Abstract: A disconnector drill string has an uphole section and a downhole section coupled together by a disconnection sub, an operative length and an internal fluid conduit that extends along its operative length. The disconnection sub is operable to receive wirelessly a pre-designated command signal, to selectively couple the uphole section and the downhole section together, and to selectively uncouple the uphole section and the downhole section from one another. A method for using the disconnector drill string in a well bore includes the steps of introducing the disconnector drill string into the well bore, transmitting wirelessly the pre-designated command signal to the disconnection sub such that the disconnection sub selectively operates to uncouple the uphole section of the disconnector drill string from the downhole section of the disconnector drill string, and removing the uphole section of the disconnector drill string from the well bore.

Abstract: An aerator may be inserted into the neck of a wine bottle to aerate the wine as it is poured from the bottle. A cavity created in the distal end of the bottle as the wine is dispensed is vented to aid in high flow rate. The aerator seals against the inside surface of a typical wine bottle, and regulates pressures to create high flow and a high degree of aeration throughout the full dispense cycle of wine from the bottle.

Abstract: A device having a glasses mode, and methods therefor are provided. A display of the device is operated in a glasses mode by controlling the display to a first brightness level when the display is in the glasses mode. The display is operated to exit the glasses mode by controlling the display to a second brightness level when the display exits the glasses mode.

Abstract: A frame for a sign. The frame comprises a plurality of struts and corner brackets. The struts have an exposed front surface including a gripping means. Each corner bracket slidably engages with two of the struts at an angle. The corner brackets also have an exposed front surface including a gripping means. The gripping means of the struts is substantially continuous with the gripping means of the corner brackets so that when the corner brackets and struts are engaged to form a polygon, the polygon includes a substantially continuous gripping means that is engageable with a sign to mount the sign on the frame.

Abstract: Devices, systems, and methods for detection of an analyte in a sample are disclosed. In some embodiments, an optical sensor can include a metallic layer and a plurality of dielectric pillars extending through the metallic layer. A plurality of regions of concentrated light can be supported in proximity to the ends of the plurality of dielectric pillars when a surface of the metallic layer is illuminated. Concentrated light within one or more of these regions can interact with an analyte molecule, allowing for detection of the analyte.

Abstract: A railway inspection system for monitoring defects of a rail, including an inspection vehicle configured for traversing the rail, a sensor disposed on the vehicle configured for obtaining rail condition data, a memory disposed on the vehicle and storing previous rail condition data from a previous traversal of the rail, a display device disposed on the vehicle, a processor disposed on the vehicle and a non-transitory computer-readable medium disposed on the vehicle and containing instructions, which when executed by the processor, cause performance of the following steps in real-time as the vehicle traverses the rail, namely obtaining current rail condition data from the sensor, displaying on the display device representative images of the current rail condition data, retrieving the previous rail condition data from the memory, and displaying on the display device representative images of the previous rail condition data.

Abstract: A method is described by which a growth medium is exposed to an electric field of sufficient magnitude to kill competing microorganisms and insufficient magnitude to cause flocculation to an algae population.

Abstract: The present invention relates to altering the physical and/or chemical properties of at least part of at least one tissue in the eye. In a specific embodiment, it relates to the treatment of any eye disorder, although in particular embodiments the individual has a thickened Bruch's membrane. An activating energy source is utilized to effect a controlled diffusion enhancement and/or degradation of Bruch's membrane that enables improved diffusional transport between the choroid and retina. The individual is administered an inactivated diffusion-enhancing molecule that becomes associated with the membrane, which is then precisely exposed to an activating energy source, such as light or ultrasound.

Abstract: Described herein are systems, methods and apparatuses, for dewatering, flocculating and harvesting microorganisms. In various implementations, at least one intracellular product from the microorganisms is recovered and processed according to methods disclosed herein. In some implementations, an electromagnetic field is applied to an aqueous suspension of microorganisms thereby causing flocculation of the microorganisms. In various implementations, the microorganisms are harvested, such as by causing the microorganisms to flocculate and sink to the bottom of a container. Alternatively, the microorganisms are caused to flocculate and float to the surface of the aqueous medium where they can be recovered by skimming. In other implementations, the microorganisms are lysed as they are passed through a second electromagnetic field to release intracellular products, among other desired components of the microorganisms.

Abstract: In some aspects, a portable electronic device having a slidable upper housing and rear housing movable between an open position and a closed position, and a gain adjustment module. The gain adjustment module reduces the RF energy produced by the portable electronic device when the device is in the open position to ensure that the portable electronic device complies with Hearing Aid Compatibility (HAC) standards.

Abstract: A frame for a sign. The frame comprises a plurality of struts and corner brackets. The struts have an exposed front surface including a gripping means. Each comer bracket slidably engages with two of the struts at an angle. The corner brackets also have an exposed front surface including a gripping means. The gripping means of the struts is substantially continuous with the gripping means of the comer brackets so that when the comer brackets and struts are engaged to form a polygon, the polygon includes a substantially continuous gripping means that is engageable with a sign to mount the sign on the frame.

Abstract: The invention relates to compositions and methods useful in the acceleration of binding of target analytes to capture ligands on surfaces. Detection proceeds through the use of an electron transfer moiety (ETM) that is associated with the target analyte, either directly or indirectly, to allow electronic detection of the ETM.

Abstract: A method and system for a reverse online auction process include a dynamic rules-based configuration step. Question-and-answer sets having branches to other questions based on configured rules are generated. Vendor registrations are received from vendors, including vendor product and service information, vendor contact information, and vendor content. A vendor profile is created and stored for each vendor based the product and service information and on answers provided by the vendor to the question and answer sets. Client request leads received from clients are automatically matched to the vendor profile information to determine one or more selected vendors who receive the lead information. However, the received lead information excludes client contact information. Vendors may accept an opportunity to bid for the lead and thereby become candidate vendors. Candidate vendors may submit a bid for the lead, and at least one winning bidder is determined from the candidate vendors.

Abstract: The present invention relates to altering the physical and/or chemical properties of at least part of at least one tissue in the eye. In a specific embodiment, it relates to the treatment of any eye disorder, although in particular embodiments the individual has a thickened Bruch's membrane. An activating energy source is utilized to effect a controlled diffusion enhancement and/or degradation of Bruch's membrane that enables improved diffusional transport between the choroid and retina. The individual is administered an inactivated diffusion-enhancing molecule that becomes associated with the membrane, which is then precisely exposed to an activating energy source, such as light or ultrasound.

Abstract: The present invention relates to altering the physical and/or chemical properties of at least part of at least one tissue in the eye. In a specific embodiment, it relates to the treatment of any eye disorder, although in particular embodiments the individual has a thickened Bruch's membrane. An activating energy source is utilized to effect a controlled diffusion enhancement and/or degradation of Bruch's membrane that enables improved diffusional transport between the choroid and retina. The individual is administered an inactivated diffusion-enhancing molecule that becomes associated with the membrane, which is then precisely exposed to an activating energy source, such as light or ultrasound.

Abstract: The invention relates to novel magnetic resonance imaging contrast agents and methods of detecting physiological signals or substances.

Abstract: The methods described herein are methods to ascertain motion contrast within optical coherence tomography data based upon phase variance. The phase variance contrast observes the nanometer scale motion of scatterers associated with Brownian motion and other non-flow motion. The inventive method of calculating motion contrast from the phase variance can differentiate regions of different mobility based on the motion contrast differences, and can use the phase information to characterize mobility properties of the scatterers. In flow regions, the inventive method for acquiring and analyzing motion contrast can identify the regions as well as characterize the motion. Furthermore, the inventive method can determine quantitative flow estimation, the index of refraction variations, and absorption variations within flow regions.

Abstract: The present invention relates to the field of radio-frequency (RF) waveguides. More specifically, the present invention pertains to a method and apparatus that provides ultra-low-loss RF waveguide structures targeted between approximately 300 GHz and approximately 30 THz. The RF waveguide includes a hollow core and a flexible honeycomb, periodic-bandgap structure surrounding the hollow core. The flexible honeycomb, periodic-bandgap structure is formed of a plurality of tubes formed of a dielectric material such as of low-loss quartz, polyethylene, or high-resistivity silicon. Using the RF waveguide, a user may attach a terahertz signal source to the waveguide and pass signals through the waveguide, while a terahertz signal receiver receives the signals.

Abstract: Resonant sensors and methods of detecting specific molecules with enhanced sensitivity. Optical energy is introduced into a microcavity, such as a silica toroid-shaped microcavity. The microcavity sensor has a functionalized outer surface and a sufficiently high Q value to generate an evanescent optical field with increased intensity. A molecule bound to the functionalized outer surface interacts with the external optical field, thereby heating the microcavity and generating a detectable resonant wavelength shift, which indicates a small number of molecules, even a single molecule, without the use of fluorescent or metal labels. Resonant sensors and methods can also be used to detect specific molecules, even a single molecule, within an environment. One application is detecting very small quantities or a single molecule of heavy water in ordinary water.

Abstract: Gene trapping provides insertional mutagenesis strategies for monitoring the expression and localization of endogenous proteins. In accordance with the disclosure herein, a gene trapping vector and a method of fabrication and use are disclosed which provide for an efficient means of trapping and analyzing a gene of interest.