Abstract: T cell receptor (TCR) diversity of a subject, including TCR diversity in CD8+ T cell subsets, is used as a predictive indicator of responsiveness of the subject to cancer immunotherapy prior to initiation of the immunotherapy. Exemplified immunotherapy comprises administering an immune checkpoint inhibitor to a subject, wherein a TCR diversity value in CD8+ T cell subsets from the subject, such as CD8+ T cell subpopulations defined by differential cell surface marker expression, is higher than a reference value.

Abstract: A method for producing a carbamic acid salt, including contacting a carbon dioxide-containing mixed gas having a partial pressure of carbon dioxide of 0.001 atm or more and less than 1 atm with an amino group-containing organic compound in the presence of a base in at least one organic solvent selected from the group consisting of an organic solvent having 2 or more and 8 or less carbon atoms, and a method for producing a carbamic acid ester or a urea derivative using the carbamic acid salt.

Abstract: Provided is a modified elastomer composition comprising components (A), (B?), and (D), wherein components (A), (B?) and (D) are grafted with component (E), component (A) comprises an ethylene-?-olefin-non-conjugated diene copolymer rubber, component (B?) comprises an ethylene-?-olefin copolymer rubber whose melting end peak temperature measured using a differential scanning calorimeter (DSC) is 90° C. or higher, component (D) comprises an unsaturated silane compound, and component (E) comprises a peroxide.

Abstract: According to one embodiment, a semiconductor device includes a memory controller and a memory device. The memory device stores firmware comprising a first portion and a second portion that is loaded after the first portion has been loaded at startup. The memory device also stores a stored authentication value that is based on the first portion of the firmware. The memory controller is configured to generate a authentication value from the first portion once the first portion has been loaded at startup.

Abstract: An object of the present invention is to provide a novel therapeutic strategy for erectile dysfunction. Disclosed is a therapeutic agent for erectile dysfunction, including a filtrate obtained by filtering a disrupted solution of adipose tissue-derived stem cells or bone marrow-derived stem cells.

Abstract: Provided is a modified elastomer composition containing components (A) to (D) and grafted with component (E). The content of component (A) is preferably 5 to 70 parts by mass based on 100 parts by mass of the total of component (A) and component (B), and the content of component (B) is preferably 95 to 30 parts by mass based on 100 parts by mass of the total of component (A) and component (B). The content of component (C) is preferably 1 to 200 parts by mass based on 100 parts by mass of the total of component (A) and component (B), and the content of component (D) is preferably 0.01 to 3 parts by mass based on 100 parts by mass of the total of component (A) and component (B).

Abstract: The present invention provides a technique for predicting an effective patient prior to starting cancer immunotherapy. The present invention provides a method of using T cell receptor (TCR) diversity of a subject as an indicator of responsiveness of the subject to cancer immunotherapy. The present invention also provides a composition for treating cancer in a subject with high TCR diversity of T cells, comprising an immune checkpoint inhibitor. The present invention is also directed to a companion medicament using such TCR diversity.

Abstract: An information communications system (100) for a vehicle includes an on-vehicle information device (10). The on-vehicle information device (10) includes: an information collection unit (11) which collects vehicle information from an on-vehicle device (41, 42, 43, 44), communication interfaces (14A, 14B) connected to mobile terminals (20) having a communication function and being brought inside the vehicle, and a control unit (12) which transfers the vehicle information collected by the information collection unit (11) to any one of the mobile terminals (20) via any one of the communication interfaces (14A, 14B). If one of the mobile terminals (20) currently selected as a destination of the vehicle information satisfies a predetermined condition, the control unit (12) switches the destination of the vehicle information to a different mobile terminal (20). The mobile terminal (20) which received the vehicle information transfers the vehicle information thus received to a center device (30).

Abstract: An information communications system (100) for a vehicle includes an on-vehicle information device (10). The on-vehicle information device (10) includes: an information collection unit (11) which collects vehicle information from an on-vehicle device (41, 42, 43, 44), communication interfaces (14A, 14B) connected to mobile terminals (20) having a communication function and being brought inside the vehicle, and a control unit (12) which transfers the vehicle information collected by the information collection unit (11) to any one of the mobile terminals (20) via any one of the communication interfaces (14A, 14B). If one of the mobile terminals (20) currently selected as a destination of the vehicle information satisfies a predetermined condition, the control unit (12) switches the destination of the vehicle information to a different mobile terminal (20). The mobile terminal (20) which received the vehicle information transfers the vehicle information thus received to a center device (30).

Abstract: A driving operation support device for a vehicle is provided herein. One exemplary driving operation support device includes a road sensor for acquiring information regarding a section of road ahead of a vehicle over which the vehicle is traveling. The driving operation support device may also include a controller for determining whether the section of road is passable for the vehicle based on the information acquired by the road sensor. The driving operation support device may further include a display provided between the section of road and a driver of the vehicle. The controller may display a guidance element on the display at a position overlapped with the section of the road as seen from the perspective of the driver, such that the guidance element indicates whether the road is passable based on the determination of the controller.

Abstract: A driving operation support device for a vehicle is provided herein. One exemplary driving operation support device includes a road sensor for acquiring information regarding a section of road ahead of a vehicle over which the vehicle is traveling. The driving operation support device may also include a controller for determining whether the section of road is passable for the vehicle based on the information acquired by the road sensor. The driving operation support device may further include a display provided between the section of road and a driver of the vehicle. The controller may display a guidance element on the display at a position overlapped with the section of the road as seen from the perspective of the driver, such that the guidance element indicates whether the road is passable based on the determination of the controller.

Abstract: Disclosed is a BSD system for vehicle provided with a blind spot detection module which includes obstacle in blind spot detection unit for detecting an obstacle existing in a blind spot around the rear side of a self vehicle and an obstacle indicator disposed on a side mirror of the self vehicle and adapted to display at least one of information for the existence of an obstacle in the blind spot, for a distance between the obstacle and the self vehicle, and for a relative speed of the obstacle to the self vehicle, the blind-spot detection system for vehicle. This system is provided with a unit for detecting that the blind spot detection module is in an abnormal operation state and a unit disposed on the side mirror having the obstacle indicator and adapted to visually indicate an abnormality of the blind spot detection module detected by the abnormality detection unit.

Abstract: According to a first aspect, there is provided a container with an electronic tag that can efficiently manage information on many containers, and is excellent in heat resistance or others, simple in structure and easy in manufacturing, wherein a bottom of a glass container body and the electronic tag are protected against mechanical impacts. According to a second aspect, there are provided a container with an electronic tag that can manage information on a product in the container and so forth without spoiling the appearance of the container accommodating the product and an RFID system using the container. In the first aspect, the container with the electronic tag includes a glass container body, a glass bottom cover member attached to a bottom of the glass container body so as to cover the bottom, and an electronic tag placed between the glass container body and the glass bottom cover member.

Abstract: Disclosed is a BSD system for vehicle provided with a blind spot detection module which includes obstacle in blind spot detection means for detecting an obstacle existing in a blind spot around the rear side of a self vehicle and an obstacle indicator disposed on a side mirror of the self vehicle and adapted to display at least one of information for the existence of an obstacle in the blind spot, for a distance between the obstacle and the self vehicle, and for a relative speed of the obstacle to the self vehicle, the blind-spot detection system for vehicle. This system is provided with means for detecting that the blind spot detection module is in an abnormal operation state and means disposed on the side mirror having the obstacle indicator and adapted to visually indicate an abnormality of the blind spot detection module detected by the abnormality detection means.

Abstract: A teletext data separation apparatus has a slice level generating circuit including a slice timing control circuit, a control register, an adder and a divider. The slice timing control circuit generates a timing signal for sampling. The control register carries out ON/OFF control of the slice timing control circuit. The control register sets by its register value the number of the sampling points of the adder and divider. By varying the register value in response to the reception state, the number of the sampling points can be increased from the specified 16 points, for example. This makes it possible for teletext data separation apparatus to generate an appropriate slice level that enables the teletext data to be separated reliably even in conditions where noise or distortion occurs in the video signal because of the effect of a weak electric field or ghost.

Abstract: A method for fabricating a glass substrate for information recording media. A uniform texture can be formed in a major surface of the glass substrate without degrading the smoothness of the major surface. The method comprises a step of forming a texture in a major surface of a disk-shaped glass substrate by lapping the major surface with a lapping member while supplying an abrasive material onto the major surface. In the step, the glass substrate is reciprocated in a radial direction while rotating the glass substrate around its center at a predetermine rotational speed. The rotational speed, the reciprocating speed, and the reciprocation stroke are so determined that the locus of every particle of the abrasive material crosses itself at least at three points.

Abstract: An on-screen display unit includes OSD (on-screen display) RAMs each for storing data on one of OSD blocks to be subjected to OSD; a memory bus for transferring data to be stored to the OSD RAMs from a CPU; and an OSD local bus for transferring the data stored in the OSD RAMs to make the OSD. The OSD RAMs are supplied with the data to be stored through the control of switches alternately, and transfer the stored data to the OSD local bus 12 alternately. The on-screen display unit can cope with a high frequency OSD clock signal, and carry out the OSD normally.

Abstract: A teletext data separation apparatus has a slice level generating circuit including a slice timing control circuit, a control register, an adder and a divider. The slice timing control circuit generates a timing signal for sampling. The control register carries out ON/OFF control of the slice timing control circuit. The control register sets by its register value the number of the sampling points of the adder and divider. By varying the register value in response to the reception state, the number of the sampling points can be increased from the specified 16 points, for example. This makes it possible for teletext data separation apparatus to generate an appropriate slice level that enables the teletext data to be separated reliably even in conditions where noise or distortion occurs in the video signal because of the effect of a weak electric field or ghost.

Abstract: In a variable intake apparatus for a multi-cylinder internal combustion engine, each cylinder is allowed to communicate with each other through air intake passageways including at least a pair of air intake passageway portions. Further, an air intake control valve integrally provided with a pair of valve bodies is disposed at an opening which is formed at a partition wall. The partition wall is formed between the intake air collecting chamber and the air intake passageway. Further more, the air intake control valve is actuated according to engine speeds of the internal combustion engine such that the air intake passageway portion is opened and closed by one of the valve bodies whereas the opening in the partition wall is opened and closed by the other of the valve bodies.

Abstract: In a variable intake apparatus for a multi-cylinder internal combustion engine, each cylinder are allowed to communicate with each other through air intake passageways including at least a pair of air intake passageway portions. Further, an air intake control valve integrally provided with a pair of valve bodies is disposed at an opening which is formed at a partition wall. The partition wall is formed-between the intake air collecting chamber and the air intake passageway. Further more, the air intake control valve is actuated according to engine speeds of the internal combustion engine such that the air intake passageway portion is opened and closed by the valve body whereas the opening in the partition wall is opened and closed by the other valve body.