Abstract: Non-conventional yeasts are disclosed herein comprising at least one RNA-guided endonuclease (RGEN) comprising at least one RNA component that does not have a 5?-cap. This uncapped RNA component comprises a sequence complementary to a target site sequence in a chromosome or episome in the yeast. The RGEN can bind to, and optionally cleave, one or both DNA strands at the target site sequence. An example of an RGEN herein is a complex of a Cas9 protein with a guide RNA. A ribozyme is used in certain embodiments to provide an RNA component lacking a 5?-cap. Further disclosed are methods of genetic targeting in non-conventional yeast.

Abstract: A composition is disclosed that comprises at least one protein component of an RNA-guided endonuclease (RGEN) and at least one cell-penetrating peptide (CPP), wherein the RGEN protein component and CPP are covalently or non-covalently linked to each other in an RGEN protein-CPP complex. The RGEN protein-CPP complex can traverse (i) a cell membrane, or (ii) a cell wall and cell membrane, of a cell. The RGEN protein component of an RGEN protein-CPP complex in certain embodiments can be associated with a suitable RNA component to provide an RGEN capable of specific DNA targeting. Further disclosed are compositions comprising at least one protein component of a guide polynucleotide/Cas endonuclease complex and at least one CPP, as well as methods of delivering RGEN proteins into microbial cells, as well as methods of targeting DNA with RGENs.

Abstract: The present disclosure relates to a sensor network, Machine Type Communication (MTC), Machine-to-Machine (M2M) communication, and technology for Internet of Things (IoT). The present disclosure may be applied to intelligent services based on the above technologies, such as smart home, smart building, smart city, smart car, connected car, health care, digital education, smart retail, security and safety services. A method and apparatus for processing a signal in a mobile device are provided. The method includes classifying signals transmitted and received between devices according to at least two predetermined rates, and transmitting and receiving the classified signals in connection lines supporting the at least two rates, respectively.

Abstract: Recombinant microbial cells comprising an engineered LCDA production pathway that comprises at least one up-regulated long-chain acyl-CoA synthetase (ACoS) are disclosed. These recombinant microbial cells are capable of producing one or more long-chain dicarboxylic acid (LCDA) products from a long-chain fatty acid-comprising substrate. Methods of using recombinant microbial cells to produce LCDAs are also disclosed.

Abstract: A reflector device configured for vehicle lamps which is configured for causing light to exit along a plurality of paths using a single light source and a single reflector, may include a fluid, the position of which is changed in a response to magnetism, is provided at the reflector such that the exit path of light is changed depending on the flow of the fluid, whereby it is possible to realize a lamp having various functions.

Abstract: A composition is disclosed that comprises at least one protein component of an RNA-guided endonuclease (RGEN) and at least one cell-penetrating peptide (CPP), wherein the RGEN protein component and CPP are covalently or non-covalently linked to each other in an RGEN protein-CPP complex. The RGEN protein-CPP complex can traverse (i) a cell membrane, or (ii) a cell wall and cell membrane, of a cell. The RGEN protein component of an RGEN protein-CPP complex in certain embodiments can be associated with a suitable RNA component to provide an RGEN capable of specific DNA targeting. Further disclosed are compositions comprising at least one protein component of a guide polynucleotide/Cas endonuclease complex and at least one CPP, as well as methods of delivering RGEN proteins into microbial cells, as well as methods of targeting DNA with RGENs.

Abstract: A light source device using a polarity of a material may include a transparent frame forming an inner space accommodating a nonpolarity material and a polarity material; a light source portion irradiating light through the nonpolarity material or the polar material accommodated in the transparent frame; and an electromagnet configured to switch respective positions of the nonpolarity material and the polar material by a magnetic force generated as a current is applied from outside of the light source device.

Abstract: Non-conventional yeasts are disclosed herein comprising at least one RNA-guided endonuclease (RGEN) comprising at least one RNA component that does not have a 5?-cap. This uncapped RNA component comprises a sequence complementary to a target site sequence in a chromosome or episome in the yeast. The RGEN can bind to, and optionally cleave, one or both DNA strands at the target site sequence. An example of an RGEN herein is a complex of a Cas9 protein with a guide RNA. A ribozyme is used in certain embodiments to provide an RNA component lacking a 5?-cap. Further disclosed are methods of genetic targeting in non-conventional yeast.

Abstract: A content output system is provided. The content output system includes a display apparatus configured to display a user interface (UI) for guiding a user input for setting a speaker corresponding to each of a plurality of channels according to a predetermined event and a plurality of speaker apparatuses configured to, in response to a user input corresponding to the user input guide being received, transmit a first signal corresponding to the user input to the display apparatus.

Abstract: A backlight unit and a display device including the same are provided. The backlight unit includes a light source; a mold frame configured to accommodate the light source and having a window frame shape with an opening therein; and a supporting member disposed on the mold frame and comprising an optical pattern, wherein the mold frame comprises a first sidewall, and an inclined surface protruding obliquely downward and inward from an inner side surface of the first sidewall, and wherein the supporting member is disposed on the inclined surface of the mold frame.

Abstract: Compositions and methods are provided for editing nucleotides and/or altering target sites in the genome of a cell. The methods and compositions employ a recombinant DNA construct comprising a tRNA promoter operably linked to a polynucleotide encoding a single guide RNA, wherein said recombinant DNA construct does not comprise a nucleotide sequence encoding a ribozyme, wherein said guide RNA is capable of forming a guide RNA/Cas endonuclease complex, wherein said complex can bind to and cleave a target site sequence in the genome of a cell such as a microbial cell.

Abstract: The present disclosure relates to a pre-5th-generation (5G) or 5G communication system to be provided for supporting higher data rates beyond 4th-generation (4G) communication system such as long term evolution (LTE). An electronic device is provided in a wireless communication system. The device comprises a plurality of antenna sets; a plurality of antenna elements configuring the plurality of antenna sets; an RF transceiver including a plurality of switches for selecting the plurality of antenna elements and a plurality of phase shifters for shifting the phase of a signal transmitted/received through the plurality of antenna elements; and a control unit for determining a beam forming direction and the phase of the signal by simultaneously controlling the plurality of switches and the plurality of phase shifters according to a beambook.

Abstract: A backlight unit includes a light source, a mold frame which accommodates the light source includes at least a first sidewall and an inclined surface protruding and sloping downward from an inner side surface of the first sidewall. A second sidewall may extend from the inclined surface in which the second sidewall is arranged substantially parallel to the first sidewall and has a space therebetween. The support member is disposed on the inclined surface of the mold frame. An optical plate may be disposed on an upper surface of the support member, and the optical plate and the inclined surface of the mold frame define an optical path in a space there between.

Abstract: A lamp device for a vehicle is provided. The lamp device includes a light source, a lamp housing that accommodates the light source thereon. A lens is coupled to the lamp housing to allow light emitted from the light source to penetrate the lens and a bezel is coupled to the lamp housing and is disposed between the lens and the light source. In particular, the bezel has a surface structure formed on a rear surface thereof and is configured to reflect irradiated light. The bezel is formed in a color that is complementary to a color of the lens.

Abstract: A light source device using a polarity of a material may include a transparent frame forming an inner space accommodating a nonpolarity material and a polarity material; a light source portion irradiating light through the nonpolarity material or the polar material accommodated in the transparent frame; and an electromagnet configured to switch respective positions of the nonpolarity material and the polar material by a magnetic force generated as a current is applied from outside of the light source device.

Abstract: Recombinant microbial cells comprising an engineered LCDA production pathway that comprises at least one up-regulated long-chain acyl-CoA synthetase (ACoS) are disclosed. These recombinant microbial cells are capable of producing one or more long-chain dicarboxylic acid (LCDA) products from a long-chain fatty acid-comprising substrate. Methods of using recombinant microbial cells to produce LCDAs are also disclosed.

Abstract: A composition is disclosed that comprises at least one protein component of an RNA-guided endonuclease (RGEN) and at least one cell-penetrating peptide (CPP), wherein the RGEN protein component and CPP are covalently or non-covalently linked to each other in an RGEN protein-CPP complex. The RGEN protein-CPP complex can traverse (i) a cell membrane, or (ii) a cell wall and cell membrane, of a cell. The RGEN protein component of an RGEN protein-CPP complex in certain embodiments can be associated with a suitable RNA component to provide an RGEN capable of specific DNA targeting. Further disclosed are compositions comprising at least one protein component of a guide polynucleotide/Cas endonuclease complex and at least one CPP, as well as methods of delivering RGEN proteins into microbial cells, as well as methods of targeting DNA with RGENs.

Abstract: A composition is disclosed that comprises at least one protein component of an RNA-guided endonuclease (RGEN) and at least one cell-penetrating peptide (CPP), wherein the RGEN protein component and CPP are covalently or non-covalently linked to each other in an RGEN protein-CPP complex. The RGEN protein-CPP complex can traverse (i) a cell membrane, or (ii) a cell wall and cell membrane, of a cell. The RGEN protein component of an RGEN protein-CPP complex in certain embodiments can be associated with a suitable RNA component to provide an RGEN capable of specific DNA targeting. Further disclosed are compositions comprising at least one protein component of a guide polynucleotide/Cas endonuclease complex and at least one CPP, as well as methods of delivering RGEN proteins into microbial cells, as well as methods of targeting DNA with RGENs.

Abstract: Disclosed are a adhesive composition and a method of surface-treating a molded article using the same. In particular, the adhesive composition may be eco-friendly because smell and VOC generation from the organic solvent are reduced by adding a water-dilutable polyurethane resin having a hydroxyl group to a waterborne polyurethane resin, thereby improving properties such as elastic recoverability and scratch resistance while satisfying conventional properties.

Abstract: A content output system is provided. The content output system includes a display apparatus configured to display a user interface (UI) for guiding a user input for setting a speaker corresponding to each of a plurality of channels according to a predetermined event and a plurality of speaker apparatuses configured to, in response to a user input corresponding to the user input guide being received, transmit a first signal corresponding to the user input to the display apparatus.