Abstract: A novel maleate salt of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) is provided.

Abstract: A novel L-malate salt of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) is provided.

Abstract: A novel maleate salt of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) is provided.

Abstract: A novel L-malate salt of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) is provided.

Abstract: A novel besylate salt of (6-(5-chloro-2-pyridyl)-5-[(4-methyl-1-piperazinyl)carbonyloxy]-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazine) is provided.

Abstract: This invention provides a convenient method for converting oximes into enamides. The process does not require the use of metallic reagents. Accordingly, it produces the desired compounds without the concomitant production of a large volume of metallic waste. The enamides are useful precursors to amides and amines. The invention provides a process to convert a prochiral enamide into the corresponding chiral amide. In an exemplary process, a chiral amino center is introduced during hydrogenation through the use of a chiral hydrogenation catalyst. In selected embodiments, the invention provides methods of preparing amides and amines that include the 1,2,3,4-tetrahydro-N-alkyl-1-naphthalenamine or 1,2,3,4-tetrahydro-1-naphthalenamine substructure.

Abstract: The compound of formula (I) is a water-stable, long acting ?2-selective adrenoceptor agonist useful as a bronchodilator in the treatment of bronchoconstriction associated with reversible obstructive airways diseases and the like.

Abstract: The compound of formula (I) is a water-stable, long acting ?2-selective adrenoceptor agonist useful as a bronchodilator in the treatment of bronchoconstriction associated with reversible obstructive airways diseases and the like.

Abstract: Modular drop-glass window assemblies include a vertically slidable pane, at least one stationary pane having an inboard vertical edge proximate to the exterior surface of the slidable pane and framing holding the stationary pane(s) and at least partially defining a window opening that is opened and closed by movement of the slidable pane. The framing includes vertical frame portions defining run channels for guiding the slidable pane between its open and closed positions. No portion of the vertical frame portions extends exteriorly beyond the plane of the exterior surface of a stationary pane.

Abstract: One aspect of the present invention relates to pharmaceutical compositions containing two or more active agents that when taken together can be used to treat, e.g., menopause, mood disorders, anxiety disorders, or cognitive disorders. The first component of the pharmaceutical composition is a sedative eszopiclone. The second component of the pharmaceutical composition is trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-napthalenamine or trans 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-1-napthalenamine. The present invention also relates to a method of treating menopause, perimenopause, mood disorders, anxiety disorders, and cognitive disorders.

Abstract: This invention encompasses novel methods of preparing sulfinamides and sulfoxides, particularly stereomerically pure sulfinamides and sulfoxides. The invention further encompasses novel compounds from which sulfinamides and sulfoxides can be prepared.

Abstract: A rotor for a wind turbine generator includes a rotatable hub forming a cavity. A plurality of rotor blades is connected to the hub. A heat sink is at least partially positioned within the cavity and extends along a portion of a corresponding rotor blade. The heat sink includes a bottom surface mounted on a thermal energy generating component of the wind turbine generator. An opposing top planar surface includes a plurality of pins extending therefrom. The pins form an air flow path through the pins to dissipate the generated thermal energy from the thermal energy generating component.

Abstract: A method for powering a pitch motor drive system for at least one DC pitch motor of a wind turbine includes rectifying a voltage using a bridge circuit to thereby supply a DC link voltage to a bridge comprising active switching devices, and utilizing at least one link capacitor to smooth the DC link voltage and act as an energy sink and source for the DC pitch motor or motors.

Abstract: The present invention foregoes use of PVC in printable media and instead provides a lightweight recyclable display media comprised generally of a printable coated scrim. The display media includes a base layer or scrim comprised of a polymer material and formed by woven, non-woven, or knit sheet-forming techniques. A non-vinyl body coating is applied to the base layer to add stiffness, body, and printability to the media. The body layer is comprised, at least partially, of urethane, acrylic, or blended urethane/acrylic materials. These materials add body and durability to the base layer without presenting the environmental difficulties attributable to PVC. The non-vinyl body coating may further comprise ink receptive materials or fillers that enhance ink retention in the media. The display media may be printed through a variety of printing techniques known in the art.

Abstract: An articulating window assembly is adapted for use with a vehicle. The assembly includes a windowpane with an inner surface and a hinge adjacent to the inner surface. The hinge includes a stationary member having a pivot element with cylindrical extensions and a central portion of larger cross-sectional area than the cylindrical extensions. The hinge further includes a mounting element extending at an angle from the pivot element. A polymeric member surrounds at least a portion of the cylindrical extensions so as to permit the hinge member to articulate about the pivot axis. Optionally, the polymeric member defines a cavity adjacent the central portion on the compression side of the stationary member to provide clearance of the polymeric member when the window is opened.

Abstract: This invention encompasses novel methods of preparing sulfinamides and sulfoxides, particularly stereomerically pure sulfinamides and sulfoxides. The invention further encompasses novel compounds from which sulfinamides and sulfoxides can be prepared.

Abstract: Apparatus and method for providing DMA transfers between an adapter card with or with out DMA capabilities and a system CPU with DMA capabilities. An adapter DMA controller circuit resides between the system CPU and the adapter card. This adapter DMA controller allows the system to run in immediate mode which allows the system CPU to talk to the adapter card as if the adapter DMA controller was not there. The system can also run in DMA mode. In this mode the system CPU sets up the system DMA controller and the adapter DMA controller. The adapter DMA controller takes over sending or receiving data to the adapter card and then requesting a DMA transfer with the system DMA controller. The transfer of data between the adapter DMA controller and the adapter does not use any system CPU resources such as the data and address busses. The system CPU is free to use the system resources to continue operation.

Abstract: This invention encompasses novel methods of preparing sulfinamides and sulfoxides, particularly stereomerically pure sulfinamides and sulfoxides. The invention further encompasses novel compounds from which sulfinamides and sulfoxides can be prepared.

Abstract: A sensor detects skewed adjacent movable components. The sensor may be used to detect harmful skews of aircraft control surfaces, such as slats or flaps on aircraft wings, which may be caused by an actuator disconnection from the surface it drives. Harmful skew, which is a relative asymmetrical motion of control surfaces beyond a predetermined limit, is detected by the sensor, but the relatively smaller harmless skew caused by normal flight is ignored. The sensor comprises first and second arms connected to a common base that may be attached to a first control surface. A constraining means such as a mechanical fuse holds the arms together while a separating means such as a spring exerts a separating force on the arms when the fuse breaks. A switching means is integral to the two arms. A striker pin on a second control surface strikes the first or second sensor arm when the relative motion between the control surfaces exceeds a certain predetermined limit.

Abstract: A sensor detects skewed adjacent movable component. The sensor may be used to detect harmful skews of aircraft control surfaces, such as slats or flaps on aircraft wings, which may be caused by an actuator disconnection from the surface it drives. Harmful skew, which is a relative asymmetrical motion of control surfaces beyond a predetermined limit, is detected by the sensor, but the relatively smaller harmless skew caused by normal flight is ignored. The sensor comprises first and second arms connected to a common base that may be attached to a first control surface. A constraining means such as a mechanical fuse holds the arms together while a separating means such as a spring exerts a separating force on the arms when the fuse breaks. A switching means is integral to the two arms. A striker pin on a second control surface strikes the first or second sensor arm when the relative motion between the control surfaces exceeds a certain predetermined limit.