Abstract: Disclosed are a polyethylene glycol conjugate drug, and a preparation method therefor and the use thereof. Specifically, the present invention relates to a polyethylene glycol conjugate drug represented by formula A or a pharmaceutically acceptable salt thereof, a method for preparing the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, an intermediate for preparing the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, a pharmaceutical composition comprising the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof, and the use of the polyethylene glycol conjugate drug or the pharmaceutically acceptable salt thereof in the preparation of a drug.

Abstract: A radio frequency (RF) match assembly for a chemical vapor deposition processing chamber. The assembly includes a top electrically insulating column and a bottom electrically insulating column. The assembly further includes a one-piece RF match strap that has a head, a main body and a body extension. The main body of the one-piece RF match strap is configured to extend through the top electrically insulating column and the bottom electrically insulating column. A flexible chamber lid strap connects the processing chamber to the top of the one piece RF match strap.

Abstract: A plunger pump base and a plunger pump device. The plunger pump base includes a support assembly and an extension assembly. The support assembly includes a top plate, a bottom plate and a support frame, the top plate and the bottom plate are oppositely arranged at an interval, and the support frame is respectively fixed with the top plate and the bottom plate. The extension assembly includes an extension block, a first telescopic mechanism and a second telescopic mechanism. One end of the first telescopic mechanism is rotatably connected to the extension block, the other end of the first telescopic mechanism is rotatably connected to the top plate. One end of the second telescopic mechanism is rotatably connected to the extension block, and the other end of the second telescopic mechanism is rotatably connected to the bottom plate.

Abstract: An integrated circuit includes first and second trenches in a semiconductor substrate and a semiconductor mesa between the first and second trenches. A source region having a first conductivity type and a body region having an opposite second conductivity type are located within the semiconductor mesa. A trench shield is located within the first trench, and a gate electrode is over the trench shield between first and second sidewalls of the first trench. A gate dielectric is on a sidewall of the first trench between the gate electrode and the body region, and a pre-metal dielectric (PMD) layer is over the gate electrode. A gate contact through the PMD layer touches the gate electrode between the first and second sidewalls, and a trench shield contact through the PMD layer touches the trench shield between the first and second sidewalls.

Abstract: Computer technology for retrieving data stored in a table that includes the following computer operations: receiving, from persistent storage of a computer, an original Index Tree data structure; storing, in volatile memory, a memory-based Index Tree data structure based on the original Index Tree data structure, with the memory-based Index Tree data structure including: a root node, a set of hierarchically arranged intermediate layer(s) with each intermediate layer including a plurality of non-leaf nodes, and a leaf layer including a plurality of leaf nodes; and retrieving data from a table in a database, with the retrieval including traversing the memory-based Index Tree data structure through a plurality of child lock pointers to locate pages including the data to be retrieved from the table.

Abstract: A method of wireless signal transmission management includes transmitting a plurality of data packets to tethering equipment from user equipment to tethering equipment, determining a size of each of the plurality of data packets by the tethering equipment, designating data packets of the plurality of data packets having a specific range of sizes as control signal packets by the tethering equipment, and prioritizing in transmitting the control signal packets to a cellular network by the tethering equipment.

Abstract: A method for manufacturing a semiconductor device is described. The method includes the following steps. A low-dimensional material (LDM) layer is formed on a semiconductor substrate, wherein the LDM layer includes sublayers stacked upon one another. A plasma treatment is performed to the LDM layer to transform at least one sublayer into an oxide layer, wherein the plasma treatment is performed under a temperature equivalent to or lower than about 80 degrees Celsius. At least one electrode is disposed over the oxide layer.

Abstract: A semiconductor structure includes a first metal-dielectric-metal layer, a first dielectric layer, a first conductive layer, a second conductive layer, and a second dielectric layer. The first metal-dielectric-metal layer includes a plurality of first fingers, a plurality of second fingers, and a first dielectric material. The first fingers are electrically connected to a first voltage. The second fingers are electrically connected to a second voltage different from the first voltage, and the first fingers and the second fingers are arranged in parallel and staggeredly. The first dielectric material is between the first fingers and the second fingers. The first dielectric layer is over the first metal-dielectric-metal layer. The first conductive layer is over the first dielectric layer. The second conductive layer is over the first conductive layer. The second dielectric layer is between the first conductive layer and the second conductive layer.

Abstract: A computer-implemented method that includes receiving an ingestion request to ingest data to a database comprising physical shards and detecting that the ingestion request is directed to a first hotspot shard. The first hotspot shard has a contention level over a threshold value. The method also detects context characteristics within the data and generates a first virtual shard based on a first virtual shard key selected from the detected context characteristics. The first virtual shard virtually duplicates at least a portion of the first hotspot shard. The method also includes ingesting the data to the first virtual shard.

Abstract: This disclosure provides a computer-implemented method, a computer system and a computer program product for database compression oriented to combinations of fields of a database record. One or more combinations of fields of a record of a database are determined that satisfy a frequency criterion indicating that access frequencies of the one or more combinations of fields are higher than an access frequency threshold. The record is reorganized based on the one or more combinations of fields to store fields of each combination of the one or more combinations of fields in a respective contiguous storage space. The reorganized record is compressed by applying a compression scheme to the one or more combinations of fields.

Abstract: A flexible container (10) is disclosed. The flexible container (10) includes four panels (18, 20, 22, 24), each panel comprising a flexible multilayer film. Each flexible multilayer film is composed of a polymeric material. The four panels form (i) a body, (ii) a neck, and (iii) a handle. The handle (12) has an upper handle portion (12a) and a pair of spaced-apart legs (13, 15). The legs extend from the upper handle portion to the body on opposing sides of the neck. The flexible container includes a fitment (70) sealed to the neck. The flexible container includes a dispensing pump (100) attached to the fitment. The flexible container can provide a metered dose from a dispensing pump and the dispensing pump can also function as a handle to hand-carry the flexible container.

Abstract: The present invention discloses a semi-trailer-loaded turbine fracturing equipment, which adopts a linear connection of the whole equipment and a special chassis design, so that the center of gravity is double lowered to guarantee its stability and safety, the structure is simpler, the investment and operation costs are decreased, the risk of total breakdown of the fracturing site is reduced, and the equipment has a good transmission performance and is suitable for continuous operation conditions with long time and heavy load.

Abstract: This application discloses electromagnetic energy mitigation assemblies and automotive vehicle components comprising the electromagnetic energy mitigation assemblies. An electromagnetic energy mitigation assembly includes a first electrically conductive layer and a second electrically conductive layer. First and second permalloy layers are along respective first and second opposite sides of the first electrically conductive layer. Third and fourth permalloy layers are along respective third and fourth opposite sides of the second electrically conductive layer. An electromagnetic noise suppression layer is sandwiched between the second and third permalloy layers. An automotive vehicle component includes an electromagnetic energy mitigation assembly configured to be positioned relative to one or more batteries of an automotive vehicle for providing electromagnetic shielding for the one or more batteries. The electromagnetic energy mitigation assembly includes a first electrically conductive layer.

Abstract: A high-performance thermal interface comprising a nanowire array disposed between a bottom metal layer and a top metal layer in which each nanowire is coated with a 3D fuzzy graphene layer. The thermal interface can be used by bonding it to the surfaces of adjoining substrates using layers of solder.

Abstract: Provided are Enterococcus lactis, a drug for preventing or treating tumor, and use thereof, relating to the technical field of biomedicines. Novel Enterococcus lactis is separated and chosen, and the Enterococcus lactis has an important influence on the effect of tumor immunotherapy for cancer patients. Gut microorganisms and immune cells can interact with each other to jointly regulate the human immune system. The provided Enterococcus lactis can induce the differentiation and maturation of iDC (immature DC) cells, and mature DC can effectively activate T cells and increase the infiltration of tumor infiltrating lymphocytes having anti-tumor activity, thereby killing tumor cells. In addition, the provided Enterococcus lactis can induce the differentiation of M0 type macrophages into M1 or M2 type cells.

Abstract: Various embodiments of the present application are directed towards a control gate layout to improve an etch process window for word lines. In some embodiments, an integrated chip comprises a memory array, an erase gate, a word line, and a control gate. The memory array comprises a plurality of cells in a plurality of rows and a plurality of columns. The erase gate and the word line are elongated in parallel along a row of the memory array. The control gate is elongated along the row and is between and borders the erase gate and the word line. Further, the control gate has a pad region protruding towards the erase gate and the word line. Because the pad region protrudes towards the erase gate and the word line, a width of the pad region is spread between word-line and erase-gate sides of the control gate.

Abstract: The present disclosure relates to a thermoplastic pulverulent composition comprising (a) at least one silica particle treated with alkoxysilane; and (b) at least one thermoplastic polymer. The present disclosure also relates to a 3D-printed object formed from the thermoplastic pulverulent composition and a process of forming the 3D-printed object. The thermoplastic pulverulent composition shows good powder flowability and the printed object obtained from said thermoplastic pulverulent composition surprisingly shows high elongation at break, high impact strength, good toughness and low surface roughness.

Abstract: A method may include forming a mask layer on top of a first dielectric layer formed on a first source/drain and a second source/drain, and creating an opening in the mask layer and the first dielectric layer that exposes portions of the first source/drain and the second source/drain. The method may include filling the opening with a metal layer that covers the exposed portions of the first source/drain and the second source/drain, and forming a gap in the metal layer to create a first metal contact and a second metal contact. The first metal contact may electrically couple to the first source/drain and the second metal contact may electrically couple to the second source/drain. The gap may separate the first metal contact from the second metal contact by less than nineteen nanometers.

Abstract: In response to receiving a request for an identity key from a first entity, an identity key for the first entity is generated. A first request from the first entity to replicate a set of data is received. The generated identity key for the first entity is added to the metadata of the set of data requested to be replicated. A determination is made whether a replication rule exists for the first entity. In response to determining that a replication rule exists for the first entity, the set of data is replicated according to the replication rule for the first entity.

Abstract: Various examples are provided related to phosphosite prediction. In one example, a system includes a computing device and an application for phosphosite prediction stored in memory. When executed, the application can cause the computing device to transform a protein sequence to a context-aware protein sequence by a Phosformer based transformer. The transformation can include predicting phosphorylation associations from the protein sequence based upon a trained Phosformer model and generating the context-aware protein sequence based upon the predicted phosphorylation associations, the context-aware protein sequence including a predicted phosphosite. The predicted phosphosite can be rendered for presentation to a user.