Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: Abstract of the Disclosure The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: Abstract of the Disclosure The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: Abstract of the Disclosure The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: Abstract of the Disclosure The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: Abstract of the Disclosure The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: Abstract of the Disclosure The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: Abstract of the Disclosure The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: Abstract of the Disclosure The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: Abstract of the Disclosure The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: Abstract of the Disclosure The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: Abstract of the Disclosure Systems and methods for manufacture of an analyte-measuring device, including adhering a membrane system that allows the passage of the analyte therethrough to a sensing mechanism. The implantable analyte-measuring device includes a body formed from a material that is substantially similar to the membrane system so as to enable sufficiently strong adhesion therebetween, which enables a sufficiently strong adhesive joint capable of withstanding in vivo cellular forces. In some embodiments, the device body includes an insert to which the membrane system is adhered, wherein the insert is formed from a material substantially similar to the membrane system to enable strong adhesion therebetween. The analyte-measuring device is designed with optimized device sizing and maximum membrane adhesion and longevity to enable controlled transport of analytes through the membrane system in vivo with improved device performance.

Abstract: The present invention provides a defect patch device and method that patches a defect in the heart or other cardiovascular tissue. One aspect provides a PFO closure device and method that patches a PFO in the right atrium without the device extending through the PFO into the left atrium. The patch device includes a patch and a heart tissue engaging member for attaching the device over the defect. A deployment device and method includes a device positioner to advance the device out of a catheter and to position the device over the defect to attach the device to the tissue around the defect. The positioner may include a device expander or opener that opens the device for deployment.

Abstract: Abstract of the Disclosure Systems and methods for integrating a continuous glucose sensor, including a receiver, a medicament delivery device, and optionally a single point glucose monitor are provided. Manual integrations provide for a physical association between the devices wherein a user (for example, patient or doctor) manually selects the amount, type, and/or time of delivery. Semi-automated integration of the devices includes integrations wherein an operable connection between the integrated components aids the user (for example, patient or doctor) in selecting, inputting, calculating, or validating the amount, type, or time of medicament delivery of glucose values, for example, by transmitting data to another component and thereby reducing the amount of user input required. Automated integration between the devices includes integrations wherein an operable connection between the integrated components provides for full control of the system without required user interaction.

Abstract: Systems and methods for implantable devices that transmit and receive RF transmissions are provided. More particularly, the implantable device includes an antenna encapsulated within a non-hermetic material, wherein the antenna is spaced from the non-hermetic material by an air gap. Preferably, the spacing is provided by one or more enclosures that maintain the air gap surrounding the antenna during and after the manufacture of the device. The one or more enclosures can be in the form or tubing formed from glass, or the like, at least partially surrounding the antenna. By increasing the amount of air encapsulated within the implantable device, and particularly proximal to (e.g., around) the antenna, the susceptibility to changes in RF performance is reduced.

Abstract: Devices suitable for implantation in a body of a host and systems and methods for their manufacture are provided. The implantable devices include a composite material formed at least from a matrix material and hollow gas-filled beads. In preferred embodiments, the composite material includes a polymeric matrix mixed with hollow air-filled glass beads, which are mixed and cured to form at least a portion of the body of the implantable device. Implantable devices including this composite material have decreased weight and/or overall density as compared to implantable devices without the beads incorporated therein, which is believed to improve the acceptance and function of the implantable device in vivo. Additionally, implantable devices concerned with transmitting and receiving via RF are believed to achieve improved RF performance due to a reduced dielectric constant provided by the incorporation of beads within the composite material.

Abstract: A system, device and method for repairing mitral valve regurgitation is provided. A device is placed external to the mitral valve in the atrioventricular sulcus or groove of the heart and is cinched in to reduce the mitral valve annulus or the radius of curvature of the heart around the atrioventricular groove thus reducing the circumference of the mitral annulus.