Abstract: Systems and methods for providing a user interface that facilitates application development. The applications may utilize one or more underlying machine-learning models to perform application functions. Exemplary implementations may: effectuate presentation of an application development interface to developers through client computing platforms associated with the developers; receive, from client computing devices, input information indicating feature values entered and/or selected by the developers via the user interface fields; responsive to receipt of first input information, configure a first application in accordance with the feature values included in a first feature values set; provide the configured application for user by one or more users; and/or other exemplary implementations.

Abstract: A blockchain-based exchange system includes a distributed group of computers operating a distributed consensus algorithm and having a distributed ledger. The system enables trades to be recorded on the distributed ledger. The system performs operations including receiving, from a first user, a deposit of a first value, converting the first value into a first pool token, adding the first value to a first pool, receiving, from a second user, a deposit of a second value.

Abstract: An apparatus for removably applying insulative material to magnetic surfaces includes a sheet of insulative material. In some embodiments, snap fasteners are affixed thereto and, in some embodiments, magnets are directly affixed to the insulative material using adhesive. In embodiments using snap fasteners, each snap fastener has an eyelet and a socket such that a shaft of the eyelet passes through the sheet of insulative material and is held in an orifice of the socket. The socket has a cup-shaped area on a side that is opposite to the orifice. There are magnets, each of which is affixed to the cup-shaped area of the socket such that the sheet of insulative material is then removably attached to a magnetic material by the magnets.

Abstract: Described herein are techniques of using machine learning to automatically extract clinical variable values for subjects from clinical record data. The techniques designate certain clinical variables as hybrid variables that can be assigned values by machine learning model prediction. The techniques process, using a machine learning model trained to predict a value of a hybrid variable, clinical record data associated with a subject to obtain a predicted hybrid variable value and an associated confidence score. The techniques set the value of the hybrid variable for the subject to the predicted hybrid variable value when the model prediction is of sufficiently high confidence.

Abstract: Compounds that inhibit p38? MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases.

Abstract: Compounds that inhibit p38? MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases.

Abstract: A system and method for analysing a data set based on ranking of observations is disclosed. The method includes uploading the data set by a user and selecting one or more significant variables in the data set that interests the user and represents a priority & focus of a study. The method further includes automatically selecting an appropriate statistical technique based on the type of the variable for performing a correlation analysis for measuring an interdependence of one or more variables associated with the data set and assessing a magnitude of the relationship between the one or more variables. The method further includes performing a correlation for generating one or more correlation results. The method further includes returning a list of key analysis to the user, based on the one or more significant variables and the one or more correlation results.

Abstract: A FET switch stack and a method to operate a FET switch stack. The FET switch stack includes a stacked arrangement of body bypass FET switches connected across respective common body resistors. The body bypass FET switches bypass the respective common body resistors during the OFF steady state of the FET switch stack and do not bypass the respective common body resistors during the ON steady state.

Abstract: Embodiments of the present invention set forth systems, apparatuses and methods for providing multiple spins during gaming events to provide increased opportunities to receive winning outcomes. Accordingly, a gaming device can be configured to have a plurality of reels with multiple symbols on each reel. A portion of the symbols on each reel are displayed on a game grid having a number of symbol positions. During a gaming event, the symbols are randomly arranged via a first spin on game grid to generate a first configuration and a determination is made as to whether the first condition satisfies a predetermined condition. When the predetermined condition is satisfied, the reels or symbols in the symbol positions associated with the predetermined condition are held while the remaining reels or symbol positions are subjected to a second spin to randomly generate a second configuration.

Abstract: Certain embodiments are directed to systems and methods for automatically providing data indicative of one or more characteristics of services that may be recommended to a particular patient, wherein the services are executable at least in part electronically based on data generated and provided by a system for facilitating access to the services. The generated data may be utilized for generating one or more user interfaces providing data regarding derived standard pricing data that is automatically assigned to the referred services and which may be attributable to a patient based at least in part on the patient's usage of the services.

Abstract: A three dimensional magnetic sensor attached to a surgical nail is located based on an applied monotonic magnetic field gradient. Another three dimensional magnetic sensor locates a surgical drill. A display generates a real time image of the relative alignment of the surgical drill and of the surgical nail, allowing a surgeon to repair bone fractures.

Abstract: Antigen binding agents (e.g., single domain antibodies) that bind guanylyl cyclase C (GCC) and chimeric antigen receptors comprising GCC antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions comprising these antigen binding agents and fragments thereof are also disclosed. The invention also provides therapeutic methods for utilizing the antibodies and antigen-binding molecules are provided herein.

Abstract: A system for determining corrosion under insulation of an industrial asset is provided. The system includes an infrared camera configured to acquire one or more time-series infrared images of an industrial asset. The system further includes a computing device configured to receive data characterizing the one or more time-series infrared images, and to identify an area of interest of the industrial asset within the one or more time-series infrared images. The computing device further configured to identify, by a machine learning algorithm, a plurality of defects within the area of interest based on pixel-wise assignment of at least one defect category selected from a plurality of defect categories associated with corrosion under insulation of the industrial asset, and to provide the plurality of defects within the area of interest of the industrial asset. Related methods, apparatuses, and computer-readable mediums are also provided.

Abstract: The present invention provides a method for preparing a compound of Formula C, Formula D, or Formula F: wherein each R1, R2, and R3 is independently H, SFs, N(C1-C8 alkyl)(C1-C8 alkyl), C(?S)N(C1-C8 alkyl)(C1-C8 alkyl), SO2N(C1-C8 alkyl)(C1-C8 alkyl), OSO2(C1-C8 alkyl), OSO2N(C1-C8 alkyl)(C1-C8 alkyl), N(C1-C8 alkyl)SO2(C1-C8 alkyl), or C1-C8 alkyl, C1-C8 haloalkyl, C2-C8 alkenyl, C2-C8 alkynyl, C3-C10 cycloalkyl, C3-C10 halocycloalkyl, C4-C10 alkylcycloalkyl, C4-C10 cycloalkylalkyl, C6-C14 cycloalkylcycloalkyl, C5-C10 alkylcycloalkylalkyl, C3-C8 cycloalkenyl, C1-C8 alkoxy, C1-C8 haloalkoxy, C3-C8 cycloalkoxy, C3-C8 halocycloalkoxy, C4-C10 cycloalkylalkoxy, C2-C8 alkenyloxy, C2-C8 alkynyloxy, C1-C8 alkylthio, C1-C8 alkylsulfinyl, C1-C8 alkylsulfonyl, C3-C8 cycloalkylthio, C3-C8 cycloalkylsulfinyl, C3-C8 cycloalkylsulfonyl, C4-C10 cycloalkylalkylthio, C4-C10 cycloalkylalkylsulfinyl, C4-C10 cycloalkylalkylsulfonyl, C2-C8 alkenylthio, C2-C8 alkenylsulfinyl, C2-C8 alkenylsulfonyl, C2-C8 alkynylthio, C2-C8 alk

Abstract: Methods and systems for dynamic bookmarking in branched video are described. An application provides a video tree having a plurality of video segments, with each video segment including a predefined portion of one or more paths in the video tree, and each path being associated with a different video presentation. One of the paths in the video tree is traversed based on one or more decisions made by a user during playback of the video presentation associated with the path being traversed. A selection of a particular location in the path being traversed is received by the application, which stores a bookmark of the location for subsequent retrieval. The bookmark identifies a sequence of video segments in the video tree having been traversed to reach the location. The structure of the video tree is modified, and the bookmark is automatically updated, if necessary. At a later time, the application receives a selection of the stored bookmark and seeks to the bookmarked location.

Abstract: The present disclosure provides pyrimidine dione compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors. The compounds can be used alone or in combination with other anti-cancer agents.

Abstract: A method of performing a lab developed test for detecting a nucleic acid analyte on an automated analyzer. The method includes a first step of using a computer to select, define or modify one or more user-defined parameters of a protocol for performing the lab developed test on the analyzer, where each user-defined parameter of the protocol defines a step to be performed by the analyzer during the lab developed test. The method further includes a second step of performing the lab developed test with the protocol of the first step, where the analyzer stores one or more system-defined parameters for performing the lab developed test, the one or more system-defined parameters being installed on the analyzer prior to performing first step.

Abstract: A method, system, and device for magnetically pushing agents into an eye. The agents are magnetic or magnetizable or magnetically responsive.

Abstract: Ceramic matrix composite articles include, for example a first plurality of plies of ceramic fibers in a ceramic matrix defining a first extent, and a local at least one second ply in said ceramic matrix defining a second extent on and/or in said first plurality of plies with the second extent being less than said first extent. The first plurality of plies has a first property, the at least one second ply has at least one second property, and said first property being different from said at least one second property. The different properties may include one or more different mechanical (stress/strain) properties, one or more different thermal conductivity properties, one or more different electrical conductivity properties, one or more different other properties, and combinations thereof.

Abstract: A system and related methods are disclosed for managing, evaluating and improving identity governance and administration. The system is configured to execute a method, which includes receiving, by a computing system, data associated with the identity governance and administration, classifying, by a computing system, the data associated with the identity governance and administration according to one or more rules, generating, by a computing system, a three-dimensional model using the classified data associated with the identity governance and administration, performing, by a computing system, a statistical analysis, and optionally displaying, by a computing system, the three-dimensional model or results of the statistical analysis, or both.