Abstract: A wiring board includes a mother board and a daughter board that are stacked, a bonding layer disposed between the mother board and the daughter board, and at least one side wiring. The mother board includes a first substrate, and a first wiring layer disposed on the first substrate and including at least one first connection pad. The daughter board is disposed on a side of the first substrate away from the first wiring layer. The daughter board includes a second substrate, and a second wiring layer disposed on the second substrate and including at least one second connection pad. The at least one side wiring is connected, via a respective end thereof, to the at least one first connection pad in one-to-one correspondence, and the at least one side wiring is connected, via respective another end thereof, to the at least one second connection pad in one-to-one correspondence.

Abstract: An image segmentation apparatus according to an embodiment includes processing circuitry configured: to calculate a variable field-of-view mathematical function capable of adaptively generating fields of view having corresponding sizes, with respect to a plurality of segmentation targets included in an image; to generate patches having corresponding sizes, with respect to the plurality of segmentation targets, by using the variable field-of-view mathematical function; and to obtain a segmentation result of the plurality of segmentation targets, by carrying out an inference on the image while using a segmentation model trained with the patches.

Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.

Abstract: An image processing method according to an embodiment includes a specifying step, an inference step, and an integration step. In the specifying step, a first portion including a region corresponding to an anatomical site of a target and a second portion including a region different from the anatomical site are specified in the image. In the inference step, by using a deep learning model, segmentation of the region corresponding to the anatomical site is performed on the first portion and segmentation of the region different from the anatomical site is performed on the second portion, or classification and detection of an image including the region corresponding to the anatomical site is performed on the first portion and classification and detection of an image including the region different from the anatomical site is performed on the second portion. In the integration step, results of the respective processes are integrated for output.

Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.

Abstract: A model training device according to an embodiment of the present disclosure includes processing circuitry. The processing circuitry is configured to obtain an initial learning model by learning a data set including medical images as learning data. The processing circuitry is configured to evaluate the initial learning model by using a global metric, so as to obtain error data sets each having an outlier from among a plurality of data sets used in the evaluation. The processing circuitry is configured to obtain a plurality of error data set groups by grouping the plurality of error data sets while using a local metric. The processing circuitry is configured to specify model training information with respect to each of the error data set groups.

Abstract: A direct chemical lysis composition includes an assay compatible buffer composition and an assay compatible surfactant. When combined with a specimen storage composition, such compositions prevent undesired modifications to nucleic acid and proteins lysed from cells in the biological sample. Assays of samples from such compositions do not require expensive and time-consuming steps such as centrifugation and prolonged high temperature processing. The direct chemical lysis composition of the present invention permits direct nucleic acid extraction from the cells in the biological sample without the need to decant off the transport media or otherwise exchange the transport media with assay compatible buffers. There is no need to combine the sample with proteinase K or another enzyme to extract nucleic acids from the cells. A method for lysing cells to obtain target nucleic acid for assay and a kit for combining the direct chemical lysis composition with a sample are also contemplated.

Abstract: A method and apparatus for generating and utilizing spreading sequence codebooks for a symbol-level sequence spreading is disclosed. In one embodiment, a method performed by a wireless communication device, comprising: receiving a first number from a wireless communication node; selecting a first spreading sequence codebook from at least one spreading sequence codebook; selecting a first spreading sequence from the first spreading sequence codebook according to the first number; and spreading data symbols according to the first spreading sequence, wherein the at least one spreading sequence codebook each comprises a plurality of spreading sequences configured based on one entry of a first sequence set after cyclic shifting operation, wherein the first sequence set before cyclic shifting operation is configured based on a second sequence set.

Abstract: The present invention discloses a method for designing a refiner plate with three-stage radial curved bars, comprising following steps of: designing a circle arc for 1st stage radial curved bars; designing a circle arc for the 2nd stage radial curved bars; designing a circle arc for 3rd stage radial curved bars; and designing a center angle for the refiner plate according to the size of the refiner plate and the manufacture requirements, to complete the design of the refiner plate. In the present invention, by the establishment of equations for the circle arcs and angles of inclination of the curved bars, it is ensured that the width of the bars will not change in the radial direction, and both the flexibility in designing a curved refiner plate and the uniformity of crushing are improved. This design method provides a theory basis and also instructions for designing multi-stage radial curved bars.

Abstract: A direct chemical lysis composition includes an assay compatible buffer composition and an assay compatible surfactant. When combined with a specimen storage composition, such compositions prevent undesired modifications to nucleic acid and proteins lysed from cells in the biological sample. Assays of samples from such compositions do not require expensive and time-consuming steps such as centrifugation and prolonged high temperature processing. The direct chemical lysis composition of the present invention permits direct nucleic acid extraction from the cells in the biological sample without the need to decant off the transport media or otherwise exchange the transport media with assay compatible buffers. There is no need to combine the sample with proteinase K or another enzyme to extract nucleic acids from the cells. A method for lysing cells to obtain target nucleic acid for assay and a kit for combining the direct chemical lysis composition with a sample are also contemplated.

Abstract: Optimizing the resource configuration or selection for grant-free contention-based non-orthogonal multiple access (NOMA) transmissions is an effective way to increase network capacity and reduce multi-user interference at the user equipment (UE). In some embodiments, a network node may determine the current traffic load, select multiple access (MA) sequences for the UE based on the determination, and transmit this selection to the UE for subsequent transmissions. In other embodiments, the UE may receive a message with an indication of the traffic load being experienced by the base station that the UE is attempting to connect to, and then may randomly select an MA sequence for subsequent transmissions.

Abstract: An nucleic acid integrated detection reagent tube is provided, it includes a main tube and one or more branch tubes, wherein a lysing zone, a cleaning zone and a plurality of separation plugs comprising at least a least a separation plug and a second separation plug which are sequentially disposed, the first separation plug is used for separating the lysing zone and the cleaning zone, a reaction zone is provided in the branch tubes and the second separation plug is positioned at a connection between the branch tubes and the main tube or inside the branch tubes; hydrophobic layers in a liquid or a solid phase disposed at each of the plurality of separation plugs; and a magnetic bead channel for magnetically carrying the nucleic acid to sequentially pass through each hydrophobic layer penetrating to the branch tubes defined in an inner wall of the detection reagent tube.

Abstract: An nucleic acid integrated detection method is provided, the method includes separating a lysis solution, a cleaning solution and a reaction solution in a detection reagent tube by providing a plurality of separation plugs in an over-under arrangement and disposing a hydrophobic layer in liquid or solid phase on each separation plug; adding a sample into the lysis solution; extracting nucleic acid in the sample using magnetic nanobeads; and then driving the magnetic nanobeads carrying the nucleic acid to sequentially pass through each hydrophobic layer along a magnetic bead channel and into the cleaning solution and the reaction solution to realize a cleaning and amplification for the nucleic acid, and finally, detecting the nucleic acid of the sample by an external device using an optical detection method, thus realizing a plurality of steps of nucleic acid extraction, cleaning and amplification reactions in the same detection reagent tube.

Abstract: An experimental system for studying a refining mechanism and characteristic of a refiner plate, including a disc refiner unit, a first storage tank, a second storage tank, a circulating pump, a pipeline system, a detection device for measuring process variables including flow, pressure and temperature, and a data acquisition and control system. An operation parameter control system is provided to control an operation state of valves at different positions of the pipeline system to achieve the switching of the operation mode of the experimental system. The data acquisition and control system is configured to collect the parameters at different detection points. A method for operating the experimental system is also provided.

Abstract: Provided are a random-access sending and receiving method and apparatus, transmitting end, receiving end, and storage medium. The random-access sending method includes: a preamble resource is acquired, and preamble information is generated; a pilot resource is determined according to the preamble resource and a user equipment identifier, and pilot information is generated; data information is acquired, and the data information is mapped to a time-frequency resource, the data information including user equipment identifier information; and a radio frame is formed from the preamble information, the pilot information and the data information, and the radio frame is sent.

Abstract: A nucleic acid integrated detection method and detection reagent tube are provided, separating a lysis solution, a cleaning solution and a reaction solution in a detection reagent tube by providing a plurality of separation plugs in an over-under arrangement and disposing a hydrophobic layer in liquid or solid phase on each separation plug; adding a sample into the lysis solution; extracting nucleic acid in the sample using magnetic nanobeads; and then driving the magnetic nanobeads carrying the nucleic acid to sequentially pass through each hydrophobic layer along a magnetic bead channel and into the cleaning solution and the reaction solution to realize a cleaning and amplification for the nucleic acid, and finally, detecting the nucleic acid of the sample by an external device using an optical detection method, thus realizing a plurality of steps of nucleic acid extraction, cleaning and amplification reactions in the same detection reagent tube.

Abstract: The present invention discloses a method for designing a refiner plate with equidistant curved bars, comprising following steps of: designing a central bar are of center curved bar and defining the bar angle for the equidistant curved bar; designing circle arcs for curved bars on two sides of center curved bar of equidistant curved bar segment; when the whole refining segment is full of circle arcs, trimming lines of outer circle arcs of the refining segment to complete the design of equidistant circle arcs on the two sides; and if required, dividing the bars into zones. In the present invention, by the definition of the bar angle for the curved bars and the parametric design of the equidistant curved bars by using circle are equations, it is ensured that the flexibility in designing an equidistant curved bar refiner plate is improved.

Abstract: A nucleic acid integrated detection method and detection reagent tube are provided, separating a lysis solution, a cleaning solution and a reaction solution in a detection reagent tube by providing a plurality of separation plugs in an over-under arrangement and disposing a hydrophobic layer in liquid or solid phase on each separation plug; adding a sample into the lysis solution; extracting nucleic acid in the sample using magnetic nanobeads; and then driving the magnetic nanobeads carrying the nucleic acid to sequentially pass through each hydrophobic layer along a magnetic bead channel and into the cleaning solution and the reaction solution to realize a cleaning and amplification for the nucleic acid, and finally, detecting the nucleic acid of the sample by an external device using an optical detection method, thus realizing a plurality of steps of nucleic acid extraction, cleaning and amplification reactions in the same detection reagent tube.

Abstract: Methods for predicting the development of sepsis in a subject at risk for developing sepsis are provided. In one method, features in a biomarker profile of the subject are evaluated. The subject is likely to develop sepsis if these features satisfy a particular value set. Methods for predicting the development of a stage of sepsis in a subject at risk for developing a stage of sepsis are provided. In one method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to have the stage of sepsis if these feature values satisfy a particular value set. Methods of diagnosing sepsis in a subject are provided. In one such method, a plurality of features in a biomarker profile of the subject is evaluated. The subject is likely to develop sepsis when the plurality of features satisfies a particular value set.

Abstract: Provided are a random-access sending and receiving method and apparatus, transmitting end, receiving end, and storage medium. The random-access sending method includes: a preamble resource is acquired, and preamble information is generated; a pilot resource is determined according to the preamble resource and a user equipment identifier, and pilot information is generated; data information is acquired, and the data information is mapped to a time-frequency resource, the data information including user equipment identifier information; and a radio frame is formed from the preamble information, the pilot information and the data information, and the radio frame is sent.