Patents by Inventor Scott A. Small

Scott A. Small has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20090253779
    Abstract: This invention provides a method for increasing the expression of RbAp48 protein in a eukaryotic cell comprising introducing into the cell an agent which specifically increases the expression of RbAp48 protein in the cell. This invention also provides a method for treating a subject afflicted with age-related memory decline comprising administering to the subject a therapeutically effective amount of an agent which specifically increases the expression of RbAp48 protein in the cells of the subject's brain. This invention further provides a method for determining whether an agent causes an increase in the expression of RbAp48 protein. Finally, this invention provides a method for determining whether an agent causes an increase in the activity of RbAp48 protein.
    Type: Application
    Filed: October 19, 2006
    Publication date: October 8, 2009
    Inventor: Scott A. Small
  • Publication number: 20090246145
    Abstract: This invention provides a method for treating a mammalian subject afflicted with a disorder associated with reduced neurogenesis in the subject's hippocampal dentate gyrus which comprises administering to the subject a therapeutically effective amount of a compound which increases cerebral blood volume in the subject's hippocampal dentate gyrus by a percentage greater than that by which it increases the cerebral blood volume in the subject's hippocampal CA1 region, thereby treating the subject.
    Type: Application
    Filed: November 14, 2006
    Publication date: October 1, 2009
    Inventor: Scott A. Small
  • Publication number: 20090005711
    Abstract: A system and method for opening the blood-brain barrier in the brain of a subject is disclosed. In some embodiments, a region of the brain of a subject is targeted for opening; and a focused ultrasound beam is applied through the skull of the subject to the targeted region to open the blood-brain barrier in the brain of the subject.
    Type: Application
    Filed: March 19, 2008
    Publication date: January 1, 2009
    Inventors: Elisa E. Konofagou, James J. Choi, Mathieu Pernot, Scott A. Small