Abstract: Described herein are compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein G1, L1, R2, R3, n, p, Ar1, and Ar2 are defined in the description. Methods of making said compounds, and compositions comprising said compounds which are useful for inhibiting kinases such as IGF-1R are also disclosed.

Abstract: Described herein are compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein L1, R1, R2, R3, R4, R5, and m are defined in the description. Methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as IGF-1R are also disclosed.

Abstract: An apparatus and method of refurbishing a modular work station or cubicle having a wall segment with at least one exterior surface and at least one horizontal load support that is connected to the wall segment so that it confronts the exterior surface. The apparatus includes one or more sheets of material that can be trimmed to the dimensions of the exterior surface and which are thin enough so that they are able to be inserted between a load support (such as a desk top, tack board, shelf, tool rail, cabinet, or the like) and the external surface. The one or more sheets can be penetrable (tackable), paramagnetic, and/or capable of use with wet or dry markers. The one or more sheets may also be provided with a finishing layer of woven material or fabric and can be fire resistant and/or have acoustical dampening properties.

Abstract: The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein G1, R2, R3, R4, R5, n, p, q, Ar1, and Ar2 are defined in the description. The present invention relates also to methods of making said compounds, and compositions comprising said compounds which are useful for inhibiting kinases such as IGF-1R.

Abstract: Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.

Abstract: Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.

Abstract: There is provided a method for optimizing a data backup. The method comprising determining a backup project size, the backup project size identifying the quantity of data to be backed up; detecting available recording devices for transferring the data backup to storage media; receiving an input corresponding to at least one user specified optimization variable, wherein the at least one user specified optimization variable comprises an upper limit on the length of each of the calculated plurality of data streams; utilizing the at least one user specified optimization variable to calculate a plurality of data streams for performing the data backup; and assigning subsets of the plurality of data streams to the available recording devices to optimize the data backup.

Abstract: The present invention relates to compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein G1, R2, R3, R4, R5, n, p, q, Ar1, and Ar2 are defined in the description. The present invention relates also to methods of making said compounds, and compositions comprising said compounds which are useful for inhibiting kinases such as IGF-1R.

Abstract: Described herein are compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein G1, L1, R2, R3, n, p, Ar1, and Ar2 are defined in the description. Methods of making said compounds, and compositions comprising said compounds which are useful for inhibiting kinases such as IGF-1R are also disclosed.

Abstract: Described herein are compounds of formula (I) or pharmaceutical acceptable salts or solvates thereof, wherein L1, R1, R2, R3, R4, R5, and m are defined in the description. Methods of making said compounds, and compositions containing said compounds which are useful for inhibiting kinases such as IGF-1R are also disclosed.

Abstract: A multi-substrate sheet for forming an at least partially open mesh fabric bag using a form, fill and seal machine and a bag formed of this sheet are provided. The sheet includes at least one strip formed of an open mesh polymeric fabric and at least one strip formed of a polymeric film. The fabric and film strips are secured to one another to form a web that can be formed into a roll and utilized with a form, fill and seal machine. The bag resulting from the processing of the web by the machine includes a substantial open mesh fabric portion to provide adequate ventilation to the product positioned within the bag and a printable film portion.

Abstract: Compounds of formula (25) that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.

Abstract: Hockey Shooting and Return System Training Devise used by hockey players which provides a very time and space efficient method for practicing ones shot. It is efficient for it returns the shot hockey puck back to the shooter relying only on the speed of the puck and the geometry of the return chute to accomplish this. In addition, the devise records and displays the current shot speed, and stores data of shots, so additional statistical data can be later viewed. The devise can be used for on ice training, and also for off ice training.

Abstract: There is provided a method for optimizing a data backup. The method comprising determining a backup project size, the backup project size identifying the quantity of data to be backed up; detecting available recording devices for transferring the data backup to storage media; receiving an input corresponding to at least one user specified optimization variable, wherein the at least one user specified optimization variable comprises an upper limit on the length of each of the calculated plurality of data streams; utilizing the at least one user specified optimization variable to calculate a plurality of data streams for performing the data backup; and assigning subsets of the plurality of data streams to the available recording devices to optimize the data backup.

Abstract: A multi-substrate sheet for forming an at least partially open mesh fabric bag using a form, fill and seal machine and a bag formed of this sheet are provided. The sheet includes at least one strip formed of an open mesh polymeric fabric and at least one strip formed of a polymeric film. The fabric and film strips are secured to one another to form a web that can be formed into a roll and utilized with a form, fill and seal machine. The bag resulting from the processing of the web by the machine includes a substantial open mesh fabric portion to provide adequate ventilation to the product positioned within the bag and a printable film portion.

Abstract: Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.

Abstract: Compounds having methionine aminopeptidase-2 inhibitory (MetAP2) are described. Also described are pharmaceutical compositions comprising the compounds, methods of treatment using the compounds, methods of inhibiting angiogenesis, and methods of treating cancer.

Abstract: An electronic controller for a vehicle leveling system comprises an extend-enable switch, a retract-enable switch, an all-activate switch, and at least one group-activate switch. It is configured to generate an all-extend electronic signal upon coordinated actuation of the extend-enable switch and the all-activate switch, an all-retract electronic signal upon coordinated actuation of the retract-enable switch and the all-activate switch, a group-extend electronic signal upon coordinated actuation of the extend-enable switch and the group-activate switch, and a group-retract electronic signal upon coordinated actuation of the retract-enable switch and the group-activate switch. Vehicle leveling systems having the electronic controller further include a plurality of jacks operably controlled by the electronic controller and a power system.

Abstract: Compounds that inhibit protein kinases, compositions containing the compounds and methods of treating diseases using the compounds are disclosed.

Abstract: A multi-substrate sheet for forming an at least partially open mesh fabric bag using a form, fill and seal machine and a bag formed of this sheet are provided. The sheet includes at least one strip formed of an open mesh polymeric fabric and at least one strip formed of a polymeric film. The fabric and film strips are secured to one another to form a web that can be formed into a roll and utilized with a form, fill and seal machine. The bag resulting from the processing of the web by the machine includes a substantial open mesh fabric portion to provide adequate ventilation to the product positioned within the bag and a printable film portion.