecting portion. The back surface of the outer connecting portion is formed with an annular band-shaped sealing portion along the outer edge portion of the hollow portion.

Abstract: In a battery, a lid member of a battery case is provided with a terminal part and a resin member. The terminal part has a terminal plate-shaped portion located inside the battery case, which extends wider than a through hole along an inner surface of the lid member. The resin member has an inner resin plate-shaped portion located between the inner surface of the lid member and the terminal plate-shaped portion. The lid member, on the inner surface side around the through hole, includes a protruding portion defined by a protruding inner surface joined to the inner resin plate-shaped portion and protruding toward the inside of the battery case relative to a non-protruding inner surface farther from the through hole than the protruding inner surface. Side surfaces of the protruding portion and the terminal plate-shaped portion do not project outward beyond a side surface of the inner resin plate-shaped portion.

Abstract: A method of manufacturing a power storage device includes a laser welding step in which a laser beam is irradiated to an opening portion of a case body and a peripheral portion of a case lid member of a lid assembly over the entire circumference to laser weld them while the opening portion of the case body is closed by the case lid member, a shielding step, prior to the laser welding step, in which a shield member is placed in position on the lid assembly to prevent scattered light of the laser beam from reaching a resin member, and a removing step, after the laser welding step, in which the shield member is removed.

Abstract: A power storage device has a case member, a terminal member, and a resin member subjected to insert molding to fix the terminal member to the case member. The resin member is made of a resin material including a thermoplastic main resin having a first glass transition temperature equal to or higher than 70° C., a thermoplastic elastomer, and a filler. The elastomer has a second glass transition temperature that is equal to or higher than ?10° C. and equal to or lower than 20° C. and a third glass transition temperature equal to or lower than ?40° C.

Abstract: A power storage device includes a current collecting terminal, a case member having a terminal insertion hole, and an insulating resin member connecting the current collecting terminal with a hole periphery and a hole surrounding portion of the terminal insertion hole. The current collecting terminal and the case member have seal portions that ensure airtightness in a case, at connecting portions connecting with the insulating resin member, and each of the seal portions is a roughened surface. The insulating resin member has a thermoplastic resin material including high molecular weight particles with a molecular weight of 10,000 or more and low molecular weight particles with a molecular weight of 500 to 5,000, and the low molecular weight particles are included 5 to 15% by weight in the thermoplastic resin material and are unevenly distributed closer to the roughened surface.

Abstract: A power storage device has a case member, a first terminal member, a second terminal member, a first resin member hermetically joined to the case member and the first terminal member, and a second resin member hermetically joined to the case member and the second terminal member. The first resin member is made of a first resin material having a resin material linear expansion coefficient ? within the range of 1.6×10?5 to 2.7×10?5 (1/K), and the second resin member is made of a second resin material that is different from the first resin material and has a resin material flexural modulus E of 17 GPa or less.

Abstract: The present disclosure provides an outer net blade member capable of forming an outer net blade capable of shaving hair more efficiently, the outer net blade formed using the outer net blade member, and an electric razor including the outer net blade. The outer net blade member according to the present disclosure is capable of forming the outer net blade provided on the electric razor. The outer net blade member includes a cuttable region in which multiple blade holes each in a substantially hexagonal shape are formed in rows in a first direction and a second direction orthogonal to the first direction. The blade holes are formed in a state of forming a row in the second direction in which the blade holes adjacent to each other in the second direction are shifted from each other in position in the first direction.

Abstract: The present invention provides a composition that controls pharmacokinetics. Specifically, the present invention provides: a composition for controlling pharmacokinetics, the composition containing a polyvalent cation as an active ingredient; and a method for controlling pharmacokinetics using the polyvalent cation.

Abstract: Provided are a hot dip galvanized steel sheet comprising a base steel sheet wherein the base steel sheet has a predetermined composition and contains ferrite: 0% to 50%, retained austenite: 0% to 30%, tempered martensite: 5% or more, fresh martensite: 0% to 10%, and pearlite and cementite in total: 0% to 5%, remaining structures consist of bainite, when defining a region having a hardness of 90% or less of the hardness at a position of ¼ thickness to the base steel sheet side from an interface of the base steel sheet and a hot dip galvanized layer as a “soft layer”, there is a soft layer having a thickness of 10 ?m or more at the base steel sheet side from the interface, the soft layer contains tempered martensite, and an increase rate in a thickness direction of an area % of tempered martensite from the interface to the inside of the base steel sheet inside the soft layer is 5.0%/?m or less, and a method for producing the same.

Abstract: A hot dip galvanized steel sheet includes a base steel sheet and a hot dip galvanized layer on at least one surface of the base metal steel sheet, wherein the base steel sheet has a predetermined chemical composition, and contains, by volume fraction, ferrite: 0% to 50%, retained austenite: 0% to 30%, tempered martensite: 5% or more, fresh martensite: 0% to 10%, and pearlite and cementite in total: 0% to 5%, when there are remaining structures, the remaining structures consist of bainite, a concentration of B atoms at prior austenite grain boundaries is 2.0 atm % or more, and an average effective crystal grain size is 7.0 ?m or less, and a method for producing the same.

Abstract: The present invention provides a composition that controls pharmacokinetics. Specifically, the present invention provides: a composition for controlling pharmacokinetics, the composition containing a polyvalent cation as an active ingredient; and a method for controlling pharmacokinetics using the polyvalent cation.

Abstract: A hot dip galvanized steel sheet includes a base steel sheet and a hot dip galvanized layer on at least one surface of the base metal steel sheet, wherein the base steel sheet has a predetermined chemical composition, and contains, by volume fraction, ferrite: 0% to 50%, retained austenite: 0% to 30%, tempered martensite: 5% or more, fresh martensite: 0% to 10%, and pearlite and cementite in total: 0% to 5%, when there are remaining structures, the remaining structures consist of bainite, a concentration of B atoms at prior austenite grain boundaries is 2.0 atm % or more, and an average effective crystal grain size is 7.0 ?m or less, and a method for producing the same.

Abstract: A simulation apparatus includes a machine learning device for learning a change in a machining route in machining of a workpiece. The machine learning device observes data indicating the changed machining route and data indicating a machining condition of the workpiece as a state variable, and also acquires determination data for determining whether or not a cycle time obtained by simulation using the changed machining route is appropriate, and learns by associating the machining condition of the workpiece with the change in the machining route, using the state variable and the determination data.

Abstract: An electrolyte solution for an alkali metal-sulfur-based secondary battery, an alkali metal-sulfur-based secondary battery, and a module containing the alkali metal-sulfur-based secondary battery. The electrolyte solution includes a positive electrode containing a carbon composite material that contains a carbon material and a sulfur-containing positive electrode active material. The carbon material has a pore volume ratio (micropores/mesopores) of 1.5 or higher. The electrolyte solution contains a fluorinated ether represented by the following formula (1): R11—(OR12)n11—O—R13. In the formula, R11 and R13 are the same as or different from each other, and are each an alkyl group optionally containing a fluorine atom, with at least one of R11 or R13 containing a fluorine atom; R12 is an alkylene group optionally containing a fluorine atom; and n11 is 0, 1, or 2.

Abstract: A zinc-plated steel sheet includes a steel sheet having a predetermined chemical composition and a zinc-plated layer. In the steel sheet, steel microstructures in a range of ? thickness to ? thickness, having the center at ¼ thickness from a steel sheet surface, include, by vol %, ferrite: 0% to 10%, bainite: 0% to 30%, tempered martensite: 50% or more, fresh martensite: 0% to 10%, retained austenite: more than 10% and 30% or less, and pearlite: 0% to 5%. In the zinc-plated steel sheet, the amount of hydrogen emitted when the steel sheet is heated to 200° C. from room temperature after removal of the zinc-plated layer is 0.40 ppm or less per mass of the steel sheet, the tensile strength is 1470 MPa or more, and no cracking occurs in a U-shape bending test where a stress equivalent to 1000 MPa is applied for 24 hours.

Abstract: Provided are a hot dip galvanized steel sheet comprising a base steel sheet and a hot dip galvanized layer on at least one surface of the base metal steel sheet, wherein the base steel sheet has a predetermined chemical composition and contains, by volume fraction, ferrite: 0% to 50%, retained austenite: 6% to 30%, bainite: 5% or more, tempered martensite: 5% or more, fresh martensite: 0% to 10%, and pearlite and cementite in total: 0% to 5%, a number density of tempered martensite with a circle equivalent diameter of 5.0 ?m or more is 20/1000 ?m2 or less, and an area ratio of fresh martensite with a circle equivalent diameter of 2.0 ?m or more after imparting 5% plastic strain is 10% or less, and a method for producing the same.