Abstract: A quick-connect fitting that provides a leak-proof connection between two components of a waterway. The quick-connect fitting of the present disclosure is releasable and reusable for disconnecting and reconnecting the waterway connection. Moreover, the quick-connect fitting further comprises an audible identifier which identifies the quick-connect fitting has secured the waterway components to be connected.

Abstract: A compound of formula (I): wherein: R1 is selected from (i) H, (ii) C3-6cycloalkyl, (iii) C3-7heterocyclyl optionally substituted with a group selected from: methyl and ester, and (iv) linear or branched C1-4alkyl optionally substituted with a group selected from: alkoxy, amino, amido, acylamido, acyloxy, alkyl carboxyl ester, alkyl carbamoyl, alkyl carbamoyl ester, phenyl, phosphonate ester, C3-7heterocyclyl optionally substituted with a group selected from methyl and oxo, and a naturally occurring amino acid, optionally N-substituted with a group selected from methyl, acetyl and boc; A1 is CRA or N; A2 is CRB or N; A3 is CRC or N; A4 is CRD or N; where no more than two of A1, A2, A3, and A4 may be N; one or two of RA, RB, RC, and RD, (if present) are selected from H, F, Cl, Br, Me, CF3, cyclopropyl, cyano, OMe, OEt, CH2OH, CH2OMe and CH2NMe2; the remainder of RA, RB, RC, and RD, (if present) are H; Y is O, NH or CH2; RY is selected from: (RYA) and (RYB).

Abstract: A fluid coupling for use with a reservoir of a water distribution system, such as a ganged reservoir system.

Abstract: According to various embodiments, systems, devices and methods for modulating targeted nerve fibers (e.g., hepatic neuromodulation) or other tissue are provided. The systems may be configured to access tortuous anatomy of or adjacent hepatic vasculature. The systems may be configured to target nerves surrounding (e.g., within adventitia of or within perivascular space of) an artery or other blood vessel, such as the common hepatic artery.

Abstract: A pipe nipple insert and dip tube for use with a water heater having a pipe nipple, the dip tube including a pipe nipple insert and a tubular body. The pipe nipple insert includes an outer wall and a plurality of annular crush rings extending radially from the outer wall. An overlapping connection is included at a bottom of the pipe nipple insert and a top of the tubular body for connecting the bottom of the pipe nipple insert to the top of the tubular body, wherein either the bottom of the pipe nipple insert overlaps the top of the tubular body or the top of the tubular body overlaps the bottom of the pipe nipple insert.

Abstract: A compound of formula (I), or a pharmaceutically acceptable salt thereof:

Abstract: According to various embodiments, systems, devices and methods for modulating targeted nerve fibers (e.g., hepatic neuromodulation) or other tissue are provided. The systems may be configured to access tortuous anatomy of or adjacent hepatic vasculature. The systems may be configured to target nerves surrounding (e.g., within adventitia of or within perivascular space of) an artery or other blood vessel, such as the common hepatic artery.

Abstract: A quick-connect fitting that provides a leak-proof connection between two components of a waterway. The quick-connect fitting of the present disclosure is releasable and reusable for disconnecting and reconnecting the waterway connection. Moreover, the quick-connect fitting further comprises an audible identifier which identifies the quick-connect fitting has secured the waterway components to be connected.

Abstract: An imaging system, optionally an intra-oral camera, includes a blue light source and a barrier filter over a camera sensor. Optionally, the imaging system can also take white light images. Optionally, the system includes positively charged nanoparticles with fluorescein. The fluorescent nanoparticles can be identified on an image of a tooth by machine vision or machine learning algorithms on a pixel level basis. Either white light or fluorescent images can be used, with machine learning or artificial intelligence algorithms, to score the lesions. However, the white light image is not useful for determining whether lesions, particularly ICDAS 0-2 lesions, are active or inactive. A fluorescent image, with the fluorescent nanoparticles, can be used to detect and score active lesions. Optionally using a white light image and a fluorescent image together allows for all lesions, active and inactive, to be located and scored, and for their activity to be determined.

Abstract: A compound of formula (I), or a pharmaceutically acceptable salt thereof.

Abstract: The disclosure herein relates to a quick-connect fitting that provides a leak-proof connection between two components of a waterway. The quick-connect fitting of the present disclosure is releasable and reusable for disconnecting and reconnecting the waterway connection. Moreover, the quick-connect fitting further comprises an audible identifier which identifies the quick-connect fitting has secured the waterway components to be connected.

Abstract: A system for air compression, storage and expansion may include a low-pressure and a high-pressure compressor, a motor, a heat storage, an air storage volume, a high-pressure and a low-pressure turbine, and a generator. The system may further include a first air path connecting sequentially the low-pressure compressor, the heat storage, the high-pressure compressor, and the air storage volume. The system may further include a second air path connecting sequentially the air storage volume, the high-pressure turbine, the heat storage, and the low-pressure turbine.

Abstract: A compound of formula (I): wherein: R1 is selected from (i) H, (ii) C3-6cycloalkyl, (iii) C3-7heterocyclyl optionally substituted with a group selected from: methyl and ester, and (iv) linear or branched C1-4alkyl optionally substituted with a group selected from: alkoxy, amino, amido, acylamido, acyloxy, alkyl carboxyl ester, alkyl carbamoyl, alkyl carbamoyl ester, phenyl, phosphonate ester, C3-7heterocyclyl optionally substituted with a group selected from methyl and oxo, and a naturally occurring amino acid, optionally N-substituted with a group selected from methyl, acetyl and boc; A1 is CRA or N; A2 is CRB or N; A3 is CRC or N; A4 is CRD or N; where no more than two of A1, A2, A3, and A4 may be N; one or two of RA, RB, RC, and RD, (if present) are selected from H, F, Cl, Br, Me, CF3, cyclopropyl, cyano, OMe, OEt, CH2OH, CH2OMe and CH2NMe2; the remainder of RA, RB, RC, and RD, (if present) are H; Y is O, NH or CH2; RY is selected from: (RYA) and (RYB).

Abstract: The disclosure described herein relates to a beverage dispensing system mixing nozzle and a process for making or repairing the same. Particular examples of the present disclosure include a manifold comprising multiple tubes where the manifold is inserted into and secured within a seat of the mixing nozzle. In some examples, multiple manifolds are inserted into and secured within a seat of the mixing nozzle. The tubes extend into the body of the manifold to form a leak proof connection.

Abstract: A compound of formula (I), wherein R1 is selected from (i) H, (ii) C3-6cycloalkyl, (iii) C3-7heterocyclyl optionally substituted with a group selected from: methyl and ester, and (iv) linear or branched C1-4alkyl optionally substituted with a group selected from: alkoxy, amino, amido, acylamido, acyloxy, alkyl carboxyl ester, alkyl carbamoyl, alkyl carbamoyl ester, phenyl, phosphonate ester, C3-7heterocyclyl optionally substituted with a group selected from methyl and oxo, and a naturally occurring amino acid, optionally N-substituted with a group selected from methyl, acetyl and boc; A1 is CRA or N; A2 is CRB or N; A3 is CRC or N; A4 is CRD or N; where no more than two of A1, A2, A3, and A4 may be N; one or two of RA, RB, RC, and RD, (if present) are selected from H, F, Cl, Br, Me, CF3, cyclopropyl, cyano, OMe, OEt, CH2OH, CH2OMe and CH2NMe2; the remainder of RA, RB, RC, and RD, (if present) are H; Y is O, NH or CH2; RY is selected from: (RYA) and (RYB).

Abstract: This invention relates in general to a multilayer tube and methods of making the same. In particular, this invention relates to a multilayer tube used as a riser, such as those that may be connected to shutoff or “stop” valve on one end and a plumbing hook-up to the other end. The multilayer tube comprises a first inner polymer layer and a second outer polymer layer, wherein the first and second polymer layers are not substantially bonded to each other. To facilitate use, the tube may additionally comprise one or more overmolded components, such as pipe connectors, plumbing connections, plumbing fittings, valve connectors and appliance connectors. The layers are not substantially bonded.

Abstract: A cell culture bioreactor has membranes divided into a plurality of zones. The membranes may include perfusion membranes carrying a liquid media and/or gas transfer membranes. The bioreactor has one or more sensors configured to collect data from one or more locations within the bioreactor. The supply of one or more of the gaseous and/or liquid media to a selected zone or zones may be controlled. In some examples, the supply includes a background supply and a selectable incremental supply. The bioreactor may be used to grow cells in suspension. Liquid media circulates within an extra-capillary space of the bioreactor. In some examples, a portion of cells is permitted for a period of time to be restrained within one or more zones of the membranes. Elements of a reactor may be made in a mold. A reactor may be operated in a fed-batch process.

Abstract: A CO2 separation and liquefaction system such as might be used in a carbon capture and sequestration system for a fossil fuel burning power plant is disclosed. The CO2 separation and liquefaction system includes a first cooling stage to cool flue gas with liquid CO2, a compression stage coupled to the first cooling stage to compress the cooled flue gas, a second cooling stage coupled to the compression stage and the first cooling stage to cool the compressed flue gas with a CO2 melt and provide the liquid CO2 to the first cooling stage, and an expansion stage coupled to the second cooling stage to extract solid CO2 from the flue gas that melts in the second cooling stage to provide the liquid CO2.

Abstract: Systems and methods for point-to-point encryption compliance are disclosed. In one embodiment, in an information processing apparatus comprising at least one computer processor, a method for point-to-point encryption compliance may include: (1) a payment application receiving, from a data source, payment data encrypted using a first encryption method; (2) the payment application identifying a second encryption method for the payment data; (3) the payment application requesting, from the data source, the payment data encrypted using the second encryption method; and (4) the payment application receiving from the data source, the payment data encrypted using the second encryption method.

Abstract: Image data is used to determine wind speed and wind direction during takeoff and landing by an unmanned aerial vehicle (UAV). The flight data, including image data, may be received using sensors onboard the UAV and/or the flight data may be received from other sources, such as nearby anemometer, cameras, other UAVs, other vehicles, and/or local weather stations. Machine learning models may train using the flight data gathered by the UAVs to determine the wind velocity based on image data. The UAV may adjust flight control settings to generate side forces to overcome the predicted wind velocity.