Abstract: A biopsy device comprises a probe assembly, a holster assembly, a tissue sample holder, and a manually operated rotation mechanism configured to rotate the tissue sample holder. The probe assembly comprises a cutter configured to sever a tissue sample. The tissue sample holder includes a plurality of tissue chambers configured to receive discrete severed tissue samples. The holster assembly comprises the non-motorized, manually operated rotation mechanism configured to allow a user to align consecutive chambers to successively collect discrete severed tissue samples. The tissue sample holder rotation mechanism may comprise a first button, a first lever, a first pawl, a first ratchet, an indexing shaft, and a first gear, which are all configured to, ultimately, rotate a tissue sample holder. The tissue sample holder rotation mechanism may alternately include thumbwheels, a worm gear, or a ratcheting lever, among other things.

Abstract: An improved catalytic process for the production of pyridine carboxylic acid amides, by catalytic hydration reaction of pyridine nitriles with solid heterogeneous catalyst wherein the process involve effective utilization and recycling of the catalytic components, and reactants.

Abstract: The present invention provides a novel process for the preparation of substituted optically pure (S)-(+)- or (R)-(?)-10-hydroxy-dihydrodibenz[b,f]azepines or derivatives thereof, starting from 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepines using boronate esters or their derivatives. The present invention also provides use of thus prepared (S)-(+)- or (R)-(?)-10-hydroxy-dihydrodibenz[b,f]azepines for the preparation of their ester such as (S)-(?)-10-acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide or (R)-(+)-10-acetoxy-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide. The present invention also provides novel solid state crystalline forms J1, J2, J3, J4 and amorphous form of eslicarbazepine and the process for the preparation thereof. Also, the present invention provides novel solid state crystalline form and amorphous form of eslicarbazepine acetate and the process for the preparation thereof.

Abstract: Client-side sharing of event information. Via a service hub executed on a client device, an event generated by a first web application accessed by the client device can be received and communicated to a second web application accessed by the client device or communicated to a native application executed on the client device. The event is not routed through a server.

Abstract: Disclosed herein cost effective and ecofriendly large scale process for producing pyridine carboxylic acid with high purity and yield at industrial scale.

Abstract: A data stream management system (DSMS) is designed to support a new user-defined function, by creating and using at least two structures as follows. A first structure (“metadata entry”) is created in response to a command for creation of the new function, and maps a single instance of a class to the function's name. A second structure is created with creation of an operator on receipt of each new continuous query that uses the new function. The second structure (“operator specific data structure”) contains a path to the newly-created instance, which path is obtained by looking up the first structure. Additional second structures are created on receipt of additional continuous queries which use the new function, but all second structures contain the same path. All continuous queries use the same instance. Repeated use of a single instance to compile and execute multiple queries eliminates repeated instantiation of the same function.

Abstract: A computer is programmed to accept a command for creation of a new aggregation defined by a user to process data incrementally, one tuple at a time. One or more incremental function(s) in a set of instructions written by the user to implement the new aggregation maintain(s) locally any information that is to be passed between successive invocations, to support computing the aggregation for a given set of tuples as a whole. The user writes a set of instructions to perform the aggregation incrementally, including a plus function which is repeatedly invoked, only once, for each addition to a window of a message. The user also writes a minus function to be invoked with the message, to return the value of incremental aggregation over the window after removal of the message. In such embodiments, the computer does not maintain copies of messages in the window for use by aggregation function(s).

Abstract: A circuit for providing audio signals to a load such as a speaker is provided that uses the speaker or headphone amplifier structure as a current to voltage converter, thereby eliminating a separate current to voltage converter from the circuit. Such a design removes one of the elements that creates noise in the circuit architecture and improves the dynamic range for the audio signal. For example, the output of a digital to analog converter is a single ended output provided to the speaker or headphone amplifier. The digital to analog converter can include a series of current sources that are summed up to provide the single ended output. Where the current sources have positive and negative current source mismatch, a feedback mechanism is employed to correct for the mismatch and reduce introduction of harmonic noise into the signal through the digital to analog converter.

Abstract: Disclosed herein are novel intermediates and process for large scale production of (S)-3-[(1-dimethylamino)ethyl]phenyl-N-ethyl-N-methyl-carbamate (rivastigmine) or its pharmaceutically acceptable salts employing the novel intermediates. Further provided are methods for producing the novel intermediates thereof.

Abstract: A telecommunication receiver provided according to the present invention is implemented to receive a first signal containing information and noise on a first set of sensors and a second signal containing only noise on a second set of sensors. Receiver then decodes the information using first signal and second signal. In one embodiment, a bonded DSL receiver with k signals sensors is implemented with additional s number of noise only sensors to receive only noise. Accordingly, joint demodulation is performed using signals received on k signals sensors and s noise only sensors. The noise sensor is implemented in common mode.

Abstract: A new continuous query to a data stream management system (DSMS) may use several operators that are equivalent to operators currently being used by continuous queries that have been previously registered in the DSMS. To determine equivalence of operators, the DSMS checks at least the function and the data input to the operators. On finding equivalence, the DSMS modifies a global plan being executed, to use at least an existing subtree of operators during execution of the new continuous query, to generate a modified plan. The DSMS is also programmed to cause each relation source operator (which outputs a relation) to propagate a current state of the relation to each operator newly coupled to the relational operator. After propagation of current state to newly-coupled operators, each operator in the modified plan processes any new data and supplies the result to all operators coupled thereto, including newly-coupled operators and existing operators.

Abstract: A computer is programmed to accept a command to create a new aggregation defined by a user during execution of continuous queries on streams of data. The computer is further programmed to thereafter accept and process new continuous queries using the new aggregation, in a manner similar to built-in aggregations. The user typically writes a set of instructions to perform the new aggregation, and identifies in the command, a location of the set of instructions. In response to such a command, the computer creates metadata identifying the new aggregation. The metadata is used to instantiate one aggregation for each group of data in a current window, grouped by an attribute identified in a new query.

Abstract: Disclosed herein cost effective and ecofriendly large scale process for producing pyridine carboxylic acid with high purity and yield at industrial scale.

Abstract: Disclosed herein the process for producing 1-benzyl-4-[(5,6-dimethoxy-1-indanon-2yl)methyl]piperidine or its salt thereof employing novel intermediates.

Abstract: A data stream management system (DSMS) is designed to support a new user-defined function, by creating and using at least two structures as follows. A first structure (“metadata entry”) is created in response to a command for creation of the new function, and maps a single instance of a class to the function's name. A second structure is created with creation of an operator on receipt of each new continuous query that uses the new function. The second structure (“operator specific data structure”) contains a path to the newly-created instance, which path is obtained by looking up the first structure. Additional second structures are created on receipt of additional continuous queries which use the new function, but all second structures contain the same path. All continuous queries use the same instance. Repeated use of a single instance to compile and execute multiple queries eliminates repeated instantiation of the same function.

Abstract: Residual FEXT resulting from intended and/or inherent partial cancellation of crosstalk in vectored DSL systems impairs upstream power back-off (UPBO) as traditionally implemented. By considering and taking into account the effects of residual crosstalk on vectored DSL system performance and operation, improved data rates and/or other vectored DSL system performance are realized through the use of UPBO parameters generated for a given residual FEXT environment.

Abstract: Disclosed herein are novel intermediates and process for large scale production of (S)-3-[(1-dimethylamino)ethyl]phenyl-N-ethyl-N-methyl-carbamate (rivastigmine) or its pharmaceutically acceptable salts employing the novel intermediates. Further provided are methods for producing the novel intermediates thereof.

Abstract: The present invention is an improved high efficiency internal combustion engine (IHEICE) which results in higher efficiency due to its design, or respective relation of its parts. In the IHEICE, the energy fuel produced after combustion is harnessed and exploited to its highest potential when the engine starts exploiting the power after extended Top Down Center (ETDC). The main improvement in the IHEICE is the fitting and arrangement of the piston connecting rod and the crank; that is, the arrangement of the piston with respect to the crank, with the internal fitting design being the same. In the traditional arrangement, a problem is created in exploiting power from 60 degrees and beyond because a displacement (gap) is created inside the head resulting from the downward movement of the piston (60 degree movement of the crank). To fill this gap, the connecting rod, with a timer/cam and wheels, is used.

Abstract: A data stream management system (DSMS) is designed to support a new user-defined function, by creating and using at least two structures as follows. A first structure (“metadata entry”) is created in response to a command for creation of the new function, and maps a single instance of a class to the function's name. A second structure is created with creation of an operator on receipt of each new continuous query that uses the new function. The second structure (“operator specific data structure”) contains a path to the newly-created instance, which path is obtained by looking up the first structure. Additional second structures are created on receipt of additional continuous queries which use the new function, but all second structures contain the same path. All continuous queries use the same instance. Repeated use of a single instance to compile and execute multiple queries eliminates repeated instantiation of the same function.

Abstract: A process recovers of pyridine and/or its derivatives from their aqueous mass and/or manufacturing reaction mass by liquid-liquid extraction employing an alkyl acetate. The process further involves effective recovering and recycling of solvents from the aqueous phase and other waste obtained during the process.