Abstract: Material is provided for forming a part using a manufacturing system. The material includes a plurality of discrete particles. Each of the particles includes a metal powder core encapsulated by a non-metal coating. At least the cores of the particles are adapted to be solidified together by the manufacturing system to form the part.

Abstract: Biomarkers useful for assessing inflammatory disease or flare activity, in particular in juvenile idiopathic arthritis, are provided, along with kits for measuring expression of the biomarkers. The invention also provides predictive models, based on the biomarkers, as well as computer systems, and software embodiments of the models for scoring and optionally classifying samples.

Abstract: An abradable seal material comprises: a polyimide foam matrix; and a thermal conductivity-enhancing filler in the matrix.

Abstract: Fall away arrow rests for archery bows. The rests have an arm with an arrow-supporting feature and an arm-associated axle which pivots the arm to displace the arrow-supporting feature between a first, arrow-loading position and a second, more elevated, arrow-launching position. The arrow support arm can be adjusted vertically, laterally, and in fore-and-aft directions relative to a riser or other rigid bow component on which the rest is mounted. One or more dampers can be advantageously attached to arrow rest structural members to reduce shock and vibrations, including noise, as the arrow support arm displaces the arrow-supporting feature between its first and second positions, especially as an arrow is launched from the bow.

Abstract: Quiet, lightweight, well-balanced, forgiving, and accurate compound archery bows which have significantly reduced vibration and bow jump. The limbs and cams of these bows can be removed and replaced without a bow press, and the limbs of the bows are functional (active) over essentially their entire length and allow one to obtain equivalent performance from a more compact and lighter bow. The bow limbs may be leverage locked in articulated limb pockets. The limb butts extend forward well beyond the front of the riser. This eliminates limb length and limb angle as major factors in determining brace height, allowing one to choose a riser style and limb length which optimize arrow speed and bow stabilization. Novel adjustment mechanisms allow one to easily adjust the poundage or poundage and brace height of the bow. Vibration isolation systems may be employed to isolate the bow riser from the limb pockets.

Abstract: The combination of an optical sight and an attachable/detachable adjustable range sighting device accessory, in which the optical sight comprises a support and an array of fixedly positioned fiber optics sighting devices carried by the support; and the accessory comprising a displaceable fiber optics sighting device and a mechanism for shifting the position of the displaceable fiber optics device relative to the array of fixedly positioned sighting devices.

Abstract: An optical bow sight which can be accessorized with an adjustable range sighting pin or torque and cant compensation or both of these features, but is fully functional without either accessory. The optical sight has a shrouded array of fiber optics sight pins which are removable from the sight housing with their support as a single unit. The sight pins are clad in a metallic glass because of the corrosion resistance of such materials. Light collected over a wide field falls on segments of the sight pin fibers coiled in the housing of the optical unit or falls on a trap which redirects the light onto the fiber segments. A lens may optionally be employed to promote the collection of ambient light, and a shutter or variable size aperture may be provided to control the light reaching the sight pin fibers.

Abstract: Control beads are disclosed that allow for improved quantitation of analytes in multiplexed bead assays. The control beads have a range of concentrations of calibration moieties that provide for the preparation of a titration curve. The titration curve can be used to quantify the concentration of the analytes. The titration curve can be used to correlate the signal obtained from a bead with the concentration (or absolute number of molecules) of the analyte bound to the bead.

Abstract: The invention provides methods, compositions, and kits for multiplex fractionation of proteins in a sample. Protein-binding molecules, such as small epitope antibodies or small epitope aptamers, are used for multiplex fractionation of proteins in a protein containing sample. Detection of fractionated proteins may be used for characterization of proteins in a sample in applications such as expression profiling, identification and/or quantification of proteins in a sample, and identification or detection of biomarkers.

Abstract: Control beads are disclosed that allow for improved quantitation of analytes in multiplexed bead assays. The control beads have a range of concentrations of calibration moieties that provide for the preparation of a titration curve. The titration curve can be used to quantify the concentration of the analytes. The titration curve can be used to correlate the signal obtained from a bead with the concentration (or absolute number of molecules) of the analyte bound to the bead.

Abstract: Quiet, lightweight, well-balanced, forgiving, and accurate compound archery bows which have significantly reduced vibration and bow jump. The limbs and cams of these bows can be removed and replaced without a bow press, and the limbs of the bows are functional (active) over essentially their entire length and allow one to obtain equivalent performance from a more compact and lighter bow. The bow limbs may be leverage locked in articulated limb pockets. The limb butts extend forward well beyond the front of the riser. This eliminates limb length and limb angle as major factors in determining brace height, allowing one to choose a riser style and limb length which optimize arrow speed and bow stabilization. Novel adjustment mechanisms allow one to easily adjust the poundage or poundage and brace height of the bow. Vibration isolation systems may be employed to isolate the bow riser from the limb pockets.

Abstract: An optical bow sight which can be accessorized with an adjustable range sighting pin or torque and cant compensation or both of these features, but is fully functional without either accessory. The optical sight has a shrouded array of fiber optics sight pins which are removable from the sight housing with their support as a single unit. The sight pins are clad in a metallic glass because of the corrosion resistance of such materials. Light collected over a wide field falls on segments of the sight pin fibers coiled in the housing of the optical unit or falls on a trap which redirects the light onto the fiber segments. A lens may optionally be employed to promote the collection of ambient light, and a shutter or variable size aperture may be provided to control the light reaching the sight pin fibers.

Abstract: Fall away arrow rests for archery bows. The rests have an arm with an arrow-supporting feature and an arm-associated axle which pivots the arm to displace the arrow-supporting feature between a first, arrow-loading position and a second, more elevated, arrow-launching position. The arrow support arm can be adjusted vertically, laterally, and in fore-and-aft directions relative to a riser or other rigid bow component on which the rest is mounted. Radial arms rotatable with the axle and connectable to a buss cable or cable slide by a flexible link rotate the arm to elevate the arrow-supporting feature to its arrow-launching when the bow is drawn and offer further adjustment of the arrow rest operation. A coil spring installed in an axle housing returns the arrow-supporting feature to its first, loading position concomitantly with arrow launch, moving the support out of the path the arrow travels as it leaves the bow.

Abstract: The invention provides methods, compositions, and kits for multiplex fractionation of proteins in a sample. Protein-binding molecules, such as small epitope antibodies or small epitope aptamers, are used for multiplex fractionation of proteins in a protein containing sample. Detection of fractionated proteins may be used for characterization of proteins in a sample in applications such as expression profiling, identification and/or quantification of proteins in a sample, and identification or detection of biomarkers.

Abstract: Control beads are disclosed that allow for improved quantitation of analytes in multiplexed bead assays. The control beads have a range of concentrations of calibration moieties that provide for the preparation of a titration curve. The titration curve can be used to quantify the concentration of the analytes. The titration curve can be used to correlate the signal obtained from a bead with the concentration (or absolute number of molecules) of the analyte bound to the bead.

Abstract: The invention includes methods of detecting and measuring the amount of one or more species of bcr-abl spliced mRNA present in the sample, following nucleic acid amplification.

Abstract: A fluid containment fence apparatus provides a border around the perimeter of an area to be potted on one or both sides of a circuit board. First, or first and second (top and bottom), containment walls are secured in place using interlocking elements integral to the walls such that no external fasteners are needed. The interlocking elements permit snug adhesion of the fence to the board even when the board has variations in thickness. The interlocking elements extend through and interlock through engagement with another fence or the board. The size of the holes is minimized. As a result, a minimum amount of board space is occupied by the fence, and the overall size of the board is maintained.

Abstract: A fluid containment fence apparatus provides a border around the perimeter of an area to be potted on one or both sides of the board. First, or first and second and second (top and bottom), containment walls are secured in place using interlocking elements integral to the walls such that no external fasteners are needed. The interlocking elements permit snug adhesion of the fence to the board even when the board has variations in thickness. The interlocking elements extend through and interlock through engagement with another fence or the board. The size of the holes is minimized. As a result, a minimum amount of board space is occupied by the fence, and the overall size of the board is maintained. A potting fluid containment fence for a board having components to be encased in a potting fluid includes a first wall. The components to be encased are arranged on an upper face of the board, at least.