Abstract: Devices and methods mix a bone cement and comprise at least one cartridge, wherein the cartridge comprises in its interior a cylindrical mixing chamber, a discharge piston movable in the cylindrical mixing chamber in the longitudinal direction and sealable against the walls of the mixing chamber, a mixing device for thoroughly mixing the content of the mixing chamber, which is arranged in the interior of the mixing chamber. The mixing device is operable externally via a mixing rod and the mixing rod is guided through a passage in the discharge piston such that it can be rotated and displaced in the longitudinal direction by the discharge piston. The cartridge comprises a discharge opening opposite the discharge piston, wherein, in the mixing chamber, a first component is contained between the discharge piston and the discharge opening, wherein a monomer fluid as a second component is introducable through the discharge opening into the mixing chamber.

Abstract: Sterilization method according to which an aqueous polysaccharide solution is stored in the presence of a lactone and a buffer system for a period of at least 24 hours, and a sterile polysaccharide solution produced in this way.

Abstract: A vacuum mixing system for the mixing of polymethylmethacrylate bone cement comprising at least one cartridge (4) having an evacuatable internal space (5) for the mixing of the bone cement, the internal space (5) of which comprises a cylindrical swept volume, a mixing element (12) that is arranged in the internal space (5) of the cartridge (4) such as to be mobile and can be operated from outside the vacuum mixing system in order to mix the content in the internal space (5) of the cartridge (4), and a dispensing plunger (2) having a cylindrical external circumference whose first base surface borders a base surface of the internal space (5) of the cartridge (4) and which can be or is locked to the cartridge (4) in detachable manner and which, in the detached state, is mobile in the cylindrical region of the internal space (5) of the cartridge (4).

Abstract: A medical spraying device and method for irrigating a wound, in particular lavage system, having a liquid reservoir for a medical irrigation liquid or a connection for such a liquid reservoir, and a compressed gas reservoir. The compressed gas reservoir is connected or connectable via a pressure line to the liquid reservoir, such that the irrigation liquid can be pushed by the gas pressure of the compressed gas reservoir acting on the irrigation liquid through a nozzle in order to produce a spray cone. A pressure reduction valve is arranged in the pressure line and limits the gas pressure acting in the liquid reservoir on the irrigation liquid. The device and method produce a spray cone of a medical irrigation liquid in which a gas pressure is limited using a pressure reduction valve, wherein the gas pressure limited by the pressure reduction valve is conveyed through a pressure line to a liquid reservoir of the medical irrigation liquid.

Abstract: A polymerizable polymethylmethacrylate bone cement, in which the initial viscosity of the cement dough can be controlled. The polymerizable bone cement composition comprises a monomer for radical polymerization, a powdered polymethylmethacrylate-co-polymer soluble in the monomer or a mixture comprising polymethylmethacrylate-co-polymers, a polymerization initiator, and a radiopaquer, wherein the powdered polymethylmethacrylate-co-polymer comprises at least one particulate polymethylmethacrylate-co-polymer having a molar mass of more than or equal to 200,000 g/mol, and the polymethylmethacrylate-co-polymer is obtainable by polymerization of a mixture of 90.0% or more by weight methylmethacrylate and 10.0% or less by weight of one or more comonomers, wherein the weight ratio of component A comprising the polymethylmethacrylate-co-polymer, radiopaquer, and polymerization initiator, and component B comprising a monomer for radical polymerization, stabilizer, and polymerization accelerator, is approximately 2.

Abstract: A storage and mixing system for pasty two-component polymethyl methacrylate bone cements comprises a tubular cartridge with a cylindrical interior, a cartridge head that closes one end of the tubular cartridge, a partition wall axially disposed in the cylindrical interior and dividing the cylindrical interior into two spatially separate cavities, the first cavity including a first pasty cement component and the second cavity including a second pasty cement component, two delivery plungers disposed movably in the two cavities and connected via a connecting means, wherein a wedge or cone having a cutting edge on the front side thereof facing the cartridge head is disposed on the connecting means, such that said cutting edge cuts open the partition wall when the delivery pistons are advanced towards the cartridge head and the wedge or cone presses the cut open parts of the partition wall towards the inner wall of the cartridge.

Abstract: A storage and mixing system, for pasty two-component polymethyl methacrylate bone cements, comprises a cartridge with a cylindrical interior, a cartridge head that closes an end of said cartridge, a partition wall axially disposed in the cylindrical interior of the cartridge, wherein said partition wall is connected to the circumferential surface of the cylindrical interior of the cartridge and divides the cylindrical interior of the cartridge delimited by the cartridge head into two spatially separate cavities. The first cavity includes a first pasty cement component and the separate second cavity includes a second pasty cement component, two delivery plungers close the two cavities on the side of the cavities opposite the cartridge head.

Abstract: The invention relates to a device and method for producing a bone cement paste (54) from a monomer liquid (4) and a cement powder (5).

Abstract: Paste application system having a two-component cartridge with two axially shiftable feed plungers; one hollow cylinder with an open front face and an at least partially closed front face, an axially mobile first plunger situated therein with two pestles attached to it; another hollow cylinder that contains a manually shiftable second plunger; and a liquid container, whereby the second hollow cylinder is connected or connectable to the liquid container in liquid-permeable manner by a first conduit means and a first non-return valve, and the first hollow cylinder is connected or connectable to the second hollow cylinder in liquid-permeable manner by a second conduit means and a second non-return valve; whereby the two-component cartridge and the first hollow cylinder, arranged axially adjacent, with the axially mobile pestles are arranged in a pressure container; and the paste application system contains a hollow space and liquid is present in said space.

Abstract: Storage and mixing systems and methods for pasty multicomponent polymethylmethacrylate bone cements, the systems and methods comprise a first tubular cartridge with a first cylindrical internal space containing a first starting component, a first dispensing plunger, a second tubular cartridge that is arranged within the first tubular cartridge. The external wall of the second cartridge touches against the internal wall of the first cartridge and is attached to the internal wall of the first cartridge, whereby the second cartridge contains a second starting component and has a second dispensing plunger arranged in it, whereby a pressing device with a clamping edge for compressing the second cartridge that can be propelled axially in the internal space of the first cartridge is arranged, as seen from the cartridge head, behind the first dispensing plunger and the second dispensing plunger.

Abstract: One aspect relates to a device for producing a bone cement paste from a monomer liquid and a cement powder and for delivering the bone cement paste, the device having a cartridge with a cylindrical interior, the interior of the cartridge being closed at the front side apart from a delivery opening for discharging the bone cement paste from the interior. A delivery plunger is arranged in the interior of the cartridge and mounted so as to be pushable in the direction of the delivery opening. The cement powder is arranged in the interior of the cartridge between the delivery opening and the delivery plunger. A closure closes the delivery opening and is mounted so as to be movable relative to the delivery opening. A line element is arranged at the front side of the delivery opening and includes a closure receptacle for receiving at least part of the closure.

Abstract: A device mixes bone cement and stores parent components of the bone cement. The device has a cartridge comprising an interior, that is closed on one side by a movable delivery plunger, a receptacle comprising side walls for receiving a monomer liquid container that are closed at least in some regions. The receptacle has at least one deformable closed side wall, a screen and/or a filter arranged below the receptacle so that the contents of the opened monomer liquid container flow through the screen and/or the filter. The device further has a connecting line through which the monomer liquid is to be routed into the interior of the cartridge, a hollow cylinder which is connected to the connecting line and which is connected to the receptacle by way of a fluid connection so that the hollow cylinder is arranged in a fluid line between the receptacle and the interior of the cartridge.

Abstract: A malleable, biodegradable hemostatic agent is provided that can be used for mechanical sealing of bleeding bone tissue, as well as a method for forming a malleable, biodegradable hemostatic agent of this type, and a medical implant having a coating that includes a malleable, biodegradable hemostatic agent of this type. The malleable, biodegradable hemostatic agent contains (a) at least one saturated glycerol-1,2,3-tri-fatty acid ester having a melting temperature above 37° C., (b) at least one filling agent present in particulate form, at least in part, and having a melting temperature above 37° C., and (c) at least one compound having a melting temperature not above 37° C. and a solubility at a temperature of 25° C. of less than 50 grams per liter of water.

Abstract: One aspect relates to a device for producing a bone cement paste from a monomer liquid and a cement powder as parent components of the bone cement paste and for delivering the mixed bone cement paste. The device has a cartridge with a cylindrical interior. The interior of the cartridge is closed at a front side apart from a delivery opening for discharging the bone cement paste. In the interior of the cartridge a delivery plunger is arranged which is pushable in the direction of the delivery opening. The cement powder is arranged in the interior of the cartridge between the delivery opening and the delivery plunger. A hollow cylinder is arranged at a front side of the delivery plunger facing the delivery opening. The hollow cylinder is open at its front face facing the delivery opening and extends from the front side of the delivery plunger at least 3 mm into the interior of the cartridge.

Abstract: A vacuum mixing system for the mixing of polymethylmethacrylate bone cement, comprising at least one cartridge (4) having an evacuable internal space for mixing of the bone cement, a pump (18) for generating a negative pressure, and a connecting conduit (12) connecting the internal space of the at least one cartridge (4) to the pump (18) for generating a negative pressure, an integrated energy reservoir (28) for driving the pump (18) that is or can be connected to the pump (18) and has energy for at least one pumping process of the pump (18) stored in it, whereby a negative pressure can be generated by means of the pump (18) during the pumping process, which negative pressure can be used to evacuate gas from the internal space of the at least one cartridge (4) through the connecting conduit (12).

Abstract: Particulate alloplastic bone replacement material and methods have a multitude of particles, wherein the particles have a core and at least six pins extending from the core, wherein the pins each have at least one connecting element, and wherein the pins are deformable elastically such that, upon multiple particles being pressed together, the connecting elements of different particles interlock with and/or snap into each other and the particles that are interlocked with and/or snapped into each other form an open-pored body of particles that are interlocked with and/or snapped into each other.

Abstract: Device for the mixing of polymethylmethacrylate bone cement and for storing a monomer liquid and a cement powder as starting components of the bone cement, comprising a cartridge having an internal space closed on one side by a mobile dispensing plunger; a monomer container for a monomer liquid and/or a connector for attachment of a monomer container which can be opened in the device so that the monomer liquid flows from the monomer container into the device; and a connecting conduit through which the monomer liquid can be guided into the internal space of the cartridge; having a pumping plunger that can be shifted axially in the hollow cylinder arranged in the hollow cylinder, which can be used to push monomer liquid from the hollow cylinder through the connecting conduit into the internal space of the cartridge by actuating the pumping plunger.

Abstract: One aspect relates to a device for producing a bone cement paste from a monomer liquid and a cement powder as parent components of the bone cement paste and for delivering the mixed bone cement paste, the device having a cartridge having a cylindrical interior. The interior of the cartridge is closed on the front side except for a delivery opening for expelling the bone cement paste. A delivery plunger is arranged in the interior of the cartridge. The cement powder is arranged in the interior of the cartridge. A closure is arranged on the front side of the delivery plunger. The closure closes the delivery opening when the delivery plunger is pressed against the front side of the interior of the cartridge.

Abstract: A manually drivable device for the mixing of a pasty mixing ware from at least two fluid starting components comprising at least two cartridges having feed plungers; a mixing space to mix the starting components, mixing vanes being provided in the mixing space and mounted such that they can rotate; a lever rotatable about a pivot point operatable manually or a pin that can be shifted in longitudinal direction and operatable manually in order to operate the device; a gear connected to the lever or pin, and connected to the rotatable mixing vanes in the mixing space; and a facility for propelling the feed plungers such that the motion of the lever or pin drives the rotation of the mixing vanes in the mixing space and motion of the feed plungers into the cartridges. The invention also relates to a method for mixing fluid starting components using the device.

Abstract: A device for storage of a monomer liquid and a cement powder as starting components of a bone cement dough and for mixing the starting components, and for dispensing the mixed bone cement dough. The device includes a receptacle in which a monomer liquid container is arranged and a cartridge containing the cement powder. A feed plunger is arranged in the receptacle. A dispensing plunger is arranged between the monomer liquid container and the cement powder in the cartridge. The feed plunger can be punctured by a rod when motion of the feed plunger is blocked, whereby the dispensing plunger is propelled by propelling the rod further through the blocked and punctured feed plunger. Also provided are an extrusion device for propelling a feed plunger and a dispensing plunger of a device for mixing of a bone cement dough, and a method for the production of a bone cement dough.