Patents by Inventor Seymour Bernstein

Seymour Bernstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Ureylene phenylene anionic naphthalenesulfonic acids
    Patent number: 4229370
    Abstract: Novel ureylenebis[substituted-phenylenecarbonyl(and sulfonyl)imino-subsituted-phenylenesulfonylimino-naphthalenetrisulfonic acid hexaalkali metal salts], useful as inhibitors of the complement system of warm-blooded animals, the amino-substituted phenylenecarbonyl(and sulfonyl)imino-substituted-phenylenesulfonylimino-na phthalenetrisulfonic acid, trialkali metal salts, which are new intermediates for the preparation of the active ureylenes, and the process for their preparation.
    Type: Grant
    Filed: March 5, 1979
    Date of Patent: October 21, 1980
    Assignee: American Cyanamid Company
    Inventors: Gerald J. Siuta, Ransom B. Conrow, John F. Poletto, Seymour Bernstein
  • Ureylene phenylene anionic naphthalenesulfonic acids
    Patent number: 4229372
    Abstract: Novel ureylenebis-[substituted-phenylenecarbonylimino-substituted-phenylenesulfo nylimino]naphthalenetrisulfonic acid alkali metal salts], useful as inhibitors of the complement system of warm-blooded animals, the amino-substituted phenylenecarbonyl imino, substituted-phenylenesulfonylimino-naphthalenetrisulfonic acid, alkali metal salts, which are new intermediates for the preparation of the active ureylenes, and the process for their preparation.
    Type: Grant
    Filed: March 5, 1979
    Date of Patent: October 21, 1980
    Assignee: American Cyanamid Company
    Inventors: Gerald J. Siuta, Ransom B. Conrow, John F. Poletto, Seymour Bernstein
  • Ureylene naphthalene sulfonic acid intermediates
    Patent number: 4229371
    Abstract: Ureylenebis substituted phenylenecarbonylimino symmetrical phenenylbiscarbonylimino dinaphthalenepoly-sulfonic acid salts, and nitro and amino substituted benzamido phenylenedicarbonyl dinaphthalenepoly-sulfonic acid salts that are new intermediates for the preparation of the active ureides, which have complement inhibiting activity.
    Type: Grant
    Filed: October 13, 1978
    Date of Patent: October 21, 1980
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Ureylenebis(anionic substituted phenylene carbonyl)imino naphthalene sulfonic acids and naphthalene carboxylic acids and their salts
    Patent number: 4229584
    Abstract: Ureylenebis(anionic substituted phenylene carbonyl)imino naphthalene sulfonic acids and naphthalene carboxylic acids and their salts, which are useful as inhibitors of the complement system of warm-blooded animals. Naphthyl sulfobenzamido salts, which are new intermediates for the preparation of the active ureylenes, and the process for their preparation.
    Type: Grant
    Filed: October 2, 1978
    Date of Patent: October 21, 1980
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Substituted O-.alpha.-D and O-.beta.-D-multi-galactopyranosyl and glucopyranosyl 1.fwdarw.4 and 1.fwdarw.6 galactopyranosyl 1.fwdarw.6 .alpha.-D-glucopyranoses
    Patent number: 4221907
    Abstract: O-.alpha.-D (and O-.beta.-D) multi-galactopyranosyl (and glucopyranosyl) 1.fwdarw.4 (and 1.fwdarw.6) galactopyranosyl 1.fwdarw.6-.alpha.-D-glucopyranose sulfate salts which are useful as complement inhibitors.
    Type: Grant
    Filed: July 9, 1979
    Date of Patent: September 9, 1980
    Assignee: American Cyanamid Company
    Inventors: Vijay G. Nair, Joseph P. Joseph, Seymour Bernstein
  • Ureylene naphthalene sulfonic acids
    Patent number: 4218395
    Abstract: Ureylenebis-symmetrical-phenenylbiscarbonylimino-substituted phenylenecarbonylimino-tetranaphthalenepolysulfonic acid benzoic acid salts, and nitro- and amino-substituted phenylenebiscarbonylimino-substituted benzamido-phenylenedicarbonyl-dinaphthalenepolysulfonic acid benzoic acid salts which are intermediates for the preparation of the active ureides which have complement inhibiting activity.
    Type: Grant
    Filed: August 28, 1978
    Date of Patent: August 19, 1980
    Assignee: American Cyanamid Company
    Inventors: John F. Poletto, Seymour Bernstein
  • Amine precursors to ureide inhibitors of connective tissue destruction
    Patent number: 4216165
    Abstract: Certain amino-benzamido-naphthalenemonosulfonic acids and salts thereof useful in the preparation of the corresponding ureides useful as inhibitors of connective tissue destruction.
    Type: Grant
    Filed: December 20, 1978
    Date of Patent: August 5, 1980
    Assignee: American Cyanamid Company
    Inventor: Seymour Bernstein
  • Nitro precursors to amine precursors to ureide inhibitors of connective tissue destruction
    Patent number: 4216166
    Abstract: Certain nitro-benzamido-naphthalenemonosulfonic acids and salts thereof useful in the preparation of the corresponding amino precursors to the final product ureides which are useful as inhibitors of connective tissue destruction.
    Type: Grant
    Filed: December 20, 1978
    Date of Patent: August 5, 1980
    Assignee: American Cyanamid Company
    Inventor: Seymour Bernstein
  • Ureide inhibitors of connective tissue destruction
    Patent number: 4216164
    Abstract: Certain ureides of substituted naphtholmonosulfonic acids and salts useful as inhibitors of connective tissue destruction.
    Type: Grant
    Filed: December 20, 1978
    Date of Patent: August 5, 1980
    Assignee: American Cyanamid Company
    Inventor: Seymour Bernstein
  • s-Phenenyltris(sulfonylimino)tri-benzene mono-and di-sulfonic acids and salts
    Patent number: 4208346
    Abstract: s-Phenenyltris(sulfonylimino)tri-benzene mono-and di-sulfonic acids and their salts which are useful as complement inhibitors.
    Type: Grant
    Filed: December 26, 1978
    Date of Patent: June 17, 1980
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Ureylene phenylene anionic naphthalenesulfonic acids
    Patent number: 4185032
    Abstract: Novel ureylenebis-[substituted-phenylenecarbonylimino-substituted-phenylenecarbo nylimino-naphthalenetrisulfonic acid, alkali metal salts], useful as inhibitors of the complement system of warm-blooded animals, the amino-substituted phenylenecarbonylimino, substituted-phenylenecarbonylimino-naphthalenetrisulfonic acid, alkali metal salts, which are new intermediates for the preparation of the active ureylenes, and the process for their preparation.
    Type: Grant
    Filed: July 11, 1978
    Date of Patent: January 22, 1980
    Assignee: American Cyanamid Company
    Inventors: Gerald J. Siuta, Ransom B. Conrow, John F. Poletto, Seymour Bernstein
  • Ureylene phenylene anionic naphthalenesulfonic acids
    Patent number: 4185033
    Abstract: Novel ureylenebis-[substituted-phenylenecarbonylimino-substituted-phenylenecarbo nylimino-naphthalenetrisulfonic acid, alkali metal salts], useful as inhibitors of the complement system of warm-blooded animals, the amino-substituted phenylenecarbonylimino, substituted-phenylenecarbonylimino-naphthalenetrisulfonic acid, alkali metal salts, which are new intermediates for the preparation of the active ureylenes, and the process for their preparation.
    Type: Grant
    Filed: July 11, 1978
    Date of Patent: January 22, 1980
    Assignee: American Cyanamid Company
    Inventors: Gerald J. Siuta, Ransom B. Conrow, John F. Poletto, Seymour Bernstein
  • Tri-substituted triazines
    Patent number: 4183929
    Abstract: Tri-substituted s-triazine di and triimino substituted alkyl and aryl mono and dicarboxylic acids and salts thereof useful as complement inhibitors.
    Type: Grant
    Filed: October 13, 1978
    Date of Patent: January 15, 1980
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Ureylene phenylene anionic naphthalenesulfonic acids as complement inhibitors
    Patent number: 4180587
    Abstract: A method of inhibiting the complement system in a warm-blooded animal which comprises the administration of a ureylenebis-[substituted-phenylenecarbonyl (and sulfonyl) imino-substituted-phenylene carbonylimino-naphthalenetrisulfonic acid, hexaalkali metal salt].
    Type: Grant
    Filed: July 11, 1978
    Date of Patent: December 25, 1979
    Assignee: American Cyanamid Company
    Inventors: Gerald J. Siuta, Ransom B. Conrow, John F. Poletto, Seymour Bernstein
  • Ureylenebis(anionic substituted phenylene carbonyl)imino naphthalene sulfonic acids and naphthalene carboxylic acids and their salts
    Patent number: 4177209
    Abstract: Ureylenebis(anionic substituted phenylene carbonyl)imino naphthalene sulfonic acids and naphthalene carboxylic acids and their salts, which are useful as inhibitors of the complement system of warm-blooded animals. Naphthyl sulfobenzoamido salts, which are new intermediates for the preparation of the active ureylenes, and the process for their preparation.
    Type: Grant
    Filed: October 4, 1978
    Date of Patent: December 4, 1979
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • S-Phenenyltris(sulfonylimino)tri-anionic substituted benzene carboxylic acids
    Patent number: 4172210
    Abstract: s-Phenenyltris(sulfonylimino)tri-anionic substituted benzene dicarboxylic acids and substituted alkyl amino acids and their salts, useful as complement inhibitors.
    Type: Grant
    Filed: August 28, 1978
    Date of Patent: October 23, 1979
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Substituted aromatic naphthalene sulfonamides
    Patent number: 4172089
    Abstract: Substituted benzenesulfonic acid salts and amides of naphthalenetrisulfonamides and salts thereof useful as complement inhibitors, as well as triphenyl and hexaphenyl esters of substituted benzenesulfonic acid-naphthalenetrisulfonanilides which are new intermediates for the preparation of the active naphthalenetrisulfonamides and the process for their preparation.
    Type: Grant
    Filed: July 17, 1978
    Date of Patent: October 23, 1979
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Phenenyltris (carbonylimino)multi-anionic substituted triphenyl acids and salts
    Patent number: 4159384
    Abstract: Phenenyltris(carbonylimino) multi-anionic substituted triphenyl acids and salts useful as complement inhibitors.
    Type: Grant
    Filed: September 1, 1978
    Date of Patent: June 26, 1979
    Assignee: American Cyanamid Company
    Inventors: Ransom B. Conrow, Seymour Bernstein
  • Ureylene phenylene anionic naphthalenesulfonic acids
    Patent number: 4155931
    Abstract: Novel ureylenebis-[substituted-phenylenecarbonylimino-substituted-phenylenesulfo nylimino]naphthalenetrisulfonic acid alkali metal salts], useful as inhibitors of the complement system of warm-blooded animals, the amino-substituted phenylenecarbonyl imino, substituted-phenylenesulfonylimino-naphthalenetrisulfonic acid, alkali metal salts, which are new intermediates for the preparation of the active ureylenes, and the process for their preparation.
    Type: Grant
    Filed: July 11, 1978
    Date of Patent: May 22, 1979
    Assignee: American Cyanamid Company
    Inventors: Gerald J. Siuta, Ransom B. Conrow, John F. Poletto, Seymour Bernstein
  • Ureylene phenylene anionic naphthalenesulfonic acids
    Patent number: 4155930
    Abstract: Novel ureylenebis[substituted-phenylenecarbonyl-(and sulfonyl)imino-substituted-phenylenesulfonylimino-naphthalenetrisulfonic acid hexaalkali metal salts], useful as inhibitors of the complement system of warm-blooded animals, the amino-substituted phenylenecarbonyl (and sulfonyl)imino-substituted-phenylenesulfonylimino-naphthalenetrisulfonic acid, trialkali metal salts, which are new intermediates for the preparation of the active ureylenes, and the process for their preparation.
    Type: Grant
    Filed: July 11, 1978
    Date of Patent: May 22, 1979
    Assignee: American Cyanamid Company
    Inventors: Gerald J. Siuta, Ransom B. Conrow, John F. Poletto, Seymour Bernstein