Abstract: The present invention provides a compound exhibiting coronavirus 3 CL protease inhibitory activity or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same. Furthermore, the present invention provides a crystalline form useful as an active pharmaceutical ingredient, and a pharmaceutical composition comprising the same. A compound represented by Formula: or a pharmaceutically acceptable salt thereof.

Abstract: A wind power generator includes a vertical axis type wind power generation mechanism and a support mechanism. The wind power generation mechanism includes a wind collector, a windmill with a plurality of blades, a windmill rotation shaft, and a generator. The wind collector is formed to surround an outer circumference of the blades. The generator is directly connected to the windmill rotation shaft. The support mechanism includes a mount, and an attitude control means. The wind power generator installed in a stationary state enables to generate power, or the wind power generator fixedly installed on a moving body enables to generate power. The A rear end portion of a horizontal axis type wind power generation mechanism is detachably connected to a lower end portion of the vertical axis type wind power generation mechanism.

Abstract: The present invention provides a compound exhibiting coronavirus 3CL protease inhibitory activity or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same. Furthermore, the present invention provides a crystalline form useful as an active pharmaceutical ingredient, and a pharmaceutical composition comprising the same. A compound represented by Formula: , or a pharmaceutically acceptable salt thereof.

Abstract: The present invention provides a compound exhibiting coronavirus 3CL protease inhibitory activity or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the same. Furthermore, the present invention provides a crystalline form useful as an active pharmaceutical ingredient, and a pharmaceutical composition comprising the same. A compound represented by Formula (I): wherein Y is N or the like; R1 is substituted or unsubstituted aromatic heterocyclyl or the like; R2 is substituted or unsubstituted aromatic carbocyclyl or the like; R3 is substituted or unsubstituted aromatic heterocyclyl or the like; —X— is —NH— or the like; m is 1 or the like; R5a is each independently a hydrogen atom or the like; R5b is each independently a hydrogen atom or the like; n is 1 or the like; R4a is each independently a hydrogen atom or the like; and R4b is each independently a hydrogen atom or the like, or a pharmaceutically acceptable salt thereof.

Abstract: An image processing device includes a storage unit, an initial setting unit configured to store a position of an optical axis neighborhood point in a first image obtained by the imaging unit in the storage unit as an initial position of a specific point in the first image in association with image features of a surrounding area of the optical axis neighborhood point, a search unit configured to search for a corresponding point of the specific point in a second image obtained by the imaging unit based on the image features of the surrounding area of the specific point stored in the storage unit, and an output unit configured to output a position of the corresponding point in the second image as a position of the reference point in the second image.

Abstract: A vertical axial wind power generator including blades rotated in a horizontal direction, and each blade includes inner and outer wind collection vanes, so that the blades can be operated without being limited by space and environment and can be rotated vertically by tiny wind. When wind power is lower than magnetic force of magnet on the blades and fastening disks, the blades enters an open status to increase windward area; when wind power is higher than the magnetic force, centrifugal force can force the blade to close to become a ball type, and blades of the ball type can have strong torsion effect, and only the windward area of the outer wind collection vane receive wind, so that rotation speed of the wind power generator can be stable. When wind power becomes weak, the blades can be rotated reversely to the open status.

Abstract: An inspection system of an embodiment includes: a planar illumination unit that temporally and spatially varies intensities of light in a periodic manner; a time-correlation image generator that generates a time-correlation image with a time-correlation camera or an image capturing system that performs an operation equivalent to that of the time-correlation camera; and a calculation processor that calculates a characteristic from the time-correlation image, the characteristic corresponding to a distribution of normal vectors to an inspection target surface and serving to detect an abnormality based on at least either a difference from a surrounding area or a difference from a reference surface.

Abstract: The disclosure relates to Compounds of Formula (I) and pharmaceutically acceptable derivatives thereof, where R1, R4, R8, R9, and m are as defined herein, compositions comprising an effective amount of a Compound of Formula (I) or a pharmaceutically acceptable derivative thereof, and methods for treating or preventing a condition such as pain, pain associated with osteoarthritis, osteoarthritis, UI, an ulcer, IBD, and IBS, comprising administering to an animal in need thereof an effective amount of a Compound of Formula (I) or a pharmaceutically acceptable derivative thereof.

Abstract: An inspection system of an embodiment includes: a planar illumination unit that temporally varies an intensity of light in a periodic manner by spatially moving a stripe pattern of the intensity of light; a time-correlation image generator that generates a time-correlation image with a time-correlation camera or an image capturing system that performs an operation equivalent to that of the time-correlation camera; and a calculation processor that calculates a characteristic from the time-correlation image, the characteristic corresponding to a distribution of normal vectors to an inspection target surface and serving to detect an abnormality based on at least either a difference from a surrounding area or a difference from a reference surface.

Abstract: A frame fixing jig for mounting on a chuck table has a chuck portion for holding a workpiece in an annular frame, and a body portion for supporting the chuck portion. A frame support member (FSM) supports the annular frame, and a ring presses the frame against the FSM. The FSM has a through hole. The ring has an annular base portion and an engaging portion. The engaging portion can be inserted through the through hole, thereby engaging the FSM. The engaging portion includes a rotating shaft extending through the annular base portion, a knob fixed to the upper end of the shaft, and a plate fixed to the lower end. The surface around the lower end of the through hole or the upper surface of the plate is formed with an inclined surface for lowering the rotating shaft by rotating the plate inserted through the through hole.

Abstract: An image processing device includes a storage unit, an initial setting unit configured to store a position of an optical axis neighborhood point in a first image obtained by the imaging unit in the storage unit as an initial position of a specific point in the first image in association with image features of a surrounding area of the optical axis neighborhood point, a search unit configured to search for a corresponding point of the specific point in a second image obtained by the imaging unit based on the image features of the surrounding area of the specific point stored in the storage unit, and an output unit configured to output a position of the corresponding point in the second image as a position of the reference point in the second image.

Abstract: The disclosure relates to Compounds of Formula (I) and pharmaceutically acceptable derivatives thereof, where R1, R4, R8, R9, and m are as defined herein, compositions comprising an effective amount of a Compound of Formula (I) or a pharmaceutically acceptable derivative thereof, and methods for treating or preventing a condition such as pain, pain associated with osteoarthritis, osteoarthritis, UI, an ulcer, IBD, and IBS, comprising administering to an animal in need thereof an effective amount of a Compound of Formula (I) or a pharmaceutically acceptable derivative thereof.

Abstract: The present invention provides a process for preparation of the compound of formula (VI), wherein each symbol is as defined in the specification, without using any intermediate compound showing mutagenicity. The process comprises salt formation of the intermediate compound of formula (I) with acid to enable optical resolution to isolate the intermediate compound of formula (II) in a stereo-selective manner.

Abstract: To provide SOFC and method for manufacturing same, capable of preventing breakage of fuel cell electrodes, and of securing an electrical connection between fuel cells and a current collector. SOFC 1 comprising a cell array composed of fuel cells 16, and current collector 82 connected to electrodes formed on fuel cells 16, wherein current collector 82 is a metal plate on which attaching holes 84 are formed; elastic pieces 84a are provided on each attaching hole 84; current collector 82 is attached to the cell array using elastic pieces 84a, by the insertion of fuel cell 16 into attaching holes 84; and elastic pieces 84a are affixed to fuel cells 16 by electrode protective layer 152 so that the positions of elastic pieces 84a are not displaced relative to the electrodes on fuel cells 16.

Abstract: A solid oxide fuel cell stack includes a support, a plurality of power generation elements provided on a surface of the support, the plurality of power generation elements connected in series, each including at least a fuel electrode, a solid electrolyte, and an air electrode stacked in that order, and an interconnector that electrically connects an air electrode in one of adjacent power generation elements to a fuel electrode in the other power generation element. A solid electrolyte in adjacent one power generation element is provided between a fuel electrode in the adjacent one power generation element and the fuel electrode in the adjacent other power generation element, and an insulating member is provided at a position that is on the solid electrolyte in the adjacent one power generation element and between the air electrode in the adjacent one power generation element and the solid electrolyte therein.

Abstract: A frame fixing jig for mounting on a chuck table has a chuck portion for holding a workpiece in an annular frame, and a body portion for supporting the chuck portion. A frame support member (FSM) supports the annular frame, and a ring presses the frame against the FSM. The FSM has a through hole. The ring has an annular base portion and an engaging portion. The engaging portion can be inserted through the through hole, thereby engaging the FSM. The engaging portion includes a rotating shaft extending through the annular base portion, a knob fixed to the upper end of the shaft, and a plate fixed to the lower end. The surface around the lower end of the through hole or the upper surface of the plate is formed with an inclined surface for lowering the rotating shaft by rotating the plate inserted through the through hole.

Abstract: To provide a method for manufacturing SOFC, capable of preventing breakage of fuel cell electrodes, and of securing an electrical connection between fuel cells and a current collector. Step for forming electrode protective layers 152 on electrodes formed on fuel cells 16, modularization step for forming a cell array, and attaching step for attaching a current collector 82 to the cell array, wherein current collector 82 is a metal plate on which attaching holes 84 are formed for the insertion of fuel cells 16, elastic pieces 84a are formed at each attaching hole 84, fuel cells 16 are inserted into attaching holes 84, and current collector 82 is attached to the cell array by the elastic force; and protective layer 152 is constituted to prevent damage to electrodes caused by contact with elastic pieces.

Abstract: A solid oxide fuel cell stack includes a support, a plurality of power generation elements connected in series, each including a fuel electrode, a solid electrolyte, and an air electrode stacked in that order on the support, and an interconnector electrically connecting an air electrode in one of the two adjacent power generation elements to a fuel electrode in the other power generation element. A solid electrolyte for one of the power generation elements is provided on the downside of the interconnector provided on the downside of the air electrode in the one power generation element so that the solid electrolyte is joined to the interconnector, and a solid electrolyte for the other power generation element is provided on the upper side of the interconnector provided on the upper side of the fuel electrode for the other power generation element so that the solid electrolyte is joined to the interconnector.

Abstract: The disclosure relates to Compounds of Formula (I) and pharmaceutically acceptable derivatives thereof, where R1, R4, R8, R9, and m are as defined herein, compositions comprising an effective amount of a Compound of Formula (I) or a pharmaceutically acceptable derivative thereof, and methods for treating or preventing a condition such as pain, pain associated with osteoarthritis, osteoarthritis, UI, an ulcer, IBD, and IBS, comprising administering to an animal in need thereof an effective amount of a Compound of Formula (I) or a pharmaceutically acceptable derivative thereof.

Abstract: An inspection system of an embodiment includes: a planar illumination unit that temporally varies an intensity of light in a periodic manner by spatially moving a stripe pattern of the intensity of light; a time-correlation image generator that generates a time-correlation image with a time-correlation camera or an image capturing system that performs an operation equivalent to that of the time-correlation camera; and a calculation processor that calculates a characteristic from the time-correlation image, the characteristic corresponding to a distribution of normal vectors to an inspection target surface and serving to detect an abnormality based on at least either a difference from a surrounding area or a difference from a reference surface.