Abstract: Described herein are high yield methods for making magnolol derivatives, together with novel intermediates and uses thereof.

Abstract: The invention provides antibacterial combinations of essential oils comprising bisabolol and one or more essential oils selected from citral, carvacrol, oregano extract, and rosemary, or comprising carvacrol and one or more essential oils selected from bisabolol, thymol, and rosemary, together with compositions, e.g., oral care compositions, comprising these combinations, and uses therefore.

Abstract: Procedures are provided to evaluate the effectiveness of slow-acting antibacterial agents such as metal salts on reduction of bacterial oral biofilm. In the modified process, the exposure time of the agent is increased from the usual 3 minutes to 7-15 minutes, e.g., about 10 minutes, and the duration increased to 5-12 days, e.g., about 8 days instead of the conventional 3 days.

Abstract: Surface staining can be minimized or eliminated by providing an oral care composition comprising a first film comprising a pigment; and optionally a second film; wherein the first film has a dissolution rate in aqueous media that is inversely proportional to its thickness, wherein the first film is in the form of a particle.

Abstract: Disclosed herein are orally acceptable topical analgesic gels comprising a mixture of analgesic oils comprising (a) clove oil and/or eugenol, (b) a cooling agent, and (c) camphor; in an orally acceptable gel base, the gel base providing controlled release of the mixture of analgesic oils following application to a tooth; together with methods of making and using the same.

Abstract: The present application provides a tooth anatomy model comprising: a first layer representing tooth dentin, said first layer being made of a first material; and a sensor system associated with a surface of the first layer, which system is adapted to sense at least one of temperature and air pressure. The present application also provides a method of demonstrating tooth hypersensitivity using a tooth anatomy model.

Abstract: Disclosed herein are orally acceptable topical analgesic gels comprising a mixture of analgesic oils comprising (a) clove oil and/or eugenol, (b) a cooling agent, and (c) camphor, in an orally acceptable gel base, the gel base comprising an anionic polymer and a basic amino acid, and the analgesic gel providing controlled release of the mixture of analgesic oils following application to a tooth together with a methods of making and using the same.

Abstract: Use of benzyl alcohol as a defoaming agent and an antimicrobial agent in an oral care composition including a surfactant. Also described is a method of manufacturing an oral care composition including forming an oral care base composition, subsequently combining the oral care base composition with a defoaming agent and at least one surfactant to form the oral care composition; and defoaming the oral care composition. The surfactant is combined with the oral care base composition no later than the defoaming agent. The defoaming agent is benzyl alcohol.

Abstract: The invention provides antibacterial combinations of essential oils comprising bisabolol and one or more essential oils selected from citral, carvacrol, oregano extract, and rosemary, or comprising carvacrol and one or more essential oils selected from bisabolol, thymol, and rosemary, together with compositions, e.g., oral care compositions, comprising these combinations, and uses therefore.

Abstract: Procedures are provided to evaluate the effectiveness of slow-acting antibacterial agents such as metal salts on reduction of bacterial oral biofilm. In the modified process, the exposure time of the agent is increased from the usual 3 minutes to 7-15 minutes, e.g., about 10 minutes, and the duration increased to 5-12 days, e.g., about 8 days instead of the conventional 3 days.

Abstract: Described herein are toothpastes comprising a first dentifrice comprising a calcium carbonate abrasive and a second dentifrice comprising a zinc ion source in a gel base, wherein the second dentifrice is entrained as a stripe in the first dentifrice, as well as products comprising the toothpaste and methods of making and using the same.

Abstract: Described herein are high yield methods for making magnolol derivatives, together with novel intermediates and uses thereof.

Abstract: Disclosed herein are orally acceptable topical analgesic gels comprising a mixture of analgesic oils comprising (a) clove oil and/or eugenol, (b) a cooling agent, and (c) camphor; in an orally acceptable gel base, the gel base providing controlled release of the mixture of analgesic oils following application to a tooth; together with methods of making and using the same.

Abstract: A composition of matter comprising an oil adduct synthesized by an oil and an addition material, wherein the oil includes at least one member chosen from an ethoxylated oil, a hydrogenated oil, and an ethoxylated and hydrogenated oil: wherein the average degree of ethoxylation in the ethoxylated (optionally hydrogenated) oil is less than about 10 based on moles of ethylene oxide per mole of oil: wherein the hydrogenated (optionally ethoxylated) oil has an iodine value of less than about 75: wherein the oil is capable of undergoing reaction with the addition material through a hydroxyl group of tile oil; and wherein the addition material includes at least one member chosen from carboxylic acid anhydrides, maleic anhydride, dicarboxylic acids, fumaric acid, maleic acid, succinic acids alpha hydroxy acids, beta hydroxy acids, lactic acid, glycolic acid, lactobionic acid, carnitine, salicylic acid, and (meth)acrylic acid.