Abstract: The invention provides nucleic acid molecules encoding FGF21 mutant polypeptides, FGF21 mutant polypeptides, pharmaceutical compositions comprising FGF21 mutant polypeptides, and methods for treating metabolic disorders using such nucleic acids, polypeptides, or pharmaceutical compositions.

Abstract: A setting method of in-memory computing simulator includes: performing a plurality of test combinations by an in-memory computing device and recording a plurality of first estimation indices corresponding to the plurality of test combinations respectively, wherein each of the plurality of test combinations includes one of a plurality of neural network models and one of a plurality of datasets, executing a simulator according to the plurality of test combinations by a processing device and recording a plurality of second estimation indices corresponding to the plurality of test combinations respectively, wherein the simulator has a plurality of adjustable settings; calculating a correlation sum according to the plurality of first estimation indices and the plurality of second estimation indices by the processing device, and performing an optimal algorithm to search an optimal parameter in the setting space constructed by the plurality of settings so that the correlation sum is maximal.

Abstract: Microelectronic assemblies, related devices and methods, are disclosed herein. In some embodiments, a microelectronic assembly may include a conductive pad having a first surface, an opposing second surface, and lateral surfaces extending between the first and second surfaces; a conductive via coupled to the first surface of the conductive pad; a liner on the second surface and on the lateral surfaces of the conductive pad, wherein a material of the liner includes nickel, palladium, or gold; a microelectronic component having a conductive contact; and an interconnect electrically coupling the conductive contact of the microelectronic component and the liner on the second surface of the conductive pad, wherein a material of the interconnect includes nickel or tin.

Abstract: A micro light-emitting diode display panel includes a substrate, at least one light-emitting element, a reflective layer and a light-absorbing layer. The at least one light-emitting element is disposed on the substrate to define at least one pixel, and each light-emitting element includes micro light-emitting diodes. The reflective layer is disposed on the substrate and located between the micro light-emitting diodes. The reflective layer has cavities surrounding the micro light-emitting diodes, such that a thickness of a portion of the reflective layer close to any one of the micro light-emitting diodes is greater than a thickness of a portion of the reflective layer away from the corresponding micro light-emitting diode. The light-absorbing layer is at least disposed in the cavities of the reflective layer.

Abstract: A process for producing a barrier composition includes subjecting a siloxane compound having 1 to 3 amino groups and an aqueous solution including water and an alcohol to hydrolysis and first-stage condensation under required conditions, subjecting a first colloidal mixture obtained and an additional alcohol to second-stage condensation, subjecting a second colloidal mixture obtained, which has a particular solid content, to heating under required conditions, and subjecting a cured product obtained to aging under required conditions. A barrier composition produced by the process is also disclosed.

Abstract: Aspects of the present disclosure provide a method for training a predictor that predicts performance of a plurality of machine learning (ML) models on platforms. For example, the method can include converting each of the ML models into a plurality of instructions or the instructions and a plurality of intermediate representations (IRs). The method can also include simulating execution of the instructions corresponding to each of the ML models on a platform and generating instruction performance reports. Each of the instruction performance reports can be associated with performance of the instructions corresponding to one of the ML models that are executed on the platform. The method can also include training the predictor with the instructions or the IRs as learning features and the instruction performance reports as learning labels, compiling the predictor into a library file, and storing the library file in a storage device.

Abstract: Disclosed are techniques for relational database locks based on columns. Database transactions may be targeted to specific columns of one or more records, instead of the entire row for those records, using primary keys. Column locks on specific keys are stored separately than column locks on ranges of keys, which are both checked when requesting a new column lock for either a single key or a range of keys. When a threshold number of columns for a given record, or range of records/keys, have been locked, the column locks for that record, or range of records, can be combined into a single row level lock to reduce resource costs for maintaining multiple concurrent locks.

Abstract: The present invention relates to polypeptides which share primary sequence with human IL-2, except for several amino acids that have been mutated. One panel of IL-2 variants comprise mutations with impressive manufacturability that preferentially promotes the proliferation, survival, activation and/or function of immunosuppressive regulatory T cells (Treg: CD4+CD25+FoxP3+) over effector T cells and NK cells. Also includes therapeutic uses of such IL-2 selective agent, used alone, or in combination with immune modulating agents or disease-tissue targeting antibody, protein or peptide to treat Treg cell-deficiency, various autoimmune and inflammatory disorders, organ transplantation and graft-versus-host disease. In another aspect the present invention relates to pharmaceutical compositions comprising the polypeptides disclosed.

Abstract: A digital image processor includes a region proposal network configured to transform digital image inputs into region proposals and bounding box refinement logic configured to transform the region proposals by determining a first set of the region proposals exhibiting dense spacing, determining a second set of the region proposals exhibiting sparse spacing, executing a first transformation to merge at least some of the region proposals exhibiting dense spacing to generate refined region proposals, executing a second transformation to join at least some of the region proposals exhibiting sparse spacing to generate additional ones of the refined region proposals, and applying an expansion transformation to the refined region proposals.

Abstract: A microelectronic device is formed to include an embedded die substrate on an interposer; where the embedded die substrate is formed with no more than a single layer of transverse routing traces. In the device, all additional routing may be allocated to the interposer to which the embedded die substrate is attached. The embedded die substrate may be formed with a planarized dielectric formed over an initial metallization layer supporting the embedded die.

Abstract: An electronic device, which comprises a memory, a processor, and a serial number length adjustment program stored in the memory and operable on the processor is disclosed. The serial number length adjustment program is executed by the processor to implement following functions: performing an angle estimation algorithm on all user equipments (UEs) through a low-frequency band to estimate beam angles of the UEs relative to the electronic device; generating high-frequency band beams of the UEs relative to the electronic device according to the estimated beam angles; and enabling the electronic device to communicate with the UEs according to the generated high-frequency band beams.

Abstract: Aspects of the disclosure are directed to jointly searching machine learning model architectures and hardware architectures in a combined space of models, hardware, and mapping strategies. A search strategy is utilized where all models, hardware, and mappings are evaluated together at once via weight sharing and a supernetwork. A multi-objective reward function is utilized with objectives for quality, performance, power, and area.

Abstract: Disclosed is tuning and matching devices and methods, magnetic resonance imaging (MRI) equipment, and display interaction devices. The MRI equipment may include a transmitting coil. The tuning and matching control device may be connected with the transmitting coil and configured to perform tuning and matching on the transmitting coil. The display interaction device may be in a scanning room. The tuning and matching method may include: first obtaining curve information of a tuning curve, if determining that the curve information of the tuning curve to be displayed is not within a set information range, adjusting layout information of the tuning curve to be displayed in a display interface, and displaying the adjusted tuning curve in the display interface.

Abstract: A beam tracking method for mmWave communication method is disclosed. An angle estimation algorithm is performed on all user equipments (UEs) through a low-frequency band to estimate beam angles of the UEs relative to the electronic device. High-frequency band beams of the UEs relative to the electronic device are generated according to the estimated beam angles. The electronic device is enabled to communicate with the UEs according to the generated high-frequency band beams.

Abstract: A rocking arm structure includes an arm body, a first wheel assembly connected to the arm body, a second wheel assembly connected to the arm body, and a shaft assembly disposed between the first wheel assembly and the second wheel assembly. The arm body can rotate relative to the main body around the shaft assembly, and drive the first wheel assembly and the second wheel assembly to revolve in a same direction around the shaft assembly. The first wheel assembly and the second wheel assembly are both steering wheel assemblies or both directional wheel assemblies.

Abstract: Embodiments of this application provide an application starting method and apparatus, and an electronic device. For any application that is installed in the electronic device and that supports multi-window display, based on configurations of an application layer and an application framework layer in a software system of the electronic device, the electronic device that supports a floating window and split-screen display may have a single-application multi-instance feature. In this way, the Dock triggers any application to start the multi-instance feature of the application, and the electronic device may simultaneously display a plurality of windows of the application on a display in a plurality of window combination forms, so that multi-instance coordination processing and operation may be performed on a same application.

Abstract: A display screen cover is arranged to correspond to an area array driving plate of a display screen, and the display screen cover includes a cover body and a polarization film assembly. The polarization film assembly is arranged on the back of the cover body, and the polarization film assembly is provided with polarization film through holes and polarization film sound transmission spaces. The polarization film through holes are arranged to correspond to light-emitting tubes of the area array driving plate, and the polarization film sound transmission spaces are arranged to correspond to sound transmission spaces of the area array driving plate. The cover body is provided with cover through holes and cover sound transmission spaces. The cover through holes are arranged to correspond to the polarization film through holes, and the cover sound transmission spaces are arranged to correspond to the polarization film sound transmission spaces.

Abstract: A beam tracking method for mmWave communication method is disclosed. An angle estimation algorithm is performed on all user equipments (UEs) through a low-frequency band to estimate beam angles of the UEs relative to the electronic device. High-frequency band beams of the UEs relative to the electronic device are generated according to the estimated beam angles. The electronic device is enabled to communicate with the UEs according to the generated high-frequency band beams.

Abstract: A method may include forming a mask layer on top of a first dielectric layer formed on a first source/drain and a second source/drain, and creating an opening in the mask layer and the first dielectric layer that exposes portions of the first source/drain and the second source/drain. The method may include filling the opening with a metal layer that covers the exposed portions of the first source/drain and the second source/drain, and forming a gap in the metal layer to create a first metal contact and a second metal contact. The first metal contact may electrically couple to the first source/drain and the second metal contact may electrically couple to the second source/drain. The gap may separate the first metal contact from the second metal contact by less than nineteen nanometers.

Abstract: The invention provides nucleic acid molecules encoding FGF21 mutant polypeptides, FGF21 mutant polypeptides, pharmaceutical compositions comprising FGF21 mutant polypeptides, and methods for treating metabolic disorders using such nucleic acids, polypeptides, or pharmaceutical compositions.