Abstract: A system for reducing proarrhythmic effects of neural stimulation is provided. One aspect of this disclosure relates to an implantable medical device (IMD) for reducing proarrhythmic effects of neural stimulation. The IMD includes a neural stimulator adapted to deliver an electrical signal through at least one electrode to provide vagal stimulation. The IMD also includes a controller adapted to receive atrial arrhythmia vulnerability data and to control a therapeutic stimulator to limit atrial proarrhythmia using the atrial arrhythmia vulnerability data. The controller is further adapted to receive atrial arrhythmic history data and to control a therapeutic stimulator to limit atrial proarrhythmia using the atrial arrhythmic history data, according to various embodiments. According to one embodiment, the therapeutic stimulator includes the neural stimulator. The therapeutic stimulator includes a cardiac stimulator adapted to provide cardiac rhythm management therapy, according to various embodiments.

Abstract: Systems and methods to improve the visualization of vasculature in OCT angiography data are presented. In one embodiment, vessels having a particular orientation relative to one or more reference surfaces are highlighted. In another embodiment, the path of individual vessels can be analyzed to determine how many or what layers the vessels traverse. In another embodiment, regions which are typically not vascularized are analyzed for the presence of vessels. Techniques to minimize the impact of shadow artifacts are also presented and can be applied to any of the visualization approaches for further enhancement.

Abstract: A method for calculating the power of an intraocular lens including measuring an axial separation between the front surface of the cornea and the plane of the iris root; and determining the power of the intraocular lens using the measured axial separation together with other measured parameters and empirically determined lens constants.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example medical device may include a catheter shaft with a plurality of electrodes coupled thereto and a processor coupled to the catheter shaft. The processor may be capable of collecting a set of signals from the plurality of electrodes and generating a data set from at least one of the set of signals. The data set may include at least one known data point and one or more unknown data points. The processor may also be capable of interpolating at least one of the unknown data points by conditioning the data set, assigning an interpolated value to at least one of the unknown data points, and assigning a confidence level to the interpolated value.

Abstract: Analysis of an Internet content publisher's web pages to identify third-party vendor tags, as well as piggyback vendor tags called during execution of a given web page, that ultimately cause various types of secondary (“foreign”) content (e.g., ads, trackers, analytics, widgets, privacy assets) to be present in the content publisher's web pages when rendered by a browser on a client computing device. Such analysis also reveals the sources of the tags and the foreign content, and parent-child relationships (“parentage”) amongst vendor tags. A graphical representation is then rendered that includes one or more visualizations of the identified vendor tags, and the corresponding sources of the tags and the foreign content in the content publisher's web pages, as well as other information relating to the tags, the foreign content and their sources (e.g., parentage, classification of content, timing of called tags, latency resulting from tags, secure/unsecure calls to foreign resources, etc.).

Abstract: An optical coherence tomography device is disclosed for improved imaging. Reduced levels of speckle in the images generated by the device are obtained by forming a B-scan from a plurality of A-scans, wherein each resolution cell of the B-scan is generated through compounding of a subset of the A-scans and wherein at least some of the subset of A-scans are separated by at least half the diameter of a speckle cell both tangent to and orthogonal to the B-scan at that cell.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example method may include a method of identifying an activation time in a cardiac electrical signal. The method may include sensing a cardiac electrical signal, generating an approximation signal based at least in part on one or more parameters of the cardiac electrical signal, identifying a fiducial point on the approximation signal and determining, based at least in part on a timing of the fiducial point in the approximation signal, an activation time in the cardiac electrical signal.

Abstract: A catheter system includes a mapping catheter including a plurality of mapping electrodes, each mapping electrode configured to sense signals associated with an anatomical structure. The catheter system further includes a processor operatively coupled to the plurality of mapping electrodes and configured to receive the signals sensed by the plurality of mapping electrodes, characterize the signals sensed by the plurality of mapping electrodes based on a signal parameter of the sensed signals, and generate an output of a quality of contact of the plurality of mapping electrodes with the anatomical structure based on the signal characterization.

Abstract: For the pre-operative calculation of the power of an intraocular lens, three input parameters are needed: the axial length of the eye (AL), the refractive power of the cornea, and the distance between the front of the cornea and the back focal plane of the intraocular lens, the so-called effective lens position (ELP). The invention shows a novel approach to the determination of the ELP.

Abstract: Devices, in vitro cell cultures, systems, and methods are provided for microscale cell culture analogous (CCA) device.

Abstract: A catheter system includes a mapping catheter including a plurality of mapping electrodes, each mapping electrode configured to sense signals associated with an anatomical structure. The catheter system further includes a processor operatively coupled to the plurality of mapping electrodes and configured to receive the signals sensed by the plurality of mapping electrodes, characterize the signals sensed by the plurality of mapping electrodes based on amplitudes of the sensed signals, and generate an output of a quality of contact of the plurality of mapping electrodes with the anatomical structure based on the signal characterization.

Abstract: A system for delivering oxygen to a patient through an airway includes an airway connector and a nasal cannula holder. The airway connector includes a first connector portion configured to be inserted into the airway, a second connector portion having an open end opposite the first connector portion, and a sample port disposed in a side of the second connector portion. The nasal cannula holder includes a first holder portion configured to connect to the second portion of the airway connector, a second holder portion connected to the first holder portion, and a nasal cannula port disposed in a side portion of the second holder portion configured to receive the nasal prongs of a nasal cannula to deliver oxygen to the patient.

Abstract: Medical devices and methods for making and using medical devices are disclosed. An example method may include a method of identifying an activation time in a cardiac electrical signal. The method may include sensing a cardiac electrical signal, generating an approximation signal based at least in part on one or more parameters of the cardiac electrical signal, identifying a fiducial point on the approximation signal and determining, based at least in part on a timing of the fiducial point in the approximation signal, an activation time in the cardiac electrical signal.

Abstract: A packaging wrap for hangers includes a first side and a second side. The first side includes a first bottom panel, a first front panel, a first top panel, and a first rear panel. The first side is folded to define a first closed loop with an opening extending therethrough between the first bottom panel, the first front panel, the first top panel, and the first rear panel. The second side includes a second bottom panel, a second front panel, a second top panel, and a second rear panel. The second side is folded to define a second closed loop with an opening extending therethrough between the second bottom panel, the second front panel, the second top panel, and the first rear panel. The first side is coupled to the second side via a fold line extending along a boundary between the first bottom panel and the second bottom panel.

Abstract: An undercarriage light assembly includes a light element, a translucent jacket exterior to and surrounding the light element, and an outer housing positioned exterior to and surrounding at least a portion of the translucent jacket. The outer housing includes a first side, a second side connected to the first side, and a third side connected to the second side. The first and third sides are angled toward one another. An opening between the first and third sides allows for light to pass from the light element through the outer housing.

Abstract: Methods and devices for classifying a cardiac pacing response involve using a first electrode combination for pacing and a second electrode combination for sensing a cardiac signal following pacing. The cardiac response to pacing may be classified using the sensed cardiac signal. One process involves using the sensed cardiac signal to detect the cardiac response as a fusion/pseudofusion beat. Another process involves using the sensed cardiac signal to classify the cardiac response to pacing as one of at least three cardiac response types.

Abstract: The present disclosure relates, according to some embodiments, to systems and methods for processing organic compounds, such as manure or other organic waste. Embodiments may comprise a first containment chamber, a first anaerobic chamber, and a second anaerobic chamber. A first anaerobic chamber may receive organic compounds from a first containment chamber, and may provide a fluid stream to a second anaerobic chamber. The second anaerobic chamber may comprise a substrate, such as lava rock, with bacteria growing thereon. Further, a sulfide gas treating unit may receive and treat sulfide gases from a first anaerobic chamber and/or a second anaerobic chamber. A water storage unit may receive and store waste water or effluent from a first anaerobic chamber and/or a second anaerobic chamber.

Abstract: A method and apparatus is described for preventing or reducing the ventricular remodeling that normally occurs after a myocardial infarction using pacing therapy. By pacing sites in proximity to the infarct with appropriately timed pacing pulses, the infarct region is pre-excited in a manner that lessens the mechanical stress to which it is subjected, thus reducing the stimulus for remodeling. If capture by the pacing pulses is not being achieved, the device may be configured to change the pacing pulse energy and/or pacing site as appropriate.

Abstract: A cell culture method using an in vitro microscale cell culture device having a first microscale chamber containing cells attached to an inner surface of the chamber and cell culture medium in contact with the cells. The cells are maintained in culture in the in vitro microscale cell culture device while flowing culture medium through the first chamber at a controlled rate to provide a liquid residence time value for the cells in the first chamber of the in vitro microscale cell culture device that is comparable to a liquid residence time value obtained with respect to comparable cells in vivo, such that metabolism by the cells in culture in the in vitro microscale cell culture device is comparable to metabolism by comparable cells in vivo.