Abstract: A software image associated with a first customer of a computing resource service provider and criteria for identifying an event is received, the software image comprising a set of layers. The set of layers is stored in a first data store to form a stored set of layers, the first data store being physically located in a first region. The set of layers is copied to a second data store to form a copied set of layers, the second data store being physically located in a second region different from the first region. The copied set of layers is launched as a container executing in an instance that is physically located in the second region, and, as a result of identifying an occurrence of the event, the container is caused to be unavailable to an entity associated with the instance.

Abstract: A request to store, in first data store associated with a customer of a computing resource service provider, a software image is received, the request including a set of layers of the software image to be stored. As a result of successful authentication of the request, based at least in part on a security token included with the request, a subset of layers of the software image that have not previously been stored in the first data store are determined, based at least in part on first metadata obtained from a second data store, the subset of layers in the first data store are stored, second metadata about the subset of layers are stored in the second data store, and the software image is caused to be launched in a software container of an instance based at least in part on the subset of layers.

Abstract: In a cloud computing environment, a user authenticates to multiple cloud services concurrently. A master service has knowledge of or tracks the cloud service(s) to which a user is authenticated. Each cloud service may enforce its own inactivity period, and the inactivity period of at least first and second cloud services may be distinct from one another. When the master service receives an indication that the authenticated user is attempting to take an action at a first cloud service despite an activity timeout there, the master service issues a status request to at least the second cloud service to determine whether the user is still active at the second cloud service (despite its different inactivity period). If the user is still active at the second cloud service, the master service provides a response, selectively overriding (re-setting) the activity timeout at the first cloud service to permit the action.

Abstract: Semiconductor structures include an active region between a plurality of layers of InGaN. The active region may be at least substantially comprised by InGaN. The plurality of layers of InGaN include at least one well layer, and at least one barrier layer proximate the at least one well layer. Methods of forming semiconductor structures include growing such layers of InGaN to form an active region of a light emitting device, such as an LED. Luminary devices include such LEDs.

Abstract: The present invention provides a method for detecting mutations in the PALB2 gene in pancreatic cancer patients and in individuals having a family history of pancreatic cancer. Methods are also provided for diagnosing a predisposition to pancreatic cancer, for predicting a patient's response to pancreatic cancer therapies, and for treating pancreatic cancer, based on presence of a PALB2 mutation or abberant PALB2 gene expression in a patient.

Abstract: The present invention provides a method for detecting mutations in the PALB2 gene in pancreatic cancer patients and in individuals having a family history of pancreatic cancer. Methods are also provided for diagnosing a predisposition to pancreatic cancer, for predicting a patient's response to pancreatic cancer therapies, and for treating pancreatic cancer, based on presence of a PALB2 mutation or abberant PALB2 gene expression in a patient.

Abstract: Semiconductor structures include an active region between a plurality of layers of InGaN. The active region may be at least substantially comprised by InGaN. The plurality of layers of InGaN include at least one well layer, and at least one barrier layer proximate the at least one well layer. Methods of forming semiconductor structures include growing such layers of InGaN to form an active region of a light emitting device, such as an LED. Luminary devices include such LEDs.

Abstract: Semiconductor structures include an active region between a plurality of layers of InGaN. The active region may be at least substantially comprised by InGaN. The plurality of layers of InGaN include at least one well layer comprising InwGa1-wN, and at least one barrier layer comprising InbGa1-bN proximate the at least one well layer. In some embodiments, the value of w in the InwGa1-wN of the well layer may be greater than or equal to about 0.10 and less than or equal to about 0.40 in some embodiments, and the value of b in the InbGa1-bN of the at least one barrier layer may be greater than or equal to about 0.01 and less than or equal to about 0.10. Methods of fainting semiconductor structures include growing such layers of InGaN to form an active region of a light emitting device, such as an LED. Luminary devices include such LEDs.

Abstract: The present invention provides a method for detecting mutations in the PALB2 gene in pancreatic cancer patients and in individuals having a family history of pancreatic cancer. Methods are also provided for diagnosing a predisposition to pancreatic cancer, for predicting a patient's response to pancreatic cancer therapies, and for treating pancreatic cancer, based on presence of a PALB2 mutation or abberant PALB2 gene expression in a patient.

Abstract: In a cloud computing environment, a user authenticates to multiple cloud services concurrently. A master service has knowledge of or tracks the cloud service(s) to which a user is authenticated. Each cloud service may enforce its own inactivity period, and the inactivity period of at least first and second cloud services may be distinct from one another. When the master service receives an indication that the authenticated user is attempting to take an action at a first cloud service despite an activity timeout there, the master service issues a status request to at least the second cloud service to determine whether the user is still active at the second cloud service (despite its different inactivity period). If the user is still active at the second cloud service, the master service provides a response, selectively overriding (re-setting) the activity timeout at the first cloud service to permit the action.

Abstract: Efficient routing for a client-server session or connection is provided in an application layer of multi-layered systems interconnect stack by caching a plurality of application-specific information at an intermediary network point; using the application specific information to route messages for an application connection; and indexing the application-specific information with a key provided by the application. Optionally, a second key may be used to retrieve the application-specific information if the first key is not provided in an application connection request, where the second key is optionally opaque to the application program. The intermediary network point may be an edge of network Internet Protocol (IP) switch, and the application layer in which the routing is performed may be layer seven of the Open Systems Interconnection model.

Abstract: Semiconductor structures include an active region between a plurality of layers of InGaN. The active region may be at least substantially comprised by InGaN. The plurality of layers of InGaN include at least one well layer comprising InwGa1-wN, and at least one barrier layer comprising InbGa1-bN proximate the at least one well layer. In some embodiments, the value of w in the InwGa1-wN of the well layer may be greater than or equal to about 0.10 and less than or equal to about 0.40 in some embodiments, and the value of b in the InbGa1-bN of the at least one barrier layer may be greater than or equal to about 0.01 and less than or equal to about 0.10. Methods of fainting semiconductor structures include growing such layers of InGaN to form an active region of a light emitting device, such as an LED. Luminary devices include such LEDs.

Abstract: A secure database includes a catalog of information about one or more identity providers (IdPs) that are trusted by a service provider (SP) to authenticate users on the SP's behalf. The catalog securely stores one or more IdP configurations. An entry in the database stores information associated with the trusted IdP including artifacts to identify the IdP, artifacts used by the IdP for cryptographic operations, and a specification of one or more website(s) serviced by the trusted identity provider. Upon receipt by the SP of identity information representing a user that has authenticated to an IdP, information in the catalog of information is used to determine whether the IdP is trusted to authenticate the user on the service provider's behalf. The determination verifies that the SP uses the IdP and that a binding between an IdP identifier and at least one IdP cryptographic artifact is valid.

Abstract: The present invention relates to the field of cancer. More specifically, the present invention provides compositions and methods useful for treating cancer characterized by the expression of mutant FAM190A proteins. In a specific embodiment, a method for treating a patient having a cancer characterized by a FAM190A intragenic rearrangement comprises the step of administering to the patient an agent that inhibits a biological function or reduces the level or expression of the FAM190A protein.

Abstract: A rich client performs single sign-on (SSO) to access a web- or cloud-based application. According to the described SSO approach, the rich client delegates to its native application server the task of obtaining a credential, such as a SAML assertion. The native server, acting on behalf of the user, obtains an assertion from a federated identity provider (IdP) that is then returned to the rich client. The rich client provides the assertion to a cloud-based proxy, which presents the assertion to an identity manager to attempt to prove that the user is entitled to access the web- or cloud-based application using the rich client. If the assertion can be verified, it is exchanged with a signed token, such as a token designed to protect against cross-site request forgery (CSRF). The rich client then accesses the web- or cloud-based application making a REST call that includes the signed token. The application, which recognizes the request as trustworthy, responds to the call with the requested data.

Abstract: There are currently few therapeutic options for patients with pancreatic cancers and new insights into the pathogenesis of this lethal disease are urgently needed. To this end, we performed a comprehensive analysis of the genes altered in 24 pancreatic tumors. First, we determined the sequences of 23,781 transcripts, representing 20,583 protein-encoding genes, in DNA from these tumors. Second, we searched for homozygous deletions and amplifications using microarrays querying ˜one million single nucleotide polymorphisms in each sample. Third, we analyzed the transcriptomes of the same samples using SAGE and next-generation sequencing-by-synthesis technologies. We found that pancreatic cancers contain an average of 63 genetic alterations, of which 49 are point mutations, 8 are homozygous deletions, and 6 are amplifications. Further analyses revealed a core set of 12 regulatory processes or pathways that were each genetically altered in 70% to 100% of the samples.

Abstract: One or more data structures are received by a computing device, wherein the one or more data structures include at least one or more user credentials. The one or more user credentials are normalized by the computing device to generate a first graph. One or more nodes of the first graph and one or more nodes of at least a second graph are analyzed by the computing device, wherein analyzing includes at least identifying a logical correlation between the one or more nodes of the first graph and the one or more nodes of at least the second graph. A third graph is generated by the computing device based, at least in part, upon the analysis of the one or more nodes of the first graph and the one or more nodes of at least the second graph. An output data structure is generated by the computing device based, at least in part, upon the third graph.

Abstract: The present invention provides a method for detecting mutations in the PALB2 gene in pancreatic cancer patients and in individuals having a family history of pancreatic cancer. Methods are also provided for diagnosing a predisposition to pancreatic cancer, for predicting a patient's response to pancreatic cancer therapies, and for treating pancreatic cancer, based on presence of a PALB2 mutation or abberant PALB2 gene expression in a patient.

Abstract: One or more data structures are received by a computing device, wherein the one or more data structures include at least one or more user credentials. The one or more user credentials are normalized by the computing device to generate a first graph. One or more nodes of the first graph and one or more nodes of at least a second graph are analyzed by the computing device, wherein analyzing includes at least identifying a logical correlation between the one or more nodes of the first graph and the one or more nodes of at least the second graph. A third graph is generated by the computing device based, at least in part, upon the analysis of the one or more nodes of the first graph and the one or more nodes of at least the second graph. An output data structure is generated by the computing device based, at least in part, upon the third graph.

Abstract: A computer system for a rebate processing tool is provided. The computer system has a platform, at least one input device, and a central processing unit in communication with the platform and the at least one input device. The central processing unit is configured to receive, at a computer, a claim for one or more rebate programs and determine, by the computer, whether the claim satisfies one or more predetermined conditions. The central processing unit is also configured to approve the claim upon satisfaction of the predetermined conditions. The central processing unit is further configured to review the claim when at least one of the predetermined conditions is not satisfied.