Abstract: There is provided an airbag device with a reduced risk of injury to an occupant in the initial inflation and deployment of an airbag. The airbag has a roll folded portion in the rear side of a vehicle thereof, and a flip folded portion in the front side of the vehicle thereof, and is surrounded by a holding member. The holding member permits inflation and deployment of the airbag only from an opening. The flap has a first restricting portion, a second restricting portion and a third restricting portion joined together in a Y shape, and restricts the inflation and deployment of the airbag. The first restricting portion covers a portion of the roll folded portion of the opening side, and is disposed between the roll folded portion and the holding member. A tip of the second restricting portion is secured to the flip folded portion. The third restricting portion is folded into the flip folded portion.

Abstract: According to one embodiment, an X-ray diagnostic apparatus includes a first arm, a second arm, an imaging system and a slide mechanism. The first arm rotates by a first rotating shaft and slides along with a first arc-like slide axis relatively to the first rotating shaft. The second arm rotates by a second rotating shaft fixed to the first arm and slides along with a second arc-like slide axis relatively to the second rotating shaft. The imaging system includes an X-ray generating part and an X-ray detector. The X-ray generating part and the X-ray detector are attached to the second arm. The slide mechanism slides the first arm along with the first slide axis. The slide mechanism is arranged at a position having an offset from the first rotating shaft.

Abstract: A shift control apparatus of an automatic transmission includes: an input detecting unit configured to detect a real rotational speed of the input shaft; an output detecting unit configured to detect a real rotational speed of the output shaft; an estimating unit configured to estimate an estimated rotational speed of the input shaft, which corresponds to a shift request, by multiplying the real rotational speed of the output shaft by a target gear ratio; and a control unit configured to control the rotation of the input shaft based on a detection result from the input detecting unit. The control unit controls the rotation of the input shaft such that an upper-limiting rotational speed of a variation in real rotational speed of the input shaft is lower than the estimated rotational speed.

Abstract: The present invention provides an effective method for fractionating rubber particles in natural rubber latex by particle size, and effective methods for transporting or preserving rubber particles. The present invention relates to a method for fractionating rubber particles in natural rubber latex by particle size, the method including centrifuging natural rubber latex in at least four stages at forces of 800 to 3,000×g, 6,500 to 10,000×g, 17,000 to 22,000×g, and 40,000 to 60,000×g to fractionate rubber particles. The present invention also relates to methods for transporting or preserving rubber particles, the methods including the steps of adding a buffer solution and an antioxidant to natural rubber latex or rubber particles fractionated from natural rubber latex; and freezing a mixture prepared in the above step.

Abstract: An X-ray image generating unit alternately generates X-ray images each obtained by radiating X-rays having a higher level of energy and X-ray images each obtained by radiating X-rays having a lower level of energy. Further, every time an X-ray image has been generated by the X-ray image generating unit, a dual energy subtraction image generating unit generates a dual energy subtraction image by using the X-ray image that has just been generated and the X-ray image generated immediately preceding the X-ray image.

Abstract: Disclosed is a method for detecting a rare mutation. The method comprises: preparing a sample comprising not more than 1,000 copies of template DNA; amplifying the template DNA to prepare a library, and analyzing a nucleotide sequence of the library; calculating a ratio of variants in a base at a predetermined position, from the analysis result; comparing the calculated ratio of variants with a predetermined cut-off value; and determining that the sample has a rare mutation in the base at the predetermined position when the calculated ratio of variants is not less than the predetermined cut-off value.

Abstract: There is provided an airbag device with a reduced risk of injury to an occupant in the initial inflation and deployment of an airbag. The airbag has a roll folded portion in the rear side of a vehicle thereof, and a flip folded portion in the front side of the vehicle thereof, and is surrounded by a holding member. The holding member permits inflation and deployment of the airbag only from an opening. The flap has a first restricting portion, a second restricting portion and a third restricting portion joined together in a Y shape, and restricts the inflation and deployment of the airbag. The first restricting portion covers a portion of the roll folded portion of the opening side, and is disposed between the roll folded portion and the holding member. A tip of the second restricting portion is secured to the flip folded portion. The third restricting portion is folded into the flip folded portion.

Abstract: A single different-thickness plate (18) is formed by performing double-side welding from both sides in a plate thickness direction of a first front lower plate (17A) having a plate thickness equal to a plate thickness of a lower joining plate (33F) of an arm-side mounting member (33) and a second front lower plate (17B) having a plate thickness equal to a plate thickness of a third front lower plate (17C). As a result, one-side welding can be performed by using a backing material (23) from an outer side of a box-shaped structural body (12) to the lower joining plate (33F) of the arm-side mounting member (33) and to the first front lower plate (17A) constituting the different-thickness plate (18).

Abstract: Provided is a method for producing a polyisoprenoid, which can increase natural rubber production by enhancing the rubber synthesis activity of rubber particles. The present invention provides methods for producing a polyisoprenoid using a gene coding for a cis-prenyltransferase (CPT) family protein, a gene coding for a Nogo-B receptor (NgBR) family protein and a gene coding for a rubber elongation factor (REF) family protein, specifically a method for producing a polyisoprenoid in vitro using rubber particles bound to proteins coded for by these genes, and a method for producing a polyisoprenoid in vivo using a recombinant organism (plant) having these genes introduced therein.

Abstract: The present invention provides an effective method for fractionating rubber particles in natural rubber latex by particle size, and effective methods for transporting or preserving rubber particles. The present invention relates to a method for fractionating rubber particles in natural rubber latex by particle size, the method including centrifuging natural rubber latex in at least four stages at forces of 800 to 3,000×g, 6,500 to 10,000×g, 17,000 to 22,000×g, and 40,000 to 60,000×g to fractionate rubber particles. The present invention also relates to methods for transporting or preserving rubber particles, the methods including the steps of adding a buffer solution and an antioxidant to natural rubber latex or rubber particles fractionated from natural rubber latex; and freezing a mixture prepared in the above step.

Abstract: An object of the present invention is to provide DNA which regulates the expression of miR-140, a reporter vector which contains the DNA, cells and animals into which the reporter vector is introduced and a screening system for drugs which control the expression of miR-140 and is also to contribute in the development of new therapeutic agents for cartilage diseases such as osteoarthritis and intervertebral disk degeneration using the screening system. The DNA sequence according to the present invention is able to express any gene in a site where miR-140 is expressed and, in addition, it is also able to be utilized for screening a drug which regulates the expression of miR-140. Moreover, the drug that is selected by the screening system of the present invention is expected as a therapeutic agent for cartilage diseases accompanied by abnormality of cartilage.

Abstract: An X-ray diagnosis apparatus detects X-rays output from an X-ray source and transmitted through a subject, and generates images of the inside of the subject, and comprises a detector, an X-ray intensity distribution data generator, and an entrance dose distribution data generator. The detector detects the intensity of the X-rays output from the X-ray source. The X-ray intensity distribution data generator generates X-ray intensity distribution data showing the X-ray intensity for each of a plurality of subdomains of an X-ray irradiation field from the X-ray source based on the detection outcome by the detector. The entrance dose distribution data generator generates entrance dose distribution data showing the dose of X-rays output from the X-ray source and irradiated onto the subject, based on the X-ray intensity distribution data.

Abstract: Provided is a method for producing rubber particles with a reduced coagulation tendency. The present invention relates to a method for producing rubber particles with a reduced coagulation tendency, the method including a step of performing protein synthesis in the presence of both rubber particles and a cell-free protein synthesis solution containing an mRNA coding for a rubber elongation factor (REF) family protein to bind the REF family protein to the rubber particles.

Abstract: A magnetic resonance imaging apparatus according to the invention includes a magnet device that generates a static magnetic field and a gradient magnetic field in an imaging space, a top plate that is provided to freely travel on a bed and sends an object lying thereon into the imaging space, a top plate reception member that is disposed inside the imaging space and has a traveling surface of the top plate, a top plate support column that supports the top plate reception member, and a top plate support pedestal that supports a lower end of the top plate support column, in which the top plate support pedestal is provided on a floor surface on which the magnet device is provided, via a magnet support leg, and is provided so that a movement in a direction along at least the floor surface is restricted to the magnet support leg.

Abstract: The present invention provides an active energy ray-curable resin composition containing: (A) a monofunctional ethylenically unsaturated monomer free of urethane groups; (B) a polyfunctional ethylenically unsaturated monomer free of urethane groups; (C) a urethane group-containing ethylenically unsaturated monomer; (D) a photopolymerization initiator; (E) a polymerization inhibitor; and (F) a surfactant, wherein relative to the total weight of (A), (B), (C), (D), (E), and (F), the weight ratio of (A) is 45 to 90% by weight, the weight ratio of (B) is 3 to 25% by weight, the weight ratio of (C) is 3 to 35% by weight, the weight ratio of (D) is 0.1 to 10% by weight, the weight ratio of (E) is 0.01 to 5% by weight, and the weight ratio of (F) is 0.1 to 10% by weight, and the resin composition has a surface tension of 20 to 30 mN/m.

Abstract: It is intended to provide a novel azabicyclo compound which exhibits both HSP90 inhibitory activity and cell proliferation inhibitory effect. Specifically disclosed is a compound represented by the following general formula (I) or a salt thereof: wherein X1 represents CH or N; any one of X2, X3 and X4 represents N, and the others represent CH; any one or two of Y1, Y2, Y3 and Y4 represent C—R4, and the others are the same or different and represent CH or N; R1 represents an optionally substituted monocyclic or bicyclic unsaturated heterocyclic group having 1 to 4 heteroatoms selected from N, S and O; R2 represents an alkyl group having 1 to 6 carbon atoms, or the like; and R3 and R4 represent —CO—R5 or the like.

Abstract: An airbag device includes: an airbag; an inflator; a gas discharge state switching member; and a tether belt which is one example of a connecting member. The gas discharge state switching member is switched over from a gas discharge state to a gas non-discharge state by being pulled into the inside of the airbag. The tether belt connects the gas discharge state switching member and a portion of an inner peripheral portion of the airbag to each other. An arranged position of the gas discharge state switching member, a position where the tether belt is connected to the inner peripheral portion of the airbag, and a passing line of the tether belt are disposed at portions which avoid a portion of the airbag which comes into contact with an occupant in a regular posture state when the airbag receives the occupant.

Abstract: According to one embodiment, a holding apparatus includes an arcuated arm, a first roller, and a second roller. The arcuated arm is provided with a guide groove along the outer surface, has a hollow portion inside, and holds the X-ray generator and X-ray detector while making them squarely face each other. The first roller runs in the hollow portion in contact with the inner wall of the hollow portion on the outer surface side. The second roller runs in the guide groove while being fitted in the guide groove, and holds the arm together with the first roller so as to allow the arm to slide along the arcuated direction.

Abstract: According to one embodiment, an X-ray diagnostic apparatus includes a first arm, a second arm, an imaging system and a slide mechanism. The first arm rotates by a first rotating shaft and slides along with a first arc-like slide axis relatively to the first rotating shaft. The second arm rotates by a second rotating shaft fixed to the first arm and slides along with a second arc-like slide axis relatively to the second rotating shaft. The imaging system includes an X-ray generating part and an X-ray detector. The X-ray generating part and the X-ray detector are attached to the second arm. The slide mechanism slides the first arm along with the first slide axis. The slide mechanism is arranged at a position having an offset from the first rotating shaft.

Abstract: An airbag device includes: an airbag; an inflator; a gas discharge state switching member; and a tether belt which is one example of a connecting member. The gas discharge state switching member is switched over from a gas discharge state to a gas non-discharge state by being pulled into the inside of the airbag. The tether belt connects the gas discharge state switching member and a portion of an inner peripheral portion of the airbag to each other. An arranged position of the gas discharge state switching member, a position where the tether belt is connected to the inner peripheral portion of the airbag, and a passing line of the tether belt are disposed at portions which avoid a portion of the airbag which comes into contact with an occupant in a regular posture state when the airbag receives the occupant.