Patents by Inventor Scott A. Stevenson
Scott A. Stevenson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11869187Abstract: Risk prediction models are trained and deployed to analyze images, such as computed tomography scans, for predicting future risk of lung cancer for one or more subjects. Individual risk prediction models are separately trained on nodule-specific and non-nodule specific features such that each risk prediction model can predict future risk of lung cancer across different time periods (e.g., 1 year, 3 years, or 5 years). Such risk prediction models are useful for developing preventive therapies for lung cancer by enabling clinical trial enrichment.Type: GrantFiled: March 10, 2023Date of Patent: January 9, 2024Assignee: Johnson & Johnson Enterprise Innovation Inc.Inventors: George R. Washko, Jr., Christopher Scott Stevenson, Samuel Yoffe Ash, Raul San Jose Estepar, Matthew David Mailman
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Publication number: 20240005502Abstract: Disclosed herein are methods for determining a subject level risk of metastatic cancer involving the training and/or deployment of models to determine 1) a lymph node level risk of individual lymph node involvement and/or 2) a subject level risk of lymph node involvement. Thus, the methods can identify patients who are high or low risk for having nodal disease and optionally enable the guided intervention of cancer patients, for example, via treatment.Type: ApplicationFiled: November 30, 2021Publication date: January 4, 2024Inventors: George R. Washko, JR., Raul San Jose Estepar, Charles Matthew Kinsey, Christopher Scott Stevenson
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Publication number: 20230215004Abstract: Risk prediction models are trained and deployed to analyze images, such as computed tomography scans, for predicting future risk of lung cancer for one or more subjects. Individual risk prediction models are separately trained on nodule-specific and non-nodule specific features such that each risk prediction model can predict future risk of lung cancer across different time periods (e.g., 1 year, 3 years, or 5 years). Such risk prediction models are useful for developing preventive therapies for lung cancer by enabling clinical trial enrichment.Type: ApplicationFiled: March 10, 2023Publication date: July 6, 2023Inventors: George R. Washko, JR., Christopher Scott Stevenson, Samuel Yoffe Ash, Raul San Jose Estepar, Matthew David Mailman
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Patent number: 11640661Abstract: Risk prediction models are trained and deployed to analyze images, such as computed tomography scans, for predicting future risk of lung cancer for one or more subjects. Individual risk prediction models are separately trained on nodule-specific and non-nodule specific features such that each risk prediction model can predict future risk of lung cancer across different time periods (e.g., 1 year, 3 years, or 5 years). Such risk prediction models are useful for developing preventive therapies for lung cancer by enabling clinical trial enrichment.Type: GrantFiled: January 15, 2021Date of Patent: May 2, 2023Assignee: Johnson & Johnson Enterprise Innovation Inc.Inventors: George R. Washko, Jr., Christopher Scott Stevenson, Samuel Yoffe Ash, Raul San Jose Estepar, Matthew David Mailman
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Patent number: 11603344Abstract: A process for producing methyl tert-butyl ether (MTBE) comprising introducing a butane feed stream (n-butane, i-butane) and hydrogen to a hydrogenolysis reactor comprising a hydrogenolysis catalyst to produce a hydrogenolysis product stream comprising hydrogen, methane, ethane, propane, i-butane, and optionally n-butane; separating the hydrogenolysis product stream into a first hydrogen-containing stream, an optional methane stream, a C2 to C3 gas stream (ethane, propane), and a butane stream (i-butane, optionally n-butane); feeding the butane stream to a dehydrogenation reactor to produce a dehydrogenation product stream, wherein the dehydrogenation reactor comprises a dehydrogenation catalyst, and wherein the dehydrogenation product stream comprises hydrogen, i-butane, and isobutylene; and feeding the dehydrogenation product stream and methanol to an etherification unit to produce an unreacted methanol stream, an unreacted isobutylene stream, and an MTBE stream.Type: GrantFiled: September 17, 2019Date of Patent: March 14, 2023Assignee: Sabic Global Technologies, B.V.Inventors: Dustin Fickel, Scott Stevenson, MyatNoeZin Myint, Heng Shou
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Publication number: 20230027734Abstract: Risk prediction models are trained and deployed to analyze images, such as computed tomography scans, for predicting risk of lung cancer (e.g., current or future risk of lung cancer) for one or more subjects. Individual risk prediction models are trained on nodule-specific and non-nodule specific features, including longitudinal nodule specific and longitudinal non-nodule specific features, such that each risk prediction model can predict risk of lung cancer across different time horizons. Such risk prediction models are useful for developing preventive therapies for lung cancer by enabling clinical trial enrichment.Type: ApplicationFiled: July 13, 2022Publication date: January 26, 2023Inventors: George R. Washko, JR., Christopher Scott Stevenson, Samuel Yoffe Ash, Raul San Jose Estepar, Matthew David Mailman
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Publication number: 20220126251Abstract: A chemical synthesis plant comprising: one or more reactors configured for producing, from one or more reactants, a process stream comprising at least one chemical product; a feed preparation system configured to prepare one or more feed streams comprising one or more of the one or more reactants for introduction into the one or more reactors; and/or a product purification system configured to separate the at least one chemical product from reaction byproducts, unreacted reactants, or a combination thereof within the process stream, wherein the chemical synthesis plant is configured such that a majority of the net energy needed for heating, cooling, compressing, or a combination thereof utilized via the one or more reactors, the feed preparation system, the product purification system, or a combination thereof is provided from a noncarbon based energy source, from a renewable energy source, and/or from electricity.Type: ApplicationFiled: January 14, 2020Publication date: April 28, 2022Applicant: SABIC Global Technologies B.V.Inventors: Scott STEVENSON, Andrew Mark WARD, Tim ABBOTT, Kenneth Francis LAWSON, Joseph William SCHROER, Michael Edward HUCKMAN, Arno OPRINS, Zhun ZHAO
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Publication number: 20220127209Abstract: An olefin synthesis plant comprising: a feed pretreatment section configured to pretreat a feed stream; a pyrolysis section comprising one or more pyrolysis reactors configured to crack hydrocarbons in the feed stream in the presence of a diluent to produce a cracked gas stream; a primary fractionation and compression section configured to provide heat recovery from and quenching of the cracked gas stream; remove a component from the cracked gas stream; and compress the cracked gas stream, thus providing a compressed cracked gas stream; and/or a product separation section configured to separate a product olefin stream from the compressed cracked gas stream, wherein the olefin synthesis plant is configured such that, relative to a conventional olefin synthesis plant, more of the energy and/or the net energy required by the olefin synthesis plant and/or one or more sections thereof, is provided by a non-carbon based and/or renewable energy source and/or electricity.Type: ApplicationFiled: January 14, 2020Publication date: April 28, 2022Applicant: SABIC Global Technologies B.V.Inventors: Andrew Mark WARD, Scott STEVENSON, Arno OPRINS, Zhun ZHAO, Tim ABBOTT, Kenneth Francis LAWSON, Joseph William SCHROER, Michael Edward HUCKMAN
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Publication number: 20220119269Abstract: An ammonia synthesis plant comprising: a feed pretreating section operable to pretreat a feed stream; a syngas generation section operable to reform the feed stream to produce a reformer product stream; a shift conversion section operable to subject the reformer product stream to the water gas shift reaction, to produce a shifted gas stream comprising more hydrogen than the reformer gas stream; a purification section operable to remove at least one component from the shifted gas stream, and provide an ammonia synthesis feed stream; and/or an ammonia synthesis section operable to produce ammonia from the ammonia synthesis feed stream, wherein the ammonia synthesis plant is configured such that, relative to a conventional ammonia synthesis plant, more of the energy required by the ammonia synthesis plant or one or more sections thereof is provided by a non-carbon based energy source, a renewable energy source, and/or electricity.Type: ApplicationFiled: January 14, 2020Publication date: April 21, 2022Applicant: SABIC Global Technologies B.V.Inventors: Michael Edward HUCKMAN, Scott STEVENSON, Andrew Mark WARD, Tim ABBOTT, Kenneth Francis LAWSON, Joseph William SCHROER, Zhun ZHAO, Arno OPRINS
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Publication number: 20220119252Abstract: A chemical synthesis plant comprising: one or more reactors configured for producing, from one or more reactants, a process stream comprising at least one chemical product; a feed preparation system configured to prepare one or more feed streams comprising one or more of the one or more reactants for introduction into the reactor; and/or a product purification system configured to separate the at least one chemical product from reaction byproducts, unreacted reactants, or a combination thereof within the process stream, wherein the chemical synthesis plant is configured such that a majority (e.g., greater than 50, 60, 70, 80, 90, or 100%) of the net energy needed for heating, cooling, compressing, or a combination thereof utilized via the one or more reactors, the feed preparation system, the product purification system, or a combination thereof is provided from an intermittent energy source (IES).Type: ApplicationFiled: January 14, 2020Publication date: April 21, 2022Applicant: SABIC Global Technologies B.V.Inventors: Scott STEVENSON, Andrew Mark WARD, Kenneth Francis LAWSON, Joseph William SCHROER, Michael Edward HUCKMAN, Zhun ZHAO
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Publication number: 20220119328Abstract: A methanol synthesis plant comprising: a feed pretreating section operable to pretreat a feed stream; a synthesis gas (syngas) generation section comprising one or more reactors operable to produce a syngas synthesis product stream comprising synthesis gas from the feed stream; a methanol synthesis section comprising one or more methanol synthesis reactors operable to produce a synthesis product comprising methanol; and/or a methanol purification section operable to remove at least one component from the synthesis product to provide a purified methanol product; wherein the methanol synthesis plant is configured such that, relative to a conventional methanol synthesis plant, more of the net energy required by the methanol synthesis plant, the feed pretreating section, the syngas generation section, the methanol synthesis section, the methanol purification section, or a combination thereof, is provided by a non-carbon based energy source, a renewable energy source, and/or electricity.Type: ApplicationFiled: January 14, 2020Publication date: April 21, 2022Applicant: SABIC Global Technologies B.V.Inventors: Joseph William SCHROER, Scott STEVENSON, Andrew Mark WARD, Tim ABBOTT, Kenneth Francis LAWSON, Michael Edward HUCKMAN, Zhun ZHAO, Arno OPRINS
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Patent number: 11208381Abstract: The present invention relates inter alia to a compound of formula (I) wherein R1, R2 and R3, are as defined in the specification and to compositions comprising the same and to the use of the compounds and to compositions of the compounds in treatment, for example in the treatment of fibrotic diseases or interstitial lung diseases, in particular idiopathic pulmonary fibrosis.Type: GrantFiled: June 1, 2020Date of Patent: December 28, 2021Assignee: RESPIVERT LIMITEDInventors: Iain Walters, Louise Birch, Stephen Paul Collingwood, Christopher Scott Stevenson
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Publication number: 20210269381Abstract: A process for producing methyl tert-butyl ether (MTBE) comprising introducing a butane feed stream (n-butane, i-butane) and hydrogen to a hydrogenolysis reactor comprising a hydrogenolysis catalyst to produce a hydrogenolysis product stream comprising hydrogen, methane, ethane, propane, i-butane, and optionally n-butane; separating the hydrogenolysis product stream into a first hydrogen-containing stream, an optional methane stream, a C2 to C3 gas stream (ethane, propane), and a butane stream (i-butane, optionally n-butane); feeding the butane stream to a dehydrogenation reactor to produce a dehydrogenation product stream, wherein the dehydrogenation reactor comprises a dehydrogenation catalyst, and wherein the dehydrogenation product stream comprises hydrogen, i-butane, and isobutylene; and feeding the dehydrogenation product stream and methanol to an etherification unit to produce an unreacted methanol stream, an unreacted isobutylene stream, and an MTBE stream.Type: ApplicationFiled: September 17, 2019Publication date: September 2, 2021Inventors: Dustin FICKEL, Scott STEVENSON, MyatNoeZin MYINT, Heng SHOU
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Patent number: 11090640Abstract: A method for preparing a hydrocracking catalyst comprising: (i) providing a shaped body comprising a zeolite and a binder, wherein the shaped body has been obtained by shaping, calcination and cooling, wherein the zeolite is ZSM-5 having a silica (SiO2) to alumina (Al2O3) molar ratio of 25-75; (ii) optionally drying the shaped body at a temperature of 100-300° C. for a period of at least 1 hour; (iii) depositing a hydrogenation metal on the shaped body by an impregnation for a period of at most 2 hours such that the amount of the hydrogenation metal is 0.010-0.30 wt % with respect to the total catalyst; (iv) optionally rinsing the metal deposited shaped body with water; and (v) heat-treating the metal deposited shaped body in air at a temperature of 250-300° C. for a period of 1-5 hours; wherein the catalyst comprises a total of less than 0.05 wt % sodium and cesium.Type: GrantFiled: October 17, 2017Date of Patent: August 17, 2021Assignee: SABIC GLOBAL TECHNOLOGIES B.V.Inventors: Ashim Kumar Ghosh, Alla Khanmamedova, Scott A. Stevenson
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Publication number: 20210233241Abstract: Risk prediction models are trained and deployed to analyze images, such as computed tomography scans, for predicting future risk of lung cancer for one or more subjects. Individual risk prediction models are separately trained on nodule-specific and non-nodule specific features such that each risk prediction model can predict future risk of lung cancer across different time periods (e.g., 1 year, 3 years, or 5 years). Such risk prediction models are useful for developing preventive therapies for lung cancer by enabling clinical trial enrichment.Type: ApplicationFiled: January 15, 2021Publication date: July 29, 2021Inventors: George R. Washko, JR., Christopher Scott Stevenson, Samuel Yoffe Ash, Raul San Jose Estepar, Matthew David Mailman
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Patent number: 11046672Abstract: The present invention relates inter alia to a compound of formula (I) Wherein R1, R2, R3 and Z are as defined in the specification and to compositions comprising the same and to the use of the compounds and to compositions of the compounds in treatment, for example in the treatment of fibrotic diseases or interstitial lung diseases, in particular idiopathic pulmonary fibrosis.Type: GrantFiled: December 23, 2016Date of Patent: June 29, 2021Assignee: RespiVert LimitedInventors: Iain Walters, Louise Birch, Joseph Hill-Cousins, Stephen Paul Collingwood, Christopher Scott Stevenson
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Publication number: 20210162380Abstract: Disclosed is a catalyst comprising a zeolite comprising a framework, the framework comprising silicon and aluminum, and a noble metal. The zeolite has undergone at least a first exchange with a Group I or II cation or ammonium and thereafter is contacted with a second Group I or II cation. The step of contacting comprises an exchange, incipient wetness, or dry impregnation. The noble metal is deposited at the zeolite.Type: ApplicationFiled: August 30, 2019Publication date: June 3, 2021Inventors: Travis CONANT, Dustin FARMER, Alla KHANMAMEDOVA, Neeta KULKARNI, Scott STEVENSON, Jun WANG
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Patent number: 11001772Abstract: A process for increasing olefin production from refinery that processes hydrocarbon streams that are rich in aromatic compounds and includes steam cracking and hydrotreating an aromatically rich feedstock to produce a hydrotreated pyrolysis gasoline stream and light pyrolysis oil byproduct, saturating at least one additional naphtha/hydrocarbon stream together with the hydrotreated pyrolysis gasoline stream or together with the light pyrolysis oil byproducts to form a first naphthene stream, and steam cracking the first naphthene stream to produce olefins.Type: GrantFiled: February 9, 2017Date of Patent: May 11, 2021Assignee: SABIC GLOBAL TECHNOLOGIES B.V.Inventors: Sheetal Bafna, Jose Armando Salazar-Guillen, Sanjeev Deshpande, Scott Stevenson, Michael Huckman, Joseph W. Schroer
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Publication number: 20210114982Abstract: The present invention relates inter alia to a compound of formula (I) wherein R1, R2 and R3, are as defined in the specification and to compositions comprising the same and to the use of the compounds and to compositions of the compounds in treatment, for example in the treatment of fibrotic diseases or interstitial lung diseases, in particular idiopathic pulmonary fibrosis.Type: ApplicationFiled: June 1, 2020Publication date: April 22, 2021Inventors: Iain Walters, Louise Birch, Stephen Paul Collingwood, Christopher Scott Stevenson
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Patent number: 10864505Abstract: The invention relates to a process for preparing a hydrocracking catalyst, comprising (i) contacting a shaped body comprising a zeolite and a binder with an aqueous solution of a hydrogenation metal compound which is a complex or a salt of a hydrogenation metal to deposit the hydrogenation metal onto the shaped body, wherein the aqueous solution comprises an ammonium salt and (ii) calcining the shaped body obtained by step (i).Type: GrantFiled: December 5, 2016Date of Patent: December 15, 2020Assignee: SABIC GLOBAL TECHNOLOGIES B.V.Inventors: Alla Khanmamedova, Ashim Kumar Ghosh, Scott Stevenson, David Sullivan, Pooja Bajaj