Abstract: A one-piece molded funnel for transferring granular material or liquids into a container. The molded funnel includes a main body having an open interior to receive the material or liquid. A pouring neck extends from the main body and has a first diameter that is smaller than the open interior. A support collar is formed as part of the funnel and is designed to support the funnel on the storage container. The support collar has a second diameter that is larger than the first diameter of the pouring neck to create a receiving channel between the pouring neck and the support collar. During use of the funnel, the upper end of the storage container is received in the receiving channel and the pouring neck extends into the upper end of the storage container. The support collar can include different diameter portions or expansion gaps to accommodate different sized storage containers.

Abstract: Various embodiments of the invention disclosed herein provide techniques for frame-accurate navigation of a media file. A multi-pass encoding application executing on a media content server encodes a set of file-based images associated with a media file using a first set of encoding parameters to generate a first encoded media file. The multi-pass encoding application encodes the first encoded media file using a second set of encoding parameters to generate a second encoded media file. The first encoded media file and second encoded media file are stored on the media content server and/or or other media content servers. Content delivery applications executing on these media content servers receive a request associated with the media file from a web browsing application, determine a type of the web browsing application, and transmit either the first encoded media file or the second encoded media file based on the type of web browsing application.

Abstract: Various embodiments of the invention disclosed herein provide techniques for frame-accurate navigation of a media file. A multi-pass encoding application executing on a media content server encodes a set of file-based images associated with a media file using a first set of encoding parameters to generate a first encoded media file. The multi-pass encoding application encodes the first encoded media file using a second set of encoding parameters to generate a second encoded media file. The first encoded media file and second encoded media file are stored on the media content server and/or or other media content servers. Content delivery applications executing on these media content servers receive a request associated with the media file from a web browsing application, determine a type of the web browsing application, and transmit either the first encoded media file or the second encoded media file based on the type of web browsing application.

Abstract: An automated production system generates and shares digital data associated with a cinematic feature. The automated production system includes a collection of different modules which correspond to different stages in a production pipeline. Each module generates and stores portions of the digital data and also generates and stores associations between portions of that data. Various modules then perform data analytics across multiple associated portions of digital data to determine sources of production inefficiency. Thus, the automated production system allows a production studio to more efficiently generate a feature by mitigating or eliminating specific technological inefficiencies that arise during production of the feature.

Abstract: An automated production system generates and shares digital data associated with a cinematic feature. The automated production system includes a collection of different modules which correspond to different stages in a production pipeline. Each module generates and stores portions of the digital data and also generates and stores associations between portions of that data. Various modules then perform data analytics across multiple associated portions of digital data to determine sources of production inefficiency. Thus, the automated production system allows a production studio to more efficiently generate a feature by mitigating or eliminating specific technological inefficiencies that arise during production of the feature.

Abstract: Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.

Abstract: Described herein are compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein G1, L1, R2, R3, n, p, Ar1, and Ar2 are defined in the description. Methods of making said compounds, and compositions comprising said compounds which are useful for inhibiting kinases such as IGF-1R are also disclosed.

Abstract: Described herein are compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein L1, R1, R2, R3, R4, R5, and m are defined in the description. Methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as IGF-1R are also disclosed.

Abstract: The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein G1, R2, R3, R4, R5, n, p, q, Ar1, and Ar2 are defined in the description. The present invention relates also to methods of making said compounds, and compositions comprising said compounds which are useful for inhibiting kinases such as IGF-1R.

Abstract: Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.

Abstract: Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.

Abstract: Described herein are compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein G1, L1, R2, R3, n, p, Ar1, and Ar2 are defined in the description. Methods of making said compounds, and compositions comprising said compounds which are useful for inhibiting kinases such as IGF-1R are also disclosed.

Abstract: Described herein are compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein L1, R1, R2, R3, R4, R5, and m are defined in the description. Methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as IGF-1R are also disclosed.

Abstract: The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein G1, R2, R3, R4, R5, n, p, q, Ar1, and Ar2 are defined in the description. The present invention relates also to methods of making said compounds, and compositions comprising said compounds which are useful for inhibiting kinases such as IGF-1R.

Abstract: Compounds of formula (25) that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.

Abstract: Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.

Abstract: Compounds having methionine aminopeptidase-2 inhibitory (MetAP2) are described. Also described are pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, methods of inhibiting angiogenesis, and methods of treating cancer.

Abstract: Compounds having methionine aminopeptidase-2 inhibitory (MetAP2) are described. Also described are pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, methods of inhibiting angiogenesis, and methods of treating cancer.

Abstract: Compounds having methionine aminopeptidase-2 inhibitory (MetAP2) are described. Also described are pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, methods of inhibiting angiogenesis, and methods of treating cancer.

Abstract: Compounds having methionine aminopeptidase-2 inhibitory (MetAP2) are described. Also described are pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, methods of inhibiting angiogenesis, and methods of treating cancer.