Abstract: The invention relates to an augmentation device comprising an annular cone surrounding a channel which extends axially along a longitudinal axis of the augmentation device from a proximal cone end to a distal cone end, wherein an outer diameter of the cone decreases from the proximal cone end in the direction of the distal cone end.

Abstract: Systems and methods for assessing a disease are provided. An input medical image in a first modality is received. Lungs are segmented from the input medical image using a trained lung segmentation network and abnormality patterns associated with the disease are segmented from the input medical image using a trained abnormality pattern segmentation network. The trained lung segmentation network and the trained abnormality pattern segmentation network are trained based on 1) synthesized images in the first modality generated from training images in a second modality and 2) target segmentation masks for the synthesized images generated from training segmentation masks for the training images. An assessment of the disease is determined based on the segmented lungs and the segmented abnormality patterns.

Abstract: One aspect relates to a bone cement applicator having a cartridge with an interior, a cartridge head with a delivery opening, a mixing member which is movable in the interior with a mixing rod. A delivery plunger is arranged in the cartridge and is mounted in the interior and is pressable in the direction of the delivery opening. The delivery plunger rests with an outer cylindrical circumferential surface against an inner wall of the cartridge. A clamping element is arranged on the inner wall of the cartridge in the region of a back side of the interior. The clamping element projects out of the inner wall of the cartridge. The cylindrical circumferential surface of the delivery plunger is resiliently deformable by the clamping element in the direction of a central cylinder axis, such that the delivery plunger is clampable in place with the at least one clamping element on the back side of the cartridge.

Abstract: Augmentation material having a wire and, in axial alignment along the wire, a plurality of groups of axially adjacent connecting elements that extend radially from the wire, wherein the connecting elements are designed such that, when a first group from the plurality of groups is pressed together with a further group from the plurality of groups, the connecting element of the two groups can be connected to one another in a positive-locking and/or friction-locking manner.

Abstract: A method, computer system, and a computer-readable medium for registering one or more structures to a desired orientation for planning and guidance for surgery is provided. The method includes in a preoperative stage, obtaining one or more 3D models of one or more structures from one or more CT images using an image processing segmentation technique or a manual segmentation technique; in the preoperative stage, registering the one or more structures to a template that is adapted to an alternating registration for a patient-specific shape and pose for a desired reduction and corresponding reduction transformations; in an intraoperative stage, mapping the one or more structures to one or more radiographs via a 3D-2D registration that iteratively optimizes a similarity metric between acquired and simulated radiographs; and in the intraoperative stage, providing an output that is representative of a radiograph or a 3D tomographic representation to provide guidance to a user.

Abstract: An apparatus for providing a liquid component as a first starting component of a bone cement dough from two starting components, comprising a receptacle in which a tank containing the liquid component can be stored, an opening means for opening the tank, a reservoir, fluidically connected to the receptacle, for receiving the liquid component from the tank, at least one port for fluidically connecting the apparatus to a syringe in which a powder component can be stored as a second starting component of the bone cement dough, and at least one conducting means which fluidically connects the reservoir and the at least one port to one another.

Abstract: A device for providing a bone cement dough from two starting components, comprising a hollow cylindrical cartridge with an interior space, wherein a bone cement powder as the first starting component is stored in a proximal part of the interior space, and at least two pouches containing a monomer liquid as a second starting component are stored in a distal part of the interior space, wherein a dispensing plunger axially movable in the interior space is arranged between the bone cement powder and the at least two pouches, and a delivery plunger axially movable in the interior space is arranged on a side of the at least two pouches that is axially opposite the dispensing plunger, wherein the proximal part and the distal part of the interior space are fluidically connected to one another via a conduit means.

Abstract: The invention relates to an augmentation device comprising an annular cone surrounding a channel extending through the cone from a proximal cone end to a distal cone end of the cone. The invention further relates to an augmentation system comprising such an augmentation device and an applicator, as well as an implantation method of an augmentation device using such an augmentation system.

Abstract: A device and method for applying a pharmaceutical fluid comprising a hollow cylindrical body, which surrounds a channel that extends through the body from a proximal body end to a distal body end of the body, wherein an outer surface of the body has at least partially an external thread, and has a connecting element arranged at the proximal body end, via which a proximal channel end of the channel can be reversibly connected in terms of fluid conduction to a reservoir for the pharmaceutical fluid.

Abstract: A surgical cleaning device and method of use having a housing, a drive shaft rotatably mounted, having a rear end and a front end, a brush head positioned at the front end and arranged outside the housing, to which a plurality of elastically deformable bristles are attached, a pump connected with the drive shaft for pumping a rinsing liquid, a gearbox that is connected with the front end of the drive shaft and with a rear end of the tube and which translates the rotational movement of the drive shaft into an oscillating linear movement of the tube and the brush head, wherein the tube is mounted movable in a linear manner; the brush head in the region of the elastically deformable bristles has at least one ejection opening, wherein the tube opens liquid-permeably through the at least one ejection opening in the direction of the elastically deformable bristles.

Abstract: One aspect relates to a method for providing a bone cement from two starting components, having a hollow cylinder-shaped first container, in which a monomer liquid as first starting component can be stored, a hollow cylinder-shaped second container comprising a container wall, a first internal space, and a second internal space, whereby a bone cement powder as second starting component can be stored in the first internal space, and whereby the monomer liquid can be conveyed into the second internal space, a fluid-conducting conveying means arranged between the first internal space and the second internal space, whereby the first container and the second container are axially connected to each other.

Abstract: A device and method for producing a bone cement paste from a monomer liquid and a cement powder, wherein the device comprises a cartridge with a cylindrical interior chamber for mixing the parent components, whereby the interior chamber of the cartridge is closed on the front side up to a delivery opening for expelling the bone cement paste from the interior chamber, a delivery plunger which is arranged in the interior chamber of the cartridge and which is supported in a linearly movable manner in the direction of the delivery opening, the cement powder, which is arranged in the interior chamber of the cartridge between the delivery opening and the delivery plunger, a monomer receptacle with an interior chamber in which a monomer liquid container containing the monomer liquid is contained, whereby in the monomer receptacle, a conveying plunger is arranged movable in the longitudinal direction of the monomer receptacle, a compressed gas connection, whereby the conveying plunger is arranged between the monomer

Abstract: The invention relates to a device for applying a pharmaceutical fluid, having a tube and a valve element, wherein the tube can be connected in terms of fluid conduction via a first tube end to a reservoir for the pharmaceutical fluid, and wherein the valve element is arranged in a second tube end of the tube. The invention furthermore relates to a system for applying a pharmaceutical fluid, having a reservoir for the pharmaceutical fluid and such a device, and to a method for applying a pharmaceutical fluid by means of such a device.

Abstract: One embodiment is a medical device with a flexibly deformable external hose. The external hose includes multiple openings, at least one of them arranged in a first end of the external hose. It includes a flexible internal hose, which is arranged on the inside of the external hose. The internal hose, in an expanded state, has an external diameter that is at least equal to the internal diameter of the external hose, closing the openings of the external hose. The external diameter of the internal hose can be transitioned from the expanded state into a radially contracted state, exposing the openings. A connection firmly connects the external hose and the internal hose on the first end of the external hose, and closes them in fluid-tight manner. A connector supplies the fluid into the intervening space between the external and the internal hose.

Abstract: A medical implant for treating bone defects. The implant has at least one hollow body delimiting an inner chamber in the interior of the hollow body, a fluid feed line connected in a fluid-permeable manner with the inner chamber, and a fluid discharge line connected in a fluid-permeable manner with the inner chamber. The hollow body consists at least in places or wholly of at least one plastic material that is impermeable to liquids and permeable to oxygen and to carbon dioxide, such that oxygen is deliverable from a fluid passed through the hollow body to, and carbon dioxide is absorbable into the fluid from, the surroundings of the hollow body. Also disclosed is a bone defect treatment system having such a medical implant and the fluid, wherein the fluid contains oxygen and is suitable for absorbing oxygen, and to a method for gas-flushing a surface of a medical implant.

Abstract: One aspect relates to a device for providing a bone cement from two starting components, having a hollow cylinder-shaped first container, in which a monomer liquid as first starting component can be stored, a hollow cylinder-shaped second container comprising a container wall, a first internal space, and a second internal space, whereby a bone cement powder as second starting component can be stored in the first internal space, and whereby the monomer liquid can be conveyed into the second internal space, a fluid-conducting conveying means arranged between the first internal space and the second internal space, whereby the first container and the second container are axially connected to each other.

Abstract: Device for the mixing of polymethylmethacrylate bone cement and for storing a monomer liquid and a cement powder as starting components of the bone cement, comprising a cartridge having an internal space closed on one side by a mobile dispensing plunger; a monomer container for a monomer liquid and/or a connector for attachment of a monomer container which can be opened in the device so that the monomer liquid flows from the monomer container into the device; and a connecting conduit through which the monomer liquid can be guided into the internal space of the cartridge; having a pumping plunger that can be shifted axially in the hollow cylinder arranged in the hollow cylinder, which can be used to push monomer liquid from the hollow cylinder through the connecting conduit into the internal space of the cartridge by actuating the pumping plunger.

Abstract: One embodiment relates to a device for the production of a bone cement dough from a monomer liquid and a cement powder comprising a cartridge with an internal space; a cartridge head with a dispensing opening; a conveying plunger that is arranged in the internal space of the cartridge and is supported in the internal space of the cartridge such that it is pushable in the direction of the dispensing opening; a dispensing plunger between the dispensing opening and the conveying plunger that is supported in the internal space of the cartridge such that it is pushable in the direction of the dispensing opening; a first hollow space, in which the cement powder is arranged; a second hollow space that is bordered by the dispensing plunger and the conveying plunger; a fluid opening that is arranged in the conveying plunger; a feedthrough that connects the first hollow space and the second hollow space to each other, and a closure means that is arranged on a rear side of the dispensing plunger.

Abstract: The invention relates to a method for producing a bone cement with a device comprising a cartridge (1) having a cylindrical interior (2), cement powder (6), and monomer liquid (7) in a monomer liquid container (8), a cartridge head (3) having a discharge opening (9), a closure (10) in the discharge opening (9), which closure is permeable to gases and impermeable to powder particles, a drive piston (5), and a central piston (4), wherein the central piston (4) is permeable to gases and the monomer liquid (7) and impermeable to the powder particles of the cement powder (6) and is arranged between the drive piston (5) and the cartridge head (3), wherein the central piston (4) separates the interior (2) into a first cavity (12) and a second cavity (14), the method comprising the following steps: A) moving the drive piston (5) toward the cartridge head (3), B) opening the monomer liquid container (8) via the movement of the drive piston (5) and releasing the monomer liquid (7) in the second cavity (14), C) expell

Abstract: Systems and methods for generating a synthetic image are provided. An input medical image in a first modality is received. A synthetic image in a second modality is generated from the input medical image. The synthetic image is upsampled to increase a resolution of the synthetic image. An output image is generated to simulate image processing of the upsampled synthetic image. The output image is output.