Patents by Inventor Shaopeng Wang

Shaopeng Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing the antiviral agent [1S-(1alpha, 3alpha, 4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one
    Publication number: 20060106216
    Abstract: Processes are disclosed for preparing the antiviral agent entecavir. A resin adsorption process for the isolation and purification of entecavir is also disclosed. Various intermediates useful in the preparation of entecavir are also disclosed.
    Type: Application
    Filed: December 19, 2005
    Publication date: May 18, 2006
    Inventors: Yadagiri Pendri, Chung-Pin Chen, Jing Liang, Shaopeng Wang, Milan Stojanovic, Richard Polniaszek, John Thottathil, Dhileepkumar Krishnamurty
  • Process for preparing the antiviral agent [1S-(1alpha,3 alpha,4beta )]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one
    Patent number: 7034152
    Abstract: Processes are disclosed for preparing the antiviral agent entecavir. A resin adsorption process for the isolation and purification of entecavir is also disclosed. Various intermediates useful in the preparation of entecavir are also disclosed.
    Type: Grant
    Filed: December 11, 2003
    Date of Patent: April 25, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Yadagiri R. Pendri, Chung-Pin H. Chen, Sunil S. Patel, Jeffrey M. Evans, Jing Liang, David R. Kronenthal, Gerald L. Powers, Siva Josyula Prasad, Jeffrey T. Bien, Zhongping Shi, Ramesh N. Patel, Amit Banerjee, Yeung Yu Chan, Sushil K. Rijhwani, Ambarish K. Singh, Shaopeng Wang, Milan Stojanovic, David J. Kucera, Richard P. Polniaszek, Charles Lewis, John Thottathil, Dhileepkumar Krishnamurty, Maotang X. Zhou, Purushotham Vemishetti
  • Method of preparation of 21-amino epothilone derivatives
    Patent number: 6930187
    Abstract: An improved method of synthesis of 21-amino epothilone derivatives which provides a one-pot conversion of 21-hydroxy epothilones to highly desirable 21-amino epothilones in high yield.
    Type: Grant
    Filed: February 13, 2003
    Date of Patent: August 16, 2005
    Assignee: Bristol-Myers Squibb Company
    Inventors: Denis Favreau, Joydeep Kant, Kathia Levesque, Shaopeng Wang, Zhengrong Guo, Brian Leslie James
  • Nanoparticle thermometry and pressure sensors
    Publication number: 20050169348
    Abstract: A nanoparticle fluorescence (or upconversion) sensor comprises an electromagnetic source, a sample and a detector. The electromagnetic source emits an excitation. The sample is positioned within the excitation. At least a portion of the sample is associated with a sensory material. The sensory material receives at least a portion of the excitation emitted by the electromagnetic source. The sensory material has a plurality of luminescent nanoparticles luminescing upon receipt of the excitation with luminance emitted by the luminescent nanoparticles changing based on at least one of temperature and pressure. The detector receives at least a portion of the luminance emitted by the luminescent nanoparticles and outputs a luminance signal indicative of such luminance. The luminescence signal is correlated into a signal indicative of the atmosphere adjacent to the sensory material.
    Type: Application
    Filed: June 12, 2003
    Publication date: August 4, 2005
    Inventors: Wei Chen, Shaopeng Wang, Sarah Westcott
  • Process for preparing the antiviral agent [1S-(1alpha,3 alpha,4beta)]-2-amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one
    Publication number: 20040192912
    Abstract: Processes are disclosed for preparing the antiviral agent entecavir. A resin adsorption process for the isolation and purification of entecavir is also disclosed. Various intermediates useful in the preparation of entecavir are also disclosed.
    Type: Application
    Filed: December 11, 2003
    Publication date: September 30, 2004
    Inventors: Yadagiri R. Pendri, Chung-Pin H. Chen, Sunil S. Patel, Jeffrey M. Evans, Jing Liang, David R. Kronenthal, Gerald L. Powers, Siva Josyula Prasad, Jeffrey T. Bien, Zhongping Shi, Ramesh N. Patel, Amit Banerjee, Yeung Yu Chan, Sushil K. Rijhwani, Ambarish K. Singh, Shaopeng Wang, Milan Stojanovic, David J. Kucera, Richard P. Polniaszek, Charles Lewis, John Thottathil, Dhileepkumar Krishnamurty, Maotang X. Zhou, Purushotham Vemishetti
  • Method of preparation of 21-amino epothilone derivatives
    Publication number: 20030187039
    Abstract: An improved method of synthesis of 21-amino epothilone derivatives which provides a one-pot conversion of 21-hydroxy epothilones to highly desirable 21-amino epothilones in high yield.
    Type: Application
    Filed: February 13, 2003
    Publication date: October 2, 2003
    Inventors: Denis Favreau, Joydeep Kant, Kathia Levesque, Shaopeng Wang, Zhengrong Guo, Brian Leslie James
  • Preparation of 3-substituted-4-arylquinolin-2-one derivatives
    Patent number: 6353119
    Abstract: The present invention relates to a process for the preparation of 3-substituted-4-arylquinolin-2-one derivatives from a substituted coumarin and using a photochemical cyclization method on a dihydrofuran intermediate.
    Type: Grant
    Filed: November 28, 2000
    Date of Patent: March 5, 2002
    Assignee: Bristol-Myers Squibb Company
    Inventors: Gerard A. Crispino, Shaopeng Wang, Jun Li
  • 7-oxabicycloheptane carboxylic acid prostaglandin analog intermediates useful in the preparation of anti-thrombotic and anti-vasospastic compounds and method for preparing same
    Patent number: 5618946
    Abstract: The present invention relates to novel 7-oxabicycloheptane carboxylic acid prostaglandin analog intermediates which may be used to prepare a final anti-thrombotic, anti-vasospastic product, and to methods for preparing the same.
    Type: Grant
    Filed: February 29, 1996
    Date of Patent: April 8, 1997
    Assignee: Bristol-Myers Squibb Company
    Inventors: Michael A. Poss, Paul D. Pansegrau, Shaopeng Wang, John K. Thottathil, Janak Singh, Richard H. Mueller
  • 7-Oxabicycloheotane carboxylic acid prostaglandin analog intermediates useful in the preparation of anti-thrombotic and anti-vasospastic compounds and method for preparing same
    Patent number: 5539130
    Abstract: A method is provided for preparing carboxylic acid intermediates of the structure ##STR1##
    Type: Grant
    Filed: September 14, 1995
    Date of Patent: July 23, 1996
    Assignee: Bristol-Myers Squibb Company
    Inventors: Michael A. Poss, Paul D. Pansegrau, Shaopeng Wang, John K. Thottahil, Janak Singh, Richard H. Mueller
  • 7-oxabicycloheptane carboxylic acid prostaglandin analog intermediates useful in the preparation of anti-thrombotic and anti-basopastic compounds and method for preparing same
    Patent number: 5512690
    Abstract: A method is provided for preparing carboxylic acid intermediates of the structure ##STR1##
    Type: Grant
    Filed: September 14, 1995
    Date of Patent: April 30, 1996
    Assignee: Bristol-Myers Squibb Company
    Inventors: Michael A. Poss, Paul D. Pansegrau, Shaopeng Wang, John K. Thottathil, Janak Singh, Richard H. Mueller
  • 7-oxabicycloheptane carboxylic acid protaglandin analog intermediates useful in the preparation of anti-thrombotic and anti-vasospastic compounds and method for preparing same
    Patent number: 5508445
    Abstract: A method is provided for preparing carboxylic acid intermediates of the structure ##STR1##
    Type: Grant
    Filed: December 15, 1994
    Date of Patent: April 16, 1996
    Assignee: Bristol-Myers Squibb Company
    Inventors: Michael A. Poss, Paul D. Pansegrau, Shaopeng Wang, John K. Thottathil, Janak Singh, Richard H. Mueller
  • 7-oxabicycloheptane carboxylic acid prostaglandin analog intermediates useful in the preparation of anti-thrombotic and anti-vasospastic compounds and method for preparing same
    Patent number: 5399725
    Abstract: A method is provided for preparing carboxylic acid intermediates of the structure ##STR1## wherein an aldehyde of the structure ##STR2## is prepared and subjected to a Horner-Emmons reaction to form the ester of the structure ##STR3## and the ester is hydrogenated to the carboxylic acid which may be used in making the final anti-thrombotic--anti-vasospastic compounds.
    Type: Grant
    Filed: April 20, 1994
    Date of Patent: March 21, 1995
    Assignee: Bristol-Myers Squibb Co.
    Inventors: Michael A. Poss, Paul D. Pansegrau, Shaopeng Wang, John K. Thottathil, Janak Singh, Richard H. Mueller