Abstract: A separating and/or insulation removal device for a cable-processing machine has at least two knife blocks that can be moved in opposite directions, each with at least one knife. A cable that is to be cut to length and/or is to have its insulation removed can be guided between the knives, which are actuated by at least one drive for at least one of the knife blocks, and a mechanism for purposes of guiding at least the driven knife block in the direction towards the cable. The drive acts at least indirectly on an element of the mechanism. Each driven knife block sits on a lever at a distance from its lever axis and executes a pivotal movement along a circular arc. For this purpose, the drive engages with the lever via a rotatable force transmission element at a distance from the lever axis and the knife block.

Abstract: The present disclosure relates to an apparatus for the position determination of a cylinder piston located in a cylinder liner, said apparatus comprising: a port for coupling an electrical signal into or out of the interior of the cylinder liner, wherein a signal coupled into the interior of the cylinder liner interacts with the cylinder piston. The present disclosure is characterized by a unit for determining the position of the cylinder piston which is connected to the port and which is configured to determine the position of the cylinder piston in the cylinder liner with the aid of a vectorial measurement of a signal decoupled from the cylinder liner.

Abstract: Method for producing and monitoring oral active ingredient films with a base to which a solution containing at least one active ingredient is applied, the method comprising the steps: • metering and mixing the base formulation, • coating the base formulation onto a substrate, so that a strip results • if necessary, drying the base formulation strip coated on the substrate • printing a colorant solution containing at least one active ingredient onto the upper side of the base formulation strip according to the flexographic printing method, • drying the base formulation strip coated on the substrate together with the printed active ingredient solution, • penetrating the base formulation strip coated on the substrate together with the printed active ingredient solution from the upper and/or lower side by means of radiation from a radiation source, • measuring the transmission of the penetrating radiation by means of at least one reception unit on the opposite side of the base formulation strip coated on the subs

Abstract: The invention relates to an at least three-layer transdermal therapy system (TTS), which contains, in particular, rotigotine as an active ingredient. The TTS comprises an active ingredient-containing central layer, which comprises at least one hygroscopic polymer or copolymer, an inner, active ingredient-permeable layer and an outer layer.

Abstract: A filter for generating an audio output signal includes a plurality of audio output signal samples based on two or more input microphone signals. The audio output signal and the two or more input microphone signals are represented in a time-frequency domain, wherein each of the plurality of audio output signal samples is assigned to a time-frequency bin of a plurality of time-frequency bins. The filter includes a weights generator being adapted to receive, for each of the plurality of time-frequency bins, direction-of-arrival information and weighting information. Moreover, the filter includes an output signal generator for generating the audio output signal.

Abstract: It has been found that phenyl carbamates, in particular Rivastigmine, can be formulated as a stable TTS by using a monolayer poly alkyl (meth)acrylates, wherein the poly alkyl (meth)acrylates are substantially free of free carboxylate groups.

Abstract: Method for producing and monitoring oral active ingredient films with a base to which a solution containing at least one active ingredient is applied, the method comprising the steps: • metering and mixing the base formulation, • coating the base formulation onto a substrate, so that a strip results • if necessary, drying the base formulation strip coated on the substrate • printing a colorant solution containing at least one active ingredient onto the upper side of the base formulation strip according to the flexographic printing method, • drying the base formulation strip coated on the substrate together with the printed active ingredient solution, • penetrating the base formulation strip coated on the substrate together with the printed active ingredient solution from the upper and/or lower side by means of radiation from a radiation source, • measuring the transmission of the penetrating radiation by means of at least one reception unit on the opposite side of the base formulation strip coated on the subs

Abstract: The invention relates to a method for determining the piston position of a hydraulic or pneumatic piston cylinder unit, wherein the cylinder jacket and the piston form an electrical conducting path and the piston position is determined with the aid of the inductive and/or resistive properties of the conducting path that is formed. In addition, the invention relates to a piston cylinder unit having a measuring device for carrying out such a method.

Abstract: The present invention pertains to oral applicable therapeutic dosage forms, in particular to orodispersible films. The present invention especially is directed to orodispersible films comprising a base layer substantially free of therapeutically active agents and a top layer comprising the desired therapeutically active agents. The present invention also concerns suitable base layers for such orodispersible films as well as therapeutical uses thereof and methods for manufacturing them.

Abstract: A method for preparing a transdermal patch comprising a substrate layer is provided, the method comprising the steps of contacting an active pharmaceutical ingredient with a retaining means to provide a composition, applying the composition obtained in step (a) to a carrier material to form a substrate layer of the transdermal patch, wherein the retaining means remain within the final transdermal patch.

Abstract: A dermal or transdermal therapeutic system comprising a reservoir that contains at least one active substance, an active substance-permeable membrane which delimits the active-substance reservoir, and a closing layer. The closing layer is impermeable to the active substance at a temperature lying below the skin temperature while being permeable at skin temperature and above.

Abstract: A method for preparing a transdermal patch comprising a substrate layer is provided, the method comprising the steps of contacting an active pharmaceutical ingredient with a retaining means to provide a composition, applying the composition obtained in step (a) to a carrier material to form a substrate layer of the transdermal patch, wherein the retaining means remain within the final transdermal patch.

Abstract: A dermal or transdermal therapeutic system comprising a reservoir that contains at least one active substance, an active substance-permeable membrane which delimits the active-substance reservoir, and a closing layer. The closing layer is impermeable to the active substance at a temperature lying below the skin temperature while being permeable at skin temperature and above.