Abstract: Bone cement applicators and methods for application of a bone cement dough, the applicators and methods comprise a tubular cartridge with an internal space, a dispensing plunger for expelling the starting components through an opening of the cartridge opposite from the dispensing plunger, wherein the dispensing plunger is mobile in longitudinal direction in the internal space of the cartridge. The applicators and methods further comprise a hose, an application opening, a three-way valve operable from outside and arranged or arrangeable in the hose or on a side of the hose facing the cartridge, and a collecting container arranged on the three-way valve.

Abstract: A device and methods mix polymethylmethacrylate bone cement and/or store the starting components of the bone cement. The device comprising: a cartridge with an internal space for mixing the bone cement that is closed on one side by means of a mobile dispensing plunger; a monomer container for a monomer liquid and/or a connector for attachment of a monomer container for a monomer liquid such that the monomer container can be opened appropriately in the device such that the monomer liquid flows from the monomer container into the device; a connecting conduit through which the monomer liquid can be guided into the internal space of the cartridge.

Abstract: Devices and methods manually open glass ampules within the devices. One device may include a holder having at least one deformable side wall, a supporting element, and at least one strainer/filter arranged below the holder so that the content of the opened glass ampule may flows therethrough. A first lever of the device may pivot around a first axis and a free end of the first lever may be pressed against the deformable side wall of the holder. A second lever of the device may pivot around a second axis that may divide the second lever into a short lever arm and a long lever arm. The short lever arm may be pressed against the first lever and a glass ampule may be broken open by pressure of the free end of the first lever.

Abstract: A bone cement applicator comprising a cartridge with an internal space. The cartridge has a head with a dispensing opening for expulsion of bone cement, a first thread, a dispensing plunger, a threaded tube having a counter thread engaging the first thread, a receptacle mobile in the threaded tube, and a mixing rod with a mixer fastened to it and arranged in the internal space of the cartridge. The mixing rod is detachably connected to the receptacle and is guided through a feedthrough in the dispensing plunger and is supported in the feedthrough so as to be axially mobile. When detached from the receptacle, the mixing rod can be pushed into the receptacle when the receptacle is propelled in the direction of the cartridge head. A method is also disclosed for production of a bone cement using the bone cement applicator.

Abstract: A bone cement applicator comprising a cartridge with an internal space. The cartridge has a head with a dispensing opening for expulsion of bone cement, a dispensing plunger, a receptacle mobile in the cartridge, and a mixing rod with a mixer fastened to it and arranged in the internal space of the cartridge. The mixing rod is detachably connected, on a side opposite from the mixer, to a front side of the receptacle that faces the cartridge head. When the mixing rod is detached from the receptacle and the receptacle is propelled in the direction of the cartridge head the mixing rod can be pushed into the receptacle. A method is also disclosed for production of a bone cement using the bone cement applicator.

Abstract: A pasty two-component polymethacrylate bone cement comprising a pasty component A, containing AI at least one distillable methacrylate monomer for radical polymerisation; AII at least one polymer soluble in AI; AIII at least one particulate polymer with a particle size of no more than 500 ?m that is not soluble in AI; AIV at least one radical stabiliser; and AV at least one aromatic amine accelerator; and a pasty component B, containing BI dibenzoyl peroxide; BII at least one substance that is not subject to radical polymerisation and is liquid at room temperature, whereby the solubility of dibenzoyl peroxide in this substance at room temperature is less than 5.0% by weight and, whereby the weight fraction of liquid substance BII in the self-curing cement dough is less than 2.0% by weight. Also disclosed is a method for producing a self-curing bone cement dough using the pasty two-component polymethacrylate bone cement.

Abstract: A vacuum motor has a piston that linearly oscillates in the internal space of a housing. A gas outlet and a gas inlet (supplying ambient air) located in the housing terminate in the space between the piston and the housing rear side. The piston never covers the outlet or inlet. A valve body closes the inlet. A pestle moves within the housing between the piston and valve body. When the piston moves toward the rear side of the space, the valve body moves against the force of a spring and opens the inlet. The free cross-section of the opened inlet is at least equal in size to the free cross-section of the outlet. A surgical drive system, a medical lavage system, and a medical device for brushing, rasping or sawing of tissue or bone—all include the vacuum motor. Also disclosed is a method for operating the vacuum motor.

Abstract: Opening device for the opening of a monomer liquid container (1) comprising a positioning aid (6) for positioning of the monomer liquid container (1), an opening facility (8) for the opening of the monomer liquid container (1), the opening facility (8) being mobile with respect to the positioning aid (6) and/or the positioning aid (6) being mobile with respect to the opening facility (8), at least one elastically deformable energy-storing element (9) for storage of elastic energy, whereby a motion of the opening facility (8) and/or a motion of the positioning aid (6) can be driven by the elastic energy of the at least one elastically deformable energy-storing element (9).

Abstract: The invention proposes a polymer solution for visco-supplementation. The polymer solution contains at least one at least partially water-soluble polysaccharide or polysaccharide derivative, one water-soluble alkali salt or alkaline earth salt of polystyrene sulfonic acid, and water, whereby the polymer solution is clear to the eye. Moreover, the invention describes a method for sterilization of the polymer solution. This method is characterized in that a mixture of at least one at least partially water-soluble polysaccharide or polysaccharide derivative, one water-soluble alkali salt or alkaline earth salt of polystyrene sulfonic acid, and water is mixed with at least 0.5 wt. % ß-propiolactone, and in that the polymer solution is stored at room temperature for at least 24 hours.

Abstract: Storage and mixing systems for pasty two-component polymethyl methacrylate bone cements comprise a tubular cartridge having a cylindrical inner chamber, a cartridge head, which closes one end of the tubular cartridge at the front side, a partition that is disposed axially in the cylindrical inner chamber of the cartridge. The partition divides the cylindrical inner chamber of the cartridge bounded by the cartridge head into two cavities that are spatially separated from one another, wherein a first pasty cement component is present in the first cavity and a second pasty cement component is present in the separate second cavity.

Abstract: An antibiotic polymethylmethacrylate bone cement that is composed of methylmethacrylate, at least one polymethylmethacrylate or a polymethylmethacrylate-copolymer, at least one polymerisation initiator, such as in radical initiator, at least one polymerisation accelerator, and at least one radiopaquer, whereby the components are present in a powdered component and a liquid monomer component or in two components that are pasty at room temperature. The polymethylmethacrylate bone cement comprises the cyclical lipopeptide, daptomycin, a pharmacologically tolerable salt of daptomycin, a solvate and/or a hydrate containing daptomycin and at least one calcium salt, which preferably comprises at least two different release profiles. The bone cement is useful in one-stage or two-stage septic revision surgery.

Abstract: A femoral hip joint spacer including a prosthesis body having a ball head with a sliding surface, a neck, a collar and a stem. A fastening area is arranged on the stem. The femoral hip joint spacer further has a first connector for feeding a medical irrigation liquid into the body, a second connector for draining the irrigation liquid from the body, and an irrigation liquid inlet opening. The first connector is connected in a liquid-conveying manner to the irrigation liquid inlet opening and an irrigation liquid outlet opening. The second connector is connected in a liquid-conveying manner to the irrigation liquid outlet opening, an irrigation liquid discharge opening and an irrigation liquid intake opening. The irrigation liquid discharge opening is connected inside the body to the irrigation liquid inlet opening and the irrigation liquid intake opening is connected inside the body to the irrigation liquid outlet opening.

Abstract: Disclosed herein is a temporary knee spacer system for the temporary replacement of a knee joint, which is designed for the interim phase of two-stage septic revisions of knee joint total endoprostheses. The knee spacer system can be used in particular with two-phase septic revisions with which two or more microbial germs are the cause of an infection of the knee joint total endoprosthesis and the surrounding tissue.

Abstract: A spacer mold and method for producing a hip spacer, the spacer mold comprises a base element (1), in which a hollow mold is provided as negative image of one side of a femoral stem of the spacer to be generated, whereby a recess connected to the hollow mold is arranged on the proximal end of the hollow mold in the base element. The spacer mold further comprises a semi-spherical insert (2) comprising a femoral head mold as negative image of one side of a femoral head of the spacer to be generated, whereby the semi-spherical insert (2) is to be arranged in the recess in the base element (1). Further, the spacer mold comprises an adapter insert (3) that is designed as a hollow body that is open on two sides and that is or can be arranged in the recess of the base element (1) between the semi-spherical insert (2) and the hollow mold such that the recess exerts a pressure onto the adapter insert (3) and the semi-spherical insert (2).

Abstract: A device for producing a bone cement dough from a monomer liquid and a cement powder and dispensing the bone cement dough. The device includes a cartridge holding the cement powder in an internal space. A monomer receptacle screws onto the cartridge, forms a chamber, and has a plunger with a passage that is permeable to gases and the monomer liquid but is impermeable to the cement powder and that connects the internal space to the chamber. The plunger tightly closes the internal space with the exception of the passage. A gas supply opening is arranged in the wall of the monomer receptacle. A monomer liquid container holds the monomer liquid and is located in the chamber. An opening facility opens the container, and closes the gas supply opening before opening the container. Also provided is a method for producing and dispensing the bone cement dough.

Abstract: A methods and mixtures are provided for sterilization of a polymerizable monomer, in which the mixture contains at least the polymerizable monomer, a compound (a), and a compound (b). Compound (a) is selected from the group of compounds (a1), compounds (a2), and compounds (a3), wherein compounds (a1) are represented by general formula (I): wherein R1, R2, R3, and R4, independent of each other, represent a substituted alkyl residue, a non-substituted alkyl residue, a halogen, a nitro group, or a cyano group; compounds (a2) are selected from the group of dimers of compounds (a1); and compounds (a3) are selected from the group of dialkyldicarbonates. Compound (b) is selected from the group of water and alcohols.

Abstract: A paste application device stores two starting components for mixing the starting components to form a paste and for application of the formed paste. The device comprises a two-component cartridge comprising two internal spaces, two feed plungers shiftable in the internal spaces and bordering the internal spaces on a first side of the two-component cartridge, and at least two dispensing openings by means of which the internal spaces are open on a second side of the two-component cartridge that is opposite from the first side.

Abstract: An implant is provided having an antibiotic coating that is inexpensive and easy to manufacture. The antibiotic coating adheres well and in stable manner to the surface of the implant, can be degraded by the body without forming toxic products, prevents the crystallization of the antibiotics in the coating, and ensures a high immediate locally-effective antibiotic concentration at the implant site. A coating solution useful for making the implant and a method for the manufacture of the implant are also described.

Abstract: One aspect relates to a device to produce a bone cement paste from a monomer liquid and a cement powder as starting components of the bone cement paste, and to dispense the mixed bone cement paste.

Abstract: An antiseptic composition for use as bone cement, in particular an antiseptic polymethylmethacrylate bone cement. The composition can be cured and comprises a pharmacologically tolerable salt of a monoperoxy dicarboxylic acid, whereby the salt of the monoperoxy dicarboxylic acid can be dissolved from the composition in the presence of water. Preferably, the salt of the monoperoxy dicarboxylic acid in the composition is used in the form of a powder, whereby the powder has a mean particle size of not more than 250 ?m. Preferably, the salt of the monoperoxy dicarboxylic acid, in solution at room temperature, is not degraded within 5 min by the catalase enzyme.