Abstract: An intelligent pressure-sensitive adjustable bedding and a manufacturing method thereof are provided. The bedding includes an inner pad, an inflation/deflation assembly, and a fixing base, wherein the inner pad and the inflation/deflation assembly are connected to each other and both are arranged in the fixing base; the inner pad is formed with a plurality of first clamping grooves and a plurality of second clamping grooves; the second clamping grooves are symmetrically distributed on both sides of the first clamping grooves; the first clamping grooves are provided with first airbags; the second clamping grooves are provided with second airbags; and both the first airbags and the second airbags are connected to the inflation/deflation assembly; the inner pad includes a latex core and a waterproof and flame-retardant cover, wherein the waterproof and flame-retardant cover wraps around the outside of the latex core, and the latex core is made of an antibacterial material.

Abstract: Provided are a nanoscale geometrical quantity certified reference material, and a preparation method and use thereof, belonging to the technical field of nano-scale measurements. The nanoscale geometrical quantity certified reference material includes a substrate and a periodic nanostructured two-dimensional supramolecular film attached to the substrate, where the periodic nanostructured two-dimensional supramolecular film is formed by self-assembly of 5,5?-(9H-fluorene-2,7-diyl)diisophthalic acid and 1,2-bis(4-pyridyl)ethane. Provided is also a preparation method of the nanoscale geometrical quantity certified reference material. The self-assembly is a bottom-up process to prepare a periodic nanostructured two-dimensional supramolecular film.

Abstract: A method for determining a current sensor offset of a current sensor (47) in a device battery (41) of a technical device (4). In one example, the method includes measuring the battery current using the current sensor (47); providing (S1) a temporal profile of the battery current; recording (S2) a charge balance of the electrical charge amount flowing into the device battery (41) and out of the device battery (41) over time depending on the temporal profile of the battery current; creating (S2) or adjusting a charge balance model depending on a time-accumulated charge amount; and determining the current sensor offset depending on a local slope of the charge balance model at a specified time.

Abstract: A matrix decomposition structure of a two-channel quadrature mirror filter bank, including an analysis filter part, a synthesis filter part, the filter part includes an E0,M module, an X module, a Y module, a Z module, an input port and an output port. The X module takes a value of the input port as an input of a multiplier, and the E0,M module delays the input. An output of the Xmodule passes through the Y module and then is used as an input of the Z module, and outputs of the Z module and the E0,M module are added and then output from the output port, and pass through a middle part to enter the synthesis filter part.

Abstract: Disclosed are a water-soluble fluorescent probe and nanoparticles with an aggregation induced emission (AIE) effect and preparation methods and the application. The fluorescent probe molecule includes one imidazole ring substituted by two methoxyphenyls and one phenyl and two quaternary ammonium salt structures. It has good dispersion in water, may form micelles. It has the characteristics of AIE effect and a large Stokes shift etc. It is suitable for fluorescence detection. Under the induction of lysophosphatidic acid, the probe can be self-assembled so as to aggregate and generate yellow fluorescence. Lysophosphatidic acid may be quantitatively analyzed by measuring the intensity of emitted fluorescence.

Abstract: The present invention relates to methods, uses, and compositions for the treatment of cancer (e.g., a lung cancer; a cervical cancer; a breast cancer; a head and neck cancer; a liver cancer; a bladder cancer; a gastric cancer; an esophageal cancer; a pancreatic cancer; a kidney or renal cancer; a melanoma; an ovarian cancer; or a colorectal cancer). More specifically, the invention concerns the treatment of patients having cancer with an anti-TIGIT antagonist antibody, including treatment with an anti-TIGIT antagonist antibody in a combination therapy.

Abstract: A shader auto-simplifying method and system include: obtaining a rendering instruction flow, extracting a target shader from the rendering instruction flow, and creating a simplifying shader differing from the target shader in code only; intercepting a current frame of a rendering instruction with a rendering initiating instruction of the target shader as a particular frame; obtaining time consumed by the simplifying shader by measuring time needed for rendering the particular frame with the simplifying shader; obtaining error(s) of the simplifying shader by measuring a pixel difference value between a rendering frame drawn by the simplifying shader and the particular frame when a rendering instruction corresponding to the particular frame is executed; and screening an optimal simplifying shader according to the time consumed by the simplifying shader and the error of the simplifying shader.

Abstract: A membrane for selective separation of a target cation from a source liquid containing the target cation and one or more competing ionic species can include a crown ether polymer layer disposed on a cation exchange membrane. The crown ether polymer layer can include a crown ether capable of selectively binding the target cation and a polymer.

Abstract: A method for determining a current sensor offset of a current sensor (47) in a device battery (41) of a technical device (4). In one example, the method includes measuring the battery current using the current sensor (47); providing (S1) a temporal profile of the battery current; recording (S2) a charge balance of the electrical charge amount flowing into the device battery (41) and out of the device battery (41) over time depending on the temporal profile of the battery current; creating (S2) or adjusting a charge balance model depending on a time-accumulated charge amount; and determining the current sensor offset depending on a local slope of the charge balance model at a specified time.

Abstract: A method for predicting an aging state of a device battery with at least one electrochemical unit includes providing a temporal operating variable profile of an operating variable of a device battery, determining successive cycles from the temporal operating variable profile, respectively assigning the determined cycles to predetermined cycle profiles so that a sequence of cycle profiles is obtained, determining a frequency distribution of transitions in the obtained sequence of cycle profiles in the form of a hidden Markov model, creating a predicted sequence of cycle profiles by successively, randomly selecting cycle profiles according to the frequency distribution of the transitions, assigning profile operating variable profiles assigned to the cycle profiles to the predicted sequence of cycle profiles to obtain a predicted operating variable profile, and determining a predicted aging state or a predicted aging state profile based on the predicted operating variable profile using a predetermined aging stat

Abstract: The present invention discloses a shader auto-simplifying method and system based on a rendering instruction flow, the method including: obtaining a rendering instruction flow, extracting a target shader from the rendering instruction flow, and creating a simplifying shader differing from the target shader in code only; intercepting a current frame of a rendering instruction comprising a rendering initiating instruction of the target shader as a particular frame; obtaining time consumed by the simplifying shader by measuring time needed for rendering the particular frame with the simplifying shader; obtaining error(s) of the simplifying shader by measuring a pixel difference value between a rendering frame drawn by the simplifying shader and the particular frame when a rendering instruction corresponding to the particular frame is executed; and screening an optimal simplifying shader according to the time consumed by the simplifying shader and the error of the simplifying shader.

Abstract: The embodiments of the present disclosure disclose an ultrasonic microbubble generation method, apparatus and system. The apparatus comprises a horn-shaped conductor including an upper horn-shaped body and a lower cylindrical body; the horn-shaped body is provided with a cavity having an upper opening, an upper end of the cavity is fixedly connected with a micropore vibration thin sheet, a micropore array of the micropore vibration thin sheet is corresponding to the upper opening of the cavity, and a side wall of the cavity is provided with a through hole for external gas to enter the cavity; the cylindrical body is provided with a transducing ring and an electrode sheet, an outer side of the cylindrical body is insulated and sealed, and a connection wire of the electrode sheet is led out by a steel pipe and connected with an external ultrasonic oscillation controller.

Abstract: The present disclosure provides a tip-enhanced Raman spectroscope system. The system includes a laser emitting unit, a laser excitation unit, a first dichroic beam splitter, a first Raman spectrometer, and a confocal detecting unit. The laser excitation unit includes a sample stage and a first scanning probe. The sample stage is configured to have a sample disposed thereon such that a first incident laser beam emitted from the laser emitting unit is transmitted to the sample to excite first scattered light. The first dichroic beam splitter is configured to split a first Raman scattered light from the first Rayleigh scattered light. The first Raman spectrometer is disposed on a first Raman optical path of the first Raman scattered light. The confocal detecting unit is disposed on a first Rayleigh optical path of the first Rayleigh scattered light to image the sample.

Abstract: The present invention relates to methods, uses, and compositions for the treatment of cancer (e.g., a lung cancer; a cervical cancer; a breast cancer; a head and neck cancer; a liver cancer; a bladder cancer; a gastric cancer; an esophageal cancer; a pancreatic cancer; a kidney or renal cancer; a melanoma; an ovarian cancer; or a colorectal cancer). More specifically, the invention concerns the treatment of patients having cancer with an anti-TIGIT antagonist antibody, including treatment with an anti-TIGIT antagonist antibody in a combination therapy.

Abstract: The present invention relates to the treatment of esophageal cancer, e.g., esophageal squamous cell carcinoma (ESCC) (e.g., advanced ESCC (e.g., unresectable, locally advanced, recurrent, and/or metastatic ESCC)). More specifically, the invention pertains to the treatment of patients having esophageal cancer by administering a combination of an anti-T-cell immunoreceptor with Ig and ITIM domains (TIGIT) antagonist antibody and a programmed death-1 (PD-1) axis binding antagonist.

Abstract: The present disclosure provides a microbubble generation device and equipment, wherein the microbubble generation device comprises: a microbubble generation mechanism having a housing and a core tube provided to pass therethrough, wherein at least one filter plate is provided on a peripheral sidewall of the housing, and an annular space is formed between the housing and the core tube; a flow rate control mechanism provided in the annular space, and connected to the core tube that is communicated with the annular space through the flow rate control mechanism, wherein a blocking ball is provided in the flow rate control mechanism and capable of blocking the flow rate control mechanism in a state that a pressure of gas injected into the flow rate control mechanism decreases; and a pressure balancing mechanism provided outside the housing and having a pressure balancing tube and a fluid check valve connected thereto.

Abstract: Disclosed are a water-soluble fluorescent probe and nanoparticles with an aggregation induced emission (AIE) effect and preparation methods and the application. The fluorescent probe molecule includes one imidazole ring substituted by two methoxyphenyls and one phenyl and two quaternary ammonium salt structures. It has good dispersion in water, may form micelles. It has the characteristics of AIE effect and a large Stokes shift etc. It is suitable for fluorescence detection. Under the induction of lysophosphatidic acid, the probe can be self-assembled so as to aggregate and generate yellow fluorescence. Lysophosphatidic acid may be quantitatively analyzed by measuring the intensity of emitted fluorescence.

Abstract: A system and method of performing oil displacement by a water-gas dispersion system includes a micro-bubble generation apparatus, a gas source, an ultrasonic oscillation controller, a protective barrel and a support. A first opening is provided in a top end of the protective barrel, into which an internal apparatus enters and is extracted, the first opening is sealed by an end cover. A second opening communicating with a water flooding pipeline is provided in a side wall of the protective barrel, into which fluid flows and from which the fluid exits. The micro-bubble generation apparatus is fixed within the protective barrel by the support. The gas source is connected with the micro-bubble generation apparatus through a gas pipeline, for transporting gas to the micro-bubble generation apparatus. The ultrasonic oscillation controller is connected to the micro-bubble generation apparatus through a signal line, for controlling the micro-bubble generation apparatus to generate micro-bubbles.

Abstract: An image fusion-guidance device based on respiratory gating and CT includes a CT scanner, which is provided with a respiratory gating device and a gantry. A patient couch and a treatment head are provided in the gantry. A respiratory gating sensor is provided on the patient couch. The respiratory gating device is connected to a CT image workstation and an image fusion acquisition device via synchronization signal lines. The image fusion acquisition device is connected to an image fusion-processing device, which is connected to an image fusion display device. The treatment head is connected to a beam output controller via a beam output control line. The present application further provides an image fusion-guidance method based on respiratory gating and CT. In the guiding process, the patient is only required to hold the breath once, and then the patient breathes freely in the subsequent treatment.