Abstract: A circuit board assembly can include a circuit component die, a first dielectric layer disposed on a first side of the circuit component die made of a first dielectric material having a high thermal conductivity, a second dielectric layer disposed on a second side of the circuit component die made of the first dielectric material, and a bulk dielectric material having a lower thermal conductivity than the first dielectric material. The bulk dielectric material can have a lower glass transition temperature than the first dielectric material and being heterogeneous to the first dielectric material. The bulk dielectric material can be in flowed contact with lateral sides of the circuit component die, the first dielectric layer, and the second dielectric layer to laterally enclose the circuit component die, the first dielectric layer, and the second dielectric layer.

Abstract: The invention relates to methods of treating certain retinal vasculopathies such as diabetic macular edema, diabetic retinopathy and dry and neovascular age-related macular degeneration, among others. In some instances, the method includes treating a patient suffering from a retinal vasculopathy by administering an agent to the patient. The agent can be one or more of the agents as described herein.

Abstract: A method of determining a temperature of a patient includes measuring a first temperature of the patient with a temperature device, and measuring a second temperature of an environment with the temperature device. The method includes determining if a change in the ambient temperature exceeds a threshold. If the change does exceed the threshold, the method also includes applying a correction factor to the first temperature of the patient to account for the change in ambient temperature.

Abstract: In one embodiment, a method includes receiving, from a client system of a user, a user input comprising a plurality of n-grams, parsing the user input to identify one or more overall intents, hidden intents, and slots associated with the one or more n-grams, wherein at least one of the hidden intents is non-resolvable for being associated with partial slot information corresponding to an n-gram that has not been resolved to a particular entity identifier, wherein the partial slot information is associated with two more entity identifiers of two or more entities, respectively, sending, to the client system, instructions for prompting the user to select one of the entities to be associated with the non-resolvable hidden intent, resolving the non-resolvable hidden intent based on the entity identifier of the entity selected by the user, and generating a response to the user input based on the resolved hidden intent.

Abstract: A device for training users in a proper mixing of pharmaceutical components, or for aiding in the mixing, or for performing the mixing, and administration of pharmaceutical components is disclosed. The device comprises a housing for receiving a pharmaceutical delivery device containing the pharmaceutical components. There is also a microcontroller disposed in the housing and a motion/orientation detection device disposed within or on the housing and in communication with the microcontroller. A method for use of the device is also disclosed, along with a substance for use as one of the pharmaceutical components.

Abstract: An adapter includes a substantially rigid body having a distal portion, a proximal portion, a central opening formed at least in part by an inner wall of the body, and a longitudinal axis extending substantially centrally through the opening. The distal portion includes an annular ring having a top surface and a ridge disposed opposite the top surface, the ridge extending substantially perpendicular to the longitudinal axis. The distal. The adapter also includes a seal configured to form a substantially fluid-tight seal with a surface of a fitting removably attachable to the adapter.

Abstract: A panel system includes a chassis holding one or more tray arrangements, which are each configured to receive one or more cassettes at two or more bays. The tray arrangements and cassettes cooperate to define a cassette sensor arrangement and a port occupancy sensor arrangement having separate interface points. The cassette sensor arrangement may include electronic memory storing physical layer information about the cassette. All active components of the port occupancy sensor arrangement are disposed on the tray while the electronic memories of the cassette sensor arrangement are stored on the cassettes.

Abstract: A cooking oven wet bulb sensor system having: a reservoir configured to be secured to a cooking chamber wall of the cooking oven, with a cavity of the reservoir in an upward-facing orientation; a temperature sensor probe configured to be mounted at least partially within the cavity of the reservoir; and a water fill opening positioned to dispense water into the cavity. A cooking oven having a wet bulb sensor system and a method for operating a cooking oven are also provided.

Abstract: This application discloses anti-CCR7 antibodies, antigen binding fragments thereof, and antibody drug conjugates of said antibodies or antigen binding fragments. The invention also relates to methods of treating or preventing cancer using the antibodies, antigen binding fragments, and antibody drug conjugates. Also disclosed herein are methods of making the antibodies, antigen binding fragments, and antibody drug conjugates, and methods of using the antibodies and antigen binding fragments as diagnostic reagents.

Abstract: A male bayonet connector includes a first shaft having a first distal end portion having a first sealing surface configured to form a substantially fluid-tight seal with a female connector, a first proximal end portion opposite the first distal end portion, a first lumen extending substantially along a first longitudinal axis of the first shaft from the first distal end portion to the first proximal end portion, and a first channel formed on an outer surface of the first shaft between the first sealing surface and the first proximal end portion. The first channel at least partially extends circumferentially around the first longitudinal axis. The first channel is also defined by a first distal wall, a first proximal wall opposite the first distal wall, and a first central region extending from the first distal wall to the first proximal wall. The first distal wall includes a first axial length that is at least one of curved or at an acute angle relative to the first longitudinal axis.

Abstract: A dual reclaim coil with a smart control application is provided that allows the refrigerant inlet to the HVAC unit switch between the two sides of the condenser for heat reclaim for refrigerants such as CO2 which have a relatively low critical temperature compared to hydrofluorocarbon refrigerants. Heat reclaim after the exit of gas from the condenser utilizes the high temperature and pressure of the condenser/gas cooler outlet while a CO2 refrigerant system is operating above critical point. This occurs in hot ambient conditions, when the need for heating in the space is not as great as in the wintertime and the available heat at the condenser/gas cooler's outlet is sufficient to satisfy the heating load. When the CO2 refrigerant system is operating below the critical point, heat reclaim is carried out at the compressor discharge.

Abstract: Electrical connectors for very high speed signals, including signals at or above 112 Gbps. Effectiveness of shielding along the signal paths through the mating electrical connectors may be enhanced through the use of one or more techniques, including enabling two-sided shielding, connections between shield members and between shield members and grounded structures of printed circuit boards to which the connectors are mounted, and selective positioning of lossy material. Such techniques may be simply and reliably implemented in high density connector using one or more techniques. An electrical connector may include core members held by a housing together with leadframe assemblies attached to the core members. The core members may include features that would be difficult to mold in a housing and may include both shields and lossy materials in locations that would be difficult to incorporate in a leadframe assembly.

Abstract: An adapter includes a substantially rigid body having a distal portion, a proximal portion, a central opening formed at least in part by an inner wall of the body, and a longitudinal axis extending substantially centrally through the opening. The distal portion includes an annular ring having a top surface and a ridge disposed opposite the top surface, the ridge extending substantially perpendicular to the longitudinal axis. The distal. The adapter also includes a seal configured to form a substantially fluid-tight seal with a surface of a fitting removably attachable to the adapter.

Abstract: A refrigeration system includes a refrigeration subsystem and a coolant subsystem. The refrigeration subsystem is configured to circulate a refrigerant between an evaporator (12,22) within which a refrigerant absorbs heat and a gas cooler/condenser (2) within which the refrigerant rejects heat to provide cooling to a temperature-controlled space. The coolant subsystem includes a heat exchanger (61) coupled to the refrigeration subsystem at an outlet of the gas cooler/condenser and configured to transfer heat from the refrigerant exiting the gas cooler/condenser to an external coolant when the external coolant flows through the heat exchanger, a control valve (64), and a controller (50) configured to operate the control valve to control a flow of at least one of the refrigerant or the external coolant through the heat exchanger based on a temperature of the external coolant relative to a temperature of the refrigerant exiting the gas cooler/condenser.

Abstract: A family of connectors to accommodate a single twisted pair of conductors is disclosed herein. The family of connectors includes a free connector, a fixed connector, and an adapter; the free and/or fixed connectors can be modified to accommodate the adapter configuration and/or modified to accommodate various patch cord configurations. In certain embodiments, the one or more of the family of connectors adopts an LC fiber optic style connector configuration and an LC fiber optic footprint configuration. In certain examples, one or more of the family of connectors adopts an LC fiber optic style connector configuration but in a footprint that is larger or smaller than the footprint of the LC fiber optic footprint. Other configurations may also be adopted.

Abstract: A stairlift includes a rail and a carriage. The carriage includes a frame, a central drive unit mounted to the frame, the central drive unit including a drive motor and a drive gear, a yoke assembly pivotably mounted to the frame, and a first bogie unit attached to the yoke assembly and a second bogie unit attached to the yoke assembly, wherein each bogie unit includes a bogie socket mounted to the yoke assembly, and a bogie ball spherically pivotable within the bogie socket, the bogie ball including a plurality of bogie ball rollers configured to hold the bogie ball to the rail, and further wherein the plurality of bogie ball rollers are configured to maintain the bogie ball in a generally perpendicular travel orientation relative to the rail.

Abstract: A steam oven having a housing, a cooking chamber located within the housing, a water tank receptacle connected to the housing, the water tank receptacle comprising: a reservoir, an inlet fitting positioned above the reservoir, a false bottom positioned above the reservoir, and a reservoir outlet extending through a bottom of the reservoir. A water tank is selectively positionable on the water tank receptacle above the false bottom, the water tank having an outlet fitting configured to fluidily connect to the inlet fitting upon positioning the water tank on the water tank receptacle.

Abstract: A direct mate orthogonal connector for a high density of high speed signals. The connector may include right angle leadframe assemblies with signal conductive elements and ground shields held by a leadframe housing. High frequency performance may be achieved with members on the leadframe that transfer force between a connector housing, holding the leadframe assemblies, and a portion of the leadframe housing holding the signal conductive elements and the shields near their mounting ends. Core members may be inserted into the housing and mating ends of the conductive elements of ground shields may be adjacent the core members, enabling electrical and mechanical performance of the mating interface to be defined by the core members. The core members may incorporate insulative and lossy features that may be complex to form as part of the connector housing but may be readily formed as part of a separate core member.

Abstract: A male bayonet connector includes a first shaft having a first distal end portion having a first sealing surface configured to form a substantially fluid-tight seal with a female connector, a first proximal end portion opposite the first distal end portion, a first lumen extending substantially along a first longitudinal axis of the first shaft from the first distal end portion to the first proximal end portion, and a first channel formed on an outer surface of the first shaft between the first sealing surface and the first proximal end portion. The first channel at least partially extends circumferentially around the first longitudinal axis. The first channel is also defined by a first distal wall, a first proximal wall opposite the first distal wall, and a first central region extending from the first distal wall to the first proximal wall. The first distal wall includes a first axial length that is at least one of curved or at an acute angle relative to the first longitudinal axis.