Abstract: The present invention provides an interspecific Helianthus plant comprising a genetic determinant responsible for an indeterminate phenotype. Methods of making said plant are also provided.

Abstract: Disclosed herein are novel compounds of formula (I) as described herein: and the use of such peptides in making immunoconjugates (i.e Antibody Drug Conjugates) Also described herein are immunoconjugates (i.e Antibody Drug Conjugates) comprising such novel compound linked to an antigen binding moiety, such as an antibody; where such immunoconjugates are useful for treating cell proliferative disorders. The invention further provides pharmaceutical compositions comprising these immunoconjugates, compositions comprising the immunoconjugates with a therapeutic co-agent, and methods to use these immunoconjugates and compositions for treating cell proliferation disorders.

Abstract: Disclosed herein are novel compounds of formula (I) as described herein: and the use of such peptides in making immunoconjugates (i.e Antibody Drug Conjugates) Also described herein are immunoconjugates (i.e Antibody Drug Conjugates) comprising such novel compound linked to an antigen binding moiety, such as an antibody; where such immunoconjugates are useful for treating cell proliferative disorders. The invention further provides pharmaceutical compositions comprising these immunoconjugates, compositions comprising the immunoconjugates with a therapeutic co-agent, and methods to use these immunoconjugates and compositions for treating cell proliferation disorders.

Abstract: The present invention relates to methods for modulating the Wnt signaling pathway using compounds of Formula (1), wherein A1, Y and Z all represent rings.

Abstract: A new Lantana plant named ‘LANZ0013’ particularly distinguished by the large sized tri-colored, golden, orange and scarlet red flowers, excellent floriferousness, and dense mounding habit with medium green foliage.

Abstract: The present invention relates to compounds and compositions for expanding the number of CD34+ cells for transplantation. The invention further relates to a cell population comprising expanded hematopoietic stem cells (HSCs) and its use in autologous or allogeneic transplantation for the treatment of patients with inherited immunodeficient and autoimmune diseases and diverse hematopoietic disorders to reconstitute the hematopoietic cell lineages and immune system defense.

Abstract: Disclosed herein are novel compounds of formula (I) as described herein: and the use of such peptides in making immunoconjugates (i.e Antibody Drug Conjugates) Also described herein are immunoconjugates (i.e Antibody Drug Conjugates) comprising such novel compound linked to an antigen binding moiety, such as an antibody; where such immunoconjugates are useful for treating cell proliferative disorders. The invention further provides pharmaceutical compositions comprising these immunoconjugates, compositions comprising the immunoconjugates with a therapeutic co-agent, and methods to use these immunoconjugates and compositions for treating cell proliferation disorders.

Abstract: The present invention relates to compounds and compositions for expanding the number of CD34+ cells for transplantation. The invention further relates to a cell population comprising expanded hematopoietic stem cells (HSCs) and its use in autologous or allogeneic transplantation for the treatment of patients with inherited immunodeficient and autoimmune diseases and diverse hematopoietic disorders to reconstitute the hematopoietic cell lineages and immune system defense.

Abstract: A new Lantana plant named ‘LANZ0012’ particularly distinguished by uniform golden yellow flowers, large inflorescences, green foliage, and vigorous trailing but tight branching plant habit.

Abstract: The present invention relates to methods for modulating the Wnt signaling pathway using compounds of Formula (1), wherein A1, Y and Z all represent rings.

Abstract: The present invention relates to compositions and methods for modulating the Wnt signaling pathway.

Abstract: The invention provides a method, compounds and compositions for modulating the activity of the hedgehog signaling pathway. In particular, the invention provides a method for inhibiting aberrant growth states resulting from phenotypes such as Ptc loss-of-function, hedgehog gain-of-function, smoothened gain-of-function or Gli gain-of-function, comprising contacting a cell with a sufficient amount of a compound of Formula (I).

Abstract: The present invention relates to compositions and methods for modulating the Wnt signaling pathway, using compounds having Formula (1) and (3): wherein A, B, Y and Z all represent rings, and R1, R2, R3 are as defined herein.

Abstract: The invention provides a novel class of compounds of Formula (I) (wherein A, Y, R2, R3, R4 and R5 are defined in the summary of the invention), pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly diseases or disorders that involve abnormal activation of B-Raf.

Abstract: A new Lantana plant named ‘LANZ0009’ particularly distinguished by large size deep red and yellow flowers with free and early flowering, excellent inflorescences, down spreading plant habit and small size dark green foliage.

Abstract: A new Lantana plant named ‘LANZ0011’, particularly distinguished by small size yellow flowers, excellent floriferousness, medium-spreading bushy habit, dark green foliage and early flowering.

Abstract: A new Lantana plant named ‘LANZ0007’ particularly distinguished large sized golden yellow to orange flowers with an orange throat, dark green foliage, dense mounding habit, early flowering, excellent floriferousness, and good heat tolerance compared with control.

Abstract: A new Lantana plant named ‘LANZ0008’ particularly distinguished large sized, cream yellow to pink flowers with an yellow throat, dark green foliage, early flowering and excellent floriferousness, spreading plant habit and good heat tolerance compared to control.

Abstract: A new Lantana plant named ‘LANZ0013’ particularly distinguished by the large sized tri-colored, golden, orange and scarlet red flowers, excellent floriferousness, and dense mounding habit with medium green foliage.

Abstract: A new Lantana plant named ‘LANZ0012’ particularly distinguished by uniform golden yellow flowers, large inflorescences, green foliage, and vigorous trailing but tight branching plant habit.