Abstract: Laminates made with an adhesive comprised of a polymerizable composition containing compounds based on N-acylamido-piperazines are provided. Such compounds have the formula: ##STR1## wherein: R.sup.1, R.sup.2, and R.sup.3 are each independently selected from the group consisting of hydrogen and lower alkyl;B is a linking group selected from the group consisting of carbonyl, sulfonyl, amide, and carboxyl;n is one or zero; andR.sup.4 is a radical selected from the group consisting of a higher aliphatic group (i.e. at least four carbon atoms, preferably from about 6 to about 50 carbon atoms), a substituted higher aliphatic group, an alicyclic group, a heterocyclic group, a non-benzenoid aromatic group, and a substituted aromatic group. The adhesive coating is exposed to ultra-violet radiation sufficient to cause the compound to polymerize and thus cure the adhesive.

Abstract: A zipper strip for a reclosable package having a transverse zipper is provided. The zipper strip comprises a male interlocking profile and a female interlocking profile. Each profile includes an interlocking member and an integral web which defines a leading flange. The leading flanges are sealed to thermoplastic film material which is used to make the reclosable packages and to each other. One of leading flanges is provided with a perforation along its length so that it can be separated by pulling the profiles apart.

Abstract: A zipper strip for a reclosable package having a transverse zipper is provided. The zipper strip comprises a male interlocking profile and a female interlocking profile. Each profile includes an interlocking member and an integral web which defines a trailing flange. One or both of the profiles are provided with high compression members which allow one or both of the interlocking members to be sealed to thermoplastic film without being crushed or distorted.

Abstract: A reclosable package for a consumer product includes a zipper strip having male and female interlocking profiles. The former has a male interlocking member having a cross section in the shape of an asymmetric arrowhead. The latter has a female interlocking member in the form of two mutually curving members defining a channel therebetween. The male interlocking member is snappingly engaged into the channel to reclose the package. The asymmetric male interlocking member has an acute edge outward of the interior of the package, and a rounded edge facing the inside of the package. This asymmetry makes the package easier to open from within than from without.

Abstract: A method for attaching reclosable zipper strips transversely to thermoplastic film material which may be used to make reclosable bags or packages in a form-fill-seal machine is claimed. The zipper strip includes a male profile and a female profile. The male profile includes a male interlocking member and an integral web comprising a trailing flange and, optionally, a leading flange. Likewise, the female profile includes a female interlocking member and an integral web comprising a trailing flange and, optionally, a leading flange. As the film material is advanced into the form-fill-seal machine in bag length increments, the interlocked zipper strip is disposed on the film material transversely thereto with the trailing flange oriented in a direction opposite to the motion of the film material. The zipper strip is then sealed to the film material at its extremities. In this manner the male and female profiles are sealed to each other and to the film material.

Abstract: The present invention concerns a process for improving doxorubicin production by means of a recombinant Streptomyces peucetius strain bearing a mutation in the gene dnrU coding for a protein involved in the metabolism of daunorubicin.

Abstract: A peel seal zipper tape for reclosable plastic bags or packages includes a first and a second mutually interlocking zipper profile disposed on a top surface of a laminated film strip. The top surface is formed by a layer of a sealant material. The laminated film strip also has a middle layer, or core, of a material stiffer than the first and second mutually interlocking zipper profiles, and may also have a bottom layer of a sealant material. In use, the laminated film strip is folded over, and the zipper profiles are interlocked with one another. In doing so, portions of the top surface of the laminated film strip face inwardly, so that the folded film strip may be closed with a heat seal. The outside of the folded peel seal zipper tape, that is, the bottom layer of sealant material is bonded to plastic sheet material from which reclosable plastic bags or packages are made. In the production of the bags or packages, the mutually facing portions of the laminated film strip are sealed together.

Abstract: Polymerizable compositions containing compounds based on N-acylamido-piperazines are provided. Such compounds have the formula: ##STR1## wherein: R.sup.1, R.sup.2, and R.sup.3 are each independently selected from the group consisting of hydrogen and lower alkyl,B is a linking group selected from the group consisting of carbonyl, sulfonyl, amide, and carboxyl;n is one or zero;R.sup.4 is a radical selected from the group consisting of a higher aliphatic group (i.e. at least four carbon atoms, preferably from about 6 to about 50 carbon atoms), a substituted higher aliphatic group, an alicyclic group, a heterocyclic group, a non-benzenoid aromatic group, and a substituted aromatic group. Compositions containing these compounds which are stable against gelation can be prepared. The compound is preferably present in said composition in a major amount on a mole percent basis of the polymerizable monomers.

Abstract: A peel seal zipper tape for reclosable plastic bags or packages includes a first and a second mutually interlocking zipper profile disposed on a top surface of a laminated film strip. The top surface is formed by a layer of a sealant material. The laminated film strip also has a middle layer, or core, of a material stiffer than the first and second mutually interlocking zipper profiles, and may also have a bottom layer of a sealant material. In use, the laminated film strip is folded over, and the zipper profiles are interlocked with one another. In doing so, portions of the top surface of the laminated film strip face inwardly, so that the folded film strip may be closed with a heat seal. The outside of the folded peel seal zipper tape, that is, the bottom layer of sealant material is bonded to plastic sheet material from which reclosable plastic bags or packages are made. In the production of the bags or packages, the mutually facing portions of the laminated film strip are sealed together.

Abstract: The ability to convert daunorubicin to doxorubicin can be conferred on a host cell by transformation with a recombinant vector comprising DNA encoding daunorubicin 14-hydroxylase. The host cell can then be used to produce doxorubicin.

Abstract: A peel seal zipper tape for reclosable plastic bags or packages includes a first and a second mutually interlocking zipper profile disposed on a top surface of a laminated film strip. The top surface is formed by a layer of a sealant material. The laminated film strip also has a bottom surface formed by a layer of a non-peel-seal material. In use, the laminated film strip is folded over enabling the zipper profiles to be interlocked with one another. In so doing, portions of the top surface of the laminated film strip face one another, so that they may be joined with a heat seal. The outside of the folded peel seal zipper tape, that is, the bottom surface of non-peel-seal material, is bonded to plastic sheet material from which reclosable plastic bags or packages are made. In the production of the bags or packages, the mutually facing portions of the laminated film strip are sealed together. The resulting seal gives a visual indication of having been broken when initially opened.

Abstract: Polymerizable compounds based on N-acylamido-piperazines are provided. Such compounds have the formula: ##STR1## wherein: a, b, c and d are independently 0 or 1 and the sum of a, b, c and d is at least 3.R.sup.1, R.sup.2, and R.sup.3 are hydrogen and/or lower alkyl,B.sup.1, B.sup.2, B.sup.3, and B.sup.4 are independently carbonyl, sulfonyl, amide, or carboxyl;m, n, x, and y are independently one or zero;R.sup.23 is a group selected from, substituted and unsubstituted phenyl and phenonyl.These compounds are particularly useful as polymerizable monomers in radiation curable coatings. The compound preferably has at least one group ##STR2## substituted on R.sup.23 wherein M is H or a counterion to the carboxyl group which can be present in place of a ##STR3## group.

Abstract: Polymerizable compounds based on N-acylamido-piperazines are provided. Such compounds have the formula: ##STR1## wherein: R.sup.1, R.sup.2, and R.sup.3 are each independently selected from the group consisting of hydrogen and lower alkyl,B is a linking group selected from the group consisting of carbonyl, sulfonyl, amide, and carboxyl;n is one or zero;R.sup.4 is a radical selected from the group consisting of a higher aliphatic group (i.e. at least four carbon atoms, preferably from about 6 to about 50 carbon atoms), a substituted higher aliphatic group, an alicyclic group, a heterocyclic group a non-benzenoid aromatic group, and a substituted aromatic group. These compounds can be incorporated into a polymerizable composition. The compounds is preferably present in said composition in a major amount on a mole percent basis of th polymerizable monomers. These polymerizable compositions are useful as coatings, particularly in formulations containing a photoinitiator susceptible to ultra-violet radiation.

Abstract: The ability to convert daunorubicin to doxorubicin can be conferred on a host cell by transformation with a recombinant vector comprising DNA encoding daunorubicin 14-hydroxylase. The host cell can then be used to produce doxorubicin.

Abstract: A protective covering for a ladder consisting of two portions of a protective material on either side of an elastic portion of material. The protective covering is attached along the edges of the protective covering by cords or hook and loop fastening straps.

Abstract: An animal fat replacement product of an aqueous gel of one or more dextrins, each of dextrose equivalent less than 20, entrapped in a matrix of an alginate, gum, pectin or Konjae can be effectively used in meats and meat products without adverse organoleptic consequences. The fat mimetic, which can be generally used to replace animal fats, provides excellent lubricity and juiciness while being "rendered" under appropriate conditions, thus behaving quite similarly to animal fat. The animal fat replacement product also is an excellent vehicle for incorporation of other agents often added to meats, such as flavors, colors, preservatives, and so forth.

Abstract: Polymerizable compounds based on N-acylamido-piperazines are provided. Such compounds have the formula: ##STR1## wherein: R.sup.1, R.sup.2, and R.sup.3 are each independently selected from the group consisting of hydrogen and lower alkyl,B is a linking group selected from the group consisting of carbonyl, sulfonyl, amide, and carboxyl;n is ore or zero;R.sup.4 is a radical selected from the group consisting of a higher aliphatic group (i.e. at least four carbon atoms, preferably from about 6 to about 50 carbon atoms), a substituted higher aliphatic group, an alicyclic group, a heterocyclic group, a non-benzenoid aromatic group, and a substituted aromatic group. These compounds can be incorporated into a polymerizable composition. The compound is preferably present in said composition in a major amount on a mole percent basis of the polymerizable monomers. These polymerizable compositions are useful as coatings, particularly in formulations containing a photoinitiator susceptible to ultra-violet radiation.

Abstract: Aqueous compositions comprised of a major amount of water and a minor amount of a polymerizable compound based on N-acryloyl-piperazine are provided. Such compounds have the formula: ##STR1## wherein: R.sup.1, R.sup.2, and R.sup.3 are each independently selected from the group consisting of hydrogen and lower alkyl,B is a linking group selected from the group consisting of carbonyl, sulfonyl, amide, and carboxyl;n is one or zero;R.sup.4 is a radical selected from the group consisting of a higher aliphatic group (i.e. at least four carbon atoms, preferably from about 6 to about 50 carbon atoms), a substituted higher aliphatic group, an alicyclic group, a heterocyclic group, a non-benzenoid aromatic group, and a substituted aromatic group. These compounds can be used as an emulsifier in emulsion polymerization.

Abstract: A method of providing a clear image on a component including the steps of providing a transparent member having first and second opposite sides, providing a layer of opaque material on the second side of the transparent member and ablating away a predetermined pattern of the opaque layer by directing a laser beam at portions of the first side of the transparent member corresponding to the predetermined pattern, the laser beam passing through the transparent member to contact and ablate the opaque layer and provide a clear image through the transparent member corresponding to the predetermined pattern.

Abstract: Provided are compounds having the formula: ##STR1## wherein: R.sup.1 and R.sup.2 are independently selected from the group consisting of a hydrogen atom, an aliphatic group, a hetero-aliphatic group, an aromatic group, and a heterocyclic group, provided that R.sup.1 and R.sup.2 may together form a divalent radical selected from the group consisting of an aliphatic radical and hetero-aliphatic group;each R.sup.3 is independently selected from the group consisting of an aliphatic group, a hetero-aliphatic group, an aromatic group, and a heterocyclic group;R.sup.4 is selected from the group consisting of an aliphatic group, a hetero-aliphatic group, an aromatic group, and a heterocyclic group; andn is an integer from 0 to 5.Also provided are polymerizable compositions containing such compounds and a method of coating a substrate which uses such polymerizable compositions.