Patents by Inventor Scott A. Eastman

Scott A. Eastman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PATHOGEN TESTING SYSTEMS AND METHODS OF USE THEREOF
    Publication number: 20240061002
    Abstract: Provided herein are mobile systems for sample processing. In some aspects, provided herein are mobile systems for sample processing and methods of use thereof for detection of pathogens in biological samples.
    Type: Application
    Filed: January 5, 2022
    Publication date: February 22, 2024
    Inventors: Peter James Dailey, Richard McGregor Thayer, Laura Terese Mazzola, Paul Scott Eastman, Michael S. Urdea, Jesse Charles Darley, Ryan Lee Anton, Katherine Gail Mason, Sara Willoughby Berg-Love, Justin Daniel Chan, Russell Prince, Douglas Paul Barnes, Evan Alex Bunke, Jacob Emory Schepp, Douglas E. Seals, Alexandra A. Surasky-Ysasi, Angie Purvis, Christina Newman, Dawn Dudley, David O'Connor, Thomas Friedrich, Steven Carbone, Madalyn Gill, Brianna Mullins, Jay Warrick, Patrick McMinn, Dave Beebe, Ryan Shogren, Mitch Geiger, Franklin Zhong, Duane S. Juang, Terry D. Juang
  • Biomarkers and methods for assessing psoriatic arthritis disease activity
    Patent number: 11656227
    Abstract: Provided herein are biomarkers and methods for generating scores useful for assessing psoriatic arthritis (PsA) disease activity in subjects previously diagnosed with PsA. The invention also provides predictive model methods based on the biomarkers, as well as computer systems, software embodiments of the models for scoring and optionally classifying samples, and methods of recommending optimal therapeutic regimens.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: May 23, 2023
    Inventors: Eric Sasso, Paul Scott Eastman, Rebecca Bolce, Arthur Kavanaugh
  • Load bearing member for an elevator system having an elastomer and phosphonate blended bonding agent
    Patent number: 11518652
    Abstract: A belt for an elevator system is provided having a core and an elastomeric sheath positioned over the core. An elastomer and phosphonate blended bonding agent adheres the core to the sheath.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: December 6, 2022
    Assignee: OTIS ELEVATOR COMPANY
    Inventors: Georgios S. Zafiris, Scott A. Eastman
  • Biomarkers and methods for measuring and monitoring axial spondyloarthritis activity
    Patent number: 11493512
    Abstract: Biomarkers useful for diagnosing and assessing inflammatory disease activity, for prediction of risk for progressive spinal and joint damage, in particular for axial spondyloarthritis (axSpA) and ankylosing spondylitis (AS), and for generating a dataset are provided, along with kits for measuring expression of the biomarkers. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples.
    Type: Grant
    Filed: December 9, 2016
    Date of Patent: November 8, 2022
    Assignee: Laboratory Corporation of America Holdings
    Inventors: Paul Scott Eastman, Eric Sasso
  • Biomarkers and methods for assessing response to inflammatory disease therapy
    Patent number: 11402378
    Abstract: Provided herein are methods for assessing response to inflammatory disease therapy. The methods include performing immunoassays to generate scores based on quantitative data for expression of biomarkers relating to inflammatory biomarkers to assess disease activity in inflammatory diseases, e.g., rheumatoid arthritis. Also provided are uses of inflammatory biomarkers for guiding treatment decisions.
    Type: Grant
    Filed: October 18, 2018
    Date of Patent: August 2, 2022
    Assignee: Laboratory Corporation of America Holdings
    Inventors: Paul Scott Eastman, William Manning
  • BIOMARKERS AND METHODS FOR ASSESSING PSORIATIC ARTHRITIS DISEASE ACTIVITY
    Publication number: 20220214341
    Abstract: Provided herein are biomarkers and methods for generating scores useful for assessing psoriatic arthritis (PsA) disease activity in subjects previously diagnosed with PsA. The invention also provides predictive model methods based on the biomarkers, as well as computer systems, software embodiments of the models for scoring and optionally classifying samples, and methods of recommending optimal therapeutic regimens.
    Type: Application
    Filed: September 9, 2021
    Publication date: July 7, 2022
    Inventors: Eric Sasso, Paul Scott Eastman, Rebecca Bolce, Arthur Kavanaugh
  • BIOMARKERS AND METHODS FOR ASSESSING RESPONSE TO INFLAMMATORY DISEASE THERAPY
    Publication number: 20220057395
    Abstract: Provided herein are methods for assessing response to inflammatory disease therapy. The methods include performing immunoassays to generate scores based on quantitative data for expression of biomarkers relating to inflammatory biomarkers to assess disease activity in inflammatory diseases, e.g., rheumatoid arthritis. Also provided are uses of inflammatory biomarkers for guiding treatment decisions.
    Type: Application
    Filed: September 1, 2021
    Publication date: February 24, 2022
    Applicant: Laboratory Corporation of America Holdings
    Inventors: Paul Scott Eastman, William Manning
  • BIOMARKERS AND METHODS FOR MEASURING AND MONITORING AXIAL SPONDYLOARTHRITIS ACTIVITY
    Publication number: 20220057394
    Abstract: Biomarkers useful for diagnosing and assessing inflammatory disease activity, for prediction of risk for progressive spinal and joint damage, in particular for axial spondyloarthritis (axSpA) and ankylosing spondylitis (AS), and for generating a dataset are provided, along with kits for measuring expression of the biomarkers. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples.
    Type: Application
    Filed: September 1, 2021
    Publication date: February 24, 2022
    Applicant: Laboratory Corporation of America Holdings
    Inventors: Paul Scott Eastman, Eric Sasso
  • LOAD BEARING MEMBER FOR AN ELEVATOR SYSTEM HAVING AN ELASTOMER AND PHOSPHONATE BLENDED BONDING AGENT
    Publication number: 20210198082
    Abstract: A belt for an elevator system is provided having a core and an elastomeric sheath positioned over the core. An elastomer and phosphonate blended bonding agent adheres the core to the sheath.
    Type: Application
    Filed: March 12, 2021
    Publication date: July 1, 2021
    Inventors: Georgios S. Zafiris, Scott A. Eastman
  • Material and processes for additively manufacturing one or more parts
    Patent number: 11033961
    Abstract: Material is provided for forming a part using a manufacturing system. The material includes a plurality of discrete particles. Each of the particles includes a metal powder core encapsulated by a non-metal coating. At least the cores of the particles are adapted to be solidified together by the manufacturing system to form the part.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: June 15, 2021
    Assignee: Raytheon Technologies Corporation
    Inventors: Ying She, Aaron T. Nardi, Zissis A. Dardas, Michael A. Klecka, Scott A. Eastman
  • Load bearing member for an elevator system having an elastomer and phosphonate blended bonding agent
    Patent number: 10974929
    Abstract: A belt for an elevator system is provided having a core and an elastomeric sheath positioned over the core. An elastomer and phosphonate blended bonding agent adheres the core to the sheath.
    Type: Grant
    Filed: November 6, 2017
    Date of Patent: April 13, 2021
    Assignee: OTIS ELEVATOR COMPANY
    Inventors: Georgios S. Zafiris, Scott A. Eastman
  • BIOMARKERS AND METHODS FOR MEASURING AND MONITORING JUVENILE IDIOPATHIC ARTHRITIS ACTIVITY
    Publication number: 20200300853
    Abstract: Biomarkers useful for assessing inflammatory disease or flare activity, in particular in juvenile idiopathic arthritis, are provided, along with kits for measuring expression of the biomarkers. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples.
    Type: Application
    Filed: June 9, 2020
    Publication date: September 24, 2020
    Applicant: CRESCENDO BIOSCIENCE, INC.
    Inventors: Scott Eastman, Eric Sasso
  • ADJUSTED MULTI-BIOMARKER DISEASE ACTIVITY SCORE FOR INFLAMMATORY DISEASE ASSESSMENT
    Publication number: 20200249243
    Abstract: Provided herein are methods for assessing response to inflammatory disease therapy. The methods include performing immunoassays to generate scores based on quantitative data for expression of biomarkers relating to inflammatory biomarkers to assess disease activity in inflammatory diseases, e.g., rheumatoid arthritis. Also provided are methods of adjusting disease activity scores to account for variables that can influence such scores.
    Type: Application
    Filed: July 30, 2018
    Publication date: August 6, 2020
    Applicant: MYRIAD GENETICS, INC.
    Inventors: Ching Chang HWANG, David CHERNOFF, Alexander GUTIN, Darl FLAKE, Jerry LANCHBURY, Paul Scott EASTMAN, Eric SASSO
  • Biomarkers and methods for measuring and monitoring juvenile idiopathic arthritis activity
    Patent number: 10718765
    Abstract: Biomarkers useful for assessing inflammatory disease or flare activity, in particular in juvenile idiopathic arthritis, are provided, along with kits for measuring expression of the biomarkers. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: July 21, 2020
    Assignee: CRESCENDO BIOSCIENCE, INC.
    Inventors: Scott Eastman, Eric Sasso
  • Load bearing member for an elevator system having a metalized polymer coating
    Patent number: 10472210
    Abstract: A belt for an elevator system is provided. The belt includes a plurality of tension members arranged along a belt width. A jacket material at least partially encapsulates the plurality of tension members. The jacket material includes a traction surface and a back surface opposite the traction surface together defining a belt thickness therebetween. The jacket material also includes two end surfaces extending between the traction surface and the back surface and defining the belt width therebetween. A metalized polymer coating layer is disposed over at least one of the two end surfaces.
    Type: Grant
    Filed: November 7, 2016
    Date of Patent: November 12, 2019
    Assignee: OTIS ELEVATOR COMPANY
    Inventors: Georgios S. Zafiris, Paul Papas, Daniel A. Mosher, Scott A. Eastman, Zhongfen Ding, Brad Guilani
  • BIOMARKERS AND METHODS FOR ASSESSING RESPONSE TO INFLAMMATORY DISEASE THERAPY
    Publication number: 20190049443
    Abstract: Provided herein are methods for assessing response to inflammatory disease therapy. The methods include performing immunoassays to generate scores based on quantitative data for expression of biomarkers relating to inflammatory biomarkers to assess disease activity in inflammatory diseases, e.g., rheumatoid arthritis. Also provided are uses of inflammatory biomarkers for guiding treatment decisions.
    Type: Application
    Filed: October 18, 2018
    Publication date: February 14, 2019
    Inventors: Paul Scott Eastman, William Manning
  • BIOMARKERS AND METHODS FOR ASSESSING PSORIATIC ARTHRITIS DISEASE ACTIVITY
    Publication number: 20180217143
    Abstract: Provided herein are biomarkers and methods for generating scores useful for assessing psoriatic arthritis (PsA) disease activity in subjects previously diagnosed with PsA. The invention also provides predictive model methods based on the biomarkers, as well as computer systems, software embodiments of the models for scoring and optionally classifying samples, and methods of recommending optimal therapeutic regimens.
    Type: Application
    Filed: March 28, 2018
    Publication date: August 2, 2018
    Inventors: Eric Sasso, Paul Scott Eastman, Rebecca Bolce, Arthur Kavanaugh
  • LOAD BEARING MEMBER FOR AN ELEVATOR SYSTEM HAVING A METALIZED POLYMER COATING
    Publication number: 20180127239
    Abstract: A belt for an elevator system is provided. The belt includes a plurality of tension members arranged along a belt width. A jacket material at least partially encapsulates the plurality of tension members. The jacket material includes a traction surface and a back surface opposite the traction surface together defining a belt thickness therebetween. The jacket material also includes two end surfaces extending between the traction surface and the back surface and defining the belt width therebetween. A metalized polymer coating layer is disposed over at least one of the two end surfaces.
    Type: Application
    Filed: November 7, 2016
    Publication date: May 10, 2018
    Inventors: Georgios S. Zafiris, Paul Papas, Daniel A. Mosher, Scott A. Eastman, Zhongfen Ding, Brad Guilani
  • LOAD BEARING MEMBER FOR AN ELEVATOR SYSTEM HAVING AN ELASTOMER AND PHOSPHONATE BLENDED BONDING AGENT
    Publication number: 20180127240
    Abstract: A belt for an elevator system is provided having a core and an elastomeric sheath positioned over the core. An elastomer and phosphonate blended bonding agent adheres the core to the sheath.
    Type: Application
    Filed: November 6, 2017
    Publication date: May 10, 2018
    Inventors: Georgios S. Zafiris, Scott A. Eastman
  • BIOMARKERS AND METHODS FOR MEASURING AND MONITORING AXIAL SPONDYLOARTHRITIS ACTIVITY
    Publication number: 20170097347
    Abstract: Biomarkers useful for diagnosing and assessing inflammatory disease activity, for prediction of risk for progressive spinal and joint damage, in particular for axial spondyloarthritis (axSpA) and ankylosing spondylitis (AS), and for generating a dataset are provided, along with kits for measuring expression of the biomarkers. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples.
    Type: Application
    Filed: December 9, 2016
    Publication date: April 6, 2017
    Inventors: Paul Scott Eastman, Eric Sasso