Patents by Inventor Seymour Bernstein

Seymour Bernstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclic substituted-amino-pyrazolines
    Patent number: 4622401
    Abstract: This invention relates to novel 3-amino-1-heteroaryl-2-pyrazolines and their C.sub.4 and C.sub.5 analogs, useful for meliorating the inflammation and/or the progressive joint deterioration characteristic of arthritic disease, preventing the onset of asthmatic symptoms and allergic diseases, or as analgesic, antibacterial or antifungal agents.
    Type: Grant
    Filed: September 19, 1984
    Date of Patent: November 11, 1986
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Joseph P. Joseph, Seymour Bernstein
  • Polyanionic benzene ureas
    Patent number: 4608205
    Abstract: Polyanionic benzene ureas and salts thereof useful as complement inhibitors.
    Type: Grant
    Filed: September 24, 1984
    Date of Patent: August 26, 1986
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Multisulfonated naphthalene ureas useful as complement inhibitors
    Patent number: 4599203
    Abstract: Multisulfonated naphthalene ureas, useful as complement inhibitors.
    Type: Grant
    Filed: March 28, 1984
    Date of Patent: July 8, 1986
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Oxalylamides useful as dental antiplaque agents and inhibitors of connective tissue destruction
    Patent number: 4599204
    Abstract: This invention concerns novel compounds useful in compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals and as inhibitors of connective tissue destruction. The compounds of this invention comprise certain [oxalylbis(iminophenylenecarbonylimino)]bis[hydroxynaphthalenesulfonic acids] and salts thereof which may be combined with pharmaceutically acceptable carriers or diluents to be administered in the form of conventional pharmaceutical compositions.
    Type: Grant
    Filed: March 11, 1985
    Date of Patent: July 8, 1986
    Assignee: American Cyanamid Company
    Inventors: John F. Poletto, Seymour Bernstein
  • Method of inhibiting the complement system by administering multisulfonated naphthalene ureas
    Patent number: 4591604
    Abstract: A method of inhibiting the complement system using multisulfonated naphthalene ureas.
    Type: Grant
    Filed: August 27, 1984
    Date of Patent: May 27, 1986
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Substituted phenyl-1-thio(poly-O-sulfo)-.alpha.(or .beta.)-D-glucopyranosides
    Patent number: 4515782
    Abstract: Cation salts of substituted phenyl-1-thio(poly-O-sulfo)-.alpha.(or .beta.)-D-glucopyranoside, useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and end products.
    Type: Grant
    Filed: August 29, 1983
    Date of Patent: May 7, 1985
    Assignee: American Cyanamid Company
    Inventors: Robert E. Schaub, Thomas G. Miner, Seymour Bernstein
  • Poly-cation salt of 4-O-polyhexaose-thio-arylene sulfates
    Patent number: 4470976
    Abstract: Poly-cation salts of 4-O-polyhexaose-thio-arylene sulfate derivatives, useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and products.
    Type: Grant
    Filed: August 29, 1983
    Date of Patent: September 11, 1984
    Assignee: American Cyanamid Company
    Inventors: Thomas G. Miner, Robert E. Schaub, Seymour Bernstein
  • Poly-cation salts of 4-O-poly-hexaose-thio-alkylene sulfate derivatives and method of use
    Patent number: 4468385
    Abstract: Poly-cation salts of 4-O-polyhexaose-thio-alkylene sulfate derivatives, useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and products.
    Type: Grant
    Filed: August 29, 1983
    Date of Patent: August 28, 1984
    Assignee: American Cyanamid Company
    Inventors: Francis M. Callahan, Thomas G. Miner, Seymour Bernstein
  • Method of modulating the complement system by administering bis-[.beta.-D-glucopyranosyl-1-thio (or sulfinyl or sulfonyl)]-aryline sulfate derivatives and the cation salts thereof
    Patent number: 4459293
    Abstract: Bis-[.beta.-D-glucopyranosyl-1-thio (or sulfinyl or sulfonyl)]-arylene sulfate derivatives, the cation salts thereof, useful as modulators of the complement system, the intermediates thereof and the process for the preparation of such intermediates and end products.
    Type: Grant
    Filed: April 28, 1983
    Date of Patent: July 10, 1984
    Assignee: American Cyanamid Company
    Inventors: Miner Thomas G., Seymour Bernstein
  • Therapeutically active 3-amino-1-halogenated phenyl-2-pyrazolines and their C4 and C5 analogs
    Patent number: 4451479
    Abstract: A method of meliorating the inflammation and/or the progressive joint deterioration characteristic of arthritic disease, preventing the onset of asthmatic symptoms and allergic diseases, treating pain or treating bacterial and fungal infections in mammals using 3-amino-1-halogenated phenyl-2-pyrazolines and their C4 and C5 analogs.
    Type: Grant
    Filed: October 4, 1982
    Date of Patent: May 29, 1984
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Joseph P. Joseph, Seymour Bernstein
  • Therapeutically active 3-substituted amino-1-phenyl and substituted phenyl-2-pyrazolines
    Patent number: 4448973
    Abstract: 3-substituted amino-1-phenyl-2-pyrazolines and 3-substituted amino-1-substituted phenyl-2-pyrazolines and their C.sub.4 and C.sub.5 analogs, useful for meliorating the inflammation and/or the progressive joint deterioration characteristic of arthritic disease, preventing the onset of asthmatic symptoms and allergic diseases, or as analgesic, antibacterial or antifungal agents.
    Type: Grant
    Filed: May 10, 1982
    Date of Patent: May 15, 1984
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Joseph P. Joseph, Seymour Bernstein
  • Poly-cation salts of bis(or tris)[4-O-monohexose-oxy]-arylene sulfate derivatives
    Patent number: 4440758
    Abstract: Poly-cation salts of bis(or tris)[4-O-monohexose-oxy]-arylene sulfate derivatives useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and products.
    Type: Grant
    Filed: October 25, 1982
    Date of Patent: April 3, 1984
    Assignee: American Cyanamid Company
    Inventors: Janis Upeslacis, Robert E. Schaub, Seymour Bernstein
  • Poly-cation salts of bis (or tris) 4-O-polyhexose-thio-arylene sulfate derivatives
    Patent number: 4435387
    Abstract: Poly-cation salts of bis (or tris) 4-O-polyhexose-thio-arylene sulfate derivatives, useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and end products.
    Type: Grant
    Filed: October 25, 1982
    Date of Patent: March 6, 1984
    Assignee: American Cyanamid Company
    Inventors: Robert E. Schaub, Janis Upeslacis, Seymour Bernstein
  • Therapeutically active 3-amino-1-phenyl(and substituted phenyl)-2-pyrazolines
    Patent number: 4432991
    Abstract: This disclosure describes certain 3-amino-1-phenyl-2-pyrazolines and 3-amino-1-substituted phenyl-2-pyrazolines and their C4 and C5 analogs useful for meliorating the inflammation and/or the progressive joint deterioration characteristic of arthritic disease, preventing the onset of asthmatic symptoms and allergic diseases, or as analgesic, antibacterial or antifungal agents.
    Type: Grant
    Filed: November 1, 1982
    Date of Patent: February 21, 1984
    Assignee: American Cyanamid Company
    Inventors: John P. Dusza, Joseph P. Joseph, Seymour Bernstein
  • Bis(4-O-polyhexaose-thio)-phenyl ureas and method of use
    Patent number: 4431636
    Abstract: Poly-cation salts of bis (4-O-polyhexaose-thio)-phenyl urea sulfate derivatives, useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and end products.
    Type: Grant
    Filed: May 24, 1982
    Date of Patent: February 14, 1984
    Assignee: American Cyanamid Company
    Inventors: Robert E. Schaub, Janis Upeslacis, Seymour Bernstein
  • Poly-cation salts of bis(or tris)[4-0-monohexose-thio]-arylene sulfate derivatives
    Patent number: 4431638
    Abstract: Poly-cation salts of bis(or tris)[4-O-monohexose-thio]-arylene sulfate derivatives useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and end products.
    Type: Grant
    Filed: October 25, 1982
    Date of Patent: February 14, 1984
    Assignee: American Cyanamid Company
    Inventors: Robert E. Schaub, Janis Upeslacis, Seymour Bernstein
  • Polycation salts of bis (or tris) [4-O-polyhexose-oxy]-arylene sulfate derivatives
    Patent number: 4431637
    Abstract: Poly-cation salts of bis (or tris) [4-O-polyhexose-oxy]-arylene sulfate derivatives useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and end products.
    Type: Grant
    Filed: October 25, 1982
    Date of Patent: February 14, 1984
    Assignee: American Cyanamid Company
    Inventors: Janis Upeslacis, Robert E. Schaub, Seymour Bernstein
  • Rutin poly(H-)sulfate salts and related compounds
    Patent number: 4414207
    Abstract: Rutin poly(H-)sulfate and salts thereof useful as complement inhibitors.
    Type: Grant
    Filed: February 22, 1982
    Date of Patent: November 8, 1983
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, Seymour Bernstein
  • Modulators of the complement system
    Patent number: 4407796
    Abstract: Poly-cation salts of bis-(or tris-) [polyhexaose-thio (or sulfinyl, or sulfonyl)]-arylene sulfate derivatives, useful as modulators of the complement system, the intermediates thereof and the process of making such intermediates and end products.
    Type: Grant
    Filed: December 28, 1981
    Date of Patent: October 4, 1983
    Assignee: American Cyanamid Company
    Inventors: Thomas G. Miner, Seymour Bernstein
  • Dental antiplaque agents and inhibitors of connective tissue destruction
    Patent number: H83
    Abstract: This invention concerns novel compounds useful in compositions and methods for preventing the attachment of dental plaque to the surfaces of the teeth of mammals and as inhibitors of connective tissue destruction. The compounds of this invention comprise certain [ureylenebis-(phenylenesulfonylimino)]bis[hydroxynaphthalenesulfonic acids] and salts thereof which may be combined with pharmaceutically acceptable carriers or diluents to be administered in the form of conventional pharmaceutical compositions.
    Type: Grant
    Filed: March 11, 1985
    Date of Patent: July 1, 1986
    Assignee: American Cyanamid Company
    Inventors: John F. Poletto, Seymour Bernstein