Patents by Inventor Seetharamaiyer Padmanabhan

Seetharamaiyer Padmanabhan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds,compositions, and methods for the treatment of disease
    Patent number: 11744845
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Grant
    Filed: June 4, 2021
    Date of Patent: September 5, 2023
    Assignee: F-star Therapeutics, Inc.
    Inventors: Radhakrishnan P. Iyer, Anjaneyulu Sheri, Seetharamaiyer Padmanabhan, Geeta Meher, Shenghua Zhou, Sreerupa Challa, Rayomand H. Gimi, Dillon Cleary
  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
    Publication number: 20230271999
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Application
    Filed: January 20, 2023
    Publication date: August 31, 2023
    Inventors: Radhakrishnan P. Iyer, Geeta Meher, Anjaneyulu Sheri, Shenghua Zhou, Sreerupa Challa, Rayomand H. Gimi, Seetharamaiyer Padmanabhan, Dillon Cleary
  • Compounds, compositions, and methods for the treatment of disease
    Patent number: 11584774
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Grant
    Filed: September 11, 2018
    Date of Patent: February 21, 2023
    Assignee: F-star Therapeutics, Inc.
    Inventors: Radhakrishnan P. Iyer, Geeta Meher, Anjaneyulu Sheri, Shenghua Zhou, Sreerupa Challa, Rayomand H. Gimi, Seetharamaiyer Padmanabhan, Dillon Cleary
  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
    Publication number: 20220168309
    Abstract: Disclosed are compounds and compositions for inhibiting the expression of a pattern recognition receptor (e.g., STING), and methods of use thereof.
    Type: Application
    Filed: March 5, 2020
    Publication date: June 2, 2022
    Inventors: RADHAKRISHNAN P. IYER, SEETHARAMAIYER PADMANABHAN, SUBRAMANIAN BASKARAN, ANJANEYULU SHERI, DILLON CLEARY, RON MASTROLIA, SHENGHUA ZHOU, SREERUPA CHALLA, RAYOMAND H. GIMI, VISHAL NAIR, LEENA PRABA SUPPIAH
  • COMPOUNDS,COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
    Publication number: 20220054523
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Application
    Filed: June 4, 2021
    Publication date: February 24, 2022
    Inventors: Radhakrishnan P. Iyer, Anjaneyulu Sheri, Seetharamaiyer Padmanabhan, Geeta Meher, Shenghua Zhou, Sreerupa Challa, Rayomand H. Gimi, Dillon Cleary
  • Compounds,Compositions, and methods for the treatment of disease
    Patent number: 11033569
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Grant
    Filed: July 6, 2017
    Date of Patent: June 15, 2021
    Assignee: Sperovie Biosciences, Inc.
    Inventors: Radhakrishnan P. Iyer, Anjaneyulu Sheri, Seetharamaiyer Padmanabhan, Geeta Meher, Shenghua Zhou, Sreerupa Challa, Rayomand H. Gimi, Dillon Cleary
  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
    Publication number: 20200270299
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Application
    Filed: September 11, 2018
    Publication date: August 27, 2020
    Inventors: Radhakrishnan P. Iyer, Geeta Meher, Anjaneyulu Sheri, Shenghua Zhou, Sreerupa Challa, Rayomand H. Gimi, Seetharamaiyer Padmanabhan, Dillon Cleary
  • NUCLEOTIDE AND OLIGONUCLEOTIDE PRODRUGS
    Publication number: 20200087338
    Abstract: The present invention discloses compounds of formula (I): which exhibit antiviral properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of anti-HBV treatment. The invention also relates to methods of treating a HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Application
    Filed: May 23, 2019
    Publication date: March 19, 2020
    Inventors: Radhakrishnan P. Iyer, Seetharamaiyer Padmanabhan
  • COMPOUNDS, COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
    Publication number: 20190292215
    Abstract: Disclosed are compounds and compositions for the induction of expression of a pattern recognition receptor (e.g., STING) and methods of use thereof.
    Type: Application
    Filed: July 14, 2017
    Publication date: September 26, 2019
    Inventors: Radhakrishnan P. Iyer, Seetharamaiyer Padmanabhan, Dillon Cleary, Geeta Meher, Rayomand H. Gimi, Anjaneyulu Sheri, Shenghua Zhou, Sreerupa Challa
  • COMPOUNDS,COMPOSITIONS, AND METHODS FOR THE TREATMENT OF DISEASE
    Publication number: 20190262372
    Abstract: Disclosed are compounds and compositions for the activation or induction of expression of a pattern recognition receptor (e.g., STING, RIG-I, MDA5), and methods of use thereof.
    Type: Application
    Filed: July 6, 2017
    Publication date: August 29, 2019
    Inventors: Radhakrishnan P. Iyer, Anjaneyulu Sheri, Seetharamaiyer Padmanabhan, Geeta Meher, Shenghua Zhou, Sreerupa Challa, Rayomand H. Gimi, Dillon Cleary
  • Compositions and methods for treating viral infections
    Patent number: 10376533
    Abstract: The present invention provides compositions methods for treating susceptible viral infections, especially hepatitis C viral (HCV) infections as well as co infections of HCV with other viruses such as HBV and/or HIV. In one embodiment, the present invention provides compositions having the formula (I) and their use in treating viral infections: or a pharmaceutically acceptable salt, ester, stereoisomer, tautomers, solvate, prodrug, or combination thereof.
    Type: Grant
    Filed: December 2, 2016
    Date of Patent: August 13, 2019
    Assignee: Spring Bank Pharmaceuticals, Inc.
    Inventors: Radhakrishnan P. Iyer, Seetharamaiyer Padmanabhan
  • Nucleotide and oligonucleotide prodrugs
    Patent number: 10344046
    Abstract: The present invention discloses compounds of formula (I): which exhibit antiviral properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of anti-HBV treatment. The invention also relates to methods of treating a HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Grant
    Filed: March 15, 2018
    Date of Patent: July 9, 2019
    Assignee: Spring Bank Pharmaceuticals, Inc.
    Inventors: Radhakrishnan P. Iyer, Seetharamaiyer Padmanabhan
  • NUCLEOTIDE AND OLIGONUCLEOTIDE PRODRUGS
    Publication number: 20180273574
    Abstract: The present invention discloses compounds of formula (I): which exhibit antiviral properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of anti-HBV treatment. The invention also relates to methods of treating a HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Application
    Filed: March 15, 2018
    Publication date: September 27, 2018
    Inventors: Radhakrishnan P. Iyer, Seetharamaiyer Padmanabhan
  • Nucleotide and oligonucleotide prodrugs
    Patent number: 10047114
    Abstract: The present invention discloses compounds of formula (I): which exhibit antiviral properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of anti-HBV treatment. The invention also relates to methods of treating a HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Grant
    Filed: November 12, 2015
    Date of Patent: August 14, 2018
    Assignee: Spring Bank Pharmaceuticals, Inc.
    Inventors: Radhakrishnan P. Iyer, Seetharamaiyer Padmanabhan
  • COMPOSITIONS AND METHODS FOR THE TREATMENT OF VIRAL INFECTION
    Publication number: 20180185404
    Abstract: This invention relates to compositions and methods for the treatment of infection such as RSV, influenza, adenovirus, or rhinovirus.
    Type: Application
    Filed: July 1, 2016
    Publication date: July 5, 2018
    Inventors: Radhakrishnan P. IYER, Seetharamaiyer PADMANABHAN
  • COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTIONS
    Publication number: 20170304344
    Abstract: The present invention provides compositions methods for treating susceptible viral infections, especially hepatitis C viral (HCV) infections as well as co infections of HCV with other viruses such as HBV and/or HIV. In one embodiment, the present invention provides compositions having the formula (I) and their use in treating viral infections: or a pharmaceutically acceptable salt, ester, stereoisomer, tautomers, solvate, prodrug, or combination thereof.
    Type: Application
    Filed: December 2, 2016
    Publication date: October 26, 2017
    Inventors: Radhakrishnan P. Iyer, Seetharamaiyer Padmanabhan
  • Compositions and methods for treating viral infections
    Patent number: 9539276
    Abstract: The present invention provides compositions methods for treating susceptible viral infections, especially hepatitis C viral (HCV) infections as well as co infections of HCV with other viruses such as HBV and/or HIV. In one embodiment, the present invention provides compositions having the formula (I) and their use in treating viral infections: or a pharmaceutically acceptable salt, ester, stereoisomer, tautomers, solvate, prodrug, or combination thereof.
    Type: Grant
    Filed: August 11, 2015
    Date of Patent: January 10, 2017
    Assignee: SPRING BANK PHARMACEUTICALS, INC.
    Inventors: Radhakrishnan P. Iyer, Seetharamaiyer Padmanabhan
  • NUCLEOTIDE AND OLIGONUCLEOTIDE PRODRUGS
    Publication number: 20160060287
    Abstract: The present invention discloses compounds of formula (I): which exhibit antiviral properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of anti-HBV treatment. The invention also relates to methods of treating a HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.
    Type: Application
    Filed: November 12, 2015
    Publication date: March 3, 2016
    Inventors: Radhakrishnan P. Iyer, Seetharamaiyer Padmanabhan
  • COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTIONS
    Publication number: 20160038527
    Abstract: The present invention provides compositions methods for treating susceptible viral infections, especially hepatitis C viral (HCV) infections as well as co infections of HCV with other viruses such as HBV and/or HIV. In one embodiment, the present invention provides compositions having the formula (I) and their use in treating viral infections: or a pharmaceutically acceptable salt, ester, stereoisomer, tautomers, solvate, prodrug, or combination thereof.
    Type: Application
    Filed: August 11, 2015
    Publication date: February 11, 2016
    Inventors: Radhakrishnan P. Iyer, Seetharamaiyer Padmanabhan
  • Compositions and methods for treating viral infections
    Patent number: 9138442
    Abstract: The present invention provides compositions methods for treating susceptible viral infections, especially hepatitis C viral (HCV) infections as well as co infections of HCV with other viruses such as HBV and/or HIV. In one embodiment, the present invention provides compositions having the formula (I) and their use in treating viral infections: or a pharmaceutically acceptable salt, ester, stereoisomer, tautomers, solvate, prodrug, or combination thereof.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: September 22, 2015
    Assignee: SPRING BANK PHARMACEUTICALS, INC.
    Inventors: Radhakrishnan P. Iyer, Seetharamaiyer Padmanabhan